Rima Rozen
Active 1985–2024
- 71
- Papers
- 21,643
- Citations
- 64
- h-index
- 69
- i10-index
Citations
Citation sources
Countries
Institutions
- McGill University1.1%
- Harvard University1%
- Radboud University Nijmegen0.8%
- Inserm0.7%
- Brigham and Women's Hospital0.7%
- Cornell University0.7%
- Other95%
Fields
- Medicine76.1%
- Biochemistry, Genetics and Molecular Biology18.4%
- Neuroscience1.6%
- Agricultural and Biological Sciences0.7%
- Environmental Science0.7%
- Immunology and Microbiology0.5%
- Other2%
Topics
- Folate and B Vitamins Research19.9%
- Esophageal and GI Pathology3.9%
- Epigenetics and DNA Methylation3.9%
- Metabolism and Genetic Disorders3.1%
- Pregnancy and preeclampsia studies2.3%
- Iron Metabolism and Disorders2.2%
- Other64.7%
Coauthors
- Daniel Leclerc9
- Jacob Selhub9
- Karen E. Christensen8
- Marie A. Caudill8
- Phyllis Frosst8
- Benedicte Christensen7
- David S. Rosenblatt7
- Jacques Genest7
- Olga Malysheva7
- Bernd Schwahn6
- Philippe Goyette6
- Liyuan Deng5
- Qing Wu5
- Robert W. Platt5
- Rowena G. Matthews5
- Teodoro Bottiglieri5
- Henk J. Blom4
- Marta Cosín‐Tomás4
- Pamela V. Tran4
- Roy A. Gravel4
- Timothy A. Garrow4
- Yan Luan4
- Zhoutao Chen4
- Alaina M. Reagan3
All papers
- A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
Authors: Phyllis Frosst, Henk J. Blom, Renate Milos, Philippe Goyette, Christal A. Sheppard, Rowena G. Matthews, GodfriedHJ Boers, Martin den Heijer, Leo A. J. Kluijtmans, L.P. van den Heuve, Rima Rozen - Nature Genetics 1995 cited by 5,707
- Shifting landscapes of human MTHFR missense-variant effects
Authors: Jochen Weile, Nishka Kishore, Song Sun, Ranim Maaieh, Marta Verby, Roujia Li, Iosifina Fotiadou, Julia Kitaygorodsky, Yingzhou Wu, Alexander Holenstein, Céline Bürer, Linnea Blomgren, Shan Yang, Robert L. Nussbaum, Rima Rozen, David Watkins, Marinella Gebbia, Viktor Kožich, Michael Garton, D. Sean Froese, Frederick P. Roth - The American Journal of Human Genetics 2021 cited by 80
- Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification
Authors: Philippe Goyette, James S. Sumner, Renate Milos, Alessandra M.V. Duncan, David S. Rosenblatt, Rowena G. Matthews, Rima Rozen - Nature Genetics 1994 cited by 903
- Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase
Authors: Kazuhiro Yamada, Zhoutao Chen, Rima Rozen, Rowena G. Matthews - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 412
- High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice
Authors: Karen E. Christensen, Leonie G. Mikael, Kit‐Yi Leung, Nancy Lévesque, Liyuan Deng, Qing Wu, Olga Malysheva, Ana F. Best, Marie A. Caudill, Nicholas D. E. Greene, Rima Rozen - American Journal of Clinical Nutrition 2015 cited by 163
- Infertility in 5,10-Methylenetetrahydrofolate Reductase (MTHFR)-Deficient Male Mice Is Partially Alleviated by Lifetime Dietary Betaine Supplementation1
Authors: Tamara Kelly, Oana R. Neaga, Bernd Schwahn, Rima Rozen, Jacquetta M. Trasler - Biology of Reproduction 2004 cited by 136
- Oncogenic role of PDK4 in human colon cancer cells
Authors: Daniel Leclerc, Diep Pham, Nancy Lévesque, May Truongcao, William D. Foulkes, Carmen Sapienza, Rima Rozen - British Journal of Cancer 2017 cited by 118
- High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring
Authors: Renata H. Bahous, Nafisa M. Jadavji, Liyuan Deng, Marta Cosín‐Tomás, Jessica W. Lu, Olga Malysheva, Kit‐Yi Leung, Ming‐Kai Ho, Mercè Pallàs, Perla Kaliman, Nicholas D. E. Greene, Barry J. Bedell, Marie A. Caudill, Rima Rozen - Human Molecular Genetics 2017 cited by 84
- Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)
Authors: Philippe Goyette, Aditya Pai, Renate Milos, Phyllis Frosst, Pamela V. Tran, Zhoutao Chen, Manuel Chan, Rima Rozen - Mammalian Genome 1998 cited by 361
- A Second Genetic Polymorphism in Methylenetetrahydrofolate Reductase (MTHFR) Associated with Decreased Enzyme Activity
Authors: Ilan Weisberg, Pamela V. Tran, Benedicte Christensen, Sahar Sibani, Rima Rozen - Molecular Genetics and Metabolism 1998 cited by 1,285
- The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects
Authors: Karen E. Christensen, Charles Rohlicek, Grégor Andelfinger, Jacques L. Michaud, Jean‐Luc Bigras, Andréa Richter, Robert E. MacKenzie, Rima Rozen - Human Mutation 2008 cited by 108
- The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice
Authors: Alaina M. Reagan, Karen E. Christensen, Leah Graham, Amanda A. Bedwell, Kierra Eldridge, Rachael Speedy, Lucas L. Figueiredo, Scott C. Persohn, Teodoro Bottiglieri, Kwangsik Nho, Michael Sasner, Paul R. Territo, Rima Rozen, Gareth R. Howell - Journal of Cerebral Blood Flow & Metabolism 2022 cited by 19
- Relation Between Folate Status, a Common Mutation in Methylenetetrahydrofolate Reductase, and Plasma Homocysteine Concentrations
Authors: Paul F. Jacques, Andrew G. Bostom, Roger R. Williams, R. Curtis Ellison, John H. Eckfeldt, Irwin H. Rosenberg, Jacob Selhub, Rima Rozen - Circulation 1996 cited by 1,401
- Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.
