Robert T. Abraham
Active 1975–2025
- 117
- Papers
- 36,870
- Citations
- 94
- h-index
- 117
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology50.5%
- Medicine35.7%
- Immunology and Microbiology8.2%
- Neuroscience1.9%
- Agricultural and Biological Sciences0.9%
- Chemistry0.8%
- Other2%
Topics
- PI3K/AKT/mTOR signaling in cancer5.6%
- Autophagy in Disease and Therapy5%
- DNA Repair Mechanisms4%
- Cancer-related Molecular Pathways3.3%
- Cancer, Hypoxia, and Metabolism2.3%
- Immune Cell Function and Interaction2.2%
- Other77.6%
Coauthors
- Larry M. Karnitz13
- Ker Yu9
- Paul J. Leibson9
- Gary G. Chiang8
- James J. Gibbons8
- Judy Lucas8
- Christina H. Eng7
- Garth Powis7
- Shari L. Sutor7
- Lourdes Toral‐Barza6
- Randal S. Tibbetts6
- Weiguo Zhang6
- Brandi L. Williams5
- Candace J. Sabers5
- Diane M. Otterness5
- John C. Lawrence5
- Kathryn M. Brumbaugh5
- Semiramis Ayral‐Kaloustian5
- Tarek S. Mansour5
- Boris Shor4
- Brenda J. Irvin4
- Fang Wang4
- Gregory J. Brunn4
- Gregory J. Wiederrecht4
All papers
- The PI3K Pathway in Human Disease
Authors: David A. Fruman, Honyin Chiu, Benjamin D. Hopkins, Shubha Bagrodia, Lewis C. Cantley, Robert T. Abraham - Cell 2017 cited by 2,764
- Guidelines for the use and interpretation of assays for monitoring autophagy
Authors: Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich, Robert T. Abraham, Abraham Acevedo‐Arozena, Khosrow Adeli, Lotta Agholme, Maria Agnello, Patrizia Agostinis, Julio A. Aguirre‐Ghiso, Hyung Jun Ahn, Ouardia Aït-Mohamed, Slimane Ait‐Si‐Ali, Takahiko Akematsu, Shizuo Akira, Hesham M. Al‐Younes, Munir A. Al‐Zeer, Matthew L. Albert, Roger L. Albin, Javier Alegre‐Abarrategui, Maria Francesca Aleo, Mehrdad Alirezaei, Alexandru Almasan, Maylin Almonte‐Becerril, Atsuo Amano, Ravi K. Amaravadi, Shoba Amarnath, Amal O. Amer, Nathalie Andrieu‐Abadie, Vellareddy Anantharam, David K. Ann, Shailendra Anoopkumar‐Dukie, Hiroshi Aoki, Nadezda Apostolova, Giuseppe Arancia, John P. Aris, Katsuhiko Asanuma, Nana Asare, Hisashi Ashida, Valerie Askanas, David S. Askew, Patrick Auberger, Misuzu Baba, Steven K. Backues, Eric H. Baehrecke, Ben A. Bahr, Xue-Yuan Bai, Yannick Bailly, Robert A. Baiocchi, Giulia Baldini, Walter Balduini, Andrea Ballabio, Bruce A. Bamber, Edward T. W. Bampton, Gábor Juhász, Clinton R. Bartholomew, Diane C. Bassham, Robert C. Bast, Henri Batoko, Boon-Huat Bay, Isabelle Beau, Daniel M. Béchet, Thomas J. Begley, Christian Behl, Christian Behrends, Soumeya Bekri, Bryan H. Bellaire, Linda J. Bendall, Luca Benetti, Laura Berliocchi, Henri Bernardi, Francesca Bernassola, Sébastien Besteiro, Ingrid Bhatia-Kissova, Xiaoning Bi, Martine Biard-Piechaczyk, Janice S. Blum, Lawrence Boise, Paolo Bonaldo, David L. Boone, Beat Bornhäuser, Karina Ramalho Bortoluci, Ioannis Bossis, Frédéric Bost, Jean‐Pierre Bourquin, Patricia Boya, Michaël Boyer‐Guittaut, Peter V. Bozhkov, Nathan Brady, Claudio Brancolini, Andreas Brech, Jay E. Brenman, Ana Brennand, Emery Bresnick, Patrick Brest, Dave Bridges, Molly L. Bristol, Paul S. Brookes, Eric J. Brown, John H. Brumell and 1,170 more - Autophagy 2012 cited by 4,046
- Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
Authors: Anne‐Claude Gingras, Steven P. Gygi, Brian Raught, Roberto D. Polakiewicz, Robert T. Abraham, Merl F. Hoekstra, Ruedi Aebersold, Nahum Sonenberg - Genes & Development 1999 cited by 1,336
- Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase
