Timothy W. Behrens
Active 1994–2022
- 93
- Papers
- 27,450
- Citations
- 84
- h-index
- 92
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University1.2%
- Inserm0.8%
- Brigham and Women's Hospital0.8%
- Karolinska Institutet0.7%
- Broad Institute0.7%
- National Institutes of Health0.7%
- Other95.1%
Fields
- Medicine49.9%
- Biochemistry, Genetics and Molecular Biology25.3%
- Immunology and Microbiology19.4%
- Neuroscience2.9%
- Computer Science0.8%
- Agricultural and Biological Sciences0.4%
- Other1.3%
Topics
- Systemic Lupus Erythematosus Research7.3%
- T-cell and B-cell Immunology6.2%
- Immune Cell Function and Interaction4.3%
- Alzheimer's disease research and treatments3.4%
- Genetic Associations and Epidemiology3%
- Rheumatoid Arthritis Research and Therapies2.6%
- Other73.2%
Coauthors
- Robert Graham39
- Peter K. Gregersen30
- Ward Ortmann30
- Patrick M. Gaffney20
- Lindsey A. Criswell19
- Emily C. Baechler13
- Tushar Bhangale13
- Kathy L. Moser12
- Michelle Petri12
- Franak Batliwalla11
- Michael F. Seldin10
- Annette T. Lee9
- Carl D. Langefeld9
- John B. Harley9
- Kimberly E. Taylor9
- Sharon A. Chung9
- Timothy J. Vyse9
- Geoffrey Hom7
- Joanne Nititham7
- Marta E. Alarcón‐Riquelme7
- Susan Manzi7
- Wentian Li7
- Annette Lee6
- Ann‐Christine Syvänen6
All papers
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
Authors: Yukinori Okada, Di Wu, Gosia Trynka, Towfique Raj, Chikashi Terao, Katsunori Ikari, Yuta Kochi, Koichiro Ohmura, Akari Suzuki, Shinji Yoshida, Robert Graham, Arun Manoharan, Ward Ortmann, Tushar Bhangale, Joshua C. Denny, Robert J. Carroll, Anne E. Eyler, Jeffrey D. Greenberg, Joel M. Kremer, Dimitrios A. Pappas, Lei Jiang, Jian Yin, Lingying Ye, Ding‐Feng Su, Jian Yang, Gang Xie, Ed Keystone, Harm-Jan Westra, Tõnu Esko, Andres Metspalu, Xuezhong Zhou, Namrata Gupta, Daniel B. Mirel, Eli A. Stahl, Dorothée Diogo, Jing Cui, Katherine P. Liao, Michael H. Guo, Keiko Myouzen, Takahisa Kawaguchi, Marieke J. H. Coenen, Piet L. C. M. van Riel, Mart A F J van de Laar, Henk‐Jan Guchelaar, T. Huizinga, Philippe Dieudé, Xavier Mariette, S. Louis Bridges, Alexandra Zhernakova, René E. M. Toes, Paul P. Tak, Corinne Miceli‐Richard, So‐Young Bang, Hye‐Soon Lee, Javier Martı́n, Miguel Á. González‐Gay, Luis Rodríguez‐Rodríguez, Solbritt Rantapää‐Dahlqvist, Lisbeth Ärlestig, Hyon K. Choi, Yoichiro Kamatani, Pilar Galán, Mark Lathrop, Steve Eyre, John Bowes, Anne Barton, Niek de Vries, Larry W. Moreland, Lindsey A. Criswell, Elizabeth W. Karlson, Atsuo Taniguchi, Ryo Yamada, Michiaki Kubo, Jun S. Liu, Sang‐Cheol Bae, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Soumya Raychaudhuri, Barbara E. Stranger, Philip L. De Jager, Lude Franke, Peter M. Visscher, Matthew A. Brown, Hisashi Yamanaka, Tsuneyo Mimori, Atsushi Takahashi, Huji Xu, Timothy W. Behrens, Katherine Siminovitch, Shigeki Momohara, Fumihiko Matsuda, Kazuhiko Yamamoto, Robert M. Plenge - Nature 2013 cited by 2,499
- Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
Authors: James Bentham, David Morris, Deborah S. Cunninghame Graham, Christopher L. Pinder, Philip Tombleson, Timothy W. Behrens, Javier Martı́n, Benjamin P. Fairfax, Julian C. Knight, Lingyan Chen, Joseph M. Replogle, Ann-Christine Syvänen, Lars Rönnblom, Robert Graham, Joan Wither, John D. Rioux, Marta E. Alarcón‐Riquelme, Timothy J. Vyse - Nature Genetics 2015 cited by 1,094
- A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
