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Alan Ashworth

1979–2026 年に発表

284
論文数
83,441
被引用数
147
h 指数
280
i10 指数

被引用数

Alan Ashworth の年別被引用数1943 年: 被引用 1 件1948 年: 被引用 1 件1982 年: 被引用 1 件1985 年: 被引用 1 件1988 年: 被引用 1 件1989 年: 被引用 5 件1990 年: 被引用 4 件1991 年: 被引用 10 件1992 年: 被引用 25 件1993 年: 被引用 51 件1994 年: 被引用 96 件1995 年: 被引用 122 件1996 年: 被引用 209 件1997 年: 被引用 312 件1998 年: 被引用 373 件1999 年: 被引用 342 件2000 年: 被引用 286 件2001 年: 被引用 308 件2002 年: 被引用 257 件2003 年: 被引用 241 件2004 年: 被引用 324 件2005 年: 被引用 337 件2006 年: 被引用 433 件2007 年: 被引用 494 件2008 年: 被引用 603 件2009 年: 被引用 697 件2010 年: 被引用 1,064 件2011 年: 被引用 1,036 件2012 年: 被引用 979 件2013 年: 被引用 937 件2014 年: 被引用 971 件2015 年: 被引用 985 件2016 年: 被引用 1,000 件2017 年: 被引用 1,042 件2018 年: 被引用 1,009 件2019 年: 被引用 2,820 件2020 年: 被引用 3,323 件2021 年: 被引用 2,975 件2022 年: 被引用 2,327 件2023 年: 被引用 1,618 件2024 年: 被引用 2,320 件2025 年: 被引用 1,145 件2026 年: 被引用 40 件1944〜1947 年は被引用が無いため表示していません1949〜1981 年は被引用が無いため表示していません1983〜1984 年は被引用が無いため表示していません1986〜1987 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 10,024 件、この内訳の 28.7%イギリス: 引用元論文 3,595 件、この内訳の 10.3%中国: 引用元論文 3,141 件、この内訳の 9%ドイツ: 引用元論文 1,650 件、この内訳の 4.7%カナダ: 引用元論文 1,414 件、この内訳の 4%フランス: 引用元論文 1,351 件、この内訳の 3.9%イタリア: 引用元論文 1,297 件、この内訳の 3.7%オーストラリア: 引用元論文 1,044 件、この内訳の 3%オランダ: 引用元論文 990 件、この内訳の 2.8%日本: 引用元論文 941 件、この内訳の 2.7%スペイン: 引用元論文 913 件、この内訳の 2.6%スイス: 引用元論文 632 件、この内訳の 1.8%
0%28.7%その他 22.8%

機関

分野

  • Biochemistry, Genetics and Molecular Biology52.1%
  • Medicine40.3%
  • Immunology and Microbiology2.8%
  • Computer Science1.1%
  • Neuroscience1.1%
  • Engineering0.5%
  • その他2.1%

トピック

  • PARP inhibition in cancer therapy5.8%
  • DNA Repair Mechanisms5.3%
  • Cancer Genomics and Diagnostics3%
  • BRCA gene mutations in cancer2.9%
  • CRISPR and Genetic Engineering2.5%
  • Epigenetics and DNA Methylation2.1%
  • その他78.4%

共著者

全論文

検索で開く
  1. PARP inhibitors: Synthetic lethality in the clinic

    著者: Christopher J. Lord, Alan Ashworth - Science 2017 被引用: 2,937

  2. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

    著者: Hannah Farmer, Nuala McCabe, Christopher J. Lord, Andrew Tutt, Damian A. Johnson, Tobias B. Richardson, Manuela Santarosa, Krystyna J. Dillon, Ian Hickson, Charlotte Knights, Niall M.B. Martin, Stephen P. Jackson, Graeme C.M. Smith, Alan Ashworth - Nature 2005 被引用: 6,735

