Jason Moffat
Active 1997–2026
- 116
- Papers
- 28,935
- Citations
- 74
- h-index
- 110
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology64%
- Medicine22.8%
- Immunology and Microbiology3.6%
- Computer Science2.6%
- Neuroscience1.8%
- Engineering1.3%
- Other3.9%
Topics
- CRISPR and Genetic Engineering3.9%
- Cell Image Analysis Techniques3.4%
- RNA Research and Splicing2.5%
- RNA modifications and cancer2.2%
- DNA Repair Mechanisms2.1%
- RNA and protein synthesis mechanisms2.1%
- Other83.8%
Coauthors
- Kevin R. Brown35
- Amy H.Y. Tong16
- Katherine Chan16
- Brenda Andrews15
- Charles Boone13
- Michael Aregger12
- Nicholas Mikolajewicz12
- Chad L. Myers11
- Maximilian Billmann11
- Patricia Mero11
- Sachdev S. Sidhu11
- Traver Hart11
- Troy Ketela11
- Anne‐Claude Gingras10
- Chitra Venugopal10
- Hong Han10
- Sheila K. Singh10
- Andrea Habsid9
- Barbara Mair9
- Benjamin J. Blencowe9
- Chirayu Chokshi8
- Jeffrey L. Wrana8
- Michael Costanzo8
- Nazanin Tatari8
All papers
- CellProfiler: image analysis software for identifying and quantifying cell phenotypes
Authors: Anne E. Carpenter, Thouis R. Jones, Michael R. Lamprecht, Colin Clarke, In Han Kang, Ola Friman, David A. Guertin, Joo Han Chang, Robert A. Lindquist, Jason Moffat, Polina Golland, David M. Sabatini - Genome biology 2006 cited by 5,483
- High-content CRISPR screening
Authors: Christoph Bock, Paul Datlinger, Florence M. Chardon, Matthew A. Coelho, Matthew B. Dong, Keith A. Lawson, Tian Lu, Laetitia Maroc, Thomas M. Norman, Bicna Song, Geoff Stanley, Sidi Chen, Mathew J. Garnett, Wei Li, Jason Moffat, Lei S. Qi, Rebecca S. Shapiro, Jay Shendure, Jonathan S. Weissman, Xiaowei Zhuang - Nature Reviews Methods Primers 2022 cited by 574
- High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
Authors: Traver Hart, Megha Chandrashekhar, Michael Aregger, Zachary Steinhart, Kevin R. Brown, Graham MacLeod, Monika Mis, Michal Zimmermann, Amélie Fradet‐Turcotte, Song Sun, Patricia Mero, Peter B. Dirks, Sachdev S. Sidhu, Frederick P. Roth, Olivia S. Rissland, Daniel Durocher, Stéphane Angers, Jason Moffat - Cell 2015 cited by 1,824
- Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy
Authors: Sumaiyah K. Rehman, Jennifer Haynes, Évelyne Collignon, Kevin R. Brown, Yadong Wang, Allison M.L. Nixon, Jeffrey P. Bruce, Jeffrey A. Wintersinger, Arvind Singh Mer, Edwyn B.L. Lo, Cherry Leung, Evelyne Lima‐Fernandes, Nicholas Pedley, Fraser Soares, Sophie McGibbon, Housheng Hansen He, Aaron Pollet, Trevor J. Pugh, Benjamin Haibe‐Kains, Quaid Morris, Miguel Ramalho‐Santos, Sidhartha Goyal, Jason Moffat, Catherine O′Brien - Cell 2021 cited by 509
- Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
Authors: Traver Hart, Amy H.Y. Tong, Katie Chan, Jolanda van Leeuwen, Ashwin Seetharaman, Michael Aregger, Megha Chandrashekhar, Nicole Hustedt, Sahil Seth, Avery J. C. Noonan, Andrea Habsid, Olga Sizova, L. Nedyalkova, Ryan Climie, Leanne Tworzyanski, Keith A. Lawson, Maria A. Sartori, Sabriyeh Alibeh, David Tieu, Sanna N. Masud, Patricia Mero, Alexander Weiß, Kevin R. Brown, Matej Ušaj, Maximilian Billmann, Mahfuzur Rahman, Michael Costanzo, Chad L. Myers, Brenda Andrews, Charles Boone, Daniel Durocher, Jason Moffat - G3 Genes Genomes Genetics 2017 cited by 681
- Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Authors: Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Víctor R. De Jesús, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah L. Fordyce Martin, Qian Huang, Elizabeth Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Li Ren, Amy H.Y. Tong, Michael Aregger, Katherine Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary D. Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat - Nature 2020 cited by 479
- The shieldin complex mediates 53BP1-dependent DNA repair
Authors: Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J. Pettitt, Alexanda K. Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann, Stefano Annunziato, Dragomir B. Krastev, Feifei Song, Inger Brandsma, Jessica Frankum, Rachel Brough, Alana Sherker, Sébastien Landry, Rachel K. Szilard, Meagan Munro, Andrea McEwan, Théo Goullet de Rugy, Zhen‐Yuan Lin, Traver Hart, Jason Moffat, Anne‐Claude Gingras, Alberto Martín, Haico van Attikum, Jos Jonkers, Christopher J. Lord, Sven Rottenberg, Daniel Durocher - Nature 2018 cited by 675
- A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen
Authors: Jason Moffat, Dorre A. Grueneberg, Xiaoping Yang, So Young Kim, Angela M. Kloepfer, Gregory Hinkle, Bruno Piqani, Thomas Eisenhaure, Biao Luo, Jennifer K. Grenier, Anne E. Carpenter, Shi Yin Foo, Sheila A. Stewart, Brent R. Stockwell, Nir Hacohen, William C. Hahn, Eric S. Lander, David M. Sabatini, David E. Root - Cell 2006 cited by 1,872
- Identifying chemogenetic interactions from CRISPR screens with drugZ
Authors: Medina Colic, Gang Wang, Michal Zimmermann, Keith Mascall, Megan McLaughlin, Lori L. Bertolet, Walter F. Lenoir, Jason Moffat, Stéphane Angers, Daniel Durocher, Traver Hart - Genome Medicine 2019 cited by 235
- Context-dependent regulation of ferroptosis sensitivity
Authors: Leslie Magtanong, Grace D. Mueller, Kevin J. Williams, Maximilian Billmann, Katherine Chan, David A. Armenta, Lauren E. Pope, Jason Moffat, Charles Boone, Chad L. Myers, James A. Olzmann, Steven J. Bensinger, Scott J. Dixon - Cell chemical biology 2022 cited by 116
- Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia
Authors: Alicia M. Cole, Zezhou Wang, Étienne Coyaud, Véronique Voisin, Marcela Gronda, Yulia Jitkova, Rachel Mattson, Rose Hurren, Sonja Babovic, Neil MacLean, Ian J. Restall, Xiaoming Wang, Danny V. Jeyaraju, Mahadeo A. Sukhai, Swayam Prabha, Shaheena Bashir, Ashwin Ramakrishnan, Elisa Leung, Yi Hua Qia, Nianxian Zhang, Kevin R. Combes, Troy Ketela, Fengshu Lin, Walid A. Houry, Ahmed Aman, Rima Al‐awar, Wei Zheng, Erno Wienholds, Chang Xu, John E. Dick, Jean Wang, Jason Moffat, Mark D. Minden, Connie J. Eaves, Gary D. Bader, Zhenyue Hao, Steven M. Kornblau, Brian Raught, Aaron D. Schimmer - Cancer Cell 2015 cited by 349
- Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma
Authors: Maleeha Qazi, Parvez Vora, Chitra Venugopal, Sachdev S. Sidhu, Jason Moffat, Charles Swanton, Sheila K. Singh - Annals of Oncology 2017 cited by 401
- Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
Authors: Marko Škrtić, Shrivani Sriskanthadevan, Bozhena Jhas, Marinella Gebbia, Xiaoming Wang, Zezhou Wang, Rose Hurren, Yulia Jitkova, Marcela Gronda, Neil MacLean, Courteney K. Lai, Yanina Eberhard, Justyna Bartoszko, Paul A. Spagnuolo, Angela C. Rutledge, Alessandro Datti, Troy Ketela, Jason Moffat, Brian H. Robinson, Jessie Cameron, Jeffery L. Wrana, Connie J. Eaves, Mark D. Minden, Jean Wang, John E. Dick, R. Keith Humphries, Corey Nislow, Guri Giaever, Aaron D. Schimmer - Cancer Cell 2011 cited by 694
- Identifying cell receptors for the nanoparticle protein corona using genome screens
