Robert B. Darnell
Active 1993–2025
- 126
- Papers
- 38,259
- Citations
- 98
- h-index
- 125
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology65.6%
- Medicine16.8%
- Neuroscience9.8%
- Immunology and Microbiology3.5%
- Agricultural and Biological Sciences1.1%
- Veterinary0.7%
- Other2.5%
Topics
- RNA Research and Splicing9.7%
- RNA modifications and cancer9.5%
- RNA and protein synthesis mechanisms5.5%
- Genetics and Neurodevelopmental Disorders4.2%
- Cancer-related molecular mechanisms research3.9%
- MicroRNA in disease regulation3.2%
- Other64%
Coauthors
- John J. Fak29
- Jennifer C. Darnell19
- Aldo Mele18
- Christopher Y. Park12
- Chaolin Zhang11
- Hirotaka James Okano10
- Jernej Ule9
- Yuhki Saito9
- Caryn Hale8
- Kirk B. Jensen8
- Matteo Ruggiu8
- Mayu O. Frank8
- Donny D. Licatalosi7
- Ilana Zucker-Scharff7
- Kiran Musunuru7
- Michael J. Moore7
- Nathalie E. Blachère7
- Giovanni Stefani6
- Matthew L. Albert6
- Claire Fraser5
- Joseph M. Luna5
- Kirsty Sawicka5
- Yoko Tajima5
- Zhong Ru5
All papers
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
Authors: Jennifer C. Darnell, Sarah J. Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire Fraser, Elizabeth F. Stone, Cynthia Chen, John J. Fak, Sung Wook Chi, Donny D. Licatalosi, Joel D. Richter, Robert B. Darnell - Cell 2011 cited by 2,177
- A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
Authors: Shengdong Ke, Endalkachew A. Alemu, Claudia Mertens, Emily C. Gantman, John J. Fak, Aldo Mele, Bhagwattie Haripal, Ilana Zucker-Scharff, Michael J. Moore, Christopher Y. Park, Cathrine Broberg Vågbø, Anna Kusśnierczyk, Arne Klungland, James Darnell, Robert B. Darnell - Genes & Development 2015 cited by 834
- m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
Authors: Shengdong Ke, Amy Pandya‐Jones, Yuhki Saito, John J. Fak, Cathrine Broberg Vågbø, Shay Geula, Jacob H. Hanna, Douglas L. Black, James Darnell, Robert B. Darnell - Genes & Development 2017 cited by 575
- Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs
Authors: Kevin Hadi, Xiaotong Yao, Julie M. Behr, Aditya Deshpande, Charalampos Xanthopoulakis, Huasong Tian, Sarah Kudman, Joel Rosiene, Madison Darmofal, Joseph DeRose, Rick Mortensen, Emily M. Adney, Alon Shaiber, Zoran Gajic, Michael Sigouros, Kenneth Eng, Jeremiah A. Wala, Kazimierz O. Wrzeszczyński, Kanika Arora, Minita Shah, Anne-Katrin Emde, Vanessa Felice, Mayu O. Frank, Robert B. Darnell, Mahmoud Ghandi, Franklin W. Huang, Sally M. Dewhurst, John Maciejowski, Titia de Lange, Jeremy Setton, Nadeem Riaz, Jorge S. Reis‐Filho, Simon N. Powell, David A. Knowles, Ed Reznik, Bud Mishra, Rameen Beroukhim, Michael C. Zody, Nicolas Robine, Kenji Oman, Carissa A. Sanchez, Mary K. Kuhner, Lucian P. Smith, Patricia C. Galipeau, Thomas G. Paulson, Brian J. Reid, Xiaohong Li, David Wilkes, Andrea Sboner, Juan Miguel Mosquera, Olivier Elemento, Marcin Imieliński - Cell 2020 cited by 286
- A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ
Authors: Dylan Kwart, Andrew Gregg, Claudia Scheckel, Elisabeth A. Murphy, Dominik Paquet, Michael D. Duffield, John J. Fak, Olav Olsen, Robert B. Darnell, Marc Tessier‐Lavigne - Neuron 2019 cited by 332
- HITS-CLIP yields genome-wide insights into brain alternative RNA processing