  3. Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

    著者: Julia A. Belk, Winnie Yao, Nghi Ly, Katherine A. Freitas, Yanting Chen, Quanming Shi, Alfredo M. Valencia, Eric Shifrut, Nupura Kale, Kathryn E. Yost, Connor V. Duffy, Bence Dániel, Madeline A. Hwee, Zhuang Miao, Alan Ashworth, Crystal L. Mackall, Alexander Marson, Julia Carnevale, Santosha A. Vardhana, Ansuman T. Satpathy - Cancer Cell 2022 被引用: 350

  4. Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers

    著者: Peter C.C. Fong, David S. Boss, Timothy A. Yap, Andrew Tutt, Peijun Wu, Marja Mergui‐Roelvink, Peter G. Mortimer, Helen Swaisland, Alan Lau, Mark J. O’Connor, Alan Ashworth, James Carmichael, Stan B. Kaye, Jan H.M. Schellens, Johann S. de Bono - New England Journal of Medicine 2009 被引用: 3,632

  5. DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

    著者: Joaquı́n Mateo, Suzanne Carreira, Shahneen Sandhu, Susana Miranda, Helen Mossop, Raquel Pérez-López, Daniel Nava Rodrigues, Dan R. Robinson, Aurelius Omlin, Nina Tunariu, Gunther Boysen, Núria Porta, Penny Flohr, Alexa Gillman, Ines Figueiredo, Claire Paulding, George Seed, Suneil Jain, Christy Ralph, Andrew Protheroe, Syed A. Hussain, Robert J. Jones, Tony Elliott, Ursula McGovern, Diletta Bianchini, Jane Goodall, Zafeiris Zafeiriou, Chris T. Williamson, Roberta Ferraldeschi, Ruth Riisnaes, Bernardette Ebbs, Gemma Fowler, Desamparados Roda, Wei Yuan, Yi‐Mi Wu, Xuhong Cao, Rachel Brough, Helen N. Pemberton, Roger A’Hern, Amanda Swain, Lakshmi P. Kunju, Rosalind A. Eeles, Gerhardt Attard, Christopher J. Lord, Alan Ashworth, Mark A. Rubin, Karen E. Knudsen, Felix Y. Feng, Arul M. Chinnaiyan, Emma Hall, Johann S. de Bono - New England Journal of Medicine 2015 被引用: 2,187

  6. Reprogramming human T cell function and specificity with non-viral genome targeting

    著者: Theodore L. Roth, Cristina Puig-Saus, Ruby Yu, Eric Shifrut, Julia Carnevale, P. Jonathan Li, Joseph Hiatt, Justin D. Saco, Paige Krystofinski, Han Li, Victoria Tobin, David N. Nguyen, Michael R. Lee, Amy Putnam, Andrea L. Ferris, Jeff W. Chen, Jean-Nicolas Schickel, Laurence Pellerin, David Carmody, Gorka Alkorta‐Aranburu, Daniela del Gaudio, Hiroyuki Matsumoto, Montse Morell, Ying Mao, Min Cho, Rolen M. Quadros, Channabasavaiah B. Gurumurthy, Baz Smith, Michael Haugwitz, Stephen H. Hughes, Jonathan S. Weissman, Kathrin Schumann, Jonathan H. Esensten, Andrew P. May, Alan Ashworth, Gary M. Kupfer, Siri Atma W. Greeley, Rosa Bacchetta, Eric Meffre, Maria Grazia Roncarolo, Neil Romberg, Kevan C. Herold, Antoni Ribas, Manuel D. Leonetti, Alexander Marson - Nature 2018 被引用: 871

