Stephen J. O’Keefe
Active 1974–2024
- 91
- Papers
- 18,328
- Citations
- 75
- h-index
- 90
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine46.1%
- Biochemistry, Genetics and Molecular Biology38%
- Nursing6.2%
- Immunology and Microbiology3.6%
- Agricultural and Biological Sciences1.2%
- Computer Science1%
- Other3.9%
Topics
- Gut microbiota and health9.1%
- Cancer Immunotherapy and Biomarkers5.5%
- Diet and metabolism studies3.5%
- Bladder and Urothelial Cancer Treatments2.1%
- Clinical Nutrition and Gastroenterology2%
- Signaling Pathways in Disease1.8%
- Other76%
Coauthors
- Edward A. O’Neill9
- Kosei Hasegawa9
- Nicoletta Colombo9
- Domenica Lorusso8
- Annette Wilson7
- Soeren Ocvirk7
- Betsy Frantz6
- Ronnie Shapira‐Frommer6
- Ana Oaknin5
- Dennis M. Zaller5
- Jalid Sehouli5
- James P. DeLany5
- Jia V. Li5
- Kan Li5
- Palle Bekker Jeppesen5
- Anna Rolando4
- Bradley J. Monk4
- Catherine E. Fitzgerald4
- Coraline Dubot4
- Eduardo Yañez4
- Giovanna Scapin4
- H. Rex Gaskins4
- Janey N. Parsons4
- Junhai Ou4
All papers
- Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer
Authors: Nicoletta Colombo, Coraline Dubot, Domenica Lorusso, M. Valeria Cáceres, Kosei Hasegawa, Ronnie Shapira‐Frommer, Krishnansu S. Tewari, Pamela Salman, Edwin Hoyos Usta, Eduardo Yañez, Mahmut Gümüş, Mivael Olivera Hurtado de Mendoza, Vanessa Samouëlian, Vincent Castonguay, Arkhipov Alexander, Sarper Toker, Kan Li, Stephen J. O’Keefe, Bradley J. Monk - New England Journal of Medicine 2021 cited by 992
- Antitumor activity and safety of pembrolizumab in patients with advanced recurrent ovarian cancer: results from the phase II KEYNOTE-100 study
Authors: Ursula A. Matulonis, Ronnie Shapira‐Frommer, Alessandro D. Santin, Alla Lisyanskaya, Sandro Pignata, Ignace Vergote, Francesco Raspagliesi, Gabe S. Sonke, Michael J. Birrer, Diane Provencher, Jalid Sehouli, Nicoletta Colombo, Antonio González-Martı́n, Ana Oaknin, Petronella B. Ottevanger, Vilius Rudaitis, Kianoosh Katchar, Huita Wu, Stephen J. O’Keefe, Jane Ruman, Jonathan A. Ledermann - Annals of Oncology 2019 cited by 840
- Diet, microorganisms and their metabolites, and colon cancer
Authors: Stephen J. O’Keefe - Nature Reviews Gastroenterology & Hepatology 2016 cited by 1,088
- First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study
Authors: Arjun Vasant Balar, Daniel Castellano, Peter H. O’Donnell, Petros Grivas, Jacqueline Vuky, Thomas Powles, Elizabeth R. Plimack, Noah M. Hahn, Ronald de Wit, Lei Pang, Mary J. Savage, Rodolfo F. Perini, Stephen J. O’Keefe, Dean F. Bajorin, Joaquim Bellmunt - The Lancet Oncology 2017 cited by 1,342
- Fat, fibre and cancer risk in African Americans and rural Africans
Authors: Stephen J. O’Keefe, Jia V. Li, Leo Lahti, Junhai Ou, Franck Carbonero, Khaled Mohammed, Joram M. Posma, James Kinross, Elaine Wahl, Elizabeth H. Ruder, Kishore Vipperla, Vasudevan G. Naidoo, Lungile Mtshali, Sebastian Tims, Philippe G. Puylaert, James P. DeLany, Alyssa M. Krasinskas, Ann C. Benefiel, Hatem Kaseb, Keith Newton, Jeremy K. Nicholson, Willem M. de Vos, H. Rex Gaskins, Erwin G. Zoetendal - Nature Communications 2015 cited by 968
- Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial
Authors: Domenica Lorusso, Yang Xiang, Kosei Hasegawa, Giovanni Scambia, Manuel Leiva, Pier Ramos-Elías, Alejandro Acevedo, Vladyslav Sukhin, Noelle Cloven, Andrea Juliana Gomes, Fernando Contreras Mejía, Ari Reiss, Ali̇ Ayhan, Jung‐Yun Lee, Valeriya Saevets, Flora Zagouri, Lucy Gilbert, Jalid Sehouli, Ekkasit Tharavichitkul, Kristina Lindemann, Roberta Lazzari, Chih‐Long Chang, Rudolf Lampé, Hong Zhu, Ana Oaknin, Melissa Christiaens, Stephan Polterauer, Tomoka Usami, Kan Li, Karin Yamada, Sarper Toker, Stephen J. O’Keefe, Sandro Pignata, Linda Duska - The Lancet 2024 cited by 349
