litlas
Log inCreate account

Rienk Offringa

Active 1989–2025

99
Papers
19,622
Citations
78
h-index
99
i10-index

Citations

Citations per year for Rienk Offringa1979: 1 citations1990: 5 citations1991: 22 citations1992: 19 citations1993: 17 citations1994: 14 citations1995: 24 citations1996: 24 citations1997: 18 citations1998: 67 citations1999: 134 citations2000: 233 citations2001: 213 citations2002: 294 citations2003: 280 citations2004: 280 citations2005: 262 citations2006: 218 citations2007: 238 citations2008: 245 citations2009: 217 citations2010: 198 citations2011: 175 citations2012: 204 citations2013: 160 citations2014: 175 citations2015: 165 citations2016: 166 citations2017: 121 citations2018: 100 citations2019: 330 citations2020: 376 citations2021: 413 citations2022: 349 citations2023: 245 citations2024: 368 citations2025: 246 citations2026: 8 citations1980–1989: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,261 citing papers, 31.7% of this breakdownChina: 601 citing papers, 8.4% of this breakdownGermany: 562 citing papers, 7.9% of this breakdownNetherlands: 497 citing papers, 7% of this breakdownUnited Kingdom: 426 citing papers, 6% of this breakdownFrance: 318 citing papers, 4.5% of this breakdownItaly: 224 citing papers, 3.1% of this breakdownAustralia: 199 citing papers, 2.8% of this breakdownJapan: 191 citing papers, 2.7% of this breakdownSwitzerland: 188 citing papers, 2.6% of this breakdownCanada: 172 citing papers, 2.4% of this breakdownSweden: 120 citing papers, 1.7% of this breakdown
0%31.7%Other 19.2%

Institutions

Fields

  • Immunology and Microbiology46.9%
  • Medicine33.3%
  • Biochemistry, Genetics and Molecular Biology17.1%
  • Engineering0.8%
  • Neuroscience0.8%
  • Agricultural and Biological Sciences0.3%
  • Other0.8%

Topics

  • Immunotherapy and Immune Responses18.3%
  • Immune Cell Function and Interaction9.8%
  • T-cell and B-cell Immunology8.6%
  • Cancer Immunotherapy and Biomarkers7.5%
  • CAR-T cell therapy research5.3%
  • vaccines and immunoinformatics approaches3.4%
  • Other47.1%

Coauthors

All papers

Open in search
  1. The expanding role for small molecules in immuno-oncology

    Authors: Rienk Offringa, Lisa Kötzner, Bayard R. Huck, Klaus Urbahns - Nature Reviews Drug Discovery 2022 cited by 121

  2. T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

    Authors: Stephen P. Schoenberger, René E. M. Toes, Ellen I. H. van der Voort, Rienk Offringa, Cornelis J.M. Melief - Nature 1998 cited by 2,624

  3. Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

    Authors: Gemma G. Kenter, Marij J.P. Welters, A. Rob P.M. Valentijn, Margriet J. Löwik, Dorien M. A. Berends-van der Meer, Annelies P.G. Vloon, Farah Essahsah, Lorraine M. Fathers, Rienk Offringa, Jan W. Drijfhout, Amon R. Wafelman, Jaap Oostendorp, Gert Jan Fleuren, Sjoerd H. van der Burg, Cornelis J.M. Melief - New England Journal of Medicine 2009 cited by 1,085

  4. Prevailing Role of Contact Guidance in Intrastromal T-cell Trapping in Human Pancreatic Cancer

    Authors: Natalie Hartmann, Nathalia A. Giese, Thomas Giese, Isabel Poschke, Rienk Offringa, Jens Werner, Eduard Ryschich - Clinical Cancer Research 2014 cited by 244

  5. Superior induction of anti‐tumor CTL immunity by extended peptide vaccines involves prolonged, DC‐focused antigen presentation

    Authors: Martijn S. Bijker, Susan J. F. van den Eeden, Kees L. M. C. Franken, Cornelis J.M. Melief, Sjoerd H. van der Burg, Rienk Offringa - European Journal of Immunology 2008 cited by 231

