Stephen J. Haggarty
Active 1998–2025
- 109
- Papers
- 31,236
- Citations
- 71
- h-index
- 105
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology53.3%
- Medicine19.5%
- Neuroscience10.5%
- Computer Science10.3%
- Chemistry1.2%
- Immunology and Microbiology1.2%
- Other4%
Topics
- Computational Drug Discovery Methods5.3%
- Histone Deacetylase Inhibitors Research4.2%
- Bioinformatics and Genomic Networks4.1%
- Epigenetics and DNA Methylation3.3%
- Genetics and Neurodevelopmental Disorders2.9%
- Protein Degradation and Inhibitors2.4%
- Other77.8%
Coauthors
- M. Catarina Silva18
- Daniel M. Fass16
- Wen‐Ning Zhao16
- Surya A. Reis14
- Steven D. Sheridan13
- Debasis Patnaik12
- Li‐Huei Tsai12
- Ralph Mazitschek12
- Stuart L. Schreiber12
- Roy H. Perlis10
- Florence F. Wagner7
- Jacob M. Hooker7
- Krista M. Hennig7
- Chialin Cheng6
- Diane Lucente6
- Edward B. Holson6
- Jasmin Lalonde6
- Jon M. Madison6
- Balaram Ghosh5
- Begüm Alural5
- Bradford C. Dickerson5
- Douglas Barker5
- Eric J. Nestler5
- Ji‐Song Guan5
All papers
- A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles
Authors: Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Sarah Johnson, Nicholas Lyons, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Roger Hu, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Peyton Greenside, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub - Cell 2017 cited by 3,788
- The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
Authors: Justin Lamb, Emily Crawford, D. D. Peck, Joshua W. Modell, Irene C. Blat, Matthew J. Wrobel, Jim Lerner, Jean-Philippe Brunet, Aravind Subramanian, Kenneth N. Ross, Michael Reich, Haley Hieronymus, Guo Wei, Scott A. Armstrong, Stephen J. Haggarty, Paul A. Clemons, Ru Wei, Steven A. Carr, Eric S. Lander, Todd R. Golub - Science 2006 cited by 5,510
- HDAC2 negatively regulates memory formation and synaptic plasticity
Authors: Ji‐Song Guan, Stephen J. Haggarty, Emanuela Giacometti, Jan‐Hermen Dannenberg, Nadine F. Joseph, Jun Gao, Thomas J.F. Nieland, Ying Zhou, Xinyu Wang, Ralph Mazitschek, James E. Bradner, Ronald A. DePinho, Rudolf Jaenisch, Li-Huei Tsai - Nature 2009 cited by 1,653
- An epigenetic blockade of cognitive functions in the neurodegenerating brain
Authors: Johannes Gräff, Damien Rei, Ji‐Song Guan, Wenyuan Wang, Jinsoo Seo, Krista M. Hennig, Thomas J.F. Nieland, Daniel M. Fass, Patricia F. Kao, Martin C. Kahn, Susan C. Su, Alireza Samiei, Nadine F. Joseph, Stephen J. Haggarty, Ivana Delalle, Li‐Huei Tsai - Nature 2012 cited by 859
- Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission
Authors: Ralda Nehme, Emanuela Zuccaro, Sulagna Ghosh, Chenchen Li, J. L. Sherwood, Olli Pietiläinen, Lindy E. Barrett, Francesco Limone, Kathleen A. Worringer, Sravya Kommineni, Ying Zang, Davide Cacchiarelli, Alex Meissner, Rolf Adolfsson, Stephen J. Haggarty, Jon M. Madison, Matthias Muller, Paola Arlotta, Zhanyan Fu, Guoping Feng, Kevin Eggan - Cell Reports 2018 cited by 276
- HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease
Authors: Ping‐Chieh Pao, Debasis Patnaik, L. Ashley Watson, Fan Gao, Ling Pan, Jun Wang, Chinnakkaruppan Adaikkan, Jay Penney, Hugh P. Cam, Wen‐Chin Huang, Lorena Pantano, Audrey Lee, Alexi Nott, Trongha Phan, Elizabeta Gjoneska, Sara Elmsaouri, Stephen J. Haggarty, Li‐Huei Tsai - Nature Communications 2020 cited by 209
- Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