Authors: Kristen A. Baltgalvis, Kelsey N. Lamb, Kent T. Symons, Chu-Chiao Wu, Melissa Hoffman, Aaron N. Snead, Xiaodan Song, Thomas Glaza, Shota Kikuchi, Jason C. Green, Donald C. Rogness, Betty Lam, Maria E. Rodriguez-Aguirre, David R. Woody, Christie L. Eissler, Socorro Rodiles, Seth M. Negron, Steffen M. Bernard, Eileen Tran, Jonathan Pollock, Ali Tabatabaei, Víctor Contreras, Heather N. Williams, Martha K. Pastuszka, J. Sigler, Piergiorgio Pettazzoni, M.G. Rudolph, Moritz Classen, Doris Brugger, Christopher F. Claiborne, Jean‐Marc Plancher, Isabel Cuartas, Joan Seoane, Laurence E. Burgess, Robert T. Abraham, David S. Weinstein, Gabriel M. Simon, Matthew P. Patricelli, Todd M. Kinsella - Nature 2024 cited by 102
- Cystine–glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity
Authors: Michael D. Arensman, Xiaoran Yang, Danielle Leahy, Lourdes Toral‐Barza, Mary Mileski, Edward Rosfjord, Fang Wang, Shibing Deng, Jeremy S. Myers, Robert T. Abraham, Christina H. Eng - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 171
- Molecular Pathways: Targeting the Cyclin D–CDK4/6 Axis for Cancer Treatment
Authors: Todd VanArsdale, Chris Boshoff, Kim Arndt, Robert T. Abraham - Clinical Cancer Research 2015 cited by 401
- Jurkat T cells and development of the T-cell receptor signalling paradigm
Authors: Robert T. Abraham, Arthur Weiss - Nature reviews. Immunology 2004 cited by 604
- Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy
Authors: Christina H. Eng, Ker Yu, Judy Lucas, Eileen White, Robert T. Abraham - Science Signaling 2010 cited by 343
- Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin
Authors: Christine C. Hudson, Mei Liu, Gary G. Chiang, Diane M. Otterness, Dawn C. Loomis, Fiona Kaper, Amato J. Giaccia, Robert T. Abraham - Molecular and Cellular Biology 2002 cited by 1,179
- Isolation of a Protein Target of the FKBP12-Rapamycin Complex in Mammalian Cells
Authors: Candace J. Sabers, Mary M. Martin, Gregory J. Brunn, Josie M. Williams, Francis J. Dumont, Gregory J. Wiederrecht, Robert T. Abraham - Journal of Biological Chemistry 1995 cited by 876
- Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
Authors: Christina H. Eng, Zuncai Wang, Diane Tkach, Lourdes Toral‐Barza, Savuth Ugwonali, Shanming Liu, Stephanie Fitzgerald, Elizabeth George, Elizabeth Frias, Nadire R. Cochran, Rowena De Jesus, Gregory McAllister, Gregory R. Hoffman, Kevin Bray, LuAnna Lemon, Judy Lucas, Valeria R. Fantin, Robert T. Abraham, Leon O. Murphy, Beat Nyfeler - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 224
- Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase
Authors: Natasha Emmanuel, Shoba Ragunathan, Qin Shan, Fang Wang, Andreas Giannakou, Nanni Huser, Guixian Jin, Jeremy S. Myers, Robert T. Abraham, Keziban Ünsal-Kaçmaz - Cell Reports 2017 cited by 162
- Phosphorylation of Mammalian Target of Rapamycin (mTOR) at Ser-2448 IsMediated by p70S6 Kinase
Authors: Gary G. Chiang, Robert T. Abraham - Journal of Biological Chemistry 2005 cited by 558
- Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound 26 (PKI-587), a Highly Efficacious Dual Inhibitor
Authors: Aranapakam M. Venkatesan, Christoph M. Dehnhardt, Efren Delos Santos, Zecheng Chen, Osvaldo dos Santos, Semiramis Ayral‐Kaloustian, Gulnaz Khafizova, Natasja Brooijmans, Robert Mallon, Irwin Hollander, Larry Feldberg, Judy Lucas, Ker Yu, James J. Gibbons, Robert T. Abraham, Inder Chaudhary, Tarek S. Mansour - Journal of Medicinal Chemistry 2010 cited by 212
- Cell cycle checkpoint signaling through the ATM and ATR kinases
Authors: Robert T. Abraham - Genes & Development 2001 cited by 1,964
- Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.
