David A. Guertin
Active 2000–2025
- 50
- Papers
- 27,356
- Citations
- 41
- h-index
- 48
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology56.5%
- Medicine30.7%
- Immunology and Microbiology4.1%
- Neuroscience3%
- Computer Science1.9%
- Agricultural and Biological Sciences1%
- Other2.8%
Topics
- PI3K/AKT/mTOR signaling in cancer7.5%
- Cell Image Analysis Techniques3.3%
- Adipose Tissue and Metabolism2.9%
- Autophagy in Disease and Therapy2%
- Metabolism, Diabetes, and Cancer2%
- Cancer, Hypoxia, and Metabolism1.9%
- Other80.4%
Coauthors
- Joan Sánchez-Gurmaches13
- David M. Sabatini12
- Huawei Li11
- Camila Martínez Calejman10
- Yuefeng Tang8
- Wen‐Yu Hsiao7
- Chien‐Min Hung6
- Christian M. Metallo6
- Su Myung Jung6
- Kathryn E. Wellen5
- Martina Wallace5
- Amelia K. Luciano4
- Dannel McCollum4
- Jessica B. Spinelli4
- John D. Haley4
- Anne E. Carpenter3
- Cholsoon Jang3
- Cynthia A. Sparks3
- Jivani M. Gengatharan3
- Nathaniel W. Snyder3
- Qingbo Chen3
- Sophie Trefely3
- Amy J. Wagers2
- AnnMarie Torres2
All papers
- CellProfiler: image analysis software for identifying and quantifying cell phenotypes
Authors: Anne E. Carpenter, Thouis R. Jones, Michael R. Lamprecht, Colin Clarke, In Han Kang, Ola Friman, David A. Guertin, Joo Han Chang, Robert A. Lindquist, Jason Moffat, Polina Golland, David M. Sabatini - Genome biology 2006 cited by 5,483
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
Authors: Dos D. Sarbassov, David A. Guertin, Siraj M. Ali, David M. Sabatini - Science 2005 cited by 6,217
- Acetyl-CoA metabolism in cancer
Authors: David A. Guertin, Kathryn E. Wellen - Nature reviews. Cancer 2023 cited by 280
- mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
Authors: Timothy R. Peterson, Shomit Sengupta, Thurl E. Harris, Anne E. Carmack, Seong A. Kang, Eric Balderas, David A. Guertin, Katherine L. Madden, Anne E. Carpenter, Brian N. Finck, David M. Sabatini - Cell 2011 cited by 1,219
- Spatiotemporal structure of cell fate decisions in murine neural crest
Authors: Ruslan Soldatov, Markéta Kaucká, Maria Eleni Kastriti, Julian Petersen, Tatiana Chontorotzea, Lukas Englmaier, Natalia Akkuratova, Yunshi Yang, Martin Häring, Vyacheslav Dyachuk, Christoph Bock, Matthias Farlik, Michael L. Piacentino, Franck Boismoreau, Markus M. Hilscher, Chika Yokota, Xiaoyan Qian, Mats Nilsson, Marianne Bronner‐Fraser, Laura Croci, Wen-Yu Hsiao, David A. Guertin, Jean‐François Brunet, G. Giacomo Consalez, Patrik Ernfors, Kaj Fried, Peter V. Kharchenko, Igor Adameyko - Science 2019 cited by 573
- Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton
Authors: Dos D. Sarbassov, Siraj M. Ali, Do‐Hyung Kim, David A. Guertin, Robert Latek, Hediye Erdjument‐Bromage, Paul Tempst, David M. Sabatini - Current Biology 2004 cited by 2,658
- Defining the Role of mTOR in Cancer
Authors: David A. Guertin, David M. Sabatini - Cancer Cell 2007 cited by 2,812
- Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1
Authors: David A. Guertin, Deanna M. Stevens, Carson C. Thoreen, Aurora A. Burds, Nada Y. Kalaany, Jason Moffat, Michael Brown, Kevin Fitzgerald, David M. Sabatini - Developmental Cell 2006 cited by 1,405
- T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming
Authors: Kai Yang, Sharad Shrestha, Hu Zeng, Peer W. F. Karmaus, Geoffrey Neale, Peter Vogel, David A. Guertin, Richard F. Lamb, Hongbo Chi - Immunity 2013 cited by 388
- Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed
Authors: Joan Sánchez-Gurmaches, David A. Guertin - Nature Communications 2014 cited by 360
- Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues
