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Scott A. Armstrong

Active 1991–2026

Also published as
Scott A Armstrong
156
Papers
37,962
Citations
91
h-index
148
i10-index

Citations

Citations per year for Scott A. Armstrong1980: 1 citations1984: 1 citations1985: 1 citations1987: 1 citations1991: 7 citations1992: 7 citations1993: 17 citations1994: 31 citations1995: 30 citations1996: 37 citations1997: 32 citations1998: 32 citations1999: 32 citations2000: 34 citations2001: 37 citations2002: 54 citations2003: 91 citations2004: 90 citations2005: 112 citations2006: 115 citations2007: 236 citations2008: 368 citations2009: 362 citations2010: 389 citations2011: 414 citations2012: 480 citations2013: 483 citations2014: 527 citations2015: 572 citations2016: 634 citations2017: 591 citations2018: 502 citations2019: 1,541 citations2020: 1,619 citations2021: 1,504 citations2022: 1,100 citations2023: 902 citations2024: 1,516 citations2025: 797 citations2026: 13 citations1981–1983: no citations, so these years are not shown1986: no citations, so this year is not shown1988–1990: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 6,100 citing papers, 33.1% of this breakdownChina: 2,156 citing papers, 11.7% of this breakdownUnited Kingdom: 1,173 citing papers, 6.4% of this breakdownGermany: 1,155 citing papers, 6.3% of this breakdownItaly: 618 citing papers, 3.3% of this breakdownCanada: 599 citing papers, 3.2% of this breakdownFrance: 593 citing papers, 3.2% of this breakdownAustralia: 517 citing papers, 2.8% of this breakdownJapan: 513 citing papers, 2.8% of this breakdownNetherlands: 468 citing papers, 2.5% of this breakdownSpain: 448 citing papers, 2.4% of this breakdownSwitzerland: 347 citing papers, 1.9% of this breakdown
0%33.1%Other 20.4%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology52%
  • Medicine35.1%
  • Computer Science6.7%
  • Immunology and Microbiology2.7%
  • Neuroscience1%
  • Agricultural and Biological Sciences0.4%
  • Other2.1%

Topics

  • Acute Myeloid Leukemia Research5.9%
  • Epigenetics and DNA Methylation4.9%
  • Protein Degradation and Inhibitors3.4%
  • Bioinformatics and Genomic Networks3.3%
  • Computational Drug Discovery Methods3.1%
  • Histone Deacetylase Inhibitors Research2.4%
  • Other77%

Coauthors

All papers

Open in search
  1. The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

    Authors: Justin Lamb, Emily Crawford, D. D. Peck, Joshua W. Modell, Irene C. Blat, Matthew J. Wrobel, Jim Lerner, Jean-Philippe Brunet, Aravind Subramanian, Kenneth N. Ross, Michael Reich, Haley Hieronymus, Guo Wei, Scott A. Armstrong, Stephen J. Haggarty, Paul A. Clemons, Ru Wei, Steven A. Carr, Eric S. Lander, Todd R. Golub - Science 2006 cited by 5,510

  2. The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia

    Authors: Ghayas C. Issa, Ibrahim Aldoss, John F. DiPersio, Branko Cuglievan, Richard M. Stone, Martha Arellano, Michael J. Thirman, Manish R. Patel, David S. Dickens, Shalini Shenoy, Neerav Shukla, Hagop M. Kantarjian, Scott A. Armstrong, Florian Perner, Jennifer A. Perry, Galit Rosen, Rebecca G. Bagley, Michael L. Meyers, Peter Ordentlich, Yu Gu, Vinit Kumar, Steven G. Smith, Gerard M. McGeehan, Eytan M. Stein - Nature 2023 cited by 468

  3. MEN1 mutations mediate clinical resistance to menin inhibition

    Authors: Florian Perner, Eytan M. Stein, Daniela V. Wenge, Sukrit Singh, Jeonghyeon Kim, Athina Apazidis, Homa Rahnamoun, Disha Anand, Christian Marinaccio, Charlie Hatton, Yanhe Wen, Richard M. Stone, David Schaller, Shoron Mowla, Wenbin Xiao, Holly A. Gamlen, Aaron J. Stonestrom, Sonali Persaud, Elizabeth T. Ener, Jevon Cutler, John G. Doench, Gerard M. McGeehan, Andrea Volkamer, John D. Chodera, Radosław P. Nowak, Eric S. Fischer, Ross L. Levine, Scott A. Armstrong, Sheng F. Cai - Nature 2023 cited by 243

  4. A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

    Authors: Andrei V. Krivtsov, Kathryn Evans, Jayant Y. Gadrey, Benjamin K. Eschle, Charlie Hatton, Hannah J. Uckelmann, Kenneth N. Ross, Florian Perner, Sarah Naomi Olsen, Tara Pritchard, Lisa McDermott, Connor Jones, Duohui Jing, Ali Braytee, Diego Chacon Fajardo, Eric J. Earley, Brian M. McKeever, David A. Claremon, Andrew J. Gifford, Heather Lee, Beverly A. Teicher, John E. Pimanda, Dominik Beck, Jennifer A. Perry, Malcolm A. Smith, Gerard M. McGeehan, Richard B. Lock, Scott A. Armstrong - Cancer Cell 2019 cited by 449

