Arthur Christopoulos
1997–2025 年に発表
- 168
- 論文数
- 34,240
- 被引用数
- 95
- h 指数
- 163
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology45%
- Medicine28.6%
- Neuroscience12.7%
- Computer Science4%
- Immunology and Microbiology1.8%
- Psychology1.6%
- その他6.3%
トピック
- Receptor Mechanisms and Signaling13.6%
- Neuropeptides and Animal Physiology7%
- Computational Drug Discovery Methods3.6%
- Neuroscience and Neuropharmacology Research3.2%
- Monoclonal and Polyclonal Antibodies Research2.1%
- Neurotransmitter Receptor Influence on Behavior2%
- その他68.5%
共著者
- Patrick M. Sexton104
- Denise Wootten36
- Céline Valant30
- Lauren T. May18
- Peter J. Scammells18
- David M. Thal17
- Katie Leach17
- Radostin Danev17
- Yi-Lynn Liang17
- Laurence J. Miller16
- Sebastian G. B. Furness16
- Alisa Glukhova15
- Karen J. Gregory15
- J. Robert Lane14
- Andrew B. Tobin11
- Cassandra Koole11
- Matthew J. Belousoff11
- Christian C. Felder10
- Meritxell Canals10
- Christopher J. Draper-Joyce9
- Christopher J. Langmead9
- Debbie L. Hay9
- Anthony P. Davenport8
- Ben Capuano8
全論文
- The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
著者: S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Jamie A. Davies, Maria P. Abbracchio, George Abraham, Alexander I. Agoulnik, Wayne Alexander, Khaled Alhosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross A. D. Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kenneth E. Bernstein, Bernhard Bettler, N.J.M. Birdsall, Victoria A. Blaho, François Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Calò, Justo P. Castaño, Kevin Catt, Stefania Ceruti, Paul L. Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Cláes Dahlgren, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung M. Fong, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Craig Gerard, Marvin C. Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Ákos Heinemann, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniël Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S. Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Paweł Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li ほか 66 名 - British Journal of Pharmacology 2023 被引用: 388
- Mechanisms of signalling and biased agonism in G protein-coupled receptors
著者: Denise Wootten, Arthur Christopoulos, Maria Martí-Solano, M. Madan Babu, Patrick M. Sexton - Nature Reviews Molecular Cell Biology 2018 被引用: 737
- Activation and allosteric modulation of a muscarinic acetylcholine receptor
著者: Andrew C. Kruse, Aaron M. Ring, Aashish Manglik, Jianxin Hu, Kelly Hu, Katrin Eitel, Harald Hübner, Els Pardon, Céline Valant, Patrick M. Sexton, Arthur Christopoulos, Christian C. Felder, Peter Gmeiner, Jan Steyaert, William I. Weis, K. Christopher García, Jürgen Wess, Brian K. Kobilka - Nature 2013 被引用: 920
- Signalling bias in new drug discovery: detection, quantification and therapeutic impact
著者: Terry Kenakin, Arthur Christopoulos - Nature Reviews Drug Discovery 2012 被引用: 725
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
著者: S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A. Davies, Maria P. Abbracchio, Wayne Alexander, Khaled Alhosaini, Magnus Bäck, Nicholas M. Barnes, Ross A. D. Bathgate, Jean‐Martin Beaulieu, Kenneth E. Bernstein, Bernhard Bettler, N.J.M. Birdsall, Victoria A. Blaho, François Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Calò, Justo P. Castaño, Kevin Catt, Stefania Ceruti, Paul L. Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Zsolt Csaba, Cláes Dahlgren, Gordon Dent, Khuraijam Dhanachandra Singh, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung M. Fong, Marta Fumagalli, Raul R. Gainetdinov, Marc de Gasparo, Craig Gerard, Marvin C. Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Ákos Heinemann, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniël Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S. Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Paweł Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li, Tom A. Williams, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Jean Mazella, Craig A. McArdle ほか 55 名 - British Journal of Pharmacology 2021 被引用: 488
- Emerging paradigms in GPCR allostery: implications for drug discovery
著者: Denise Wootten, Arthur Christopoulos, Patrick M. Sexton - Nature Reviews Drug Discovery 2013 被引用: 493
- Structural insights into G-protein-coupled receptor allostery
著者: David M. Thal, Alisa Glukhova, Patrick M. Sexton, Arthur Christopoulos - Nature 2018 被引用: 339
- Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia
著者: Christopher J. Draper-Joyce, Rebecca F. Bhola, Jinan Wang, Apurba Bhattarai, Thi Nguyen, India Cowie-Kent, Kelly O’Sullivan, Ling Yeong Chia, Hariprasad Venugopal, Céline Valant, David M. Thal, Denise Wootten, Nicolas Panel, Jens Carlsson, MacDonald J. Christie, Paul J. White, Peter J. Scammells, Lauren T. May, Patrick M. Sexton, Radostin Danev, Yinglong Miao, Alisa Glukhova, Wendy L. Imlach, Arthur Christopoulos - Nature 2021 被引用: 158