Authors: Martina Wallace, Courtney R. Green, Lindsay S. Roberts, Yujung Michelle Lee, Justin L. McCarville, Joan Sánchez-Gurmaches, Noah Meurs, Jivani M. Gengatharan, Justin D. Hover, Susan A. Phillips, Theodore P. Ciaraldi, David A. Guertin, Pedro Cabrales, Janelle S. Ayres, Daniel K. Nomura, Rohit Loomba, Christian M. Metallo - Nature Chemical Biology 2018 cited by 221
- mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis
Authors: Camila Martínez Calejman, Sophie Trefely, S. W. Entwisle, Amelia K. Luciano, Sunmi Jung, Wen‐Yu Hsiao, AnnMarie Torres, C. M. Hung, H. Li, Nathaniel W. Snyder, Judit Villén, Kathryn E. Wellen, David A. Guertin - Nature Communications 2020 cited by 152
- Brown Adipose Tissue Development and Metabolism
Authors: Su Myung Jung, Joan Sánchez-Gurmaches, David A. Guertin - Handbook of experimental pharmacology 2018 cited by 134
- Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis
Authors: Grace Park, John A. Haley, Johnny Le, Su Myung Jung, Timothy P. Fitzgibbons, Ekaterina Korobkina, Huawei Li, Shelagh M. Fluharty, Qingbo Chen, Jessica B. Spinelli, Chinmay M. Trivedi, Cholsoon Jang, David A. Guertin - Nature Metabolism 2023 cited by 71
- Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females
Authors: Sully Fernandez, John M. Viola, AnnMarie Torres, Martina Wallace, Sophie Trefely, Steven Zhao, Hayley C. Affronti, Jivani M. Gengatharan, David A. Guertin, Nathaniel W. Snyder, Christian M. Metallo, Kathryn E. Wellen - Cell Reports 2019 cited by 76
- PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors
Authors: Joan Sánchez-Gurmaches, Chien‐Min Hung, Cynthia A. Sparks, Yuefeng Tang, Huawei Li, David A. Guertin - Cell Metabolism 2012 cited by 346
- mTOR-Dependent Cell Survival Mechanisms
Authors: Clarey Hung, Luisa García-Haro, Caroline A. Sparks, David A. Guertin - Cold Spring Harbor Perspectives in Biology 2012 cited by 204
- Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
Authors: Joan Sánchez-Gurmaches, Yuefeng Tang, Naja Zenius Jespersen, Martina Wallace, Camila Martínez Calejman, Sharvari Gujja, Huawei Li, Yvonne J. K. Edwards, Christian Wolfrum, Christian M. Metallo, Søren Nielsen, Camilla Schéele, David A. Guertin - Cell Metabolism 2017 cited by 206
- Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
Authors: Su Myung Jung, Chien‐Min Hung, Samuel Hildebrand, Joan Sánchez-Gurmaches, Bárbara Martínez-Pastor, Jivani M. Gengatharan, Martina Wallace, Dimpi Mukhopadhyay, Camila Martínez Calejman, Amelia K. Luciano, Wen‐Yu Hsiao, Yuefeng Tang, Huawei Li, Danette L. Daniels, Raúl Mostoslavsky, Christian M. Metallo, David A. Guertin - Molecular Cell 2019 cited by 82
- A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis
Authors: Qingbo Chen, Lei Huang, Dongning Pan, Kai Hu, Rui Li, Randall H. Friedline, Jason K. Kim, Lihua Julie Zhu, David A. Guertin, Yong‐Xu Wang - Nature Communications 2022 cited by 26
- Adipocyte lineages: Tracing back the origins of fat
Authors: Joan Sánchez-Gurmaches, David A. Guertin - Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013 cited by 252
- Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease
Authors: Peter L. Lee, Yuefeng Tang, Huawei Li, David A. Guertin - Molecular Metabolism 2016 cited by 122
- Highly Selective In Vivo Labeling of Subcutaneous White Adipocyte Precursors with Prx1-Cre
Authors: Joan Sánchez-Gurmaches, Wen‐Yu Hsiao, David A. Guertin - Stem Cell Reports 2015 cited by 112
- Integrating adipocyte insulin signaling and metabolism in the multi-omics era
Authors: Camila Martínez Calejman, Will Doxsey, Daniel J. Fazakerley, David A. Guertin - Trends in Biochemical Sciences 2022 cited by 47
