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Yoshikatsu Kanai

Active 1992–2025

163
Papers
33,518
Citations
104
h-index
158
i10-index

Citations

Citations per year for Yoshikatsu Kanai1981: 1 citations1985: 1 citations1988: 1 citations1992: 3 citations1993: 27 citations1994: 57 citations1995: 63 citations1996: 81 citations1997: 141 citations1998: 178 citations1999: 203 citations2000: 293 citations2001: 352 citations2002: 439 citations2003: 399 citations2004: 430 citations2005: 314 citations2006: 249 citations2007: 276 citations2008: 420 citations2009: 274 citations2010: 253 citations2011: 260 citations2012: 288 citations2013: 288 citations2014: 334 citations2015: 261 citations2016: 271 citations2017: 259 citations2018: 259 citations2019: 870 citations2020: 1,112 citations2021: 919 citations2022: 721 citations2023: 531 citations2024: 882 citations2025: 344 citations2026: 4 citations1982–1984: no citations, so these years are not shown1986–1987: no citations, so these years are not shown1989–1991: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,488 citing papers, 26.8% of this breakdownChina: 1,054 citing papers, 11.3% of this breakdownJapan: 956 citing papers, 10.3% of this breakdownGermany: 584 citing papers, 6.3% of this breakdownUnited Kingdom: 544 citing papers, 5.9% of this breakdownCanada: 308 citing papers, 3.3% of this breakdownFrance: 283 citing papers, 3% of this breakdownItaly: 262 citing papers, 2.8% of this breakdownSwitzerland: 230 citing papers, 2.5% of this breakdownAustralia: 221 citing papers, 2.4% of this breakdownSpain: 214 citing papers, 2.3% of this breakdownNetherlands: 183 citing papers, 2% of this breakdown
0%26.8%Other 21.1%

Institutions

Fields

  • Medicine41.4%
  • Biochemistry, Genetics and Molecular Biology32.6%
  • Neuroscience17.6%
  • Immunology and Microbiology2.2%
  • Agricultural and Biological Sciences1.8%
  • Environmental Science1.2%
  • Other3.2%

Topics

  • Amino Acid Enzymes and Metabolism7.1%
  • Neuroscience and Neuropharmacology Research5.7%
  • Drug Transport and Resistance Mechanisms4.7%
  • Gout, Hyperuricemia, Uric Acid2.8%
  • Epigenetics and DNA Methylation2.7%
  • Metabolism and Genetic Disorders2.4%
  • Other74.6%

Coauthors

All papers

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  1. Amino acid transporters revisited: New views in health and disease

    Authors: Palanivel Kandasamy, Gergely Gyimesi, Yoshikatsu Kanai, Matthias A. Hediger - Trends in Biochemical Sciences 2018 cited by 480

  2. The SLC3 and SLC7 families of amino acid transporters

    Authors: Dimitrios Fotiadis, Yoshikatsu Kanai, Manuel Palacı́n - Molecular Aspects of Medicine 2013 cited by 689

  3. Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics

    Authors: Yoshikatsu Kanai - Pharmacology & Therapeutics 2021 cited by 304

  4. Molecular identification of a renal urate–anion exchanger that regulates blood urate levels

    Authors: Atsushi Enomoto, Hiroaki Kimura, Arthit Chairoungdua, Yasuhiro Shigeta, Promsuk Jutabha, Seok Ho, Makoto Hosoyamada, Michio Takeda, Takashi Sekine, Takashi Igarashi, Hirotaka Matsuo, Yuichi Kikuchi, Oda T, Kimiyoshi Ichida, Tatsuo Hosoya, Kaoru Shimokata, Toshimitsu Niwa, Yoshikatsu Kanai, Hitoshi Endou - Nature 2002 cited by 1,551

  5. Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder

    Authors: Dora C. Tărlungeanu, Elena Deliu, Christoph Dotter, Majdi Kara, Philipp Christoph Janiesch, Mariafrancesca Scalise, Michele Galluccio, Mateja Rybiczka-Tešulov, Emanuela Morelli, Fatma Müjgan Sönmez, Kaya Bilgüvar, Ryuichi Ohgaki, Yoshikatsu Kanai, Anide Johansen, Seham Esharif, Tawfeg Ben‐Omran, Meral Topçu, Avner Schlessinger, Cesare Indiveri, Kent E. Duncan, Ahmet Okay Çağlayan, Murat Günel, Joseph G. Gleeson, Gaia Novarino - Cell 2016 cited by 370