Authors: Diana Chang, Mike A. Nalls, Ingileif B. Hallgrímsdóttir, Julie Hunkapiller, Marcel van der Brug, Fang Cai, Geoffrey A. Kerchner, Gai Ayalon, Baris Bingol, Morgan Sheng, David A. Hinds, Timothy W. Behrens, Andrew Singleton, Tushar Bhangale, Robert Graham - Nature Genetics 2017 cited by 1,210
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
Authors: Thorlákur Jónsson, Jasvinder K. Atwal, Stacy Steinberg, Jón Snædal, Pálmi V. Jónsson, Sigurbjörn Björnsson, Hreinn Stefánsson, Patrick Sulem, Daníel F. Guðbjartsson, Janice Maloney, Kwame Hoyte, Amy Gustafson, Yichin Liu, Yanmei Lu, Tushar Bhangale, Robert Graham, Johanna Huttenlocher, Gyða Björnsdóttir, Ole A. Andreassen, Erik G. Jönsson, Aarno Palotie, Timothy W. Behrens, Ólafur Þ. Magnússon, Augustine Kong, Unnur Þorsteinsdóttir, Ryan J. Watts, Kāri Stefánsson - Nature 2012 cited by 1,745
- Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
Authors: Emily C. Baechler, Franak Batliwalla, George Karypis, Patrick M. Gaffney, Ward Ortmann, Karl J. Espe, Katherine B. Shark, William J. Grande, Karis M. H. Hughes, Vivek Kapur, Peter K. Gregersen, Timothy W. Behrens - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 2,244
- Transancestral mapping and genetic load in systemic lupus erythematosus
Authors: Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo‐Vásquez, Graciela S. Alarcón, Alejandra Babini, Vicente Baca, Anders Bengtsson, Guillermo Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luís J. Catoggio, Ricard Cervera, Jorge M. Cucho‐Venegas, Solbritt Rantapää‐Dahlqvist, Sandra D’Alfonso, Berta Martins da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emõke Endreffy, Jorge Antonio Esquivel‐Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes García, Ignacio García‐De La Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard Lauwerys, Quan‐Zhen Li, Marco A. Maradiaga‐Ceceña, Javier Martı́n, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro C. Miranda, J. F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego‐Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons‐Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey‐Goldman, John D. Reveille, Laurie Russell, José Mario Sabio, Carlos A. Aguilar‐Salinas, Hugo R. Scherbarth, R Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio Toloza, Lennart Truedsson, Teresa Tusié‐Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann‐Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens and 8 more - Nature Communications 2017 cited by 437
- STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus
Authors: Elaine F. Remmers, Robert M. Plenge, Annette T. Lee, Robert Graham, Geoffrey Hom, Timothy W. Behrens, Paul I. W. de Bakker, Julie Le, Hye‐Soon Lee, Franak Batliwalla, Wentian Li, Seth L. Masters, Matthew G. Booty, John P. Carulli, Leonid Padyukov, Lars Alfredsson, Lars Klareskog, Wei V. Chen, Christopher I. Amos, Lindsey A. Criswell, Michael F. Seldin, Daniel L. Kastner, Peter K. Gregersen - New England Journal of Medicine 2007 cited by 1,050
- Association of Systemic Lupus Erythematosus with C8orf13–BLK and ITGAM–ITGAX
Authors: Geoffrey Hom, Robert Graham, Barmak Modrek, Kimberly E. Taylor, Ward Ortmann, Sophie Garnier, Annette T. Lee, Sharon A. Chung, Ricardo C. Ferreira, P.V. Krishna Pant, Dennis G. Ballinger, Roman Kosoy, F. Yesim Demirci, M. Ilyas Kamboh, Amy Kao, Chao Tian, Iva Gunnarsson, Anders Bengtsson, Solbritt Rantapää‐Dahlqvist, Michelle Petri, Susan Manzi, Michael F. Seldin, Lars Rönnblom, Ann Christine Syvänen, Lindsey A. Criswell, Peter K. Gregersen, Timothy W. Behrens - New England Journal of Medicine 2008 cited by 917
