Simon A. Hawley
Active 1994–2024
- 46
- Papers
- 24,430
- Citations
- 43
- h-index
- 46
- i10-index
Citations
Citation sources
Countries
Institutions
- Inserm1.1%
- University of Dundee1.1%
- Harvard University1%
- Centre National de la Recherche Scientifique0.9%
- Université Paris Cité0.7%
- Institut Cochin0.6%
- Other94.6%
Fields
- Biochemistry, Genetics and Molecular Biology51.7%
- Medicine35.8%
- Neuroscience4.2%
- Immunology and Microbiology2.7%
- Agricultural and Biological Sciences2.7%
- Nursing0.7%
- Other2.2%
Topics
- Metabolism, Diabetes, and Cancer12.8%
- Pancreatic function and diabetes6.6%
- Adipose Tissue and Metabolism5%
- Autophagy in Disease and Therapy4.1%
- Cancer, Hypoxia, and Metabolism3.3%
- Mitochondrial Function and Pathology2.5%
- Other65.7%
Coauthors
- D. Grahame Hardie44
- Fiona A. Ross12
- Kirsty J. Mustard6
- Kevin A. Green5
- Benoı̂t Viollet4
- David Carling4
- Gregory R. Steinberg4
- Ian P. Salt4
- Kei Sakamoto4
- Angela Woods3
- Chen‐Song Zhang3
- David Pan3
- Douglas J. Lamont3
- Fiona M. Russell3
- Graeme J. Gowans3
- Hai‐long Piao3
- Jin-Wei Feng3
- John W. Scott3
- Mengqi Li3
- Sarah Fogarty3
- Sheng‐Cai Lin3
- Stephen Davies3
- Zhichao Wang3
- Abdelmadjid Atrih2
All papers
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
Authors: D. Grahame Hardie, Fiona A. Ross, Simon A. Hawley - Nature Reviews Molecular Cell Biology 2012 cited by 4,473
- Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
Authors: Chen‐Song Zhang, Simon A. Hawley, Yue Zong, Mengqi Li, Zhichao Wang, Alexander Gray, Teng Ma, Jiwen Cui, Jin-Wei Feng, Mingjiang Zhu, Yuqing Wu, Terytty Yang Li, Zhiyun Ye, Shu‐Yong Lin, Huiyong Yin, Hai‐long Piao, D. Grahame Hardie, Sheng‐Cai Lin, Sheng‐Cai Lin, Sheng‐Cai Lin - Nature 2017 cited by 736
- Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy
Authors: Joshua C. Drake, Rebecca J. Wilson, Rhianna C. Laker, Yuntian Guan, Hannah R. Spaulding, Anna S. Nichenko, Wenqing Shen, Huayu Shang, Maya V. Dorn, Kian A Huang, Mei Zhang, Aloka B. Bandara, Matthew H. Brisendine, Jennifer A. Kashatus, Poonam Sharma, A. P. Young, Jitendra Gautam, Ruofan Cao, Horst Wallrabe, Paul Chang, Michael Wong, Eric M. Desjardins, Simon A. Hawley, George J. Christ, David F. Kashatus, Clint L. Miller, Matthew J. Wolf, Ammasi Periasamy, Gregory R. Steinberg, D. Grahame Hardie, Zhen Yan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 196
- Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
Authors: Simon A. Hawley, David Pan, Kirsty J. Mustard, Louise C. Ross, Jenny Bain, Arthur Edelman, Bruno G. Frenguelli, D. Grahame Hardie - Cell Metabolism 2005 cited by 1,567
- The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels
Authors: Simon A. Hawley, Rebecca J. Ford, Brennan K. Smith, Graeme J. Gowans, Sarah J. Mancini, Ryan D. Pitt, Emily A. Day, Ian P. Salt, Gregory R. Steinberg, D. Grahame Hardie - Diabetes 2016 cited by 386
- LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
Authors: José M. Lizcano, Olga Göransson, Rachel Toth, Mária Deák, Nick Morrice, Jérôme Boudeau, Simon A. Hawley, Lina Udd, Tomi P. Mäkelä, D. Grahame Hardie, Dario R. Alessi - The EMBO Journal 2004 cited by 1,372
- Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
Authors: Simon A. Hawley, Fiona A. Ross, Cyrille Chevtzoff, Kevin A. Green, A. Mark Evans, Sarah Fogarty, Mhairi C. Towler, Laura A. Brown, Oluseye A. Ogunbayo, A. Mark Evans, D. Grahame Hardie - Cell Metabolism 2010 cited by 763
- Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase
Authors: Simon A. Hawley, Matt Davison, Angela Woods, Stephen Davies, Raj K. Beri, David Carling, D. Grahame Hardie - Journal of Biological Chemistry 1996 cited by 1,262
- Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade
Authors: Simon A. Hawley, Jérôme Boudeau, Jennifer L. Reid, Kirsty J. Mustard, Lina Udd, Tomi P. Mäkelä, Dario R. Alessi, D. Grahame Hardie - Journal of Biology 2003 cited by 1,640