  5. The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia

    Authors: Eytan M. Stein, Guillermo Garcia‐Manero, David A. Rizzieri, Raoul Tibes, Jesús G. Berdeja, Michael R. Savona, Mojca Jongen-Lavrenic, Jessica K. Altman, Blythe Thomson, Stephen J. Blakemore, Scott R. Daigle, Nigel J. Waters, A. Benjamin Suttle, Alicia Clawson, Roy M. Pollock, Andrei V. Krivtsov, Scott A. Armstrong, Jorge DiMartino, Eric Hedrick, Bob Löwenberg, Martin S. Tallman - Blood 2018 cited by 457

  6. A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies

    Authors: Steffen Boettcher, Peter G. Miller, Rohan Sharma, Marie McConkey, Matthew Leventhal, Andrei V. Krivtsov, Andrew O. Giacomelli, Waihay J. Wong, Jesi Kim, Sherry Chao, Kari J. Kurppa, Xiaoping Yang, Kirsten Milenkowic, Federica Piccioni, David E. Root, Frank G. Rücker, Yael Flamand, Donna Neuberg, R. Coleman Lindsley, Pasi A. Jänne, William C. Hahn, Tyler Jacks, Hartmut Döhner, Scott A. Armstrong, Benjamin L. Ebert - Science 2019 cited by 434

  7. Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

    Authors: Andrei V. Krivtsov, David Twomey, Zhaohui Feng, Matthew C. Stubbs, Yingzi Wang, Joerg Faber, Jason Levine, Jing Wang, William C. Hahn, D. Gary Gilliland, Todd R. Golub, Scott A. Armstrong - Nature 2006 cited by 1,541

  8. Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition

    Authors: Sergio Crespo‐Garcia, Pamela R. Tsuruda, Agnieszka Dejda, Rathi D. Ryan, Frédérik Fournier, S. Chaney, Frédérique Pilon, Taner Dogan, Gaël Cagnone, Priyanka Patel, Manuel Buscarlet, Sonali Dasgupta, Gabrielle Girouard, Surabhi Rao, Ariel M. Wilson, Robert O’Brien, Rachel Juneau, Vera Guber, Alexandre Dubrac, Christian Beauséjour, Scott A. Armstrong, Frédérick A. Mallette, Christopher B. Yohn, Jean‐Sébastien Joyal, Dan Marquess, Pedro J. Beltran, Przemysław Sapieha - Cell Metabolism 2021 cited by 178

  9. MLL translocations, histone modifications and leukaemia stem-cell development

    Authors: Andrei V. Krivtsov, Scott A. Armstrong - Nature reviews. Cancer 2007 cited by 1,257

  10. Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

    Authors: Hannah J. Uckelmann, Elena Haarer, Reina Takeda, Eric Wong, Charlie Hatton, Christian Marinaccio, Florian Perner, Masooma Rajput, Noa J.C. Antonissen, Yanhe Wen, Lu Yang, Lorenzo Brunetti, Chun‐Wei Chen, Scott A. Armstrong - Cancer Discovery 2022 cited by 126

  11. The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML

    Authors: Emily Heikamp, Jill A. Henrich, Florian Perner, Eric Wong, Charlie Hatton, Yanhe Wen, Sonali P. Barwe, Anilkumar Gopalakrishnapillai, Haiming Xu, Hannah J. Uckelmann, Sumiko Takao, Yaniv Kazansky, Yana Pikman, Gerard M. McGeehan, E. Anders Kolb, Alex Kentsis, Scott A. Armstrong - Blood 2021 cited by 141

  12. Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia

    Authors: Hannah J. Uckelmann, Stephanie M. Kim, Eric Wong, Charlie Hatton, Hugh Giovinazzo, Jayant Y. Gadrey, Andrei V. Krivtsov, Frank G. Rücker, Konstanze Döhner, Gerard M. McGeehan, Ross L. Levine, Lars Bullinger, George S. Vassiliou, Scott A. Armstrong - Science 2020 cited by 271

  13. Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia

    Authors: Michael W.M. Kühn, E Song, Zhaohui Feng, Amit Sinha, Chun‐Wei Chen, Aniruddha J. Deshpande, Monica Cusan, Noushin Farnoud, Annalisa Mupo, Carolyn Grove, Richard P. Koche, James E. Bradner, Elisa de Stanchina, George S. Vassiliou, Takayuki Hoshii, Scott A. Armstrong - Cancer Discovery 2016 cited by 253

  14. Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

    Authors: Gabriele Casirati, Andrea Cosentino, Adele Mucci, Mohammed S. Mahmoud, Iratxe Ugarte Zabala, Jing Zeng, Scott B. Ficarro, Denise Klatt, Christian Brendel, Alessandro Rambaldi, Jerome Ritz, Jarrod A. Marto, Danilo Pellin, Daniel E. Bauer, Scott A. Armstrong, Pietro Genovese - Nature 2023 cited by 102

