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Philip Needleman

Active 1965–2002

84
Papers
20,222
Citations
78
h-index
84
i10-index

Citations

Citations per year for Philip Needleman1969: 3 citations1970: 2 citations1971: 3 citations1972: 3 citations1973: 4 citations1974: 12 citations1975: 15 citations1976: 36 citations1977: 102 citations1978: 89 citations1979: 101 citations1980: 94 citations1981: 91 citations1982: 63 citations1983: 83 citations1984: 140 citations1985: 202 citations1986: 209 citations1987: 143 citations1988: 144 citations1989: 132 citations1990: 106 citations1991: 118 citations1992: 127 citations1993: 81 citations1994: 148 citations1995: 176 citations1996: 194 citations1997: 129 citations1998: 163 citations1999: 145 citations2000: 176 citations2001: 121 citations2002: 121 citations2003: 101 citations2004: 101 citations2005: 92 citations2006: 66 citations2007: 60 citations2008: 52 citations2009: 41 citations2010: 46 citations2011: 54 citations2012: 28 citations2013: 30 citations2014: 20 citations2015: 28 citations2016: 17 citations2017: 21 citations2018: 11 citations2019: 47 citations2020: 51 citations2021: 37 citations2022: 35 citations2023: 17 citations2024: 25 citations2025: 17 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 1,593 citing papers, 45.1% of this breakdownUnited Kingdom: 288 citing papers, 8.2% of this breakdownJapan: 247 citing papers, 7% of this breakdownGermany: 191 citing papers, 5.4% of this breakdownCanada: 154 citing papers, 4.4% of this breakdownItaly: 105 citing papers, 3% of this breakdownChina: 100 citing papers, 2.8% of this breakdownFrance: 81 citing papers, 2.3% of this breakdownAustralia: 66 citing papers, 1.9% of this breakdownSweden: 56 citing papers, 1.6% of this breakdownIndia: 54 citing papers, 1.5% of this breakdownNetherlands: 48 citing papers, 1.4% of this breakdown
0%45.1%Other 15.4%

Institutions

Fields

  • Medicine59.6%
  • Biochemistry, Genetics and Molecular Biology19.1%
  • Nursing6.8%
  • Neuroscience5.4%
  • Immunology and Microbiology2.9%
  • Agricultural and Biological Sciences1.5%
  • Other4.7%

Topics

  • Inflammatory mediators and NSAID effects10.3%
  • Eicosanoids and Hypertension Pharmacology6.8%
  • Nitric Oxide and Endothelin Effects4.5%
  • Estrogen and related hormone effects3.4%
  • Fatty Acid Research and Health3.3%
  • Heart Failure Treatment and Management2.6%
  • Other69.1%

Coauthors

All papers

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  1. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.

    Authors: Jianmin Fu, Jaime L. Masferrer, Karen Seibert, A Raz, Philip Needleman - Journal of Biological Chemistry 1990 cited by 943

  2. Differential metabolism of dihomo-γ-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2

    Authors: Galit Levin, Kevin L. Duffin, Mark G. Obukowicz, Susan L. HUMMERT, Hideji Fujiwara, Philip Needleman, Amiram Raz - Biochemical Journal 2002 cited by 86

  3. Nitric oxide activates cyclooxygenase enzymes.

    Authors: Daniela Salvemini, Thomas P. Misko, Jaime L. Masferrer, Karen Seibert, Mark G. Currie, Philip Needleman - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 1,404

  4. ARACHIDONIC ACID METABOLISM

    Authors: Philip Needleman, John Truk, Barbara A. Jakschik, Aubrey R. Morrison, J B Lefkowith - Annual Review of Biochemistry 1986 cited by 1,790

  5. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice.

    Authors: Mark G. Obukowicz, D. Welsch, W. J. Salsgiver, Cynthia L. Martin-Berger, K Chinn, Kevin L. Duffin, A Raz, Philip Needleman - 1998 cited by 103

  6. Triene prostaglandins: Prostacyclin and thromboxane biosynthesis and unique biological properties

    Authors: Philip Needleman, Amiram Raz, Mark S. Minkes, James A. Ferrendelli, Howard Sprecher - National Academy of Sciences, Proceedings of the National Academy of Sciences 1979 cited by 784

  7. Thromboxanes: Selective Biosynthesis and Distinct Biological Properties

    Authors: Philip Needleman, Mark S. Minkes, Amiram Raz - Science 1976 cited by 390

  8. Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis.