Authors: Jing Ma, Meir J. Stampfer, Edward L. Giovannucci, Carlos Artigas, David J. Hunter, Charles S. Fuchs, Walter C. Willett, Jacob Selhub, Charles H. Hennekens, Rima Rozen - 1997 cited by 794
- A Common Variant in Methionine Synthase Reductase Combined with Low Cobalamin (Vitamin B12) Increases Risk for Spina Bifida
Authors: Aaron Wilson, Robert W. Platt, Qing Wu, Daniel Leclerc, Benedicte Christensen, Hong Yang, Roy A. Gravel, Rima Rozen - Molecular Genetics and Metabolism 1999 cited by 440
- Epigenome-Wide Association of Liver Methylation Patterns and Complex Metabolic Traits in Mice
Authors: Luz D. Orozco, Marco Morselli, Liudmilla Rubbi, Weilong Guo, James Go, Huwenbo Shi, David López, Nicholas A. Furlotte, Brian J. Bennett, Charles R. Farber, Anatole Ghazalpour, Michael Q. Zhang, Renata H. Bahous, Rima Rozen, Aldons J. Lusis, Matteo Pellegrini - Cell Metabolism 2015 cited by 106
- Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: Critical role of S-adenosyl methionine
Authors: Amy Chan, Flaubert Tchantchou, Valerie Graves, Rima Rozen, Thomas B. Shea - The journal of nutrition health & aging 2008 cited by 89
- High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis
Authors: Daniel Leclerc, Jaroslav Jelı́nek, Karen E. Christensen, Jean‐Pierre J. Issa, Rima Rozen - The Journal of Nutritional Biochemistry 2020 cited by 17
- Elevated Homocysteine Reduces Apolipoprotein A-I Expression in Hyperhomocysteinemic Mice and in Males With Coronary Artery Disease
Authors: Leonie G. Mikael, Jacques Genest, Rima Rozen - Circulation Research 2006 cited by 164
- Glycine N‐methyltransferase deficiency: A novel inborn error causing persistent isolated hypermethioninaemia
Authors: S. Harvey Mudd, R. Cerone, M. C. Schiaffino, A. R. Fantasia, Giuseppe Minniti, U. Caruso, Renata Lorini, David Watkins, Nora V. Matiaszuk, David S. Rosenblatt, Bernd Schwahn, Rima Rozen, Leighton LeGros, Malak Kotb, Antonieta Capdevila, Zigmund Luka, James D. Finkelstein, Albert Tangerman, Sally P. Stabler, Robert H. Allen, Conrad Wagner - Journal of Inherited Metabolic Disease 2001 cited by 150
- Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism
Authors: Karen E. Christensen, Qing Wu, Xiaoling Wang, Liyuan Deng, Marie A. Caudill, Rima Rozen - Journal of Nutrition 2010 cited by 110
- Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism
Authors: Marta Cosín‐Tomás, Yan Luan, Daniel Leclerc, Olga Malysheva, Nidia Lauzon, Renata H. Bahous, Karen E. Christensen, Marie A. Caudill, Rima Rozen - Nutrients 2020 cited by 35
- Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Sex-Specific Gene Expression in Brain of Young Mice and Embryos
Authors: Yan Luan, Marta Cosín‐Tomás, Daniel Leclerc, Olga Malysheva, Marie A. Caudill, Rima Rozen - Nutrients 2022 cited by 18
- Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Methyl Metabolism and in Sex‐Specific Placental Transcription Changes
Authors: Yan Luan, Daniel Leclerc, Marta Cosín‐Tomás, Olga Malysheva, Brandi Wasek, Teodoro Bottiglieri, Marie A. Caudill, Rima Rozen - Molecular Nutrition & Food Research 2021 cited by 17
