David Carling
Active 1987–2025
- 127
- Papers
- 50,876
- Citations
- 94
- h-index
- 124
- i10-index
Citations
Citation sources
Countries
Institutions
- Inserm1.1%
- Harvard University0.9%
- Centre National de la Recherche Scientifique0.7%
- University of Dundee0.7%
- Université Paris Cité0.5%
- University of Copenhagen0.5%
- Other95.6%
Fields
- Biochemistry, Genetics and Molecular Biology44.8%
- Medicine40.5%
- Neuroscience6.9%
- Agricultural and Biological Sciences2.3%
- Immunology and Microbiology2%
- Nursing1.2%
- Other2.3%
Topics
- Metabolism, Diabetes, and Cancer8.7%
- Adipose Tissue and Metabolism7%
- Pancreatic function and diabetes4.3%
- Adipokines, Inflammation, and Metabolic Diseases4.2%
- Regulation of Appetite and Obesity2.6%
- Diet and metabolism studies2.5%
- Other70.7%
Coauthors
- Angela Woods30
- D. Grahame Hardie25
- Lee G.D. Fryer11
- Matthew J. Sanders9
- Benoı̂t Viollet7
- Richard Heath7
- S.J. Gamblin7
- Alice Pollard6
- Fabienne Foufelle6
- Phillip Muckett6
- Raj K. Beri6
- Stephen Davies6
- Bing Xiao5
- Gregory R. Steinberg5
- Lucy Penfold5
- Marc Foretz5
- Marian Carlson5
- Stephen R. Bloom5
- Stephen R. Martin5
- Anissa A. Widjaja4
- Barbara B. Kahn4
- Ben Jones4
- Chad Whilding4
- Claire Thornton4
All papers
- The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism
Authors: Gary Frost, Michelle Sleeth, Meliz Sahuri-Arisoylu, Blanca Lizarbe, Sebastián Cerdán, Leigh Brody, Jelena Anastasovska, Samar Ghourab, Mohammed K. Hankir, Shuai Zhang, David Carling, Jonathan R. Swann, Glenn R. Gibson, Alexander Viardot, Douglas J. Morrison, E. Louise Thomas, Jimmy D. Bell - Nature Communications 2014 cited by 1,739
- AMP-activated protein kinase: the current landscape for drug development
Authors: Gregory R. Steinberg, David Carling - Nature Reviews Drug Discovery 2019 cited by 749
- AMPK signalling in health and disease
Authors: David Carling - Current Opinion in Cell Biology 2017 cited by 802
- Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
Authors: Toshimasa Yamauchi, Junji Kamon, Yasuhiko Minokoshi, Yusuke Ito, Hironori Waki, Shoko Uchida, Satoshi Yamashita, Mitsuhiko Noda, Shunbun Kita, Kohjiro Ueki, Kazuhiro Eto, Y Akanuma, Philippe Froguel, Fabienne Foufelle, Pascal Ferré, David Carling, Satoshi Kimura, R Nagai, Barbara B. Kahn, Takashi Kadowaki - Nature Medicine 2002 cited by 4,221
- Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
Authors: Anissa A. Widjaja, Wei‐Wen Lim, Siva Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schäfer, Benjamin L. George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A. Sims, Norbert Hübner, Enrico Petretto, Dominic J. Withers, Lena Ho, Jesús Gil, David Carling, Stuart A. Cook - Nature 2024 cited by 209
- Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
Authors: Angela Woods, Kristina Dickerson, Richard Heath, Seung Pyo Hong, Milica Momcilovic, Stephen R. Johnstone, Marian Carlson, David Carling - Cell Metabolism 2005 cited by 1,387
- AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
Authors: Barbara B. Kahn, Thierry Alquier, David Carling, D. Grahame Hardie - Cell Metabolism 2005 cited by 2,793
- Adenosine 5′-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype
Authors: Duygu Sağ, David Carling, Robert D. Stout, Jill Suttles - The Journal of Immunology 2008 cited by 796
- AMPK, insulin resistance, and the metabolic syndrome
Authors: Neil B. Ruderman, David Carling, Marc Prentki, José M. Cacicedo - Journal of Clinical Investigation 2013 cited by 867
- LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
Authors: Angela Woods, Stephen R. Johnstone, Kristina Dickerson, Fiona C. Leiper, Lee G.D. Fryer, Dietbert Neumann, Uwe Schlattner, Theo Wallimann, Marian Carlson, David Carling - Current Biology 2003 cited by 1,646
- Structure of mammalian AMPK and its regulation by ADP
Authors: Bing Xiao, Matthew J. Sanders, E. Underwood, Richard Heath, Faith V. Mayer, David Carmena, Chun Jing, P.A. Walker, John F. Eccleston, L.F. Haire, Peter Saiu, Steven Howell, Rein Aasland, Stephen R. Martin, David Carling, S.J. Gamblin - Nature 2011 cited by 927
- Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly
Authors: Elizabeth C. Hinchy, Anja V. Gruszczyk, Robin Willows, Naveenan Navaratnam, Andrew Hall, Georgina Bates, Thomas P. Bright, Thomas Krieg, David Carling, Michael P. Murphy - Journal of Biological Chemistry 2018 cited by 303
- Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
Authors: Yasuhiko Minokoshi, Young‐Bum Kim, Odile D. Peroni, Lee G.D. Fryer, Corinna Müller, David Carling, Barbara B. Kahn - Nature 2002 cited by 2,054
- Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase
Authors: Simon A. Hawley, Matt Davison, Angela Woods, Stephen Davies, Raj K. Beri, David Carling, D. Grahame Hardie - Journal of Biological Chemistry 1996 cited by 1,262
- Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
Authors: Colin Selman, Jennifer M. A. Tullet, Daniela Wieser, Elaine E. Irvine, Steven J. Lingard, Agharul I. Choudhury, Marc Claret, Hind Al‐Qassab, Danielle Carmignac, Faruk Ramadani, Angela Woods, Iain C. A. F. Robinson, Eugene F. Schuster, Rachel L. Batterham, Sara C. Kozma, George Thomas, David Carling, Klaus Okkenhaug, Janet M. Thornton, Linda Partridge, David Gems, Dominic J. Withers - Science 2009 cited by 1,131
- Structural basis of AMPK regulation by small molecule activators
Authors: Bing Xiao, Matthew J. Sanders, David Carmena, Nicola J. Bright, L.F. Haire, E. Underwood, Bhakti Patel, Richard Heath, P.A. Walker, Stefan Hallén, Fabrizio Giordanetto, Stephen R. Martin, David Carling, S.J. Gamblin - Nature Communications 2013 cited by 543
- Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
Authors: A-S. Marsin, Luc Bertrand, Mark H. Rider, Johan Deprez, Christophe Beauloye, M. F. Vincent, Greet Van den Berghe, David Carling, Louis Hue - Current Biology 2000 cited by 824
- A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis
Authors: David Carling, Victor A. Zammit, D. Grahame Hardie - FEBS Letters 1987 cited by 594
- Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
Authors: Miguel López, Luis Varela, María J. Vázquez, Sergio Rodríguez‐Cuenca, C. Ruth González, Vidya Velagapudi, Donald A. Morgan, Erik Schoenmakers, Khristofor Agassandian, Ricardo Lage, Pablo B. Martínez de Morentin, Sulay Tovar, Rubén Nogueiras, David Carling, Christopher J. Lelliott, Rosalı́a Gallego, Matej Orešič, Krishna Chatterjee, Asish K. Saha, Kamal Rahmouni, Carlos Diéguez, Antonio Vidal‐Puig - Nature Medicine 2010 cited by 676
- Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells
Authors: Robin Willows, Matthew J. Sanders, Bing Xiao, Bhakti Patel, Stephen R. Martin, Jon Read, J. Wilson, Julia Hubbard, S.J. Gamblin, David Carling - Biochemical Journal 2017 cited by 181
- Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet
Authors: Angela Woods, Jennet Williams, Phillip Muckett, Faith V. Mayer, Maria Liljevald, Mohammad Bohlooly‐Y, David Carling - Cell Reports 2017 cited by 207
- Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis
Authors: Pascale Gluais Dagorn, Marc Foretz, Gregory R. Steinberg, Battsetseg Batchuluun, Anna Zawistowska‐Deniziak, Joost M. Lambooij, Bruno Guigas, David Carling, Pierre‐Axel Monternier, David E. Moller, Sébastien Bolze, Sophie Hallakou‐Bozec - Hepatology Communications 2021 cited by 77
- Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma
Authors: Anke Nijhuis, Arti Sikka, Orli Yogev, Lili Herendi, Cristina Balcells, Yurui Ma, Evon Poon, Clare Eckold, Gabriel N. Valbuena, Yuewei Xu, Yusong Liu, Barbara Martins Da Costa, Michael Gruet, Chiharu Wickremesinghe, Adrián Benito, Holger Kramer, Alex Montoya, David Carling, Elizabeth J. Want, Yann Jamin, Louis Chesler, Hector C. Keun - Nature Communications 2022 cited by 117
- AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue
Authors: Alice Pollard, Luís Martins, Phillip Muckett, Sanjay Khadayate, Aurélie Bornot, Maryam Clausen, Therése Admyre, Mikael Bjursell, Rebeca Fiadeiro, Laura Wilson, Chad Whilding, Vassilios N. Kotiadis, Michael R. Duchen, Daniel Sutton, Lucy Penfold, Alessandro Sardini, Mohammad Bohlooly‐Y, David M. Smith, Jon Read, Michael Snowden, Angela Woods, David Carling - Nature Metabolism 2019 cited by 110
