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Frederick P. Roth

Active 1998–2025

129
Papers
38,614
Citations
80
h-index
119
i10-index

Citations

Citations per year for Frederick P. Roth1924: 1 citations1968: 1 citations1976: 1 citations1982: 2 citations1984: 1 citations1987: 1 citations1988: 1 citations1990: 2 citations1994: 2 citations1995: 2 citations1996: 4 citations1998: 4 citations1999: 14 citations2000: 27 citations2001: 32 citations2002: 44 citations2003: 65 citations2004: 222 citations2005: 396 citations2006: 442 citations2007: 530 citations2008: 615 citations2009: 648 citations2010: 745 citations2011: 776 citations2012: 806 citations2013: 646 citations2014: 566 citations2015: 598 citations2016: 605 citations2017: 604 citations2018: 563 citations2019: 1,112 citations2020: 1,170 citations2021: 1,149 citations2022: 863 citations2023: 663 citations2024: 1,005 citations2025: 545 citations2026: 42 citations1925–1967: no citations, so these years are not shown1969–1975: no citations, so these years are not shown1977–1981: no citations, so these years are not shown1983: no citations, so this year is not shown1985–1986: no citations, so these years are not shown1989: no citations, so this year is not shown1991–1993: no citations, so these years are not shown1997: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 5,764 citing papers, 31.5% of this breakdownChina: 1,652 citing papers, 9% of this breakdownUnited Kingdom: 1,346 citing papers, 7.4% of this breakdownCanada: 1,143 citing papers, 6.3% of this breakdownGermany: 1,094 citing papers, 6% of this breakdownSpain: 573 citing papers, 3.1% of this breakdownFrance: 548 citing papers, 3% of this breakdownItaly: 489 citing papers, 2.7% of this breakdownIndia: 379 citing papers, 2.1% of this breakdownJapan: 373 citing papers, 2% of this breakdownAustralia: 360 citing papers, 2% of this breakdownSwitzerland: 343 citing papers, 1.9% of this breakdown
0%31.5%Other 23%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology69.9%
  • Medicine9.9%
  • Computer Science6.6%
  • Agricultural and Biological Sciences3.5%
  • Physics and Astronomy2.9%
  • Chemistry2.2%
  • Other5%

Topics

  • Bioinformatics and Genomic Networks11%
  • Computational Drug Discovery Methods3.9%
  • Gene expression and cancer classification3.3%
  • RNA and protein synthesis mechanisms3.2%
  • RNA Research and Splicing2.8%
  • Gene Regulatory Network Analysis2.6%
  • Other73.2%

Coauthors

All papers

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  1. A reference map of the human binary protein interactome

    Authors: Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoît Charloteaux, Dong-Sic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon-gang Choi, Claudia Colabella, Georges Coppin, Cassandra D'Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Tasan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood - Nature, Nat. 2020 cited by 1,346

  2. High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

    Authors: Traver Hart, Megha Chandrashekhar, Michael Aregger, Zachary Steinhart, Kevin R. Brown, Graham MacLeod, Monika Mis, Michal Zimmermann, Amélie Fradet‐Turcotte, Song Sun, Patricia Mero, Peter B. Dirks, Sachdev S. Sidhu, Frederick P. Roth, Olivia S. Rissland, Daniel Durocher, Stéphane Angers, Jason Moffat - Cell 2015 cited by 1,824

  3. MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect

    Authors: Daniel Esposito, Jochen Weile, Jay Shendure, Lea M. Starita, Anthony T. Papenfuss, Frederick P. Roth, Douglas M. Fowler, Alan F. Rubin - Genome biology 2019 cited by 279

  4. A Proteome-Scale Map of the Human Interactome Network

    Authors: Thomas Rolland, Murat Taşan, Benoît Charloteaux, Samuel Pevzner, Quan Zhong, Nidhi Sahni, S. Stephen Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan Dina Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Falter‐Braun, Marc Brehme, Martin Broly, Anne‐Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe‐Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric A. Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean‐Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-Ĺaszló Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal - Cell 2014 cited by 1,469

  5. Towards a proteome-scale map of the human protein–protein interaction network

    Authors: Jean‐François Rual, K. Venkatesan, Tong Hao, Tomoko Hirozane-Kishikawa, Amélie Dricot, Ning Li, Gabriel F. Berriz, Francis D. Gibbons, Matija Dreze, Nono Ayivi-Guedehoussou, Niels Klitgord, Christophe Simon, Mike Boxem, Stuart Milstein, Jennifer Rosenberg, Debra S. Goldberg, Lan V. Zhang, Sharyl L. Wong, Giovanni Franklin, Siming Li, Joanna S. Albala, Janghoo Lim, Carlene Fraughton, Estelle Llamosas, Sebiha Cevik, Camille Bex, Philippe Lamesch, Robert Sikorski, Jean Vandenhaute, Huda Y. Zoghbi, Alex Smolyar, Stephanie Bosak, Reynaldo Sequerra, Lynn Doucette‐Stamm, Michael E. Cusick, David E. Hill, Frederick P. Roth, Marc Vidal - Nature 2005 cited by 3,021

