Stephen Neidle
Active 1972–2025
- 149
- Papers
- 31,059
- Citations
- 101
- h-index
- 144
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology73.8%
- Medicine12.5%
- Chemistry4.3%
- Computer Science2.2%
- Materials Science1.5%
- Pharmacology, Toxicology and Pharmaceutics1.3%
- Other4.4%
Topics
- DNA and Nucleic Acid Chemistry20.1%
- Advanced biosensing and bioanalysis techniques16.3%
- RNA Interference and Gene Delivery10.1%
- RNA and protein synthesis mechanisms6.7%
- Metal complexes synthesis and properties2%
- Bacteriophages and microbial interactions1.7%
- Other43.1%
Coauthors
- Gary N. Parkinson26
- Anthony P. Reszka19
- Shozeb Haider18
- W. David Wilson18
- Mekala Gunaratnam15
- Lloyd R. Kèlland11
- Martin A. Read9
- Sharon Gowan9
- Terence C. Jenkins9
- David W. Boykin7
- Helen M. Berman7
- Shankar Balasubramanian7
- Stephan A. Ohnmacht7
- Alan K. Todd6
- Christoph Schultes6
- Farial A. Tanious6
- Jane V. Skelly6
- Ahmed A. Ahmed5
- Charles A. Laughton5
- David E. Thurston5
- Gavin W. Collie5
- Laurence H. Hurley5
- R. John Harrison5
- Ramón Vilar5
All papers
- Quadruplex DNA: sequence, topology and structure
Authors: Sarah Burge, Gary N. Parkinson, Pascale Hazel, Alan K. Todd, Stephen Neidle - Nucleic Acids Research 2006 cited by 2,394
- Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Authors: Shankar Balasubramanian, Laurence H. Hurley, Stephen Neidle - Nature Reviews Drug Discovery 2011 cited by 1,699
- Crystal structure of parallel quadruplexes from human telomeric DNA
Authors: Gary N. Parkinson, Michael P. H. Lee, Stephen Neidle - Nature 2002 cited by 2,038
- Quadruplex nucleic acids as targets for anticancer therapeutics
Authors: Stephen Neidle - Nature Reviews Chemistry 2017 cited by 459
- Quadruplex Nucleic Acids as Novel Therapeutic Targets
Authors: Stephen Neidle - Journal of Medicinal Chemistry 2016 cited by 584
- The G-Quadruplex-Interactive Molecule BRACO-19 Inhibits Tumor Growth, Consistent with Telomere Targeting and Interference with Telomerase Function
Authors: Angelika M. Burger, Fangping Dai, Christoph Schultes, Anthony P. Reszka, Michael J. Moore, John A. Double, Stephen Neidle - Cancer Research 2005 cited by 566
- Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule
Authors: Chiara Marchetti, Katherine G. Zyner, Stephan A. Ohnmacht, Mathew Robson, Shozeb Haider, Jennifer P. Morton, Giovanni Marsico, Tam Vo, Sarah Laughlin, Ahmed A. Ahmed, Gloria Di Vita, Ingrida Pazitna, Mekala Gunaratnam, Rachael J. Besser, Ana Clara Andrade, Seckou Diocou, Jeremy A. Pike, David Tannahill, R. Barbara Pedley, T.R. Jeffry Evans, W. David Wilson, Shankar Balasubramanian, Stephen Neidle - Journal of Medicinal Chemistry 2018 cited by 157
- Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound
Authors: Daekyu Sun, Brian Thompson, Brian E. Cathers, Miguel Salazar, Sean M. Kerwin, John O. Trent, Terence C. Jenkins, Stephen Neidle, Laurence H. Hurley - Journal of Medicinal Chemistry 1997 cited by 784
- Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter
Authors: Anh Tuân Phan, Vitaly Kuryavyi, Sarah Burge, Stephen Neidle, Dinshaw J. Patel - Journal of the American Chemical Society 2007 cited by 455
- Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors
Authors: Martin L. Read, R. John Harrison, Bárbara Romagnoli, Farial A. Tanious, Sharon H. Gowan, Anthony P. Reszka, W. David Wilson, Lloyd R. Kèlland, Stephen Neidle - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 484
- G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