  7. Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

    著者: David A. Quigley, Ha X. Dang, Shuang G. Zhao, Paul Lloyd, Rahul Aggarwal, Joshi J. Alumkal, Adam Foye, Vishal Kothari, Marc D. Perry, Adina Bailey, Denise Playdle, Travis J. Barnard, Li Zhang, Jin Zhang, Jack Youngren, Marcin Cieślik, Abhijit Parolia, Tomasz M. Beer, George Thomas, Kim N., Martin Gleave, Nathan A. Lack, Amina Zoubeidi, Robert E. Reiter, Matthew B. Rettig, Owen N. Witte, Charles J. Ryan, Lawrence Fong, Won Bae Kim, Terence W. Friedlander, Jonathan Chou, Haolong Li, Rajdeep Das, Hui Li, Ruhollah Moussavi-Baygi, Hani Goodarzi, Luke A. Gilbert, Primo N. Lara, Christopher P. Evans, Theodore C. Goldstein, Joshua M. Stuart, Scott A. Tomlins, Daniel E. Spratt, R. Keira Cheetham, Donavan T. Cheng, Kyle Kai‐How Farh, Julian Gehring, Jörg Hakenberg, Arnold Liao, Philip G. Febbo, John Shon, Brad Sickler, Serafim Batzoglou, Karen E. Knudsen, Housheng Hansen He, Jiaoti Huang, Alexander W. Wyatt, Scott M. Dehm, Alan Ashworth, Arul M. Chinnaiyan, Christopher A. Maher, Eric J. Small, Felix Y. Feng - Cell 2018 被引用: 759

  8. Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

    著者: Eric Shifrut, Julia Carnevale, Victoria Tobin, Theodore L. Roth, Jonathan M. Woo, Christina Bui, P. Jonathan Li, Morgan E. Diolaiti, Alan Ashworth, Alexander Marson - Cell 2018 被引用: 581

  9. BRCAness revisited

    著者: Christopher J. Lord, Alan Ashworth - Nature reviews. Cancer 2016 被引用: 1,250

  10. The DNA damage response and cancer therapy

    著者: Christopher J. Lord, Alan Ashworth - Nature 2012 被引用: 1,829

  11. Synthetic lethality as an engine for cancer drug target discovery

    著者: Alan Huang, Levi A. Garraway, Alan Ashworth, Barbara L. Weber - Nature Reviews Drug Discovery 2019 被引用: 469

  12. ADP‐ribosyltransferases, an update on function and nomenclature

    著者: Bernhard Lüscher, Ivan Ahel, Matthias Altmeyer, Alan Ashworth, Péter Bai, Paul Chang, Michael S. Cohen, Daniela Corda, Françoise Dantzer, Matthew D. Daugherty, Ted M. Dawson, Valina L. Dawson, Sebastian Deindl, Anthony R. Fehr, Karla L. H. Feijs, Dmitri V. Filippov, Jean‐Philippe Gagné, Giovanna Grimaldi, Sebastian Guettler, Nícolas C. Hoch, Michael O. Hottiger, Patricia Korn, W. Lee Kraus, Andreas G. Ladurner, L. Lehtiö, Anthony K. L. Leung, Christopher J. Lord, Aswin Mangerich, Ivan Matić, Jason Matthews, George‐Lucian Moldovan, Joel Moss, Gioacchino Natoli, Michael L. Nielsen, Mario Niepel, F. Nolte, John M. Pascal, Bryce M. Paschal, Krzysztof Pawłowski, Guy G. Poirier, Susan Smith, Gyula Timinszky, Zhao‐Qi Wang, José Yélamos, Xiaochun Yu, Roko Žaja, Mathias Ziegler - FEBS Journal 2021 被引用: 327

  13. RASA2 ablation in T cells boosts antigen sensitivity and long-term function

    著者: Julia Carnevale, Eric Shifrut, Nupura Kale, William A. Nyberg, Franziska Blaeschke, Yan Yi Chen, Zhongmei Li, Sagar P. Bapat, Morgan E. Diolaiti, Patrick C. O’Leary, Shane Vedova, Julia A. Belk, Bence Dániel, Theodore L. Roth, Stefanie Bachl, Alejandro Allo Anido, Brooke Prinzing, Jorge Ibañez-Vega, Shannon Lange, Dalia Haydar, Marie Luetke-Eversloh, Maëlys Born-Bony, Bindu Hegde, Scott C. Kogan, Tobias Feuchtinger, Hideho Okada, Ansuman T. Satpathy, Kevin Shannon, Stephen Gottschalk, Justin Eyquem, Giedre Krenciute, Alan Ashworth, Alexander Marson - Nature 2022 被引用: 223