  6. Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

    Authors: Yoshikatsu Kanai, Hiroko Segawa, Ken‐ichi Miyamoto, Hiroshi Uchino, Eiji Takeda, Hitoshi Endou - Journal of Biological Chemistry 1998 cited by 1,105

  7. Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

    Authors: Jeffrey D. Rothstein, Margaret Dykes‐Hoberg, Carlos A. Pardo, Lynn A. Bristol, Jin Li, Ralph W. Kuncl, Yoshikatsu Kanai, Matthias A. Hediger, Yanfeng Wang, Jerry P Schielke, Devin Welty - Neuron 1996 cited by 2,541

  8. Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines

    Authors: Osamu Yanagida, Yoshikatsu Kanai, Arthit Chairoungdua, Do Kyung Kim, Hiroko Segawa, Tomoko Nii, Seok Ho, Hirotaka Matsuo, Junichi Fukushima, Yoshiki Fukasawa, Yoshiko Tani, Yutaka Taketani, Hiroshi Uchino, Ju Young Kim, Jun Inatomi, Isao Okayasu, Ken‐ichi Miyamoto, Eiji Takeda, Tomoyuki Goya, Hitoshi Endou - Biochimica et Biophysica Acta (BBA) - Biomembranes 2001 cited by 739

  9. Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells

    Authors: Kayo Ikeda, Makoto Kinoshita, Hisako Kayama, Shushi Nagamori, Pornparn Kongpracha, Eiji Umemoto, Ryu Okumura, Takashi Kurakawa, Mari Murakami, Norihisa Mikami, Yasunori Shintani, Satoko Ueno, Ayatoshi Andou, Morihiro Ito, Hideki Tsumura, Koji Yasutomo, Keiichi Ozono, Seiji Takashima, Shimon Sakaguchi, Yoshikatsu Kanai, Kiyoshi Takeda - Cell Reports 2017 cited by 140

  10. Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2

    Authors: Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Ling Wei, Ryuichi Ohgaki, Itsuro Kato, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai - Cancer Science 2015 cited by 188

  11. The SLC1 high-affinity glutamate and neutral amino acid transporter family

    Authors: Yoshikatsu Kanai, Benjamin Clémençon, Alexandre Simonin, Michele Leuenberger, Martin Lochner, Martin Weisstanner, Matthias A. Hediger - Molecular Aspects of Medicine 2013 cited by 327

  12. Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application

    Authors: Gergely Gyimesi, Jonai Pujol‐Giménez, Yoshikatsu Kanai, Matthias A. Hediger - Pflügers Archiv - European Journal of Physiology 2020 cited by 121

  13. CATs and HATs: the SLC7 family of amino acid transporters

    Authors: François Verrey, Ellen I. Closs, Carsten A. Wagner, Manuel Palacı́n, Hitoshi Endou, Yoshikatsu Kanai - Pflügers Archiv - European Journal of Physiology 2004 cited by 710

  14. l‐Type amino acid transporter 1 inhibitors inhibit tumor cell growth

    Authors: Koji Oda, Noriko Hosoda, Hiroshi Endô, Kunio SAITO, Kenji Tsujihara, Michio Yamamura, Takeshi Sakata, Naohiko Anzai, Michael F. Wempe, Yoshikatsu Kanai, Hitoshi Endou - Cancer Science 2009 cited by 270

  15. Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

    Authors: Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Takahiro Nakamura, Akiyoshi Nakayama, Yuki Ikebuchi, Kousei Ito, Yasuyoshi Kusanagi, Toshinori Chiba, Shin Tadokoro, Yuzo Takada, Yuji Oikawa, Hiroki Inoue, Koji Suzuki, Rieko Okada, Junichiro Nishiyama, Hideharu Domoto, Satoru Watanabe, Masanori Fujita, Yuji Morimoto, Mariko Naito, Kazuko Nishio, Asahi Hishida, Kenji Wakai, Yatami Asai, Kazuki Niwa, Keiko Kamakura, Shigeaki Nonoyama, Yutaka Sakurai, Tatsuo Hosoya, Yoshikatsu Kanai, Hiroshi Suzuki, Nobuyuki Hamajima, Nariyoshi Shinomiya - Science Translational Medicine 2009 cited by 435