Authors: Roberto Simone, Rubika Balendra, Thomas G. Moens, Elisavet Preza, Katherine Wilson, Amanda Heslegrave, Nathaniel S. Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L. Clayton, Mica T. M. Clarke, Marie‐Therese Konrad, Andrew J. Nicoll, Jamie S. Mitchell, Andrea Calvo, Adriano Chiò, Henry Houlden, James M. Polke, Mohamed A. Ismail, Chad E. Stephens, Tam Vo, Abdelbasset A. Farahat, W. David Wilson, David W. Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary N. Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M. Isaacs - EMBO Molecular Medicine 2017 cited by 222
- Loop-Length-Dependent Folding of G-Quadruplexes
Authors: Pascale Hazel, J Huppert, Shankar Balasubramanian, Stephen Neidle - Journal of the American Chemical Society 2004 cited by 483
- Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models
Authors: Ahmed A. Ahmed, Richard Angell, Sally Oxenford, Jenny Worthington, Nicole Williams, Naomi Barton, Thomas G. Fowler, Daniel E. O’Flynn, Mihiro Sunose, Matthew McConville, Tam Vo, W. David Wilson, Saadia A. Karim, Jennifer P. Morton, Stephen Neidle - ACS Medicinal Chemistry Letters 2020 cited by 57
- Structure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling
Authors: Ahmed A. Ahmed, Shuang Chen, Maria Roman-Escorza, Richard Angell, Sally Oxenford, Matthew McConville, Naomi Barton, Mihiro Sunose, Dan M. Neidle, Shozeb Haider, Tariq Arshad, Stephen Neidle - Scientific Reports 2024 cited by 27
- Human telomeric G‐quadruplex: The current status of telomeric G‐quadruplexes as therapeutic targets in human cancer
Authors: Stephen Neidle - FEBS Journal 2009 cited by 542
- G-quadruplex nucleic acids as therapeutic targets
Authors: Shankar Balasubramanian, Stephen Neidle - Current Opinion in Chemical Biology 2009 cited by 581
- Structure-Based Design and Evaluation of Naphthalene Diimide G-Quadruplex Ligands As Telomere Targeting Agents in Pancreatic Cancer Cells
Authors: Marialuisa Micco, Gavin W. Collie, Aaron G. Dale, Stephan A. Ohnmacht, Ingrida Pazitna, Mekala Gunaratnam, Anthony P. Reszka, Stephen Neidle - Journal of Medicinal Chemistry 2013 cited by 183
- Stabilization of G-Quadruplex DNA and Inhibition of Telomerase Activity by Square-Planar Nickel(II) Complexes
Authors: Julie Reed, Anna Arola‐Arnal, Stephen Neidle, Ramón Vilar - Journal of the American Chemical Society 2006 cited by 333
- A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer
Authors: Stephan A. Ohnmacht, Chiara Marchetti, Mekala Gunaratnam, Rachael J. Besser, Shozeb Haider, Gloria Di Vita, Helen L. Lowe, Maria Mellinas‐Gomez, Seckou Diocou, Mathew Robson, Jiřı́ Šponer, Barira Islam, RB Pedley, John A. Hartley, Stephen Neidle - Scientific Reports 2015 cited by 115
- A standard reference frame for the description of nucleic acid base-pair geometry
Authors: Wilma K. Olson, Manju Bansal, S.K. Burley, Richard E. Dickerson, Mark Gerstein, Stephen C. Harvey, Udo Heinemann, Xiang‐Jun Lu, Stephen Neidle, Zippora Shakked, Heinz Sklenar, Masashi Suzuki, Chang‐Shung Tung, Éric Westhof, Cynthia Wolberger, Helen M. Berman - Journal of Molecular Biology 2001 cited by 602
- Putative DNA Quadruplex Formation within the Human c-kit Oncogene
Authors: Sarah Rankin, Anthony P. Reszka, J Huppert, Mire Zloh, Gary N. Parkinson, Alan K. Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle - Journal of the American Chemical Society 2005 cited by 549
- Structural Basis of DNA Quadruplex Recognition by an Acridine Drug
Authors: N. Campbell, Gary N. Parkinson, Anthony P. Reszka, Stephen Neidle - Journal of the American Chemical Society 2008 cited by 315
- A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
Authors: Gavin W. Collie, Shozeb Haider, Stephen Neidle, Gary N. Parkinson - Nucleic Acids Research 2010 cited by 251
- Molecular Dynamics and Principal Components Analysis of Human Telomeric Quadruplex Multimers
Authors: Shozeb Haider, Gary N. Parkinson, Stephen Neidle - Biophysical Journal 2008 cited by 213