Authors: M. Catarina Silva, Fleur M. Ferguson, Quan-Ying Cai, Katherine A. Donovan, Ghata Nandi, Debasis Patnaik, Tinghu Zhang, Hai‐Tsang Huang, Diane Lucente, Bradford C. Dickerson, Timothy J. Mitchison, Eric S. Fischer, Nathanael S. Gray, Stephen J. Haggarty - eLife 2019 cited by 274
- Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease
Authors: Mark Kilgore, Courtney A. Miller, Daniel M. Fass, Krista M. Hennig, Stephen J. Haggarty, J. David Sweatt, Gavin Rumbaugh - Neuropsychopharmacology 2009 cited by 725
- ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
Authors: Kathryn R. Bowles, M. Catarina Silva, Kristen Whitney, Taylor Bertucci, Joshua Berlind, Jesse D. Lai, Jacob C. Garza, Nathan C. Boles, Sidhartha Mahali, Kevin H. Strang, Jacob Marsh, Cynthia Chen, Derian A. Pugh, Yiyuan Liu, Ronald E. Gordon, Susan K. Goderie, Rebecca Chowdhury, Steven Lotz, Keith Lane, John F. Crary, Stephen J. Haggarty, Celeste M. Karch, Justin K. Ichida, Alison Goate, Sally Temple - Cell 2021 cited by 169
- Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen
Authors: Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty, Randall W. King, Stuart L. Schreiber, Timothy J. Mitchison - Science 1999 cited by 1,739
- Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
Authors: Stephen J. Haggarty, Kathryn M. Koeller, Jason Chun Yu Wong, Christina M. Grozinger, Stuart L. Schreiber - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 1,058
- Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons
Authors: M. Catarina Silva, Ghata Nandi, Sharon Tentarelli, Ian Gurrell, Tanguy Jamier, Diane Lucente, Bradford C. Dickerson, Dean G. Brown, Nicholas J. Brandon, Stephen J. Haggarty - Nature Communications 2020 cited by 158
- Chemical phylogenetics of histone deacetylases
Authors: James E. Bradner, Nathan West, Melissa L. Grachan, Edward F. Greenberg, Stephen J. Haggarty, Tandy Warnow, Ralph Mazitschek - Nature Chemical Biology 2010 cited by 728
- A psychiatric disease-related circular RNA controls synaptic gene expression and cognition
Authors: Amber Zimmerman, Alexander Hafez, Stephen Amoah, Brian A. Rodriguez, Michela Dell’Orco, Evelyn Lozano, Brigham J. Hartley, Begüm Alural, Jasmin Lalonde, Praveen Chander, Maree J. Webster, Roy H. Perlis, Kristen Brennand, Stephen J. Haggarty, Jason P. Weick, Nora I. Perrone‐Bizzozero, Jonathan L. Brigman, Nikolaos Mellios - Molecular Psychiatry 2020 cited by 167
- MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling
Authors: Nikolaos Mellios, Danielle Feldman, Steven D. Sheridan, Jacque Pak Kan Ip, Showming Kwok, Stephen Amoah, Barry P. Rosen, Brian A. Rodriguez, Ben Crawford, Radha Swaminathan, Stephanie Chou, Yun Li, Mark N. Ziats, Carl Ernst, Rudolf Jaenisch, Stephen J. Haggarty, Mriganka Sur - Molecular Psychiatry 2017 cited by 311
- Small molecule regulators of microRNAs identified by high-throughput screen coupled with high-throughput sequencing
Authors: Lien D. Nguyen, Zhiyun Wei, M. Catarina Silva, Sergio Barberán-Soler, Jiarui Zhang, Rosalia Rabinovsky, Christina Muratore, Jonathan M. S. Stricker, Colin Hortman, Tracy L. Young‐Pearse, Stephen J. Haggarty, Anna M. Krichevsky - Nature Communications 2023 cited by 52
- A polygenic burden of rare disruptive mutations in schizophrenia
Authors: Shaun Purcell, Jennifer L. Moran, Menachem Fromer, Douglas M. Ruderfer, Nadia Solovieff, Panos Roussos, Colm Ó'Dúshláine, Kimberly Chambert, Sarah E. Bergen, Anna K. Kähler, Laramie E. Duncan, Eli Stahl, Giulio Genovese, Esperanza Fernández, Mark O. Collins, Noboru H. Komiyama, Jyoti S. Choudhary, Patrik K. E. Magnusson, Eric Banks, Khalid Shakir, Kiran Garimella, Tim Fennell, Mark A. DePristo, Seth G. N. Grant, Stephen J. Haggarty, Stacey Gabriel, Edward M. Scolnick, Eric S. Lander, Christina M. Hultman, Patrick F. Sullivan, Steven A. McCarroll, Pamela Sklar - Nature 2014 cited by 1,461
- CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors
Authors: Aarathi Sugathan, Marta Biagioli, Christelle Golzio, Serkan Erdin, Ian Blumenthal, Poornima Manavalan, Ashok Ragavendran, Harrison Brand, Diane Lucente, Judith H. Miles, Steven D. Sheridan, Alexei Stortchevoi, Manolis Kellis, Stephen J. Haggarty, Nicholas Katsanis, James F. Gusella, Michael E. Talkowski - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 353
- A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies
Authors: Celeste M. Karch, Aimee W. Kao, Anna Karydas, Khadijah Onanuga, Rita Martinez, Andrea R. Argouarch, Chao Wang, Cindy Huang, Peter Sohn, Kathryn R. Bowles, Salvatore Spina, M. Catarina Silva, Jacob Marsh, Simon Hsu, Derian A. Pugh, Nupur Ghoshal, Joanne Norton, Yadong Huang, Suzee E. Lee, William W. Seeley, Panagiotis Theofilas, Lea T. Grinberg, Fermín Moreno, Kathryn McIlroy, Bradley F. Boeve, Nigel J. Cairns, John F. Crary, Stephen J. Haggarty, Justin K. Ichida, Kenneth S. Kosik, Bruce L. Miller, Li Gan, Alison Goate, Sally Temple, Carolina Alquézar, Kathryn R. Bowles, David Butler, John F. Crary, Li Gan, Alison Goate, Stephen J. Haggarty, Israel Hernández, Valerie Hennes, Cindy Huang, Justin K. Ichida, Martin Kampmann, Aimee W. Kao, Celeste M. Karch, Anna Karydas, Kenneth S. Kosik, Rita Martinez, Khadijah Onanuga, M. Catarina Silva, Sally Temple, Chao Wang, M. Catarina Silva, Sally Temple, Sally Temple, Chao Wang - Stem Cell Reports 2019 cited by 126
- A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes
Authors: Ping‐Chieh Pao, Jinsoo Seo, Audrey Lee, Oleg Kritskiy, Debasis Patnaik, Jay Penney, Ravikiran M. Raju, Ute Geigenmuller, M. Catarina Silva, Diane Lucente, James F. Gusella, Bradford C. Dickerson, Anjanet Loon, Margaret X. Yu, Michael Bula, Melody Yu, Stephen J. Haggarty, Li‐Huei Tsai - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 cited by 59
- An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons
Authors: Monica Boselli, Byung‐Hoon Lee, Jessica Robert, Miguel A. Prado, Sang‐Won Min, Chialin Cheng, M. Catarina Silva, Changhyun Seong, Suzanne Elsasser, Ketki M. Hatle, Timothy C. Gahman, Steven P. Gygi, Stephen J. Haggarty, Li Gan, Randall W. King, Daniel Finley - Journal of Biological Chemistry 2017 cited by 145
- Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation
Authors: Jason Rihel, David A. Prober, Anthony C. Arvanites, Kelvin Lam, Steven Zimmerman, Sumin Jang, Stephen J. Haggarty, David Kokel, Lee L. Rubin, Randall T. Peterson, Alexander F. Schier - Science 2010 cited by 801
- Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling
Authors: Yingwei Mao, Xuecai Ge, Christopher L. Frank, Jon M. Madison, Angela N. Koehler, Mary Kathryn Doud, Carlos Tassa, Erin M. Berry, Takahiro Soda, Karun K. Singh, Travis L. Biechele, Tracey L. Petryshen, Randall T. Moon, Stephen J. Haggarty, Li-Huei Tsai - Cell 2009 cited by 783
- Discovery and Optimization of Tau Targeted Protein Degraders Enabled by Patient Induced Pluripotent Stem Cells-Derived Neuronal Models of Tauopathy
Authors: M. Catarina Silva, Ghata Nandi, Katherine A. Donovan, Quan-Ying Cai, Bethany C. Berry, Radosław P. Nowak, Eric S. Fischer, Nathanael S. Gray, Fleur M. Ferguson, Stephen J. Haggarty - Frontiers in Cellular Neuroscience 2022 cited by 49