Authors: Garth Powis, Rosanne Bonjouklian, Margareta Berggren, Alfred Gallegos, Robert T. Abraham, Curtis L. Ashendel, Leon H. Zalkow, William F. Matter, Jeffrey A. Dodge, Gerald B. Grindey - 1994 cited by 691
- A role for ATR in the DNA damage-induced phosphorylation of p53
Authors: Randal S. Tibbetts, Kathryn M. Brumbaugh, Jean Williams, Jann N. Sarkaria, William A. Cliby, Sheau-Yann Shieh, Yoichi Taya, Carol Prives, Robert T. Abraham - Genes & Development 1999 cited by 1,052
- Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin
Authors: Gregory J. Brunn, Christine C. Hudson, Aleksandar Sekulić, Josie M. Williams, Hajime Hosoi, Peter J. Houghton, John C. Lawrence, Robert T. Abraham - Science 1997 cited by 962
- Direct control of CAR T cells through small molecule-regulated antibodies
Authors: Spencer Park, Edward Pascua, Kevin C. Lindquist, Christopher R. Kimberlin, Xiaodi Deng, Yvonne S.L. Mak, Zea Melton, Theodore Johnson, Regina Lin, Bijan Boldajipour, Robert T. Abraham, Jaume Pons, Barbra J. Sasu, Thomas Van Blarcom, Javier Chaparro‐Riggers - Nature Communications 2021 cited by 50
- A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
Authors: A Sekulić, Christine C. Hudson, J L Homme, P Yin, Diane M. Otterness, Larry M. Karnitz, Robert T. Abraham - 2000 cited by 716
- Functional Analysis of Human Microtubule-based Motor Proteins, the Kinesins and Dyneins, in Mitosis/Cytokinesis Using RNA Interference
Authors: Changjun Zhu, Jian Zhao, Marina Bibikova, Joel D. Leverson, Ella Bossy‐Wetzel, Jian‐Bing Fan, Robert T. Abraham, Wei Jiang - Molecular Biology of the Cell 2005 cited by 444
- Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling
Authors: Nathan T. Ihle, Ryan Williams, Sherry Chow, Wade M. Chew, Margareta Berggren, Gillian Paine-Murrieta, Daniel J. Minion, Robert J. Halter, Peter Wipf, Robert T. Abraham, Lynn Kirkpatrick, Garth Powis - Molecular Cancer Therapeutics 2004 cited by 312
- Glutamine: pleiotropic roles in tumor growth and stress resistance
Authors: Naval P. Shanware, Andrew R. Mullen, Ralph J. DeBerardinis, Robert T. Abraham - Journal of Molecular Medicine 2011 cited by 178
- Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002.
Authors: G.J. Brunn, Josie M. Williams, Candace J. Sabers, Greg Wiederrecht, John C. Lawrence, Robert T. Abraham - The EMBO Journal 1996 cited by 723
