Roger S. Lo
Active 1994–2024
- 70
- Papers
- 32,988
- Citations
- 60
- h-index
- 70
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology44.2%
- Medicine43.6%
- Immunology and Microbiology8.5%
- Engineering1.2%
- Computer Science0.6%
- Neuroscience0.5%
- Other1.4%
Topics
- Cancer Immunotherapy and Biomarkers9.6%
- Melanoma and MAPK Pathways5.5%
- Immunotherapy and Immune Responses4.9%
- CAR-T cell therapy research3.3%
- Immune Cell Function and Interaction3%
- TGF-β signaling in diseases2.8%
- Other70.9%
Coauthors
- Antoni Ribas34
- Willy Hugo20
- Gatien Moriceau19
- Xiangju Kong18
- Shirley H. Lomeli13
- Jeffrey A. Sosman12
- Hubing Shi11
- Joan Massagué11
- Aayoung Hong10
- Georgina V. Long9
- Bartosz Chmielowski8
- Richard C. Koya8
- Sixue Liu8
- Douglas B. Johnson7
- Lu Sun7
- Thomas G. Graeber7
- Yan Wang7
- Chunying Song6
- Jennifer A. Wargo6
- Keith T. Flaherty6
- Kimberly B. Dahlman6
- Marco Piva6
- Richard A. Scolyer6
- Richard Kefford6
All papers
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
Authors: Willy Hugo, Jesse M. Zaretsky, Lu ming Sun, Chunying Song, Blanca Homet Moreno, Siwen Hu‐Lieskovan, Beata Berent-Maoz, Jia Pang, Bartosz Chmielowski, Grace Cherry, Elizabeth Seja, Shirley H. Lomeli, Xiangju Kong, Mark C. Kelley, Jeffrey A. Sosman, Douglas B. Johnson, Antoni Ribas, Roger S. Lo - Cell 2016 cited by 3,569
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
Authors: Jesse M. Zaretsky, Ángel García-Díaz, Daniel Sanghoon Shin, Helena Escuin-Ordinas, Willy Hugo, Siwen Hu‐Lieskovan, Davis Y. Torrejon, Gabriel Abril-Rodríguez, Salemiz Sandoval, Lucas Barthly, Justin D. Saco, Blanca Homet Moreno, Riccardo Mezzadra, Bartosz Chmielowski, Kathleen Ruchalski, I. Peter Shintaku, Phillip J. Sanchez, Cristina Puig-Saus, Grace Cherry, Elizabeth Seja, Xiangju Kong, Jia Pang, Beata Berent-Maoz, Begoña Comı́n-Anduix, Thomas G. Graeber, Paul C. Tumeh, Ton N. Schumacher, Roger S. Lo, Antoni Ribas - New England Journal of Medicine 2016 cited by 3,167
- Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
Authors: Ángel García-Díaz, Daniel Sanghoon Shin, Blanca Homet Moreno, Justin D. Saco, Helena Escuin-Ordinas, Gabriel Abril Rodriguez, Jesse M. Zaretsky, Lu Sun, Willy Hugo, Xiaoyan Wang, Giulia Parisi, Cristina Puig-Saus, Davis Y. Torrejon, Thomas G. Graeber, Begonya Comin-Anduix, Siwen Hu‐Lieskovan, Robert Damoiseaux, Roger S. Lo, Antoni Ribas - Cell Reports 2017 cited by 1,911
- Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations
Authors: Daniel Sanghoon Shin, Jesse M. Zaretsky, Helena Escuin-Ordinas, Ángel García-Díaz, Siwen Hu‐Lieskovan, Anusha Kalbasi, Catherine S. Grasso, Willy Hugo, Salemiz Sandoval, Davis Y. Torrejon, Nicolaos Palaskas, Gabriel Abril Rodriguez, Giulia Parisi, Ariel M. Azhdam, Bartosz Chmielowski, Grace Cherry, Elizabeth Seja, Beata Berent-Maoz, I. Peter Shintaku, Dung T. Le, Drew M. Pardoll, Luis A. Díaz, Paul C. Tumeh, Thomas G. Graeber, Roger S. Lo, Begoña Comı́n-Anduix, Antoni Ribas - Cancer Discovery 2016 cited by 1,288
- Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
