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Robert I. Lechler

Active 1982–2023

126
Papers
24,524
Citations
89
h-index
126
i10-index

Citations

Citations per year for Robert I. Lechler1982: 2 citations1983: 10 citations1984: 6 citations1985: 6 citations1986: 10 citations1987: 12 citations1988: 13 citations1989: 23 citations1990: 33 citations1991: 10 citations1992: 22 citations1993: 28 citations1994: 21 citations1995: 12 citations1996: 28 citations1997: 27 citations1998: 53 citations1999: 70 citations2000: 93 citations2001: 146 citations2002: 164 citations2003: 248 citations2004: 272 citations2005: 250 citations2006: 238 citations2007: 268 citations2008: 310 citations2009: 237 citations2010: 248 citations2011: 235 citations2012: 206 citations2013: 196 citations2014: 185 citations2015: 171 citations2016: 168 citations2017: 180 citations2018: 184 citations2019: 506 citations2020: 606 citations2021: 622 citations2022: 525 citations2023: 347 citations2024: 455 citations2025: 209 citations2026: 2 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,290 citing papers, 29.8% of this breakdownUnited Kingdom: 789 citing papers, 10.3% of this breakdownChina: 609 citing papers, 7.9% of this breakdownGermany: 487 citing papers, 6.3% of this breakdownItaly: 334 citing papers, 4.3% of this breakdownFrance: 311 citing papers, 4.1% of this breakdownCanada: 273 citing papers, 3.6% of this breakdownNetherlands: 216 citing papers, 2.8% of this breakdownJapan: 203 citing papers, 2.6% of this breakdownAustralia: 202 citing papers, 2.6% of this breakdownSpain: 198 citing papers, 2.6% of this breakdownSwitzerland: 132 citing papers, 1.7% of this breakdown
0%29.8%Other 21.4%

Institutions

Fields

  • Medicine39.5%
  • Immunology and Microbiology33.8%
  • Biochemistry, Genetics and Molecular Biology13%
  • Neuroscience11.4%
  • Nursing0.6%
  • Engineering0.3%
  • Other1.4%

Topics

  • T-cell and B-cell Immunology10%
  • Immune Cell Function and Interaction9.7%
  • Immunotherapy and Immune Responses5.6%
  • Regulation of Appetite and Obesity4.4%
  • Adipokines, Inflammation, and Metabolic Diseases4%
  • Renal Transplantation Outcomes and Treatments2.9%
  • Other63.4%

Coauthors

All papers

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  1. Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials

    Authors: Birgit Sawitzki, Paul Harden, Petra Reinke, Aurélie Moreau, James A. Hutchinson, David Game, Qizhi Tang, Eva C. Guinan, Manuela Battaglia, William J. Burlingham, Ian S.D. Roberts, Mathias Streitz, Régis Josien, Carsten A. Böger, Cristiano Scottà, James F. Markmann, Joanna Hester, Karsten Juerchott, Cécile Braudeau, Ben James, Laura Contreras‐Ruiz, Jeroen B. van der Net, Tobias Bergler, Rossana Caldara, William Petchey, Matthias Edinger, Nathalie Dupas, Michael Kapinsky, Ingrid Mutzbauer, Natalie Otto, Robert Öllinger, María P. Hernández-Fuentes, Fadi Issa, Norbert Ahrens, Christoph Meyenberg, Sandra Karitzky, Ulrich Kunzendorf, Stuart J. Knechtle, Josep M. Grinyó, Peter J. Morris, L Brent, Andrew Bushell, Laurence A. Turka, Jeffrey A. Bluestone, Robert I. Lechler, Hans J. Schlitt, María Cristina Cuturi, Stephan Schlickeiser, Peter J. Friend, Tewfik Miloud, Alexander Scheffold, Antonio Secchi, Kerry Crisalli, Sang‐Mo Kang, Rachel Hilton, Bernhard Banas, Gilles Blancho, Hans‐Dieter Volk, Giovanna Lombardi, Kathryn J. Wood, Edward K. Geissler - The Lancet 2020 cited by 451

  2. Regulatory T cell-derived extracellular vesicles modify dendritic cell function

    Authors: Sim L. Tung, Dominic A. Boardman, Monica Sen, Marilena Letizia, Qi Peng, Nicole Cianci, Laura Dioni, Leo M. Carlin, Robert I. Lechler, Valentina Bollati, Giovanna Lombardi, Lesley A. Smyth - Scientific Reports 2018 cited by 236