  6. Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

    Authors: Nidhi Sahni, S. Stephen Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe‐Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios Ioannis Karras, Yang Wang, I. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy Hiu Yi Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang‐Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San‐Miguel, Changyu Fan, Dawit Balcha, Amélie Dricot, Daniel M. Jordan, Jennifer Walsh, Akash Shah, Xinping Yang, Ani K. Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi‐Ashtiani, Luke Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-Ĺaszló Barabási, Benoît Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal - Cell 2015 cited by 650

  7. A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

    Authors: Manuel Irimia, Robert J. Weatheritt, Jonathan D. Ellis, Neelroop Parikshak, Thomas Gonatopoulos-Pournatzis, Mariana Babor, Mathieu Quesnel-Vallières, Javier Tapial, Bushra Raj, Dave O’Hanlon, Miriam Barrios‐Rodiles, Michael J.E. Sternberg, Sabine P. Cordes, Frederick P. Roth, Jeffrey L. Wrana, Daniel H. Geschwind, Benjamin J. Blencowe - Cell 2014 cited by 775

  8. An Atlas of Variant Effects to understand the genome at nucleotide resolution

    Authors: Douglas M. Fowler, David J. Adams, Anna L. Gloyn, William C. Hahn, Debora S. Marks, Lara A. Muffley, James T. Neal, Frederick P. Roth, Alan F. Rubin, Lea M. Starita, Matthew E. Hurles - Genome biology 2023 cited by 127

  9. Improved pathogenicity prediction for rare human missense variants

    Authors: Yingzhou Wu, Hanqing Liu, Roujia Li, Song Sun, Jochen Weile, Frederick P. Roth - The American Journal of Human Genetics 2021 cited by 183

  10. Chemical substructures that enrich for biological activity

    Authors: Justin Klekota, Frederick P. Roth - Bioinformatics, Bioinform. 2008 cited by 392

  11. Variant Interpretation: Functional Assays to the Rescue

    Authors: Lea M. Starita, Nadav Ahituv, Maitreya J. Dunham, Jacob O. Kitzman, Frederick P. Roth, Georg Seelig, Jay Shendure, Douglas M. Fowler - The American Journal of Human Genetics 2017 cited by 427

  12. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

    Authors: Xinping Yang, Jasmin Coulombe‐Huntington, Shuli Kang, Gloria Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran‐Frigola, Andrew MacWilliams, Samuel Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, S. Stephen Yi, Maria Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong Jasmine Zhou, Kourosh Salehi‐Ashtiani, Benoît Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal - Cell 2016 cited by 625

  13. An empirical framework for binary interactome mapping

    Authors: K. Venkatesan, Jean‐François Rual, Alexei Vázquez, Ulrich Stelzl, Irma Lemmens, Tomoko Hirozane-Kishikawa, Tong Hao, Martina Zenkner, Xiaofeng Xin, Kwang Il Goh, Muhammed A. Yıldırım, Nicolas Simonis, Kathrin Heinzmann, Fana Gebreab, Julie M. Sahalie, Sebiha Cevik, Christophe Simon, Anne Sophie de Smet, Elizabeth Dann, Alex Smolyar, Arunachalam Vinayagam, Haiyuan Yu, David Szeto, Heather Borick, Amélie Dricot, Niels Klitgord, Ryan R. Murray, Chenwei Lin, Maciej Łałowski, Jan Timm, Kirstin Rau, Charles Boone, Pascal Falter‐Braun, Michael E. Cusick, Frederick P. Roth, David E. Hill, Jan Tavernier, Erich E. Wanker, Albert-Ĺaszló Barabási, Marc Vidal - Nature Methods 2008 cited by 908

  14. A framework for exhaustively mapping functional missense variants

    Authors: Jochen Weile, Song Sun, Atina G. Coté, Jennifer J. Knapp, Marta Verby, Joseph Mellor, Yingzhou Wu, Carles Pons, Cassandra J. Wong, Natascha van Lieshout, Fan Yang, Murat Taşan, Guihong Tan, Shan Yang, Douglas M. Fowler, Robert L. Nussbaum, Jesse D. Bloom, Marc Vidal, David E. Hill, Patrick Aloy, Frederick P. Roth - Molecular Systems Biology 2017 cited by 235

  15. The Genetic Landscape of a Cell

    Authors: Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St.Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renée L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy H.Y. Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne‐Claude Gingras, Quaid Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda Andrews, Charles Boone - Science 2010 cited by 2,265

