Daily blueberry consumption for 12 weeks improves endothelial function in postmenopausal women with above-normal blood pressure through reductions in oxidative stress: a randomized controlled trial

Authors: Emily K. Woolf, Janée D. Terwoord, Nicole S. Litwin, Allegra R. Vazquez, Sylvia Lee, Nancy Ghanem, Kiri Michell, Brayden T. Smith, Lauren E. Grabos, Nathaniel B. Ketelhut, Nate P. Bachman, M. Smith, Mélanie Le Sayec, Sangeeta Rao, Christopher L. Gentile, Tiffany L. Weir, Ana Rodriguez‐Mateos, Douglas R. Seals, Frank A. Dinenno, Sarah A. Johnson - Food & Function 2023 cited by 40

< 0.05). Increases in several plasma flavonoid and microbial metabolites were also noted. No major differences were found for blood pressure, arterial stiffness, blood biomarkers, or endothelial cell protein expression following blueberry consumption. These findings suggest daily consumption of freeze-dried blueberry powder for 12 weeks improves endothelial function through reduced oxidative stress in postmenopausal women with above-normal blood pressure. The clinical trial registry number is NCT03370991 (https://clinicaltrials.gov).