  3. Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection

    Authors: D.A. Boardman, Christina Philippeos, Gilbert O. Fruhwirth, Mohammad A. A. Ibrahim, Rosalind Hannen, Dianne Cooper, Federica M. Marelli‐Berg, Fiona M. Watt, Robert I. Lechler, John Maher, L.A. Smyth, Giulia Lombardi - American Journal of Transplantation 2016 cited by 314

  4. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

    Authors: Graham M. Lord, Giuseppe Matarese, Jane K. Howard, Richard J. Baker, Stephen R. Bloom, Robert I. Lechler - Nature 1998 cited by 2,178

  5. CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+ T cells contributes to their regulatory function

    Authors: Lesley A. Smyth, Kulachelvy Ratnasothy, Julia Y. Tsang, Dominic Boardman, Alice Warley, Robert I. Lechler, Giovanna Lombardi - European Journal of Immunology 2013 cited by 263

  6. An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment

    Authors: Leena Halim, Marco Romano, Reuben McGregor, Isabel Corrêa, Polychronis Pavlidis, Nathali Grageda, Sec-Julie Hoong, Muhammed Yüksel, Wayel Jassem, Rosalind Hannen, Mark Ong, Olivia McKinney, Bu Hayee, Sophia N. Karagiannis, Nicholas Powell, Robert I. Lechler, Estefanía Nova‐Lamperti, Giovanna Lombardi - Cell Reports 2017 cited by 162

  7. Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation

    Authors: Alberto Sánchez‐Fueyo, Gavin Whitehouse, Nathali Grageda, Matthew Cramp, Tiong Yeng Lim, Marco Romano, Sarah Thirkell, Katie Lowe, Laura Fry, Julie Heward, A. Kerr, Jakia Ali, Chris Fisher, Gillian Lewis, Andrew Hope, Elisavet Kodela, Mike Lyne, Farzin Farzaneh, Shahram Kordasti, Irene Rebollo‐Mesa, Juan José Lozano, Niloufar Safinia, Nigel Heaton, Robert I. Lechler, Marc Martínez‐Llordella, Giovanna Lombardi - American Journal of Transplantation 2019 cited by 207

  8. Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells

    Authors: Pervinder Sagoo, Niwa Ali, Garima Garg, Frank O. Nestlé, Robert I. Lechler, Giovanna Lombardi - Science Translational Medicine 2011 cited by 375

  9. A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials

    Authors: Henrieta Fraser, Niloufar Safinia, Nathali Grageda, Sarah Thirkell, Katie Lowe, Laura Fry, Cristiano Scottà, Andrew Hope, Christopher Fisher, Rachel Hilton, David Game, Paul Harden, Andrew Bushell, Kathryn J. Wood, Robert I. Lechler, Giovanna Lombardi - Molecular Therapy — Methods & Clinical Development 2018 cited by 143

  10. Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells

    Authors: Marina Garín, Chung-Ching Chu, Déla Golshayan, Eva Cernuda‐Morollón, Robin Wait, Robert I. Lechler - Blood 2006 cited by 519

  11. Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients

    Authors: Paul Harden, David Game, Birgit Sawitzki, Jeroen B. van der Net, Joanna Hester, Andrew Bushell, Fadi Issa, Matthew O. Brook, Alaa Alzhrani, Stephan Schlickeiser, Cristiano Scottà, William Petchey, Mathias Streitz, Gilles Blancho, Quizhi Tang, James F. Markmann, Robert I. Lechler, Ian S.D. Roberts, Peter J. Friend, Rachel Hilton, Edward K. Geissler, Kathryn J. Wood, Giovanna Lombardi - American Journal of Transplantation 2020 cited by 126

  12. Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease

    Authors: Trishan Vaikunthanathan, Emmanuelle Landmann, Diana Marin Correa, Marco Romano, Silvia Cellone Trevelin, Qi Peng, Elena Crespo, Mauro Corrado, Juan José Lozano, Erika L. Pearce, Elena Perpiñán, Anna Zoccarato, Leonard Siew, Joy Edwards-Hicks, Reenam S. Khan, N. Thin Luu, Mark Thursz, Philip N. Newsome, Marc Martínez‐Llordella, Naina Shah, Robert I. Lechler, Ajay M. Shah, Alberto Sánchez‐Fueyo, Giovanna Lombardi, Niloufar Safinia - EBioMedicine 2023 cited by 34

  13. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

    Authors: Behdad Afzali, Giulia Lombardi, Robert I. Lechler, Graham M. Lord - Clinical & Experimental Immunology 2007 cited by 751