Authors: Wayne Ngo, Jamie L. Y. Wu, Zachary P. Lin, Yuwei Zhang, Bram Bussin, Adrian Granda Farias, Abdullah M. Syed, Katherine Chan, Andrea Habsid, Jason Moffat, Warren C. W. Chan - Nature Chemical Biology 2022 cited by 91
- Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1
Authors: David A. Guertin, Deanna M. Stevens, Carson C. Thoreen, Aurora A. Burds, Nada Y. Kalaany, Jason Moffat, Michael Brown, Kevin Fitzgerald, David M. Sabatini - Developmental Cell 2006 cited by 1,405
- A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
Authors: Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D.R. Knight, Zhen‐Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne‐Claude Gingras, Brian Raught, Laurence Pelletier - Cell 2015 cited by 575
- The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma
Authors: Parvez Vora, Chitra Venugopal, Sabra K. Salim, Nazanin Tatari, David Bakhshinyan, Mohini Singh, Mathieu Seyfrid, Deepak Upreti, Stefan Rentas, Nicholas Wong, Rashida Williams, Maleeha Qazi, Chirayu Chokshi, Avrilynn Ding, Minomi Subapanditha, Neil Savage, Sujeivan Mahendram, Emily S. Ford, Ashley Adile, Dillon McKenna, Nicole McFarlane, Vince Huynh, Ryan G. Wylie, James Pan, Jonathan L. Bramson, Kristin J. Hope, Jason Moffat, Sheila K. Singh - Cell stem cell 2020 cited by 187
- CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
Authors: Michal Zimmermann, Olga Murina, Martin A.M. Reijns, Angelo Agathanggelou, Rachel Challis, Žygimantė Tarnauskaitė, Morwenna Muir, Adeline Fluteau, Michael Aregger, Andrea McEwan, Wei Yuan, Matthew Clarke, Maryou B. Lambros, Shankara Paneesha, Paul Moss, Megha Chandrashekhar, Stéphane Angers, Jason Moffat, Valerie G. Brunton, Traver Hart, Johann S. de Bono, Tatjana Stanković, Andrew P. Jackson, Daniel Durocher - Nature 2018 cited by 418
- Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer
Authors: Chewei Anderson Chang, Jayu Jen, Shaowen Jiang, Azin Sayad, Arvind Singh Mer, Kevin R. Brown, Allison M.L. Nixon, Avantika Dhabaria, Kwan Ho Tang, David Venet, Christos Sotiriou, Jiehui Deng, Kwok-kin Wong, Sylvia Adams, Peter Meyn, Adriana Heguy, Jane A. Skok, Aristotelis Tsirigos, Beatrix Ueberheide, Jason Moffat, Abhyudai Singh, Benjamin Haibe-Kains, Alireza Khodadadi-Jamayran, Benjamin G. Neel - Cancer Discovery 2021 cited by 112
- Measuring error rates in genomic perturbation screens: gold standards for human functional genomics
Authors: Traver Hart, Kevin R. Brown, Fabrice Sircoulomb, Robert Rottapel, Jason Moffat - Molecular Systems Biology 2014 cited by 464
- BAGEL: a computational framework for identifying essential genes from pooled library screens
Authors: G. Traver Hart, Jason Moffat - BMC Bioinformatics, BMC Bioinform. 2015 cited by 325
- A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening
Authors: Jouhyun Jeon, Satra Nim, Joan Teyra, Alessandro Datti, Jeffrey L. Wrana, Sachdev S. Sidhu, Jason Moffat, Philip M. Kim - Genome Medicine 2014 cited by 166
- Global Genetic Networks and the Genotype-to-Phenotype Relationship
Authors: Michael Costanzo, Elena Kuzmin, Jolanda van Leeuwen, Barbara Mair, Jason Moffat, Charles Boone, Brenda Andrews - Cell 2019 cited by 265
- A cohesin traffic pattern genetically linked to gene regulation
Authors: Anne-Laure Valton, Sergey V. Venev, Barbara Mair, Eraj Shafiq Khokhar, Amy H.Y. Tong, Matej Ušaj, Katherine Chan, Athma A. Pai, Jason Moffat, Job Dekker - Nature Structural & Molecular Biology 2022 cited by 86