  15. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

    Authors: Scott A. Armstrong, Jane Staunton, Lewis B. Silverman, Rob Pieters, Monique L. den Boer, Mark D. Minden, Stephen E. Sallan, Eric S. Lander, Todd R. Golub, Stanley J. Korsmeyer - Nature Genetics 2001 cited by 1,719

  16. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

    Authors: Michael Certo, Victoria Del Gaizo Moore, Mari Nishino, Guo Wei, Stanley J. Korsmeyer, Scott A. Armstrong, Anthony Letai - Cancer Cell 2006 cited by 1,261

  17. MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L

    Authors: Kathrin M. Bernt, Nan Zhu, Amit Sinha, Sridhar Vempati, Joerg Faber, Andrei V. Krivtsov, Zhaohui Feng, Natalie Punt, Amanda J. Daigle, Lars Bullinger, Roy M. Pollock, Victoria M. Richon, Andrew L. Kung, Scott A. Armstrong - Cancer Cell 2011 cited by 893

  18. A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition

    Authors: Yadira M. Soto‐Feliciano, Francisco J. Sánchez‐Rivera, Florian Perner, Douglas Barrows, Edward R. Kastenhuber, Yu-Jui Ho, Thomas Carroll, Yijun Xiong, Disha Anand, Alexey A. Soshnev, Leah Gates, Mary C. Beytagh, David Cheon, Shengqing Gu, X. Shirley Liu, Andrei V. Krivtsov, Maximiliano Meneses, Elisa de Stanchina, Richard M. Stone, Scott A. Armstrong, Scott W. Lowe, C. David Allis - Cancer Discovery 2022 cited by 81

  19. ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia

    Authors: Liling Wan, Hong Wen, Yuanyuan Li, Jie Lyu, Yuanxin Xi, Takayuki Hoshii, Julia K. Joseph, Xiaolu Wang, Yong‐Hwee Eddie Loh, Michael A. Erb, Amanda L. Souza, James E. Bradner, Li Shen, Wei Li, Haitao Li, C. David Allis, Scott A. Armstrong, Xiaobing Shi - Nature 2017 cited by 295

  20. Mediator kinase inhibition further activates super-enhancer-associated genes in AML

    Authors: Henry E. Pelish, Brian B. Liau, I Niţulescu, Anupong Tangpeerachaikul, Zachary C. Poss, Diogo H. Da Silva, Brittany Caruso, Alexander Arefolov, Olugbeminiyi Fadeyi, Amanda L. Christie, Karrie Du, Deepti Banka, Elisabeth V. Schneider, A. Jestel, Ge Zou, Chong Si, Christopher C. Ebmeier, Roderick T. Bronson, Andrei V. Krivtsov, Andrew G. Myers, Nancy E. Kohl, Andrew L. Kung, Scott A. Armstrong, Madeleine E. Lemieux, Dylan J. Taatjes, Matthew D. Shair - Nature 2015 cited by 405

  21. Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

    Authors: Scott R. Daigle, Edward J. Olhava, Carly A. Therkelsen, Christina R. Majer, Christopher J. Sneeringer, Jeffrey Song, L. Danielle Johnston, Margaret Porter Scott, J. Joshua Smith, Yonghong Xiao, Lei Jin, Kevin W. Kuntz, Richard Chesworth, Mikel P. Moyer, Kathrin M. Bernt, Jen‐Chieh Tseng, Andrew L. Kung, Scott A. Armstrong, Robert A. Copeland, Victoria M. Richon, Roy M. Pollock - Cancer Cell 2011 cited by 934

  22. Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma

    Authors: Gerard L. Brien, David Remillard, Junwei Shi, Matthew L. Hemming, Jonathon Chabon, Kieran Wynne, Eugène Dillon, Gerard Cagney, Guido van Mierlo, Marijke Baltissen, Michiel Vermeulen, Jun Qi, Stefan Fröhling, Nathanael S. Gray, James E. Bradner, Christopher R. Vakoc, Scott A. Armstrong - eLife 2018 cited by 216

  23. FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

    Authors: Zuzana Tóthová, Ramya Kollipara, Brian J.P. Huntly, Benjamin H. Lee, Diego H. Castrillón, Dana E. Cullen, Elizabeth McDowell, Suzan Lazo-Kallanian, Ifor R. Williams, Christopher Sears, Scott A. Armstrong, Emmanuelle Passegué, Ronald A. DePinho, D. Gary Gilliland - Cell 2007 cited by 1,559

  24. Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins

    Authors: Stanley Chun-Wei Lee, Heidi Dvinge, Eun Hee Kim, Hana Cho, Jean‐Baptiste Micol, Young Rock Chung, Benjamin H. Durham, Akihide Yoshimi, Young Joon Kim, Michaël Thomas, Camille Lobry, Chun‐Wei Chen, Alessandro Pastore, Justin Taylor, Xujun Wang, Andrei V. Krivtsov, Scott A Armstrong, James Palacino, Silvia Buonamici, Peter G. Smith, Robert K. Bradley, Omar Abdel‐Wahab - Nature Medicine 2016 cited by 354