Authors: Donny D. Licatalosi, Aldo Mele, John J. Fak, Jernej Ule, Melis Kayikci, Sung Wook, Tyson A. Clark, Anthony Schweitzer, John E. Blume, Xuning Wang, Jennifer C. Darnell, Robert B. Darnell - Nature 2008 cited by 1,418
- CLIP Identifies Nova-Regulated RNA Networks in the Brain
Authors: Jernej Ule, Kirk B. Jensen, Matteo Ruggiu, Aldo Mele, Aljaž Ule, Robert B. Darnell - Science 2003 cited by 1,138
- Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation
Authors: William Stephenson, Laura T. Donlin, Andrew Butler, Cristina Rozo, Bernadette Bracken, Ali Rashidfarrokhi, Susan M. Goodman, Lionel B. Ivashkiv, Vivian P. Bykerk, Dana E. Orange, Robert B. Darnell, Harold Swerdlow, Rahul Satija - Nature Communications 2018 cited by 369
- Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis
Authors: R. Camille Brewer, Tobias V. Lanz, Caryn Hale, Gregory D. Sepich‐Poore, Cameron Martino, Austin D. Swafford, Thomas S. Carroll, Sarah Kongpachith, Lisa K. Blum, Serra E. Elliott, Nathalie E. Blachère, Salina Parveen, John J. Fak, Vicky Yao, Olga G. Troyanskaya, Mayu O. Frank, Michelle S. Bloom, Shaghayegh Jahanbani, Alejandro M. Gomez, Radhika Iyer, Nitya S. Ramadoss, Orr Sharpe, Sangeetha Chandrasekaran, Lindsay B. Kelmenson, Qian Wang, Heidi Wong, Holly L. Torres, Mark Wiesen, Dana T. Graves, Kevin D. Deane, V. Michael Holers, Rob Knight, Robert B. Darnell, William H. Robinson, Dana E. Orange - Science Translational Medicine 2023 cited by 103
- Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps
Authors: Sung Wook, Julie B. Zang, Aldo Mele, Robert B. Darnell - Nature 2009 cited by 1,843
- Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk
Authors: Jian Zhou, Christopher Y. Park, Chandra L. Theesfeld, Aaron K. Wong, Yuan Yuan, Claudia Scheckel, John J. Fak, Julien Funk, Kevin Yao, Yoko Tajima, Alan Packer, Robert B. Darnell, Olga G. Troyanskaya - Nature Genetics 2019 cited by 328
- RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares
Authors: Dana E. Orange, Vicky Yao, Kirsty Sawicka, John J. Fak, Mayu O. Frank, Salina Parveen, Nathalie E. Blachère, Caryn Hale, Fan Zhang, Soumya Raychaudhuri, Olga G. Troyanskaya, Robert B. Darnell - New England Journal of Medicine 2020 cited by 203
- A call for transparent reporting to optimize the predictive value of preclinical research
Authors: Story C. Landis, Susan Amara, Khusru Asadullah, Chris Austin, Robi Blumenstein, Eileen W. Bradley, Ronald G. Crystal, Robert B. Darnell, Robert J. Ferrante, Howard Fillit, Robert Finkelstein, Marc Fisher, Howard E. Gendelman, Robert Golub, John L. Goudreau, Robert A. Gross, Amelie K. Gubitz, Sharon Hesterlee, David W. Howells, John R. Huguenard, Katrina L. Kelner, Walter J. Koroshetz, Dimitri Krainc, Stanley E. Lazic, Michael S. Levine, Malcolm Macleod, John M. McCall, Richard T. Moxley, Kalyani Narasimhan, Linda J. Noble‐Haeusslein, Steve Perrin, John D. Porter, Oswald Steward, Ellis F. Unger, Ursula Utz, Shai D. Silberberg - Nature 2012 cited by 1,224
- De Novo Gene Disruptions in Children on the Autistic Spectrum
Authors: Ivan Iossifov, Michael Ronemus, Dan Levy, Zihua Wang, Inessa Hakker, Julie Rosenbaum, Boris Yamrom, Yoonha Lee, Giuseppe Narzisi, Anthony Leotta, Jude Kendall, Ewa Grabowska, Beicong Ma, Steven C. Marks, Linda Rodgers, Asya Stepansky, Jennifer Troge, Peter Andrews, Mitchell A. Bekritsky, Kith Pradhan, Elena Ghiban, Melissa Kramer, Jennifer Parla, Ryan Demeter, Lucinda Fulton, Robert S. Fulton, Vincent Magrini, Kenny Ye, Jennifer C. Darnell, Robert B. Darnell, Elaine R. Mardis, Richard K. Wilson, Michael C. Schatz, W. Richard McCombie, Michael Wigler - Neuron 2012 cited by 1,515