  14. Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

    著者: Stephen J. Pettitt, Dragomir B. Krastev, Inger Brandsma, Amy Dréan, Feifei Song, Radoslav Aleksandrov, Maria I. Harrell, Malini Menon, Rachel Brough, James Campbell, Jessica Frankum, Michael Ranes, Helen N. Pemberton, Rumana Rafiq, Kerry Fenwick, Amanda Swain, Sebastian Guettler, Jung-Min Lee, Elizabeth M. Swisher, Stoyno Stoynov, Kosuke Yusa, Alan Ashworth, Christopher J. Lord - Nature Communications 2018 被引用: 447

  15. The DNA methylation landscape of advanced prostate cancer

    著者: Shuang G. Zhao, William S. Chen, Haolong Li, Adam Foye, Meng Zhang, Martin Sjöström, Rahul Aggarwal, Denise Playdle, Arnold Liao, Joshi J. Alumkal, Rajdeep Das, Jonathan Chou, Junjie T. Hua, Travis J. Barnard, Adina Bailey, Eric D. Chow, Marc D. Perry, Ha X. Dang, Rendong Yang, Ruhollah Moussavi-Baygi, Li Zhang, Mohammed Alshalalfa, S. Laura Chang, Kathleen E. Houlahan, Yu-Jia Shiah, Tomasz M. Beer, George Thomas, Kim N., Martin Gleave, Amina Zoubeidi, Robert E. Reiter, Matthew B. Rettig, Owen N. Witte, M. Yvonne Kim, Lawrence Fong, Daniel E. Spratt, Todd M. Morgan, Rohit Bose, Franklin W. Huang, Hui Li, Lisa N. Chesner, Tanushree Shenoy, Hani Goodarzi, Irfan A. Asangani, Shahneen Sandhu, Joshua M. Lang, Nupam P. Mahajan, Primo N. Lara, Christopher P. Evans, Phillip G. Febbo, Serafim Batzoglou, Karen E. Knudsen, Housheng Hansen He, Jiaoti Huang, Wilbert Zwart, J Costello, Jianhua Luo, Scott A. Tomlins, Alexander W. Wyatt, Scott M. Dehm, Alan Ashworth, Luke A. Gilbert, Paul C. Boutros, Kyle Kai‐How Farh, Arul M. Chinnaiyan, Christopher A. Maher, Eric J. Small, David A. Quigley, Felix Y. Feng - Nature Genetics 2020 被引用: 353

  16. Transcription-Associated Cyclin-Dependent Kinases as Targets and Biomarkers for Cancer Therapy

    著者: Jonathan Chou, David A. Quigley, Troy M. Robinson, Felix Y. Feng, Alan Ashworth - Cancer Discovery 2020 被引用: 293

  17. PARP inhibition enhances tumor cell–intrinsic immunity in ERCC1-deficient non–small cell lung cancer

    著者: Roman M. Chabanon, Gareth Muirhead, Dragomir B. Krastev, Julien Adam, Daphné Morel, Marlène Garrido, Andrew Lamb, Clémence Henon, Nicolas Dorvault, Mathieu Rouanne, Rebecca Marlow, Ilirjana Bajrami, Marta Llorca Cardeñosa, Asha Konde, Benjamin Besse, Alan Ashworth, Stephen J. Pettitt, Syed Haider, Aurélien Marabelle, Andrew Tutt, Jean‐Charles Soria, Christopher J. Lord, Sophie Postel‐Vinay - Journal of Clinical Investigation 2018 被引用: 324

  18. ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

    著者: Chris T. Williamson, Rowan Miller, Helen N. Pemberton, Samuel E. Jones, James Campbell, Asha Konde, Nicholas Badham, Rumana Rafiq, Rachel Brough, Aditi Gulati, Colm J. Ryan, Jeffrey C. Francis, Peter B. Vermulen, Andrew R. Reynolds, Philip M. Reaper, John R. Pollard, Alan Ashworth, Christopher J. Lord - Nature Communications 2016 被引用: 387

