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William R. Jacobs

Active 1985–2025

Also published as
William, R. Jacobs
231
Papers
46,290
Citations
129
h-index
224
i10-index

Citations

Citations per year for William R. Jacobs1963: 1 citations1981: 2 citations1983: 2 citations1985: 2 citations1986: 2 citations1987: 6 citations1988: 5 citations1989: 10 citations1990: 13 citations1991: 34 citations1992: 37 citations1993: 96 citations1994: 105 citations1995: 145 citations1996: 201 citations1997: 178 citations1998: 252 citations1999: 262 citations2000: 302 citations2001: 320 citations2002: 344 citations2003: 458 citations2004: 408 citations2005: 448 citations2006: 452 citations2007: 464 citations2008: 396 citations2009: 387 citations2010: 452 citations2011: 382 citations2012: 496 citations2013: 410 citations2014: 549 citations2015: 375 citations2016: 371 citations2017: 367 citations2018: 393 citations2019: 1,227 citations2020: 1,163 citations2021: 1,057 citations2022: 932 citations2023: 589 citations2024: 812 citations2025: 375 citations2026: 12 citations1964–1980: no citations, so these years are not shown1982: no citations, so this year is not shown1984: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,994 citing papers, 30.2% of this breakdownUnited Kingdom: 1,133 citing papers, 8.6% of this breakdownChina: 889 citing papers, 6.7% of this breakdownFrance: 739 citing papers, 5.6% of this breakdownIndia: 715 citing papers, 5.4% of this breakdownGermany: 527 citing papers, 4% of this breakdownCanada: 362 citing papers, 2.7% of this breakdownSouth Africa: 352 citing papers, 2.7% of this breakdownAustralia: 318 citing papers, 2.4% of this breakdownSwitzerland: 313 citing papers, 2.4% of this breakdownNetherlands: 297 citing papers, 2.2% of this breakdownItaly: 270 citing papers, 2% of this breakdown
0%30.2%Other 25.1%

Institutions

Fields

  • Medicine55.6%
  • Biochemistry, Genetics and Molecular Biology21.7%
  • Immunology and Microbiology7.8%
  • Environmental Science5.8%
  • Chemistry2.2%
  • Computer Science1.5%
  • Other5.4%

Topics

  • Tuberculosis Research and Epidemiology15.7%
  • Mycobacterium research and diagnosis10.5%
  • Antibiotic Resistance in Bacteria3.6%
  • Bacteriophages and microbial interactions3.3%
  • Bacterial Genetics and Biotechnology2.5%
  • Biochemical and Molecular Research2%
  • Other62.4%

Coauthors

All papers

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  1. Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice

    Authors: Rafael Prados‐Rosales, Andrés Baena, Luis R. Martinez, José L. Luque-García, Rainer Kalscheuer, Veeraraghavan Usha, Carmen Cámara, Joshua D. Nosanchuk, Gurdyal S. Besra, Bing Chen, Juan Jiménez, Aharona Glatman‐Freedman, William R. Jacobs, Steven A. Porcelli, Arturo Casadevall - Journal of Clinical Investigation 2011 cited by 364

  2. Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application

    Authors: Christopher A. Kerantzas, William R. Jacobs - mBio 2017 cited by 210

  3. High-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse model

    Authors: Rebecca A. Luchtel, Tushar D. Bhagat, Kith Pradhan, William R. Jacobs, Mark Levine, Amit Verma, Niraj Shenoy - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 169

  4. Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug‐tolerant bacteria

    Authors: Anil K. Ojha, Anthony D. Baughn, Dhinakaran Sambandan, Tsungda Hsu, Xavier Trivelli, Yann Guérardel, Anuradha Alahari, Laurent Kremer, William R. Jacobs, Graham F. Hatfull - Molecular Microbiology 2008 cited by 543

  5. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

    Authors: John D. McKinney, Kerstin Höner zu Bentrup, Ernesto J. Muñoz‐Elías, András Miczák, Bing Chen, Wai-Tsing Chan, Dana L. Swenson, James C. Sacchettini, William R. Jacobs, David G. Russell - Nature 2000 cited by 1,368

  6. Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47

    Authors: Neeraj K. Saini, Andrés Baena, Tony W. Ng, Manjunatha M. Venkataswamy, Steven C. Kennedy, Shajo Kunnath-Velayudhan, Leandro J. Carreño, Jiayong Xu, John Chan, Michelle H. Larsen, William R. Jacobs, Steven A. Porcelli - Nature Microbiology 2016 cited by 203

  7. inhA , a Gene Encoding a Target for Isoniazid and Ethionamide in Mycobacterium tuberculosis

    Authors: Asesh Banerjee, Eugenie Dubnau, Annaı̈k Quémard, V. Balasubramanian, Kyung Sun Um, Theresa Wilson, Des Collins, G. de Lisle, William R. Jacobs - Science 1994 cited by 1,389

  8. Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

    Authors: Michael B. Harbut, Catherine Vilchèze, Xiaozhou Luo, Mary E. Hensler, Hui Guo, Baiyuan Yang, Arnab K. Chatterjee, Victor Nizet, William R. Jacobs, Peter G. Schultz, Feng Wang - National Academy of Sciences, Proceedings of the National Academy of Sciences 2015 cited by 332