  14. The Future of Regulatory T Cell Therapy: Promises and Challenges of Implementing CAR Technology

    Authors: Yasmin R. Mohseni, Sim L. Tung, Caroline Dudreuilh, Robert I. Lechler, Gilbert O. Fruhwirth, Giovanna Lombardi - Frontiers in Immunology 2020 cited by 90

  15. Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation

    Authors: Amy Putnam, Niloufar Safinia, Andrew Medvec, Monika Laszkowska, M. Wray, Michelle A. Mintz, Eleonora Trotta, Gregory L. Szot, W Liu, Angela Lares, K. Lee, Adam Laing, Robert I. Lechler, James L. Riley, Jeffrey A. Bluestone, Giulia Lombardi, Qizhi Tang - American Journal of Transplantation 2013 cited by 255

  16. PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype

    Authors: Giorgia Fanelli, Marco Romano, Estefanía Nova‐Lamperti, Mariana Werner Sunderland, Alessandra Nerviani, Cristiano Scottà, Michele Bombardieri, Sergio A. Quezada, Steven H. Sacks, Randolph J. Noelle, Costantino Pitzalis, Robert I. Lechler, Giovanna Lombardi, Pablo D. Becker - PLoS Biology 2021 cited by 67

  17. Regulatory T Cell-Derived Exosomes: Possible Therapeutic and Diagnostic Tools in Transplantation

    Authors: Akansha Agarwal, Giorgia Fanelli, Marilena Letizia, Sim L. Tung, Dominic Boardman, Robert I. Lechler, Giovanna Lombardi, Lesley A. Smyth - Frontiers in Immunology 2014 cited by 105

  18. Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice

    Authors: Julia Yuen-Shan Tsang, Yakup Tanriver, Shuiping Jiang, Shao‐An Xue, Kulachelvy Ratnasothy, Daxin Chen, Hans J. Stauss, R. Pat Bucy, Giovanna Lombardi, Robert I. Lechler - Journal of Clinical Investigation 2008 cited by 267

  19. Successful expansion of functional and stable regulatory T cells for immunotherapy in liver transplantation

    Authors: Niloufar Safinia, Trishan Vaikunthanathan, Henrieta Fraser, Sarah Thirkell, Katie Lowe, Laura Blackmore, Gavin Whitehouse, Marc Martínez‐Llordella, Wayel Jassem, Alberto Sánchez‐Fueyo, Robert I. Lechler, Giovanna Lombardi - Oncotarget 2016 cited by 145

  20. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

    Authors: I. Sadaf Farooqi, Giuseppe Matarese, Graham M. Lord, Julia M. Keogh, Elizabeth Lawrence, Chizo Agwu, Veronica Sanna, Susan A. Jebb, F Perna, Silvia Fontana, Robert I. Lechler, Alex M. DePaoli, Stephen O’Rahilly - Journal of Clinical Investigation 2002 cited by 1,326

  21. Identification of a B cell signature associated with renal transplant tolerance in humans

    Authors: Kenneth A. Newell, Adam L. Asare, Allan D. Kirk, Trang Gisler, Kasia Bourcier, Manikkam Suthanthiran, William J. Burlingham, William H. Marks, Igñacio Sanz, Robert I. Lechler, María P. Hernández-Fuentes, Laurence A. Turka, Vicki Seyfert‐Margolis - Journal of Clinical Investigation 2010 cited by 669

  22. Expanded Regulatory T Cells Induce Alternatively Activated Monocytes With a Reduced Capacity to Expand T Helper-17 Cells

    Authors: Marco Romano, Giorgia Fanelli, Nicole Tan, Estefanía Nova‐Lamperti, Reuben McGregor, Robert I. Lechler, Giovanna Lombardi, Cristiano Scottà - Frontiers in Immunology 2018 cited by 84

  23. Chimeric antigen receptor‐modified human regulatory T cells that constitutively express IL‐10 maintain their phenotype and are potently suppressive

    Authors: Yasmin R. Mohseni, Adeel Saleem, Sim L. Tung, Caroline Dudreuilh, Cameron Lang, Qi Peng, Alessia Volpe, George Adigbli, Amy Cross, Joanna Hester, Farzin Farzaneh, Cristiano Scottà, Robert I. Lechler, Fadi Issa, Gilbert O. Fruhwirth, Giovanna Lombardi - European Journal of Immunology 2021 cited by 37

  24. Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations

    Authors: Cristiano Scottà, Mauro Esposito, Henrieta Fazekasova, Gregory C. Fanelli, Francis C. Edozie, Niwa Ali, Fang Xiao, Mark Peakman, Behdad Afzali, Pervinder Sagoo, Robert I. Lechler, Giovanna Lombardi - Haematologica 2012 cited by 148