  19. Resistance to therapy caused by intragenic deletion in BRCA2

    著者: Stacey L. Edwards, Rachel Brough, Christopher J. Lord, Rachael Natrajan, Radost Vatcheva, Douglas A. Levine, Jeff Boyd, Jorge S. Reis‐Filho, Alan Ashworth - Nature 2008 被引用: 1,012

  20. Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA

    著者: Gulfem D. Guler, Yuhong Ning, Chin‐Jen Ku, Tierney Phillips, Erin McCarthy, Christopher K. Ellison, Anna Bergamaschi, François Collin, Paul Lloyd, Aaron Scott, Michael Antoine, Wendy Wang, Kim Chau, Alan Ashworth, Stephen R. Quake, Samuel Levy - Nature Communications 2020 被引用: 186

  21. Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

    著者: M. Schuller, G.J. Correy, Stefan Gahbauer, D. Fearon, Taiasean Wu, Roberto Efraín Díaz, I.D. Young, Luan Carvalho Martins, Dominique H. Smith, Ursula Schulze‐Gahmen, Tristan W. Owens, Ishan Deshpande, Gregory E. Merz, Aye C. Thwin, J.T. Biel, Jessica K. Peters, Michelle Moritz, Nadia Herrera, Huong T. Kratochvil, A. Aimon, James M. Bennett, J. Brandão-Neto, Aina E. Cohen, Alexandre Dias, A. Douangamath, Louise Dunnett, Oleg Fedorov, Matteo P. Ferla, Martin R. Fuchs, T.J. Gorrie-Stone, James M. Holton, Michael G. Johnson, T. Krojer, G. Meigs, A.J. Powell, J.G.M. Rack, V.L. Rangel, Silvia Russi, R. Skyner, Clyde A. Smith, Alexei S. Soares, Jennifer L. Wierman, Kang Zhu, Peter O’Brien, Natalia Jura, Alan Ashworth, John J. Irwin, Michael C. Thompson, Jason E. Gestwicki, F. von Delft, Brian K. Shoichet, James S. Fraser, Ivan Ahel - Science Advances 2021 被引用: 208

  22. Identification of the breast cancer susceptibility gene BRCA2

    著者: Richard Wooster, Graham R. Bignell, Jonathan Lancaster, Sally Swift, Sheila Seal, Jonathan Mangion, Nadine Collins, Simon G. Gregory, Curtis Gumbs, Gos Micklem, Rita Barfoot, Rifat Hamoudi, Sandeep Patel, Catherine Rices, Patrick J. Biggs, Yasmin Hashim, Amanda Smith, Frances Connor, Aðalgeir Arason, Jūlı́us Guðmundsson, D. Ficenec, David P. Kelsell, Deborah Ford, Patricia N. Tonin, D. Timothy Bishop, Nigel K. Spurr, Bruce A.J. Ponder, Rosalind A. Eeles, Julian Peto, Peter Devilee, Cees J. Cornelisse, Henry T. Lynch, Steven A. Narod, Gilbert Lenoir, V Egilsson, Rosa Bjork Barkadottir, Douglas F. Easton, David Bentley, P. Andrew Futreal, Alan Ashworth, Michael R. Stratton - Nature 1995 被引用: 3,663

  23. Synthetic lethal therapies for cancer: what’s next after PARP inhibitors?

    著者: Alan Ashworth, Christopher J. Lord - Nature Reviews Clinical Oncology 2018 被引用: 421

  24. Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

    著者: Nuala McCabe, Nicholas C. Turner, Christopher J. Lord, Katarzyna Kluzek, Aneta Białkowska, Sally Swift, Sabrina Giavara, Mark J. O’Connor, Andrew Tutt, Małgorzata Z. Zdzienicka, Graeme C.M. Smith, Alan Ashworth - Cancer Research 2006 被引用: 1,305