Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD

Authors: Ruxandra Dafinca, Paola Barbagallo, Lucy Farrimond, Ana Candalija, Jakub Scaber, Nidaa A. Ababneh, Chaitra Sathyaprakash, Jane Vowles, Sally A. Cowley, Kevin Talbot - Stem Cell Reports 2020 cited by 131

uptake contributes to glutamate excitotoxicity and is a shared feature of MNs with C9ORF72 or TARDBP mutations.