- The role of kinetic context in apparent biased agonism at GPCRs
著者: Carmen Klein Herenbrink, David A. Sykes, Prashant Donthamsetti, Meritxell Canals, Thomas Coudrat, Jeremy Shonberg, Peter J. Scammells, Ben Capuano, Patrick M. Sexton, Steven J. Charlton, Jonathan A. Javitch, Arthur Christopoulos, J. Robert Lane - Nature Communications 2016 被引用: 337
- Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
著者: P. Jeffrey Conn, Arthur Christopoulos, Craig W. Lindsley - Nature Reviews Drug Discovery 2008 被引用: 1,042
- Muscarinic acetylcholine receptors: novel opportunities for drug development
著者: Andrew C. Kruse, Brian K. Kobilka, Dinesh Gautam, Patrick M. Sexton, Arthur Christopoulos, Jürgen Wess - Nature Reviews Drug Discovery 2014 被引用: 439
- Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation
著者: Jean‐Pierre Changeux, Arthur Christopoulos - Cell 2016 被引用: 350
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors
著者: S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A. Davies, CGTP Collaborators - British Journal of Pharmacology 2019 被引用: 712
- Activation of the GLP-1 receptor by a non-peptidic agonist
著者: Peishen Zhao, Yi-Lynn Liang, Matthew J. Belousoff, Giuseppe Deganutti, Madeleine M. Fletcher, Francis S. Willard, Michael G. Bell, Michael E. Christe, Kyle W. Sloop, Asuka Inoue, Tin T. Truong, Lachlan Clydesdale, Sebastian G. B. Furness, Arthur Christopoulos, Ming-Wei Wang, Laurence J. Miller, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten - Nature 2020 被引用: 168
- Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination
著者: Yi-Lynn Liang, Peishen Zhao, Christopher J. Draper-Joyce, Jo‐Anne Baltos, Alisa Glukhova, Tin T. Truong, Lauren T. May, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton, Sebastian G. B. Furness - ACS Pharmacology & Translational Science 2018 被引用: 156
- Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex
著者: Yi-Lynn Liang, Maryam Khoshouei, Alisa Glukhova, Sebastian G. B. Furness, Peishen Zhao, Lachlan Clydesdale, Cassandra Koole, Tin T. Truong, David M. Thal, Saifei Lei, Mazdak Radjainia, Radostin Danev, Wolfgang Baumeister, Ming-Wei Wang, Laurence J. Miller, Arthur Christopoulos, Patrick M. Sexton, Denise Wootten - Nature 2018 被引用: 332
- Functional Selectivity and Classical Concepts of Quantitative Pharmacology
著者: Jonathan D. Urban, William P. Clarke, Mark von Zastrow, David E. Nichols, Brian K. Kobilka, Harel Weinstein, Jonathan A. Javitch, Bryan L. Roth, Arthur Christopoulos, Patrick M. Sexton, Keith J. Miller, Michael Spedding, Richard B. Mailman - Journal of Pharmacology and Experimental Therapeutics 2006 被引用: 1,109
- A Simple Method for Quantifying Functional Selectivity and Agonist Bias
著者: Terry Kenakin, Christian Watson, Vanessa Muniz‐Medina, Arthur Christopoulos, Steven Novick - ACS Chemical Neuroscience 2011 被引用: 486
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets
著者: S P H Alexander, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, O. Buneman, John A. Cidlowski, Arthur Christopoulos, Anthony P. Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, Jamie A. Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi Pal Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill A. Martemyanov, Luke D. Mascarenhas, Harrison J. McNabb, Carolina Montañez‐Miranda, Osita W. Ogujiofor, H. T. Phan, David L. Roman, Vincent Shaw, Benita Sjögren, Christopher G. Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie P. Sutton, Menbere Wendimu, Thomas M. Wilkie, Keqiang Xie, Qian Zhang, Yalda Zolghadri - British Journal of Pharmacology 2021 被引用: 275
- Phase-plate cryo-EM structure of a class B GPCR–G-protein complex
著者: Yi-Lynn Liang, Maryam Khoshouei, Mazdak Radjainia, Yan Zhang, Alisa Glukhova, Jeffrey Tarrasch, David M. Thal, Sebastian G. B. Furness, George Christopoulos, Thomas Coudrat, Radostin Danev, Wolfgang Baumeister, Laurence J. Miller, Arthur Christopoulos, Brian K. Kobilka, Denise Wootten, Georgios Skiniotis, Patrick M. Sexton - Nature 2017 被引用: 480
- Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations
著者: Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos, Patrick M. Sexton - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 被引用: 254
- Fitting Models to Biological Data Using Linear and Nonlinear Regression
著者: Harvey Motulsky, Arthur Christopoulos - 2004 被引用: 1,371
- International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology
著者: Richard R. Neubig, Michael Spedding, Terry Kenakin, Arthur Christopoulos - Pharmacological Reviews 2003 被引用: 660
- Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs
著者: Ron O. Dror, Hillary F. Green, Céline Valant, David W. Borhani, James R. Valcourt, Albert C. Pan, Daniel H. Arlow, Meritxell Canals, J. Robert Lane, Raphaël Rahmani, Jonathan B. Baell, Patrick M. Sexton, Arthur Christopoulos, David E. Shaw - Nature 2013 被引用: 425
