Christoph Bock
Active 1992–2026
- 212
- Papers
- 43,061
- Citations
- 108
- h-index
- 197
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University1.1%
- Inserm0.8%
- Heidelberg University0.6%
- Broad Institute0.6%
- Centre National de la Recherche Scientifique0.5%
- Stanford University0.5%
- Other95.9%
Fields
- Biochemistry, Genetics and Molecular Biology52.3%
- Medicine31.3%
- Immunology and Microbiology8.5%
- Neuroscience3%
- Agricultural and Biological Sciences1.1%
- Engineering0.8%
- Other3%
Topics
- Epigenetics and DNA Methylation8.4%
- Single-cell and spatial transcriptomics3.5%
- Genomics and Chromatin Dynamics2.8%
- RNA modifications and cancer2.6%
- Cancer Genomics and Diagnostics2.2%
- CRISPR and Genetic Engineering2.1%
- Other78.4%
Coauthors
- Thomas Krausgruber40
- Matthias Farlik28
- André F. Rendeiro21
- Michael Schuster19
- Alexander Meissner18
- Nikolaus Fortelny18
- Thomas Lengauer18
- Thomas Penz17
- Hongcang Gu15
- Christian Schmidl14
- Paul Datlinger14
- Florian Halbritter13
- Stefan Kubicek13
- Johanna Klughammer11
- Fabian Müller10
- Jörn Walter10
- Nathan C. Sheffield10
- Andreas Gnirke9
- Daniele Barreca9
- Róbert Královics9
- Andreas Bergthaler8
- Hendrik G. Stunnenberg8
- Amelie Nemc7
- Andreas Schönegger7
All papers
- Pooled CRISPR screening with single-cell transcriptome readout
Authors: Paul Datlinger, André F. Rendeiro, Christian Schmidl, Thomas Krausgruber, Peter Traxler, Johanna Klughammer, Linda C. Schuster, Amelie Kuchler, Donát Alpár, Christoph Bock - Nature Methods 2017 cited by 1,145
- Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion
Authors: Yi-Ru Yu, Hana Imrichová, Haiping Wang, Tung Chao, Zhengtao Xiao, Min Gao, Marcela Rincón-Restrepo, Fabien Franco, Raphaël Genolet, Wan-Chen Cheng, Camilla Jandus, George Coukos, Yi-Fan Jiang, Jason W. Locasale, Alfred Zippelius, Pu-Ste Liu, Li Tang, Christoph Bock, Nicola Vannini, Ping‐Chih Ho - Nature Immunology 2020 cited by 569
- High-content CRISPR screening
Authors: Christoph Bock, Paul Datlinger, Florence M. Chardon, Matthew A. Coelho, Matthew B. Dong, Keith A. Lawson, Tian Lu, Laetitia Maroc, Thomas M. Norman, Bicna Song, Geoff Stanley, Sidi Chen, Mathew J. Garnett, Wei Li, Jason Moffat, Lei S. Qi, Rebecca S. Shapiro, Jay Shendure, Jonathan S. Weissman, Xiaowei Zhuang - Nature Reviews Methods Primers 2022 cited by 574
- Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells
Authors: Elizabeth C. Rosser, Christopher Piper, Diana E. Matei, Paul A. Blair, André F. Rendeiro, Michael Orford, Dagmar Alber, Thomas Krausgruber, Diego Catalán, Nigel Klein, Jessica Manson, Ignat Drozdov, Christoph Bock, Lucy R. Wedderburn, Simon Eaton, Claudia Mauri - Cell Metabolism 2020 cited by 562
- Glioma progression is shaped by genetic evolution and microenvironment interactions
Authors: Frederick S. Varn, Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling, Lee Cooper, Tathiane M. Malta, Taylor Wade, Thaís S. Sabedot, Daniel J. Brat, Peter V. Gould, Adelheid Wöehrer, Kenneth Aldape, Azzam Ismail, Santhosh Sivajothi, Floris P Barthel, Hoon Kim, Emre Kocakavuk, Nazia Ahmed, Kieron White, Indrani Datta, Hyo-Eun Moon, Steven Pollock, Christine N. Goldfarb, Ga-Hyun Lee, Luciano Garofano, Kevin Anderson, Djamel Nehar-Belaid, Jill S. Barnholtz‐Sloan, Spyridon Bakas, Annette T. Byrne, Fulvio D’Angelo, Hui K. Gan, Mustafa Khasraw, Simona Migliozzi, D. Ryan Ormond, Sun Ha Paek, Erwin G. Van Meir, Annemiek Walenkamp, Colin Watts, Tobias Weiss, Michael Weller, Karolina Palucka, Lucy F. Stead, Laila