    Authors: Alice P. Pentland, Philip Needleman - Journal of Clinical Investigation 1986 cited by 206

  9. Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides

    Authors: Philip Needleman, Salvador Moncada, S Bunting, John R. Vane, Mats Hámberg, Bengt Samuelsson - Nature 1976 cited by 526

  10. Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme.

    Authors: Jaime L. Masferrer, Karen Seibert, Ben S. Zweifel, Philip Needleman - National Academy of Sciences, Proceedings of the National Academy of Sciences 1992 cited by 463

  11. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation.

    Authors: Daniela Salvemini, Karen Seibert, Jaime L. Masferrer, Thomas P. Misko, Mark G. Currie, Philip Needleman - Journal of Clinical Investigation 1994 cited by 309

  12. SULFHYDRYL REQUIREMENT FOR RELAXATION OF VASCULAR SMOOTH MUSCLE

    Authors: Philip Needleman, Barbara A. Jakschik, Eugene M. Johnson - Journal of Pharmacology and Experimental Therapeutics 1973 cited by 255

  13. Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors.

    Authors: Daniela Salvemini, Pamela T. Manning, Ben S. Zweifel, Karen Seibert, Jane R. Connor, Mark G. Currie, Philip Needleman, Jaime L. Masferrer - Journal of Clinical Investigation 1995 cited by 217

  14. Cardiac and Coronary Prostaglandin Synthesis and Function

    Authors: Philip Needleman, Gabor Kaley - New England Journal of Medicine 1978 cited by 160

  15. Paradoxical conservation of cardiac and renal arachidonate content in essential fatty acid deficiency.

    Authors: J B Lefkowith, V Flippo, Howard Sprecher, Philip Needleman - Journal of Biological Chemistry 1985 cited by 126

  16. Activation of vagal depressor reflexes by atriopeptins inhibits renal sympathetic nerve activity

    Authors: Peter Thorén, Allyn L. Mark, Donald A. Morgan, Timothy P. O’Neill, Philip Needleman, Michael J. Brody - American Journal of Physiology-Heart and Circulatory Physiology 1986 cited by 116

  17. Dihomo-prostaglandins and -thromboxane. A prostaglandin family from adrenic acid that may be preferentially synthesized in the kidney.

    Authors: Howard Sprecher, M VanRollins, F.F. Sun, Angela Wyche, Philip Needleman - Journal of Biological Chemistry 1982 cited by 76

  18. Bioactive Cardiac Substances: Potent Vasorelaxant Activity in Mammalian Atria

    Authors: Mark G. Currie, David M. Geller, Barbara R. Cole, John G. Boylan, Wu Yu-Sheng, S W Holmberg, Philip Needleman - Science 1983 cited by 710

  19. Purification and Sequence Analysis of Bioactive Atrial Peptides (Atriopeptins)

    Authors: Mark G. Currie, David M. Geller, Barbara R. Cole, Ned R. Siegel, Kam F. Fok, Steven P. Adams, Shad R. Eubanks, Gerald R. Galluppi, Philip Needleman - Science 1984 cited by 527

  20. MECHANISM OF TOLERANCE DEVELOPMENT TO ORGANIC NITRATES

    Authors: Philip Needleman, Eugene M. Johnson - Journal of Pharmacology and Experimental Therapeutics 1973 cited by 499

  21. Atriopeptin: A Cardiac Hormone Intimately Involved in Fluid, Electrolyte, and Blood-Pressure Homeostasis

    Authors: Franklin H. Epstein, Franklin H. Epstein, Philip Needleman, James E. Greenwald - New England Journal of Medicine 1986 cited by 489

  22. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase).

    Authors: John P. Merlie, D Fagan, Jacqueline L. Mudd, Philip Needleman - Journal of Biological Chemistry 1988 cited by 431

  23. Regulation of fibroblast cyclooxygenase synthesis by interleukin-1.

    Authors: A Raz, Angela Wyche, Ned R. Siegel, Philip Needleman - Journal of Biological Chemistry 1988 cited by 400

  24. Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice.

    Authors: Jaime L. Masferrer, Ben S. Zweifel, Karen Seibert, Philip Needleman - Journal of Clinical Investigation 1990 cited by 398