  16. Evidence for dynamically organized modularity in the yeast protein–protein interaction network

    Authors: Jing‐Dong J. Han, Nicolas Bertin, Tong Hao, Debra S. Goldberg, Gabriel F. Berriz, Lan V. Zhang, Denis Dupuy, Albertha J.M. Walhout, Michael E. Cusick, Frederick P. Roth, Marc Vidal - Nature 2004 cited by 1,848

  17. Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas

    Authors: Jochen Weile, Frederick P. Roth - Human Genetics 2018 cited by 195

  18. Scalable Functional Assays for the Interpretation of Human Genetic Variation

    Authors: Daniel Tabet, Victoria N. Parikh, Prashant Mali, Frederick P. Roth, Melina Claussnitzer - Annual Review of Genetics 2022 cited by 96

  19. Metabolic Signatures of Exercise in Human Plasma

    Authors: Gregory D. Lewis, Laurie Farrell, Malissa J. Wood, M.FuruS. Martinovic, Zoltàn Arany, Glenn C. Rowe, Amanda Souza, Susan Cheng, Elizabeth L. McCabe, Elaine Yang, Xu Shi, Rahul C. Deo, Frederick P. Roth, Aarti Asnani, Eugene P. Rhee, David M. Systrom, Marc J. Semigran, Ramachandran S. Vasan, Steven A. Carr, Thomas J. Wang, Marc S. Sabatine, Clary B. Clish, Robert E. Gerszten - Science Translational Medicine 2010 cited by 423

  20. Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions

    Authors: Paul Markus Müller, Juliane Rademacher, Richard D. Bagshaw, Celina Wortmann, Carolin Barth, Jakobus van Unen, Keziban Merve, Girolamo Giudice, Rebecca L. Eccles, Louise Heinrich, Patricia Pascual Vargas, Marta Sanchez-Castro, Lennart Brandenburg, Geraldine Mbamalu, Monika Tucholska, Lisa Spatt, Maciej T. Czajkowski, Robert-William Welke, Sunqu Zhang, Vivian Nguyen, Trëndelina Rrustemi, Philipp Trnka, Kiara Freitag, Brett Larsen, Oliver Popp, Philipp Mertins, Anne‐Claude Gingras, Frederick P. Roth, Karen Colwill, Chris Bakal, Olivier Pertz, Tony Pawson, Evangelia Petsalaki, Oliver Rocks - Nature Cell Biology 2020 cited by 270

  21. The Impact of Oncogenic EGFRvIII on the Proteome of Extracellular Vesicles Released from Glioblastoma Cells

    Authors: Dongsic Choi, Laura Montermini, Dae‐Kyum Kim, Brian Meehan, Frederick P. Roth, Janusz Rak - Molecular & Cellular Proteomics 2018 cited by 167

  22. Defining genetic interaction

    Authors: Ramamurthy Mani, Robert P. St.Onge, John L. Hartman, Guri Giaever, Frederick P. Roth - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 502

  23. Global Mapping of the Yeast Genetic Interaction Network

    Authors: Amy H.Y. Tong, Guillaume Lesage, Gary D. Bader, Huiming Ding, Hong Xu, Xiaofeng Xin, James D. Young, Gabriel F. Berriz, Renée L. Brost, Michael Chang, YiQun Chen, Xin Cheng, Gordon Chua, Helena Friesen, Debra S. Goldberg, Jennifer Haynes, Christine Humphries, Grace He, Shamiza Hussein, Lizhu Ke, Nevan J. Krogan, Zhijian Li, Joshua N. Levinson, Hong Lü, P Ménard, Christella Munyana, Ainslie B. Parsons, Owen Ryan, Raffi Tonikian, Tania Michelle Roberts, Anne‐Marie Sdicu, B. Jesse Shapiro, Bilal Sheikh, Bernhard Suter, Sharyl L. Wong, Lan V. Zhang, Hongwei Zhu, Christopher G. Burd, Sean Munro, Chris Sander, Jasper Rine, Jack Greenblatt, Matthias Peter, Anthony Bretscher, Graham Bell, Frederick P. Roth, Grant W. Brown, Brenda Andrews, Howard Bussey, Charles Boone - Science 2004 cited by 2,140

  24. High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

    Authors: Haiyuan Yu, Pascal Falter‐Braun, Muhammed A. Yıldırım, Irma Lemmens, K. Venkatesan, Julie M. Sahalie, Tomoko Hirozane-Kishikawa, Fana Gebreab, Na Li, Nicolas Simonis, Tong Hao, Jean‐François Rual, Amélie Dricot, Alexei Vázquez, Ryan R. Murray, Christophe Simon, Leah Tardivo, Stanley Tam, Nenad Svrzikapa, Changyu Fan, A. De Smet, Adriana Motyl, Michael E. Hudson, Juyong Park, Xiaofeng Xin, Michael E. Cusick, Troy Moore, Charlie Boone, M Snyder, Frederick P. Roth, Albert-Ĺaszló Barabási, Jan Tavernier, David E. Hill, Marc Vidal - Science 2008 cited by 1,433