  16. Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

    Authors: Yongchan Lee, Pattama Wiriyasermkul, Chunhuan Jin, Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazumasa Oda, Ryuichiro Ishitani, Takeshi Yokoyama, Takanori Nakane, Mikako Shirouzu, Hitoshi Endou, Shushi Nagamori, Yoshikatsu Kanai, Osamu Nureki - Nature Structural & Molecular Biology 2019 cited by 179

  17. Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity

    Authors: Hiroko Segawa, Yoshiki Fukasawa, Ken‐ichi Miyamoto, Eiji Takeda, Hitoshi Endou, Yoshikatsu Kanai - Journal of Biological Chemistry 1999 cited by 500

  18. Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia

    Authors: Hirotaka Matsuo, Toshinori Chiba, Shushi Nagamori, Akiyoshi Nakayama, Hideharu Domoto, Kanokporn Phetdee, Pattama Wiriyasermkul, Yuichi Kikuchi, Oda T, Junichiro Nishiyama, Takahiro Nakamura, Yuji Morimoto, Keiko Kamakura, Yutaka Sakurai, Shigeaki Nonoyama, Yoshikatsu Kanai, Nariyoshi Shinomiya - The American Journal of Human Genetics 2008 cited by 388

  19. CYP450s-Activity Relations of Celastrol to Interact with Triptolide Reveal the Reasons of Hepatotoxicity of Tripterygium wilfordii

    Authors: Chunhuan Jin, Zijun Wu, Lili Wang, Yoshikatsu Kanai, Xin He - Molecules 2019 cited by 75

  20. NPT1/SLC17A1 Is a Renal Urate Exporter in Humans and Its Common Gain‐of‐Function Variant Decreases the Risk of Renal Underexcretion Gout

    Authors: Toshinori Chiba, Hirotaka Matsuo, Yusuke Kawamura, Shushi Nagamori, Takashi Nishiyama, Wei Ling, Akiyoshi Nakayama, Takahiro Nakamura, Masayuki Sakiyama, Tappei Takada, Yutaka Taketani, Shino Suma, Mariko Naito, Oda T, Hiroo Kumagai, Yoshinori Moriyama, Kimiyoshi Ichida, Toru Shimizu, Yoshikatsu Kanai, Nariyoshi Shinomiya - Arthritis & Rheumatology 2014 cited by 91

  21. Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation

    Authors: Lili Quan, Ryuichi Ohgaki, Saori Hara, Suguru Okuda, Ling Wei, Hiroki Okanishi, Shushi Nagamori, Hitoshi Endou, Yoshikatsu Kanai - Journal of Experimental & Clinical Cancer Research 2020 cited by 73

  22. Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2

    Authors: T. Kato, Tsukasa Kusakizako, Chunhuan Jin, Xinyu Zhou, Ryuichi Ohgaki, Lili Quan, Minhui Xu, Suguru Okuda, Kan Kobayashi, Keitaro Yamashita, Tomohiro Nishizawa, Yoshikatsu Kanai, Osamu Nureki - Nature Communications 2022 cited by 47

  23. Transport of Amino Acid-Related Compounds Mediated by L-Type Amino Acid Transporter 1 (LAT1): Insights Into the Mechanisms of Substrate Recognition

    Authors: Hiroshi Uchino, Yoshikatsu Kanai, Do Kyung Kim, Michael F. Wempe, Arthit Chairoungdua, Emiko Morimoto, M. W. Anders, Hitoshi Endou - Molecular Pharmacology 2002 cited by 406

  24. The 4F2hc/LAT1 complex transports l-DOPA across the blood–brain barrier

    Authors: Takashi Kageyama, Masaru Nakamura, Akinori Matsuo, Yasuomi Yamasaki, Yoshinobu Takakura, Mitsuru Hashida, Yoshikatsu Kanai, Mikihiko Naito, Takashi Tsuruo, Nagahiro Minato, Shun Shimohama - Brain Research 2000 cited by 293