  6. Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy

    Authors: Christina Kober, Julian Roewe, Norbert Schmees, Lars Roese, Ulrike Roehn, Benjamin Bader, Detlef Stoeckigt, Florian Prinz, Mátyás Gorjánácz, Helge G. Roider, Catherine Olesch, Gabriele Leder, Horst Irlbacher, Ralf Lesche, Julien Lefranc, Mine Oezcan-Wahlbrink, Ankita Sati Batra, Nirmeen Elmadany, Rafael Carretero, Katharina Sahm, Iris Oezen, Frederik Cichon, Daniel Baumann, Ahmed Sadik, Christiane A. Opitz, Hilmar Weinmann, Ingo V. Hartung, Bertolt Kreft, Rienk Offringa, Michael Platten, Ilona Gutcher - Journal for ImmunoTherapy of Cancer 2023 cited by 82

  7. Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy

    Authors: Chin Leng Tan, Katharina A.M. Lindner, Tamara Boschert, Zibo Meng, Aaron Rodriguez Ehrenfried, Alice De Roia, Gordon Haltenhof, A. Faenza, Francesco Imperatore, Lukas Bunse, John M. Lindner, Richard P. Harbottle, Miriam Ratliff, Rienk Offringa, Isabel Poschke, Michael Platten, Edward W. Green - Nature Biotechnology 2024 cited by 71

  8. Characterization of single neurons reprogrammed by pancreatic cancer

    Authors: Vera Thiel, Simon Renders, Jasper Panten, Nicolas Dross, Katharina Bauer, Daniel Azorín, Vanessa Henriques, Vanessa Vogel, Corinna Klein, Aino‐Maija Leppä, Isabel Barriuso-Ortega, Jonas Schwickert, Iordanis Ourailidis, Julian Mochayedi, Jan‐Philipp Mallm, Carsten Müller‐Tidow, Hannah Monyer, John P. Neoptolemos, Thilo Hackert, Oliver Stegle, Duncan T. Odom, Rienk Offringa, Albrecht Stenzinger, Frank Winkler, Martin R. Sprick, Andreas Trumpp - Nature 2025 cited by 101

  9. CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund’s Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity

    Authors: Martijn S. Bijker, Susan J. F. van den Eeden, Kees L. M. C. Franken, Cornelis J.M. Melief, Rienk Offringa, Sjoerd H. van der Burg - The Journal of Immunology 2007 cited by 282

  10. ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation

    Authors: Rui Sun, Zibo Meng, Hye-Yoon Lee, Rienk Offringa, Christof Niehrs - Cell chemical biology 2023 cited by 40

  11. The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones

    Authors: Isabel Poschke, Jessica C. Hassel, Aaron Rodriguez-Ehrenfried, Katharina A.M. Lindner, Ignacio Heras‐Murillo, Lena M. Appel, Johanna Lehmann, Tanja Lövgren, Stina L. Wickström, Claudia Lauenstein, Jasmin Roth, Anna‐Katharina König, John B.A.G. Haanen, Joost van den Berg, Rolf Kiessling, Frank Bergmann, Michael Floßdorf, Oliver Strobel, Rienk Offringa - Clinical Cancer Research 2020 cited by 90

  12. Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma

    Authors: Isabel Poschke, Marta Faryna, Frank Bergmann, Michael Floßdorf, Claudia Lauenstein, Jennifer Hermes, Ulf Hinz, Thomas Hank, Roland Ehrenberg, Michael Volkmar, Martin Löewer, Hanno Glimm, Thilo Hackert, Martin R. Sprick, Thomas Höfer, Andreas Trumpp, Niels Halama, Jessica C. Hassel, Oliver Strobel, Markus W. Büchler, Uğur Şahin, Rienk Offringa - OncoImmunology 2016 cited by 96

