Robert L. Coffman
Active 1971–2025
- 152
- Papers
- 71,157
- Citations
- 112
- h-index
- 151
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology44.1%
- Medicine38.8%
- Biochemistry, Genetics and Molecular Biology10.9%
- Neuroscience1.9%
- Agricultural and Biological Sciences1.4%
- Dentistry0.5%
- Other2.4%
Topics
- Immune Cell Function and Interaction9.4%
- T-cell and B-cell Immunology8.4%
- Immunotherapy and Immune Responses6.3%
- Immune Response and Inflammation4.8%
- Asthma and respiratory diseases2.7%
- IL-33, ST2, and ILC Pathways2.1%
- Other66.3%
Coauthors
- Franck J. Barrat16
- Cristiana Guiducci13
- Smita Mauze11
- Fiona Powrie10
- Deborah A. Lebman8
- Tim R. Mosmann8
- Edith M. Hessel7
- M W Bond7
- Alan Sher6
- Brian W. P. Seymour6
- Jean H. Chan6
- Paul B. Rothman6
- Satish Menon6
- Timothy R. Mosmann6
- Anne O’Garra5
- B Shrader5
- Holger Kanzler5
- Michael W. Leach5
- Albert F. Candia4
- D Rennick4
- Françoise Cottrez4
- Frederick W. Alt4
- Herbert C. Morse4
- Josh Gregorio4
All papers
- Interleukin-10 and the Interleukin-10 Receptor
Authors: Kevin W. Moore, René de Waal Malefyt, Robert L. Coffman, Anne O’Garra - Annual Review of Immunology 2001 cited by 6,696
- Vaccine Adjuvants: Putting Innate Immunity to Work
Authors: Robert L. Coffman, Alan Sher, Robert A. Seder - Immunity 2010 cited by 1,915
- Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus
Authors: Gina Stella García-Romo, Simone Caielli, Barbara Vega, John E. Connolly, Florence Allantaz, Zhaohui Xu, Marilynn Punaro, Jeanine Baisch, Cristiana Guiducci, Robert L. Coffman, Franck J. Barrat, Jacques Banchereau, Virginia Pascual - Science Translational Medicine 2011 cited by 1,368
- Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
Authors: Timothy R. Mosmann, Holly Cherwinski, M W Bond, Martin Giedlin, Robert L. Coffman - The Journal of Immunology 1986 cited by 7,504
- TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties
Authors: Tim R. Mosmann, Robert L. Coffman - Annual Review of Immunology 1989 cited by 7,598
- Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
Authors: Prabhu S. Arunachalam, Alexandra C. Walls, Nadia Golden, Caroline Atyeo, Stephanie Fischinger, Chunfeng Li, Pyone P. Aye, Mary Jane Navarro, Lilin Lai, Venkata Viswanadh Edara, Katharina Röltgen, Kenneth A. Rogers, Lisa Shirreff, Douglas E. Ferrell, Samuel Wrenn, Deleah Pettie, John C. Kraft, Marcos C. Miranda, Elizabeth Kepl, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Alexander G. White, Meera Trisal, Ching‐Lin Hsieh, Kasi Russell‐Lodrigue, Christopher Monjure, Jason Dufour, Skye Spencer, Lara Doyle‐Meyers, Rudolph P. Bohm, Nicholas J. Maness, Chad J. Roy, Jessica A. Plante, Kenneth S. Plante, Alex Zhu, Matthew J. Gorman, Sally Shin, Xiaoying Shen, Jane Fontenot, Shakti Gupta, Derek T. O’Hagan, Robbert van der Most, Rino Rappuoli, Robert L. Coffman, David Novack, Jason S. McLellan, Shankar Subramaniam, David C. Montefiori, Scott D. Boyd, JoAnne L. Flynn, Galit Alter, François Villinger, Harry Kleanthous, Jay Rappaport, Mehul S. Suthar, Neil P. King, David Veesler, Bali Pulendran - Nature 2021 cited by 353
- Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9
Authors: Irma García‐Martinez, Nicola Santoro, Yonglin Chen, Rafaz Hoque, Xinshou Ouyang, Sonia Caprio, Mark J. Shlomchik, Robert L. Coffman, Albert F. Candia, Wajahat Z. Mehal - Journal of Clinical Investigation 2016 cited by 475
- SD-101 in Combination with Pembrolizumab in Advanced Melanoma: Results of a Phase Ib, Multicenter Study
Authors: Antoni Ribas, Theresa Medina, Shivaani Kummar, Asim Amin, Anusha Kalbasi, Joseph J. Drabick, Minal Barve, Gregory A. Daniels, Deborah Jean Lee Wong, Emmett V. Schmidt, Albert F. Candia, Robert L. Coffman, Abraham C.F. Leung, Robert S. Janssen - Cancer Discovery 2018 cited by 341
- Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer
Authors: Fumi Sato-Kaneko, Shiyin Yao, Alast Ahmadi, Shannon Zhang, Tadashi Hosoya, Megan M. Kaneda, Judith A. Varner, Minya Pu, Karen Messer, Cristiana Guiducci, Robert L. Coffman, Kazutaka Kitaura, Takaji Matsutani, Ryuji Suzuki, Dennis A. Carson, Tomoko Hayashi, Ezra E.W. Cohen - JCI Insight 2017 cited by 287
- Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8 + T cells
Authors: Shu Wang, Jose Campos, Marilena Gallotta, Mei Gong, Chad Crain, Edwina Naik, Robert L. Coffman, Cristiana Guiducci - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 227
- Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
Authors: Franck J. Barrat, Thea Meeker, Josh Gregorio, Jean H. Chan, Satoshi Uematsu, Shizuo Akira, Bonnie Chang, Omar Duramad, Robert L. Coffman - The Journal of Experimental Medicine 2005 cited by 920
- An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation
Authors: Chrystelle Asseman, Smita Mauze, Michael W. Leach, Robert L. Coffman, Fiona Powrie - The Journal of Experimental Medicine 1999 cited by 1,588
- Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
Authors: Fiona Powrie, Michael W. Leach, Smita Mauze, Satish Menon, Linda Barcomb Caddle, Robert L. Coffman - Immunity 1994 cited by 1,146
- In Situ Vaccination with a TLR9 Agonist and Local Low-Dose Radiation Induces Systemic Responses in Untreated Indolent Lymphoma
Authors: Matthew J. Frank, Patrick M. Reagan, Nancy L. Bartlett, Leo I. Gordon, Jonathan W. Friedberg, Debra K. Czerwinski, Steven Long, Richard T. Hoppe, Robert S. Janssen, Albert F. Candia, Robert L. Coffman, Ronald Levy - Cancer Discovery 2018 cited by 188
- Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells
Authors: Tracy L. Stevens, A Bossie, Virginia M. Sanders, Rafael Fernandez-Botrán, Robert L. Coffman, Timothy R. Mosmann, Ellen S. Vitetta - Nature 1988 cited by 947
- TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus
Authors: Cristiana Guiducci, Mei Gong, Zhaohui Xu, Michelle A. Gill, Damien Chaussabel, Thea Meeker, Jean H. Chan, Tracey Wright, Marilynn Punaro, Silvia Bolland, Vassili Soumelis, Jacques Banchereau, Robert L. Coffman, Virginia Pascual, Franck J. Barrat - Nature 2010 cited by 374
- OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response
Authors: C. Jacquemin, Nathalie Schmitt, Cécile Contin‐Bordes, Yang Liu, Priya Narayanan, Julien Sénéschal, Typhanie Maurouard, David S. Dougall, Emily Spence Davizon, Hélène Dumortier, Isabelle Douchet, Loïc Raffray, Christophe Richez, Estibaliz Lazaro, P. Duffau, Marie‐Elise Truchetet, Liliane Khoryati, P. Mercié, Lionel Couzi, Pierre Merville, Thierry Schaeverbeke, Jean‐François Viallard, Jean‐Luc Pellegrin, Jean‐François Moreau, Sylviane Muller, Sandy Zurawski, Robert L. Coffman, Virginia Pascual, Hideki Ueno, Patrick Blanco - Immunity 2015 cited by 223
- Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19
Authors: Tsun-Yung Kuo, Meei‐Yun Lin, Robert L. Coffman, John D. Campbell, Paula Traquina, Yi-Jiun Lin, Luke Tzu-Chi Liu, Jinyi Cheng, Yu-Chi Wu, Chung-Chin Wu, Wei-Hsuan Tang, Chung‐Guei Huang, Kuo‐Chien Tsao, Charles Chen - Scientific Reports 2020 cited by 180
- Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
Authors: Flona Powrie, Michael W. Leach, Smita Mauze, Linda Barcomb Caddie, Robert L. Coffman - International Immunology 1993 cited by 1,072
- RNA recognition by human TLR8 can lead to autoimmune inflammation
Authors: Cristiana Guiducci, Mei Gong, Alma‐Martina Cepika, Zhaohui Xu, Claudio Tripodo, Lynda Bennett, Chad Crain, Pierre Quartier, John J. Cush, Virginia Pascual, Robert L. Coffman, Franck J. Barrat - The Journal of Experimental Medicine 2013 cited by 202
- Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
Authors: Holger Kanzler, Franck J. Barrat, Edith M. Hessel, Robert L. Coffman - Nature Medicine 2007 cited by 862
- Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice
Authors: Lilit Grigoryan, Audrey Lee, Alexandra C. Walls, Lilin Lai, Benjamin Franco, Prabhu S. Arunachalam, Yupeng Feng, Wei Luo, Abigail Vanderheiden, Katharine Floyd, Samuel Wrenn, Deleah Pettie, Marcos C. Miranda, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Robert L. Coffman, David Novack, Harry Kleanthous, Derek T. O’Hagan, Robbert van der Most, Jason S. McLellan, Mehul S. Suthar, David Veesler, Neil P. King, Bali Pulendran - npj Vaccines 2022 cited by 55
- Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures.
Authors: Deborah A. Lebman, Robert L. Coffman - The Journal of Experimental Medicine 1988 cited by 368
- Selective Utilization of Toll-like Receptor and MyD88 Signaling in B Cells for Enhancement of the Antiviral Germinal Center Response
Authors: Baidong Hou, Philippe Saudan, Gary Ott, Matthew L. Wheeler, Ming Ji, Lili Kuzmich, Linda M. Lee, Robert L. Coffman, Martin F. Bachmann, Anthony DeFranco - Immunity 2011 cited by 234