- The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
Authors: Simon A. Hawley, Morgan D. Fullerton, Fiona A. Ross, Jonathan D. Schertzer, Cyrille Chevtzoff, Katherine J. Walker, Mark Peggie, Darya Zibrova, Kevin A. Green, Kirsty J. Mustard, Bruce E. Kemp, Kei Sakamoto, Gregory R. Steinberg, D. Grahame Hardie - Science 2012 cited by 739
- Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis
Authors: Richard M. Reznick, Haihong Zong, Ji Li, Katsutaro Morino, Irene K. Moore, Hannah J. Yu, Zhen-Xiang Liu, Jianying Dong, Kirsty J. Mustard, Simon A. Hawley, Douglas E. Befroy, Marc Pypaert, D. Grahame Hardie, Lawrence H. Young, Gerald I. Shulman - Cell Metabolism 2007 cited by 541
- Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress
Authors: Yue Zong, Chen‐Song Zhang, Mengqi Li, Wen Wang, Zhichao Wang, Simon A. Hawley, Teng Ma, Jin-Wei Feng, Xiao Tian, Qi Qu, Yuqing Wu, Cixiong Zhang, Zhiyun Ye, Shu‐Yong Lin, Hai‐long Piao, D. Grahame Hardie, Sheng‐Cai Lin, Sheng‐Cai Lin, Sheng‐Cai Lin - Cell Research 2019 cited by 172
- 5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?
Authors: Julia M. Corton, John G. Gillespie, Simon A. Hawley, D. Grahame Hardie - European Journal of Biochemistry 1995 cited by 1,189
- AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Authors: Graeme J. Gowans, Simon A. Hawley, Fiona A. Ross, D. Grahame Hardie - Cell Metabolism 2013 cited by 523
- Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
Authors: Mengqi Li, Chen‐Song Zhang, Jin-Wei Feng, Xiaoyan Wei, Cixiong Zhang, Changchuan Xie, Yaying Wu, Simon A. Hawley, Abdelmadjid Atrih, Douglas J. Lamont, Zhichao Wang, Hai-long Piao, D. Grahame Hardie, Sheng‐Cai Lin - Cell Research 2020 cited by 80
- Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase
Authors: Olga Göransson, Andrew McBride, Simon A. Hawley, Fiona A. Ross, Natalia Shpiro, Marc Foretz, Benoı̂t Viollet, D. Grahame Hardie, Kei Sakamoto - Journal of Biological Chemistry 2007 cited by 438
- AMP‐activated protein kinase – development of the energy sensor concept
Authors: D. Grahame Hardie, Simon A. Hawley, John W. Scott - The Journal of Physiology 2006 cited by 807
- AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern
Authors: D. Grahame Hardie, Fiona A. Ross, Simon A. Hawley - Chemistry & Biology 2012 cited by 371
- CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations
Authors: John W. Scott, Simon A. Hawley, Kevin A. Green, Miliea Anis, G. A. Stewart, Gillian A. Scullion, D. Norman, D. Grahame Hardie - Journal of Clinical Investigation 2004 cited by 725
- The Antidiabetic Drug Metformin Activates the AMP-Activated Protein Kinase Cascade via an Adenine Nucleotide-Independent Mechanism
Authors: Simon A. Hawley, Anne E. Gadalla, Grith Skytte Olsen, D. Grahame Hardie - Diabetes 2002 cited by 688
- Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes
Authors: Péter Tamás, Simon A. Hawley, Rosemary G. Clarke, Kirsty J. Mustard, Kevin Green, D. Grahame Hardie, Doreen A. Cantrell - The Journal of Experimental Medicine 2006 cited by 325
- Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells
Authors: Simon A. Hawley, Fiona A. Ross, Graeme J. Gowans, Priyanka Tibarewal, Nicholas R. Leslie, D. Grahame Hardie - Biochemical Journal 2014 cited by 206
- Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK
Authors: Roger W. Hunter, Marc Foretz, Laurent Bultot, Morgan D. Fullerton, Mária Deák, Fiona A. Ross, Simon A. Hawley, Natalia Shpiro, Benoı̂t Viollet, Denís Barron, Bruce E. Kemp, Gregory R. Steinberg, D. Grahame Hardie, Kei Sakamoto - Chemistry & Biology 2014 cited by 125
- Mechanism of Activation of AMPK by Cordycepin
Authors: Simon A. Hawley, Fiona A. Ross, Fiona M. Russell, Abdelmadjid Atrih, Douglas J. Lamont, D. Grahame Hardie - Cell chemical biology 2020 cited by 63