- First-Line Pembrolizumab + Chemotherapy Versus Placebo + Chemotherapy for Persistent, Recurrent, or Metastatic Cervical Cancer: Final Overall Survival Results of KEYNOTE-826
Authors: Bradley J. Monk, Nicoletta Colombo, Krishnansu S. Tewari, Coraline Dubot, M. Valeria Cáceres, Kosei Hasegawa, Ronnie Shapira‐Frommer, Pamela Salman, Eduardo Yañez, Mahmut Gümüş, Mivael Olivera, Vanessa Samouëlian, Vincent Castonguay, А. В. Архипов, Cumhur Tekin, Kan Li, Stephen J. O’Keefe, Domenica Lorusso, on behalf of the KEYNOTE-826 Investigators - Journal of Clinical Oncology 2023 cited by 236
- Dietary fat, bile acid metabolism and colorectal cancer
Authors: Soeren Ocvirk, Stephen J. O’Keefe - Seminars in Cancer Biology 2020 cited by 251
- Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study
Authors: Gertrude Ecklu-Mensah, Candice Choo-Kang, Maria Gjerstad Maseng, Sonya Donato, Pascal Bovet, Bharathi Viswanathan, Kweku Bedu-Addo, Jacob Plange‐Rhule, Prince Oti Boateng, Terrence Forrester, Marie Williams, Estelle V. Lambert, Dale E. Rae, Nandipha Sinyanya, Amy Luke, Brian T. Layden, Stephen J. O’Keefe, Jack A. Gilbert, Lara R. Dugas - Nature Communications 2023 cited by 114
- Diet and the Human Gut Microbiome: An International Review
Authors: Annette Wilson, Kathryn R. Koller, Matsepo C. Ramaboli, Lucky T. Nesengani, Soeren Ocvirk, Caixia Chen, Christie A. Flanagan, Flora Sapp, Zoe T Merritt, Faheem Bhatti, Timothy K. Thomas, Stephen J. O’Keefe - Digestive Diseases and Sciences 2020 cited by 375
- Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans
Authors: Junhai Ou, Franck Carbonero, Erwin G. Zoetendal, James P. DeLany, Mei Wang, Keith Newton, H. Rex Gaskins, Stephen J. O’Keefe - American Journal of Clinical Nutrition 2013 cited by 645
- International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis
Authors: Alasdair Scott, James L. Alexander, Claire A Merrifield, David Cunningham, Christian Jobin, Robert Brown, John C. Alverdy, Stephen J. O’Keefe, H. Rex Gaskins, Julian Teare, Jun Yu, David J. Hughes, Hans Verstraelen, Jeremy P. Burton, Paul W. O’Toole, Daniel W Rosenberg, Julian R. Marchesi, James M Kinross - Gut 2019 cited by 275
- Pembrolizumab for advanced prostate adenocarcinoma: findings of the KEYNOTE-028 study
Authors: Aaron R. Hansen, Christophe Massard, Patrick A. Ott, Naomi B. Haas, Juanita Lopez, Samuel Ejadi, John M. Wallmark, Bhumsuk Keam, Jean‐Pierre Delord, Rahul Aggarwal, M. Gould, Peng Yang, Stephen J. O’Keefe, Sarina A. Piha‐Paul - Annals of Oncology 2018 cited by 367
- Teduglutide Reduces Need for Parenteral Support Among Patients With Short Bowel Syndrome With Intestinal Failure
Authors: Palle Bekker Jeppesen, M. Pertkiewicz, Bernard Messing, Kishore Iyer, Douglas L. Seidner, Stephen J. O’Keefe, Alastair Forbes, Hartmut Heinze, B. Joelsson - Gastroenterology 2012 cited by 491
- Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 trial
Authors: Domenica Lorusso, Yang Xiang, Kosei Hasegawa, Giovanni Scambia, Manuel Leiva, Pier Ramos-Elías, Alejandro Acevedo, Jakub Cvek, Leslie M. Randall, Andrea Juliana Gomes, Fernando Contreras Mejía, Limor Helpman, Hüseyin Akıllı, Jung‐Yun Lee, Valeriya Saevets, Flora Zagouri, Lucy Gilbert, Jalid Sehouli, Ekkasit Tharavichitkul, Kristina Lindemann, Nicoletta Colombo, Chih‐Long Chang, Markéta Bednaříková, Hong Zhu, Ana Oaknin, Melissa Christiaens, Edgar Petru, Tomoka Usami, Peng Liu, Karin Yamada, Sarper Toker, Stephen J. O’Keefe, Sandro Pignata, Linda Duska - The Lancet 2024 cited by 161