- Genomic Patterns of De Novo Mutation in Simplex Autism
Authors: Tychele N. Turner, Bradley P. Coe, Diane E. Dickel, Kendra Hoekzema, Bradley J. Nelson, Michael C. Zody, Zev Kronenberg, Fereydoun Hormozdiari, Archana N. Raja, L Pennacchio, Robert B. Darnell, Evan E. Eichler - Cell 2017 cited by 376
- RNA processing and its regulation: global insights into biological networks
Authors: Donny D. Licatalosi, Robert B. Darnell - Nature Reviews Genetics 2009 cited by 795
- miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
Authors: Michael J. Moore, Troels K. H. Scheel, Joseph M. Luna, Christopher Y. Park, John J. Fak, Eiko Nishiuchi, Charles M. Rice, Robert B. Darnell - Nature Communications 2015 cited by 342
- Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction
Authors: Anh Tuân Phan, Vitaly Kuryavyi, Jennifer C. Darnell, Alexander Serganov, Ananya Majumdar, Serge Ilin, Tanya Raslin, Anna Polonskaia, Cynthia Chen, David J. Clain, Robert B. Darnell, Dinshaw J. Patel - Nature Structural & Molecular Biology 2011 cited by 256
- NOVA2 regulates neural circRNA biogenesis
Authors: David Knupp, Daphne Cooper, Yuhki Saito, Robert B. Darnell, Pedro Miura - Nucleic Acids Research 2021 cited by 83
- Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data
Authors: Dana E. Orange, Phaedra Agius, Edward F. DiCarlo, Nicolas Robine, Heather Geiger, Jackie Szymonifka, Michael McNamara, Ryan Cummings, Kathleen M. Andersen, Serene Z. Mirza, Mark P. Figgie, Lionel B. Ivashkiv, Alessandra B. Pernis, Caroline S. Jiang, Mayu O. Frank, Robert B. Darnell, Nithya Lingampali, William H. Robinson, Ellen M. Gravallese, the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus Network, Vivian P. Bykerk, Susan M. Goodman, Laura T. Donlin - Arthritis & Rheumatology 2018 cited by 214
- ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity
Authors: Michael J. Moore, Nathalie E. Blachère, John J. Fak, Christopher Y. Park, Kirsty Sawicka, Salina Parveen, Ilana Zucker-Scharff, Bruno Moltedo, Alexander Y. Rudensky, Robert B. Darnell - eLife 2018 cited by 165
- Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP
Authors: Nikita Vasilyev, Anna Polonskaia, Jennifer C. Darnell, Robert B. Darnell, Dinshaw J. Patel, Alexander Serganov - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 207
- Assembly and diploid architecture of an individual human genome via single-molecule technologies
Authors: Matthew Pendleton, Robert Sebra, Andy Wing Chun Pang, Ajay Ummat, Oscar Franzén, Tobias Rausch, Adrian M. Stütz, William Stedman, Thomas Anantharaman, Alex Hastie, Dai Heng, Markus Hsi-Yang Fritz, Han Cao, Ariella Cohain, Gintaras Deikus, R. Durrett, Scott C. Blanchard, Roger Altman, Chen-Shan Chin, Yan Guo, Ellen E. Paxinos, Jan O. Korbel, Robert B. Darnell, W. Richard McCombie, Pui–Yan Kwok, Christopher E. Mason, Eric E. Schadt, Ali Bashir - Nature Methods 2015 cited by 562
- FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory
Authors: Kirsty Sawicka, Caryn Hale, Christopher Y. Park, John J. Fak, Jodi Gresack, Sarah J. Van Driesche, Jin Joo Kang, Jennifer C. Darnell, Robert B. Darnell - eLife 2019 cited by 120