  13. High Number of Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer

    Authors: Sytse J. Piersma, Ekaterina S. Jordanova, Mariëtte I.E. van Poelgeest, Kitty M.C. Kwappenberg, Jeanette M. van der Hulst, Jan W. Drijfhout, Cornelis J.M. Melief, Gemma G. Kenter, Gert Jan Fleuren, Rienk Offringa, Sjoerd H. van der Burg - Cancer Research 2007 cited by 419

  14. Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

    Authors: Daniel Baumann, Tanja Hägele, Julian Mochayedi, Jennifer Drebant, Caroline Vent, Sven Blobner, Julia Han Noll, Irena Nickel, Corinna Schumacher, Sophie Luise Boos, Aline Daniel, Susann Wendler, Michael Volkmar, Oliver Strobel, Rienk Offringa - Nature Communications 2020 cited by 73

  15. Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer

    Authors: Zibo Meng, Aaron Rodriguez Ehrenfried, Chin Leng Tan, Laura K. Steffens, Hannes Kehm, Stefan Zens, Claudia Lauenstein, A. Paul, Marius Schwab, Jonas D. Förster, Mogjiborahman Salek, Angelika B. Riemer, Heshui Wu, Christoph Eckert, Carl-Stephan Leonhardt, Oliver Strobel, Michael Volkmar, Isabel Poschke, Rienk Offringa - Science Translational Medicine 2023 cited by 44

  16. Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

    Authors: Jan Paul Medema, Joan de Jong, Lucy T.C. Peltenburg, Els M.E. Verdegaal, Arko Gorter, Sandra A. Bres, Kees L. M. C. Franken, Michael Hahne, Juan Pablo Albar, Cornelis J.M. Melief, Rienk Offringa - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 350

  17. T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction

    Authors: J. Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf‐Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin V. Luetke-Eversloh, Sven Golfier, Oliver von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse N. Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda - 2022 cited by 35

  18. Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides

    Authors: Sander Zwaveling, Sandra C. Ferreira Mota, Jan Nouta, Mark E. Johnson, Grayson B. Lipford, Rienk Offringa, Sjoerd H. van der Burg, Cornelis J.M. Melief - The Journal of Immunology 2002 cited by 415

  19. p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition

    Authors: Daniel Baumann, Jennifer Drebant, Tanja Hägele, Luisa Burger, Clara Serger, Claudia Lauenstein, Przemyslaw Dudys, Gerrit Erdmann, Rienk Offringa - Journal for ImmunoTherapy of Cancer 2021 cited by 51

  20. T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction

    Authors: Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin Luetke-Eversloh, Sven Golfier, Oliver Von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse Nur-Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda - OncoImmunology 2021 cited by 37

  21. CD25+ cell depletion hastens the onset of severe disease in collagen‐induced arthritis

    Authors: Mary E. Morgan, Roger P.M. Sutmuller, Hendrik J. Witteveen, Leonie M. van Duivenvoorde, Eric Zanelli, Cornelis J.M. Melief, A. J. Snijders, Rienk Offringa, René R. P. de Vries, René E. M. Toes - Arthritis & Rheumatism 2003 cited by 303

  22. Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses

    Authors: Roger P.M. Sutmuller, Leonie M. van Duivenvoorde, Andrea van Elsas, Ton N. Schumacher, Manon E. Wildenberg, James P. Allison, René E. M. Toes, Rienk Offringa, Cornelis J.M. Melief - The Journal of Experimental Medicine 2001 cited by 1,013

  23. Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine

    Authors: Marij J.P. Welters, Gemma G. Kenter, Sytse J. Piersma, Annelies P.G. Vloon, Margriet J.G. Löwik, Dorien M. A. Berends-van der Meer, Jan W. Drijfhout, A. Rob P.M. Valentijn, Amon R. Wafelman, Jaap Oostendorp, Gert Jan Fleuren, Rienk Offringa, Cornelis J.M. Melief, Sjoerd H. van der Burg - Clinical Cancer Research 2008 cited by 368

  24. Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.

    Authors: René E. M. Toes, Rienk Offringa, R. Blom, Cornelis J.M. Melief, W. Martin Kast - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 cited by 293