Poisson, Houtan Noushmehr, Antonio Iavarone, Roel G.W. Verhaak, Frederick S. Varn, Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling, Lee Cooper, Tathiane M. Malta, Taylor Wade, Thaís S. Sabedot, Daniel J. Brat, Peter V. Gould, Adelheid Wöehrer, Kenneth Aldape, Azzam Ismail, Santhosh Sivajothi, Floris P Barthel, Hoon Kim, Emre Kocakavuk, Nazia Ahmed, Kieron White, Indrani Datta, Hyo-Eun Moon, Steven Pollock, Christine N. Goldfarb, Ga-Hyun Lee, Luciano Garofano, Kevin Anderson, Djamel Nehar-Belaid, Jill S. Barnholtz‐Sloan, Spyridon Bakas, Annette T. Byrne, Fulvio D’Angelo, Hui K. Gan, Mustafa Khasraw, Simona Migliozzi, D. Ryan Ormond, Sun Ha Paek, Erwin G. Van Meir, Annemiek Walenkamp, Colin Watts, Tobias Weiss, Michael Weller, Kristin Alfaro-Munoz, Samirkumar B. Amin, David M. Ashley, Christoph Bock, Andrew Brodbelt, Ketan R. Bulsara, Ana Valéria Castro, Jennifer Connelly and 47 more - Cell 2022 cited by 519
- The pathophysiology of sepsis and precision-medicine-based immunotherapy
Authors: Evangelos J. Giamarellos‐Bourboulis, Anna C. Aschenbrenner, Michael Bauer, Christoph Bock, Thierry Calandra, Irit Gat‐Viks, Evdoxia Kyriazopoulou, Mihaela Lupșe, Guillaume Monneret, Peter Pickkers, Joachim L. Schultze, Tom van der Poll, Frank L. van de Veerdonk, Alexander P. J. Vlaar, Sebastian Weis, W. Joost Wiersinga, Mihai G. Netea - Nature Immunology 2024 cited by 323
- Specification of tissue-resident macrophages during organogenesis
Authors: Elvira Mass, Iván Ballesteros, Matthias Farlik, Florian Halbritter, Patrick Günther, Lucile Crozet, Christian E. Jacome-Galarza, Kristian Händler, Johanna Klughammer, Yasuhiro Kobayashi, Elisa Gomez Perdiguero, Joachim L. Schultze, Marc Beyer, Christoph Bock, Frédéric Geissmann - Science 2016 cited by 893
- Longitudinal molecular trajectories of diffuse glioma in adults
Authors: Floris P Barthel, Kevin C. Johnson, Frederick S. Varn, Anzhela D. Moskalik, Georgette Tanner, Emre Kocakavuk, Kevin Anderson, Olajide Abiola, Kenneth Aldape, Kristin Alfaro-Munoz, Donát Alpár, Samirkumar B. Amin, David M. Ashley, Pratiti Bandopadhayay, Jill S. Barnholtz‐Sloan, Rameen Beroukhim, Christoph Bock, Priscilla K. Brastianos, Daniel J. Brat, Andrew Brodbelt, Alexander Bruns, Ketan R. Bulsara, Aruna Chakrabarty, Arnab Chakravarti, Jeffrey H. Chuang, Elizabeth B. Claus, Elizabeth J. Cochran, Jennifer Connelly, J Costello, Gaetano Finocchiaro, Michael Fletcher, Pim J. French, Hui K. Gan, Mark R. Gilbert, Peter V. Gould, Matthew Grimmer, Antonio Iavarone, Azzam Ismail, Michael D. Jenkinson, Mustafa Khasraw, Hoon Kim, Mathilde C. M. Kouwenhoven, Peter S. LaViolette, Meihong Li, Peter Lichter, Keith L. Ligon, Allison K. Lowman, Tathiane M. Malta, Tali Mazor, Kerrie L. McDonald, Annette M. Molinaro, Do-Hyun Nam, Naema Nayyar, Ho‐Keung Ng, Chew Yee Ngan, Simone P. Niclou, Johanna M. Niers, Houtan Noushmehr, Javad Noorbakhsh, D. Ryan Ormond, Chul‐Kee Park, Laila Poisson, Raúl Rabadán, Bernhard Radlwimmer, Ganesh Rao, Guido Reifenberger, K. Jason, Michael Schuster, Brian Shaw, Susan Short, Peter A. Sillevis Smitt, Andrew E. Sloan, Marion Smits, Hiromichi Suzuki, Ghazaleh Tabatabai, Erwin G. Van Meir, Colin Watts, Michael Weller, Pieter Wesseling, Bart A. Westerman, Georg Widhalm, Adelheid Woehrer, W. K. Alfred Yung, Gelareh Zadeh, Jason T. Huse, John de Groot, Lucy F. Stead, Roel G.W. Verhaak, Floris P Barthel, Kevin C. Johnson, Frederick S. Varn, Anzhela D. Moskalik, Georgette Tanner, Emre Kocakavuk, Kevin J. Anderson, Kenneth Aldape, Kristin Alfaro-Munoz, Samirkumar B. Amin, David M. Ashley, Pratiti Bandopadhayay and 63 more - Nature, Nat. 2019 cited by 609