  9. Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis

    Authors: Eszter Lázár‐Molnár, Bing Chen, Kari A. Sweeney, Emilie J. Wang, Weijun Liu, Juan Lin, Steven A. Porcelli, Steven C. Almo, Stanley G. Nathenson, William R. Jacobs - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 327

  10. New use of BCG for recombinant vaccines

    Authors: C. Kendall Stover, Vidal F. de la Cruz, Thomas R. Fuerst, Jeanne E. Burlein, Lina Benson, Linda Bennett, Geetha P. Bansal, J F Young, Mong‐Hong Lee, Graham F. Hatfull, Scott B. Snapper, Raúl G. Barletta, William R. Jacobs, Barry R. Bloom - Nature 1991 cited by 1,503

  11. Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

    Authors: Scott B. Snapper, Rachel E. Melton, Shuhaimi Mustafa, Tobias Kieser, William R. Jacobs - Molecular Microbiology 1990 cited by 1,264

  12. The primary mechanism of attenuation of bacillus Calmette–Guérin is a loss of secreted lytic function required for invasion of lung interstitial tissue

    Authors: Tsungda Hsu, Suzie Hingley‐Wilson, Bing Chen, Mei Chen, Annie Z. Dai, P Morin, Carolyn B. Marks, Jeevan Padiyar, Celia W. Goulding, Mari Gingery, David Eisenberg, Robert G. Russell, Steven C. Derrick, Frank M. Collins, Sheldon L. Morris, C. Harold King, William R. Jacobs - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 739

  13. Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis

    Authors: Denise A. Rozwarski, Gregory A. Grant, D. H. R. BARTON, William R. Jacobs, James C. Sacchettini - Science 1998 cited by 680

  14. Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction

    Authors: Catherine Vilchèze, Travis Hartman, Brian Weinrick, William R. Jacobs - Nature Communications 2013 cited by 335

  15. Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis : Genes, Mutations, and Causalities

    Authors: Catherine Vilchèze, William R. Jacobs - Microbiology Spectrum 2014 cited by 282

  16. Role for Mycobacterium tuberculosis Membrane Vesicles in Iron Acquisition

    Authors: Rafael Prados‐Rosales, Brian Weinrick, Daniel G. Piqué, William R. Jacobs, Arturo Casadevall, G. Marcela Rodríguez - Journal of Bacteriology 2014 cited by 201

  17. Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis

    Authors: Catherine Vilchèze, Travis Hartman, Brian Weinrick, Paras Jain, Torin R. Weisbrod, Lawrence W. Leung, Joel S. Freundlich, William R. Jacobs - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 189

  18. Mycobacterium tuberculosis Exploits Human Interferon γ to Stimulate Macrophage Extracellular Trap Formation and Necrosis

    Authors: Ka‐Wing Wong, William R. Jacobs - The Journal of Infectious Diseases 2013 cited by 141

  19. TheMycobacterium tuberculosiscapsule: a cell structure with key implications in pathogenesis

    Authors: Rainer Kalscheuer, Ainhoa Palacios, Itxaso Anso, Javier O. Cifuente, Juan Anguíta, William R. Jacobs, Marcelo E. Guerin, Rafael Prados‐Rosales - Biochemical Journal 2019 cited by 131

  20. Origins of Highly Mosaic Mycobacteriophage Genomes

    Authors: Marisa L. Pedulla, Michael E. Ford, Jennifer M. Houtz, Tharun Karthikeyan, Curtis Wadsworth, John A. Lewis, Debbie Jacobs-Sera, Jacob Falbo, Joseph F. Gross, Nicholas R. Pannunzio, William Brucker, Vanaja Kumar, Jayasankar Kandasamy, Lauren Keenan, Svetsoslav Bardarov, Jordan Kriakov, Jeffrey Lawrence, William R. Jacobs, Roger W. Hendrix, Graham F. Hatfull - Cell 2003 cited by 682

  21. Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity

    Authors: Welkin Pope, Charles A. Bowman, Daniel A. Russell, Deborah Jacobs-Sera, David J. Asai, Steven G. Cresawn, William R. Jacobs, Roger W. Hendrix, Jeffrey Lawrence, Graham F. Hatfull, Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science, Mycobacterial Genetics Course - eLife 2015 cited by 326

  22. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

    Authors: Feng Wang, Dhinakaran Sambandan, Rajkumar Halder, Jianing Wang, Sarah M. Batt, Brian Weinrick, Insha Ahmad, Pengyu Yang, Yong Zhang, John Kim, Morad Hassani, Stanislav Huszár, Claudia Jessen‐Trefzer, Zhenkun Ma, Takushi Kaneko, Khisi Mdluli, Scott G. Franzblau, Arnab K. Chatterjee, Kai Johnsson, Katarı́na Mikušová, Gurdyal S. Besra, Klaus Fütterer, Scott H. Robbins, S. Whitney Barnes, John R. Walker, William R. Jacobs, Peter G. Schultz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 226

  23. Specialized Transduction Designed for Precise High-Throughput Unmarked Deletions in Mycobacterium tuberculosis

    Authors: Paras Jain, Tsungda Hsu, Masayoshi Arai, Karolin Biermann, David S. Thaler, Andrew Nguyen, Pablo A. González, JoAnn M. Tufariello, Jordan Kriakov, Bing Chen, Michelle H. Larsen, William R. Jacobs - mBio 2014 cited by 181

  24. Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice

    Authors: Jeffery S. Cox, Bing Chen, Michael McNeil, William R. Jacobs - Nature 1999 cited by 747