- ENGOT-en11/GOG-3053/KEYNOTE-B21: a randomised, double-blind, phase III study of pembrolizumab or placebo plus adjuvant chemotherapy with or without radiotherapy in patients with newly diagnosed, high-risk endometrial cancer
Authors: Toon Van Gorp, David Cibula, Weiguo Lv, Floor Backes, Fırat Ortaç, K. Hasegawa, Kristina Lindemann, Antonella Savarese, Annouschka Laenen, Y.M. Kim, Lisa M. Bodnar, M-P Barretina-Ginesta, L. Gilbert, Bhavana Pothuri, Xiaojun Chen, Marcelo B.S. Flores, Tally Levy, N. Colombo, Christos Papadimitriou, Tommy Buchanan, L.C. Hanker, Gemma Eminowicz, L Rob, D. Black, Jasmine Lichfield, Gen Lin, Robert Orlowski, Stephen J. O’Keefe, Alain Lortholary, Brian M. Slomovitz - Annals of Oncology 2024 cited by 82
- The association between dietary fibre deficiency and high-income lifestyle-associated diseases: Burkitt's hypothesis revisited
Authors: Stephen J. O’Keefe - The Lancet. Gastroenterology & hepatology 2019 cited by 185
- Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome
Authors: Palle Bekker Jeppesen, Richard Gilroy, M. Pertkiewicz, Johane P. Allard, Bernard Messing, Stephen J. O’Keefe - Gut 2011 cited by 451
- Long-Term Teduglutide for the Treatment of Patients With Intestinal Failure Associated With Short Bowel Syndrome
Authors: Lauren K. Schwartz, Stephen J. O’Keefe, Ken Fujioka, Simon Gabe, Georg Lamprecht, Ulrich‐Frank Pape, Benjamin Li, Nader N. Youssef, Palle Bekker Jeppesen - Clinical and Translational Gastroenterology 2016 cited by 218
- Pembrolizumab or Placebo Plus Chemotherapy With or Without Bevacizumab for Persistent, Recurrent, or Metastatic Cervical Cancer
Authors: Krishnansu S. Tewari, Nicoletta Colombo, Bradley J. Monk, Coraline Dubot, M. Valeria Cáceres, Kosei Hasegawa, Ronnie Shapira‐Frommer, Pamela Salman, Eduardo Yáñez, Mahmut Gümüş, Mivael Olivera Hurtado de Mendoza, Vanessa Samouëlian, Vincent Castonguay, Alexander Arkhipov, Cumhur Tekin, Kan Li, Sarper Toker, Stephen J. O’Keefe, Domenica Lorusso - JAMA Oncology 2023 cited by 59
- A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer
Authors: Soeren Ocvirk, Annette Wilson, Joram M. Posma, Jia V. Li, Kathryn R. Koller, Gretchen Day, Christie A. Flanagan, Jill Evon Otto, Pam E Sacco, Frank Sacco, Flora Sapp, Amy Wilson, Keith Newton, Faye M. Brouard, James P. DeLany, Marissa Behnning, Corynn Appolonia, Devavrata Soni, Faheem Bhatti, Barbara A. Methé, Adam Fitch, Alison Morris, H. Rex Gaskins, James Kinross, Jeremy K. Nicholson, Timothy K. Thomas, Stephen J. O’Keefe - American Journal of Clinical Nutrition 2019 cited by 84
- Influence of Bile Acids on Colorectal Cancer Risk: Potential Mechanisms Mediated by Diet-Gut Microbiota Interactions
Authors: Soeren Ocvirk, Stephen J. O’Keefe - Current Nutrition Reports 2017 cited by 171
- Short Bowel Syndrome and Intestinal Failure: Consensus Definitions and Overview
Authors: Stephen J. O’Keefe, Alan L. Buchman, Thomas Fishbein, Khursheed N. Jeejeebhoy, Palle Bekker Jeppesen, Jonathan Shaffer - Clinical Gastroenterology and Hepatology 2006 cited by 513
- Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer
Authors: Matsepo C. Ramaboli, Soeren Ocvirk, Mohammadali Khan Mirzaei, B.L. Eberhart, Maria Valdivia‐Garcia, Amira Metwaly, Klaus Neuhaus, Gareth J. Barker, Jing Ru, Lucky T. Nesengani, D. Mahdi-Joest, Annette Wilson, Sikhumbule K. Joni, D. C. Layman, Jiamin Zheng, Raju K. Mandal, Qing Chen, Miriam R. Perez, Suereta Fortuin, Benjamin Gaunt, David S. Wishart, Barbara A. Methé, Dirk Haller, Jia V. Li, Li Deng, Rina Swart, Stephen J. O’Keefe - Nature Communications 2024 cited by 41