- Rational discovery of molecular glue degraders via scalable chemical profiling
Authors: Cristina Mayor‐Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton I. Siklos, Hana Imrichová, Ines H. Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C. Müller, Johannes Zuber, Matthias Geyer, Nicolas H. Thomä, Stefan Kubicek, Georg E. Winter - Nature Chemical Biology 2020 cited by 359
- Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis
Authors: Laurienne Edgar, Naveed Akbar, Adam Braithwaite, Thomas Krausgruber, Héctor Gallart‐Ayala, Jade Bailey, Alastair Corbin, Tariq Khoyratty, Joshua T. Chai, Mohammad Alkhalil, André F. Rendeiro, Klemen Žiberna, Ritu Arya, Thomas J. Cahill, Christoph Bock, Jurga Laurencikiene, Mark J. Crabtree, Madeleine E. Lemieux, Niels P. Riksen, Mihai G. Netea, Craig E. Wheelock, Keith M. Channon, Mikael Rydén, Irina A. Udalova, Ricardo Carnicer, Robin P. Choudhury - Circulation 2021 cited by 308
- Structural cells are key regulators of organ-specific immune responses
Authors: Thomas Krausgruber, Nikolaus Fortelny, Victoria Fife, Martin Senekowitsch, Linda C. Schuster, Alexander Lercher, Amelie Nemc, Christian Schmidl, André F. Rendeiro, Andreas Bergthaler, Christoph Bock - Nature, Nat. 2020 cited by 440
- B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma
Authors: Johannes Griss, Wolfgang Bauer, Christine Wagner, Martín Simón, Minyi Chen, Katharina Grabmeier‐Pfistershammer, Margarita Maurer‐Granofszky, Florian Roka, Thomas Penz, Christoph Bock, Gao Zhang, Meenhard Herlyn, Katharina Glatz, Heinz Läubli, Kirsten D. Mertz, Peter Petzelbauer, Thomas Wiesner, Markus Hartl, Winfried F. Pickl, Rajasekharan Somasundaram, Peter Steinberger, Stephan N. Wagner - Nature Communications 2019 cited by 380
- Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal
Authors: Deqiang Sun, Min Luo, Mira Jeong, Blanca Rodríguez, Zheng Xia, Rebecca Hannah, Hui Wang, Thuc T. Le, Kym F. Faull, Rui Chen, Hongcang Gu, Christoph Bock, Alexander Meissner, Berthold Göttgens, Gretchen J. Darlington, Wei Li, Margaret A. Goodell - Cell stem cell 2014 cited by 691
- Spatiotemporal structure of cell fate decisions in murine neural crest
Authors: Ruslan Soldatov, Markéta Kaucká, Maria Eleni Kastriti, Julian Petersen, Tatiana Chontorotzea, Lukas Englmaier, Natalia Akkuratova, Yunshi Yang, Martin Häring, Vyacheslav Dyachuk, Christoph Bock, Matthias Farlik, Michael L. Piacentino, Franck Boismoreau, Markus M. Hilscher, Chika Yokota, Xiaoyan Qian, Mats Nilsson, Marianne Bronner‐Fraser, Laura Croci, Wen-Yu Hsiao, David A. Guertin, Jean‐François Brunet, G. Giacomo Consalez, Patrik Ernfors, Kaj Fried, Peter V. Kharchenko, Igor Adameyko - Science 2019 cited by 573
- Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells
Authors: Florian Puhm, Taras Afonyushkin, Ulrike Resch, Georg Obermayer, Manfred Rohde, T. Penz, Michael Schuster, Gabriel Wagner, André F. Rendeiro, Imène Melki, Christoph Kaun, Johann Wojta, Christoph Bock, Bernd Jilma, Nigel Mackman, Éric Boilard, Christoph J. Binder - Circulation Research 2019 cited by 306
- Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection
Authors: Peter Ulz, Samantha Perakis, Qing Zhou, Tina Moser, Jelena Belic, Isaac Lazzeri, Albert Wölfler, Armin Zebisch, Armin Gerger, Gunda Pristauz, Edgar Petru, Brandon White, Charles E. S. Roberts, John St. John, Michael G. Schimek, Jochen B. Geigl, Thomas Bauernhofer, Heinz Sill, Christoph Bock, Ellen Heitzer, Michael R. Speicher - Nature Communications 2019 cited by 275
- Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF
Authors: Michael Delacher, Charles D. Imbusch, Agnes Hotz‐Wagenblatt, Jan‐Philipp Mallm, Katharina Bauer, Malte Simon, Dania Riegel, André F. Rendeiro, Sebastian Bittner, Lieke Sanderink, Asmita Pant, Lisa Schmidleithner, Kathrin Luise Braband, Bernd Echtenachter, Alexander Fischer, Valentina Giunchiglia, Petra Hoffmann, Matthias Edinger, Christoph Bock, Michael Rehli, Benedikt Brors, Christian Schmidl, Markus Feuerer - Immunity 2020 cited by 270
- Dnmt3a is essential for hematopoietic stem cell differentiation
Authors: Grant A. Challen, Deqiang Sun, Mira Jeong, Min Luo, Jaroslav Jelı́nek, Jonathan S. Berg, Christoph Bock, Aparna Vasanthakumar, Hongcang Gu, Yuanxin Xi, Shoudan Liang, Yue Lu, Gretchen J. Darlington, Alexander Meissner, Jean‐Pierre J. Issa, Lucy A. Godley, Wei Li, Margaret A. Goodell - Nature Genetics 2011 cited by 1,107
- Toward understanding and exploiting tumor heterogeneity
Authors: Ash A. Alizadeh, Victoria Aranda, Alberto Bardelli, Cédric Blanpain, Christoph Bock, Christine Borowski, Carlos Caldas, Andrea Califano, Michael Doherty, Markus Elsner, Manel Esteller, Rebecca C. Fitzgerald, Jan O. Korbel, Peter Lichter, Christopher E. Mason, Nicholas E. Navin, Dana Pe’er, Kornélia Polyák, Charles W.M. Roberts, Lillian L. Siu, Alexandra Snyder, Hannah Stower, Charles Swanton, Roel G.W. Verhaak, Jean C. Zenklusen, Johannes Zuber, Jessica Zucman‐Rossi - Nature Medicine 2015 cited by 769
- Ultra-high-throughput single-cell RNA sequencing and perturbation screening with combinatorial fluidic indexing
Authors: Paul Datlinger, André F. Rendeiro, Thorina Boenke, Martin Senekowitsch, Thomas Krausgruber, Daniele Barreca, Christoph Bock - Nature Methods 2021 cited by 272
- Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes
Authors: Roman A. Romanov, Amit Zeisel, Joanne Bakker, Fatima Girach, Arash Hellysaz, Raju Tomer, Alán Alpár, Jan Mulder, Frédéric Clotman, Erik Keimpema, Brian Hsueh, Ailey Crow, Henrik Martens, Christian Schwindling, Daniela Calvigioni, Jaideep S. Bains, Zoltán Máté, Gábor Szabó, Yuchio Yanagawa, Mingdong Zhang, André F. Rendeiro, Matthias Farlik, Mathias Uhlén, Peer Wulff, Christoph Bock, Christian Broberger, Karl Deisseroth, Tomas Hökfelt, Sten Linnarsson, Tamás L. Horváth, Tibor Harkany - Nature Neuroscience 2016 cited by 534
- Persistence of mature dendritic cells, T H 2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade
Authors: Christine Bangert, Katharina Rindler, Thomas Krausgruber, Natalia Alkon, Felix M. Thaler, Harald Kurz, Tanya Ayub, Denis Demirtas, Nikolaus Fortelny, Vera Vorstandlechner, Wolfgang Bauer, Tamara Quint, Michael Mildner, Constanze Jonak, Adelheid Elbe‐Bürger, Johannes Griss, Christoph Bock, Patrick M. Brunner - Science Immunology 2021 cited by 182
- Single-cell transcriptomics combined with interstitial fluid proteomics defines cell type–specific immune regulation in atopic dermatitis
Authors: Thomas B. Rojahn, Vera Vorstandlechner, Thomas Krausgruber, Wolfgang Bauer, Natalia Alkon, Christine Bangert, Felix M. Thaler, Farzaneh Sadeghyar, Nikolaus Fortelny, Victoria Gernedl, Katharina Rindler, Adelheid Elbe‐Bürger, Christoph Bock, Michael Mildner, Patrick M. Brunner - Journal of Allergy and Clinical Immunology 2020 cited by 226
- ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors
Authors: Christian Schmidl, André F. Rendeiro, Nathan C. Sheffield, Christoph Bock - Nature Methods 2015 cited by 547