- A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
Authors: Vesela Gateva, Johanna K. Sandling, Geoff Hom, Kimberly E. Taylor, Sharon A. Chung, Xin Sun, Ward Ortmann, Roman Kosoy, Ricardo C. Ferreira, Gunnel Nordmark, Iva Gunnarsson, Elisabet Svenungsson, Leonid Padyukov, Gunnar Sturfelt, Andreas Jönsen, Anders Bengtsson, Solbritt Rantapää‐Dahlqvist, Emily C. Baechler, Elizabeth E. Brown, Graciela S. Alarcón, Jeffrey C. Edberg, Rosalind Ramsey‐Goldman, Gerald McGwin, John D. Reveille, Luis M. Vilá, Robert P. Kimberly, Susan Manzi, Michelle Petri, Annette Lee, Peter K. Gregersen, Michael F. Seldin, Lars Rönnblom, Lindsey A. Criswell, Ann-Christine Syvänen, Timothy W. Behrens, Robert Graham - Nature Genetics 2009 cited by 809
- A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
Authors: Robert Graham, Sergey V. Kozyrev, Emily C. Baechler, Mitsu Reddy, Robert M. Plenge, Jason W. Bauer, Ward Ortmann, Thearith Koeuth, Ma Francisca González Escribano, the Argentine and Spanish Collaborative Groups, Bernardo A. Pons‐Estel, Michelle Petri, Mark J. Daly, Peter K. Gregersen, Javier Martı́n, David Altshuler, Timothy W. Behrens, Marta E. Alarcón‐Riquelme - Nature Genetics 2006 cited by 669
- The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression
Authors: Tzu-Ling Hung, Gabriel A. Pratt, Balaji Sundararaman, Michael J. Townsend, Christina Chaivorapol, Tushar Bhangale, Robert Graham, Ward Ortmann, L. A. Criswell, G Yeo, Timothy W. Behrens - Science 2015 cited by 267
- A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death
Authors: Monica K Wetzel-Smith, Julie Hunkapiller, Tushar Bhangale, Karpagam Srinivasan, Janice Maloney, Jasvinder K. Atwal, Manzi Susan, Murat Yaylaoglu, Oded Foreman, Ward Ortmann, Nisha Rathore, David V Hansen, Marc Tessier‐Lavigne, Richard Mayeux, Margaret A. Pericak‐Vance, Jonathan L. Haines, Lindsay A. Farrer, Gerard D. Schellenberg, Alison Goate, Timothy W. Behrens, Carlos Cruchaga, Ryan J. Watts, Robert Graham - Nature Medicine 2014 cited by 155
- An Interferon Signature in the Peripheral Blood of Dermatomyositis Patients is Associated with Disease Activity
Authors: Emily C. Baechler, Jason W. Bauer, Catherine A. Slattery, Ward Ortmann, Karl J. Espe, Jill Novitzke, Steven R. Ytterberg, Peter K. Gregersen, Timothy W. Behrens, Ann M. Reed - Molecular Medicine 2007 cited by 307
- Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease
Authors: Nisha Rathore, Sree R. Ramani, Homer Pantua, Jian Payandeh, Tushar Bhangale, Arthur Wüster, Manav Kapoor, Yonglian Sun, Sharookh B. Kapadia, Lino C. Gonzalez, Ali A. Zarrin, Alison Goate, David V. Hansen, Timothy W. Behrens, Robert Graham - PLoS Genetics 2018 cited by 89
- Three functional variants of IFN regulatory factor 5 ( IRF5 ) define risk and protective haplotypes for human lupus
Authors: Robert Graham, Chieko Kyogoku, Snævar Sigurðsson, Irina Vlasova-St. Louis, Leela Davies, Emily C. Baechler, Robert M. Plenge, Thearith Koeuth, Ward Ortmann, Geoffrey Hom, Jason W. Bauer, Clarence Gillett, Noël P. Burtt, Deborah S. Cunninghame Graham, Robert C. Onofrio, Michelle Petri, Iva Gunnarsson, Elisabet Svenungsson, Lars Rönnblom, Gunnel Nordmark, Peter K. Gregersen, Kathy L. Moser, Patrick M. Gaffney, Lindsey A. Criswell, Timothy J. Vyse, Ann-Christine Syvänen, Paul R. Bohjanen, Mark J. Daly, Timothy W. Behrens, David Altshuler - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 456
- Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus
Authors: Deborah S. Cunninghame Graham, David Morris, Tushar Bhangale, Lindsey A. Criswell, Ann‐Christine Syvänen, Lars Rönnblom, Timothy W. Behrens, Robert Graham, Timothy J. Vyse - PLoS Genetics 2011 cited by 332
- Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE
Authors: William P. Kennedy, Romeo Maciuca, Kristen Wolslegel, Wei Tew, Alexander R. Abbas, Christina Chaivorapol, Alyssa Morimoto, Jacqueline McBride, Paul Brunetta, Bruce C. Richardson, John C. Davis, Timothy W. Behrens, Michael J. Townsend - Lupus Science & Medicine 2015 cited by 157
- Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations
Authors: Chuan Wang, Annika Ahlford, Tiina M. Järvinen, Gunnel Nordmark, Maija‐Leena Eloranta, Iva Gunnarsson, Elisabet Svenungsson, Leonid Padyukov, Gunnar Sturfelt, Andreas Jönsen, Anders Bengtsson, Lennart Truedsson, Catharina Eriksson, Solbritt Rantapää‐Dahlqvist, Christopher Sjöwall, Heikki Julkunen, Lindsey A. Criswell, Robert Graham, Timothy W. Behrens, Juha Kere, Lars Rönnblom, Ann‐Christine Syvänen, Johanna K. Sandling - European Journal of Human Genetics 2012 cited by 123
- Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
Authors: Stacy L. Musone, Kimberly E. Taylor, Timothy T. Lu, Joanne Nititham, Ricardo C. Ferreira, Ward Ortmann, Nataliya Tovbis Shifrin, Michelle Petri, M. Ilyas Kamboh, Susan Manzi, Michael F. Seldin, Peter K. Gregersen, Timothy W. Behrens, Averil Ma, Pui–Yan Kwok, Lindsey A. Criswell - Nature Genetics 2008 cited by 463
- Elevated Serum Levels of Interferon-Regulated Chemokines Are Biomarkers for Active Human Systemic Lupus Erythematosus
Authors: Jason W. Bauer, Emily C. Baechler, Michelle Petri, Franak Batliwalla, Dianna Crawford, Ward Ortmann, Karl J. Espe, Wentian Li, Dhavalkumar D. Patel, Peter K. Gregersen, Timothy W. Behrens - PLoS Medicine 2006 cited by 311
- Interferon‐regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: A validation study
Authors: Jason W. Bauer, Michelle Petri, Franak Batliwalla, Thearith Koeuth, Joseph Wilson, Catherine A. Slattery, Angela Panoskaltsis‐Mortari, Peter K. Gregersen, Timothy W. Behrens, Emily C. Baechler - Arthritis & Rheumatism 2009 cited by 300
- CXCR4 and CXCR7 Have Distinct Functions in Regulating Interneuron Migration
Authors: Yanling Wang, Guangnan Li, Amelia Stanco, Jason E. Long, Dianna Crawford, Gregory B. Potter, Samuel J. Pleasure, Timothy W. Behrens, John L.R. Rubenstein - Neuron 2011 cited by 287
- Lupus Nephritis Susceptibility Loci in Women with Systemic Lupus Erythematosus
Authors: Sharon A. Chung, Elizabeth E. Brown, Adrienne H. Williams, Paula S. Ramos, Céline C. Berthier, Tushar Bhangale, Marta E. Alarcón‐Riquelme, Timothy W. Behrens, Lindsey A. Criswell, Deborah Cunninghame Graham, F. Yesim Demirci, Jeffrey C. Edberg, Patrick M. Gaffney, John B. Harley, Chaim O. Jacob, M. Ilyas Kamboh, Jennifer A. Kelly, Susan Manzi, Kathy L. Moser-Sivils, Laurie Russell, Michelle Petri, Betty P. Tsao, Tim J. Vyse, Raphael Zidovetzki, Matthias Kretzler, Robert P. Kimberly, Barry I. Freedman, Robert Graham, Carl D. Langefeld - Journal of the American Society of Nephrology 2014 cited by 150
- Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q
Authors: Svetlana Pidasheva, Sara Trifari, Anne Phillips, Jason A. Hackney, Yan Ma, Ashley Smith, Sue J. Sohn, Hergen Spits, Randall D. Little, Timothy W. Behrens, Lee Honigberg, Nico Ghilardi, Hilary Clark - PLoS ONE 2011 cited by 120