Authors: Ravid Straussman, Teppei Morikawa, Kevin Shee, Michal Barzily-Rokni, Zhi Rong Qian, Jinyan Du, Ashli Davis, Margaret Mongare, Joshua Gould, Dennie T. Frederick, Zachary A. Cooper, Paul B. Chapman, David B. Solit, Antoni Ribas, Roger S. Lo, Keith T. Flaherty, Shuji Ogino, Jennifer A. Wargo, Todd R. Golub - Nature 2012 cited by 1,760
- Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
Authors: Ramin Nazarian, Hubing Shi, Qi Wang, Xiangju Kong, Richard C. Koya, Hane Lee, Zugen Chen, Mi‐Kyung Lee, Narsis Attar, Hooman Sazegar, Thinle Chodon, Stanley F. Nelson, Grant A. McArthur, Jeffrey A. Sosman, Antoni Ribas, Roger S. Lo - Nature 2010 cited by 2,174
- RETRACTED ARTICLE: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
Authors: Amanpreet Kaur, Marie R. Webster, Katie Marchbank, Reeti Behera, Abibatou Ndoye, Curtis H. Kugel, Vanessa Dang, Jessica Appleton, Michael P. O’Connell, Phil F. Cheng, Alexander A. Valiga, Rachel Morissette, Nazli B. McDonnell, Luigi Ferrucci, Andrew V. Kossenkov, Katrina Meeth, Hsin‐Yao Tang, Xiangfan Yin, William H. Wood, Elin Lehrmann, Kevin G. Becker, Keith T. Flaherty, Dennie T. Frederick, Jennifer A. Wargo, Zachary A. Cooper, Michael T. Tetzlaff, Courtney W. Hudgens, Katherine M. Aird, Rugang Zhang, Xiaowei Xu, Qin Liu, Edmund K. Bartlett, Giorgos C. Karakousis, Zeynep Eroglu, Roger S. Lo, Matthew Chan, Alexander M. Menzies, Georgina V. Long, Douglas B. Johnson, Jeffrey A. Sosman, Bastian Schilling, Dirk Schadendorf, David W. Speicher, Marcus Bosenberg, Antoni Ribas, Ashani T. Weeraratna - Nature 2016 cited by 390
- RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
Authors: Poulikos I. Poulikakos, Yogindra Persaud, Manickam Janakiraman, Xiangju Kong, Charles Ng, Gatien Moriceau, Hubing Shi, Mohammad Atefi, Bjoern Titz, May Tal Gabay, Maayan Salton, Kimberly B. Dahlman, Madhavi Tadi, Jennifer A. Wargo, Keith T. Flaherty, Mark C. Kelley, Tom Misteli, Paul B. Chapman, Jeffrey A. Sosman, Thomas G. Graeber, Antoni Ribas, Roger S. Lo, Neal Rosen, David B. Solit - Nature 2011 cited by 1,454
- Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma
Authors: Judith M. Müller, Oscar Krijgsman, Jennifer Tsoi, Lídia Robert, Willy Hugo, Chunying Song, Xiangju Kong, Patrícia A. Possik, Paulien Cornelissen‐Steijger, Marnix H. Geukes Foppen, Kristel Kemper, Colin R. Goding, Ultan McDermott, Christian U. Blank, John B.A.G. Haanen, Thomas G. Graeber, Antoni Ribas, Roger S. Lo, Daniel S. Peeper - Nature Communications 2014 cited by 637
- Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH
Authors: King L. Hung, Jens Luebeck, Siavash R. Dehkordi, Caterina I. Colón, Rui Li, Ivy Tsz-Lo Wong, Ceyda Çoruh, Prashanthi Dharanipragada, Shirley H. Lomeli, Natasha E. Weiser, Gatien Moriceau, Xiao Zhang, Chris Bailey, Kathleen E. Houlahan, Wenting Yang, Rocío Chamorro González, Charles Swanton, Christina Curtis, Mariam Jamal‐Hanjani, Anton G. Henssen, Julie A. Law, William J. Greenleaf, Roger S. Lo, Paul S. Mischel, Vineet Bafna, Howard Y. Chang - Nature Genetics 2022 cited by 123
- Non-genomic and Immune Evolution of Melanoma Acquiring MAPKi Resistance
Authors: Willy Hugo, Hubing Shi, Lu Sun, Marco Piva, Chunying Song, Xiangju Kong, Gatien Moriceau, Aayoung Hong, Kimberly B. Dahlman, Douglas B. Johnson, Jeffrey A. Sosman, Antoni Ribas, Roger S. Lo - Cell 2015 cited by 619
- Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy
Authors: Hubing Shi, Willy Hugo, Xiangju Kong, Aayoung Hong, Richard C. Koya, Gatien Moriceau, Thinle Chodon, Rongqing Guo, Douglas B. Johnson, Kimberly B. Dahlman, Mark C. Kelley, Richard Kefford, Bartosz Chmielowski, John A. Glaspy, Jeffrey A. Sosman, Nicolas van Baren, Georgina V. Long, Antoni Ribas, Roger S. Lo - Cancer Discovery 2013 cited by 986
- Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation
Authors: Min Pan, Michael A. Reid, Xazmin H. Lowman, Rajan P. Kulkarni, Thai Q. Tran, Xiaojing Liu, Ying Yang, Jenny E. Hernandez‐Davies, Kimberly K. Rosales, Haiqing Li, Willy Hugo, Chunying Song, Xiangdong Xu, Dustin E. Schones, David K. Ann, Viviana Gradinaru, Roger S. Lo, Jason W. Locasale, Mei Kong - Nature Cell Biology 2016 cited by 371
- TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
Authors: Joan Massagué, Stacy W. Blain, Roger S. Lo - Cell 2000 cited by 2,379
- Blocking Genomic Instability Prevents Acquired Resistance to MAPK Inhibitor Therapy in Melanoma
Authors: Prashanthi Dharanipragada, Xiao Zhang, Sixue Liu, Shirley H. Lomeli, Aayoung Hong, Yan Wang, Zhentao Yang, Kara Z. Lo, Agustin Vega-Crespo, Antoni Ribas, Stergios J. Moschos, Gatien Moriceau, Roger S. Lo - Cancer Discovery 2023 cited by 84
- Therapy-induced tumour secretomes promote resistance and tumour progression
Authors: Anna C. Obenauf, Yilong Zou, Andrew L. Ji, Sakari Vanharanta, Weiping Shu, Hubing Shi, Xiangju Kong, Marcus Bosenberg, Thomas Wiesner, Neal Rosen, Roger S. Lo, Joan Massagué - Nature 2015 cited by 502
- Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma
Authors: Hannah M. Knochelmann, Joshua D. Horton, Sixue Liu, Kent Armeson, John M. Kaczmar, Megan M. Wyatt, Mary S. Richardson, Shirley H. Lomeli, Ying Xiong, Evan M. Graboyes, Eric J. Lentsch, Joshua D. Hornig, Judith M. Skoner, Seth Stalcup, Maria Vittoria Spampinato, Elizabeth Garrett‐Mayer, Elizabeth C. O’Quinn, Cynthia Timmers, Martin J. Romeo, John Wrangle, Matthew R. Young, Mark P. Rubinstein, Terry A. Day, Roger S. Lo, Chrystal M. Paulos, David M. Neskey - Cell Reports Medicine 2021 cited by 97
- Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
Authors: Michael Krauthammer, Yong Kong, Byung Hak Ha, Perry Evans, Antonella Bacchiocchi, Jamie P. McCusker, Elaine Cheng, Matthew J. Davis, Gerald Goh, Murim Choi, Stephan Ariyan, Deepak Narayan, Ken Dutton‐Regester, Ana Capatana, Edna C. Holman, Marcus Bosenberg, Mario Sznol, Harriet M. Kluger, Douglas E. Brash, David F. Stern, Miguel A. Materin, Roger S. Lo, Shrikant Mane, Shuangge Ma, Kenneth K. Kídd, Nicholas K. Hayward, Richard P. Lifton, Joseph Schlessinger, Titus J. Boggon, Ruth Halaban - Nature Genetics 2012 cited by 1,192
- Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms
Authors: Douglas B. Johnson, Alexander M. Menzies, Lisa Zimmer, Zeynep Eroglu, Fei Ye, Shilin Zhao, Helen Rizos, Antje Sucker, Richard A. Scolyer, Ralf Gutzmer, Helen Gogas, Richard Kefford, John F. Thompson, Jürgen C. Becker, Carola Berking, Friederike Egberts, Carmen Loquai, Simone M. Goldinger, Gulietta M. Pupo, Willy Hugo, Xiangju Kong, Levi A. Garraway, Jeffrey A. Sosman, Antoni Ribas, Roger S. Lo, Georgina V. Long, Dirk Schadendorf - European Journal of Cancer 2015 cited by 330
- Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy
Authors: Yujue Wang, Sixue Liu, Zhentao Yang, Alain P. Algazi, Shirley H. Lomeli, Yan Wang, Megan Othus, Aayoung Hong, Xiaoyan Wang, Chris E. Randolph, Alexis M. Jones, Marcus Bosenberg, Stephanie D. Byrum, Alan J. Tackett, Henry Lopez, Clayton Yates, David B. Solit, Antoni Ribas, Marco Piva, Gatien Moriceau, Roger S. Lo - Cancer Cell 2021 cited by 135
- Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
Authors: Kai Song, Jenna K. Minami, Arthur Huang, Siavash R. Dehkordi, Shirley H. Lomeli, Jens Luebeck, Mark H. Goodman, Gatien Moriceau, Oscar Krijgsman, Prashanthi Dharanipragada, Trevor Ridgley, William P. Crosson, Jesus Salazar, Eli Pazol, Gabriel Karin, Rachana Jayaraman, Nikolas G. Balanis, Salwan Alhani, Kyle Sheu, Johanna ten Hoeve, Amelia Palermo, Stephen E. Motika, T. Niroshi Senaratne, Kim H. Paraiso, Paul J. Hergenrother, P. Nagesh Rao, Asha S. Multani, Daniel S. Peeper, Vineet Bafna, Roger S. Lo, Thomas G. Graeber - Cancer Discovery 2021 cited by 77
- Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance
Authors: Hubing Shi, Gatien Moriceau, Xiangju Kong, Mi‐Kyung Lee, Hane Lee, Richard C. Koya, Charles Ng, Thinle Chodon, Richard A. Scolyer, Kimberly B. Dahlman, Jeffrey A. Sosman, Richard Kefford, Georgina V. Long, Stanley F. Nelson, Antoni Ribas, Roger S. Lo - Nature Communications 2012 cited by 620
- RAS Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors
Authors: Fei Su, Amaya Virós, Carla Milagre, Kerstin Trunzer, Gideon Bollag, Olivia Spleiss, Jorge S. Reis‐Filho, Xiangju Kong, Richard C. Koya, Keith T. Flaherty, Paul B. Chapman, Min Jung Kim, Robert Hayward, Matthew J. Martin, Hong Yang, Qiongqing Wang, Holly Hilton, Julie S. Hang, Johannes Noé, Maryou Lambros, Felipe C. Geyer, Nathalie Dhomen, Ion Niculescu‐Duvaz, Alfonso Zambon, Dan Niculescu‐Duvaz, Natasha Preece, Lídia Robert, Nicholas Otte, Stephen Mok, Damien Kee, Yan Ma, Chao Zhang, Gaston Habets, Elizabeth A. Burton, Bernice H. Wong, Hoa Nguyen, Mark Kockx, Luc Andries, Brian Lestini, K. B. Nolop, Richard J. Lee, Andrew K. Joe, James L. Troy, René González, Thomas E. Hutson, Igor Puzanov, Bartosz Chmielowski, Caroline J. Springer, Grant A. McArthur, Jeffrey A. Sosman, Roger S. Lo, Antoni Ribas, Richard Marais - New England Journal of Medicine 2012 cited by 1,028
- The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance
Authors: Justin L. Engel, Xiao Zhang, Mingming Wu, Yan Wang, Jose Espejo Valle-Inclán, Qing Hu, Kidist S Woldehawariat, Mathijs A. Sanders, Agata Smogorzewska, Jin Chen, Isidro Cortés‐Ciriano, Roger S. Lo, Peter Ly - Cell 2024 cited by 54
