Brian J. Abraham
2011–2024 年に発表
- 63
- 論文数
- 27,753
- 被引用数
- 49
- h 指数
- 61
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology67.8%
- Medicine21.7%
- Immunology and Microbiology5.2%
- Neuroscience1.5%
- Agricultural and Biological Sciences1.2%
- Chemistry0.6%
- その他2%
トピック
- Genomics and Chromatin Dynamics10.5%
- RNA Research and Splicing8.6%
- RNA modifications and cancer5.3%
- Epigenetics and DNA Methylation4.1%
- Protein Degradation and Inhibitors3.6%
- RNA and protein synthesis mechanisms2.8%
- その他65.1%
共著者
- Richard A. Young44
- Tong Ihn Lee15
- A. Thomas Look13
- Adam D. Durbin13
- Mark W. Zimmerman12
- Nathanael S. Gray10
- Nicholas Kwiatkowski10
- Denes Hnisz9
- Tinghu Zhang9
- Nancy M. Hannett8
- Nina Weichert‐Leahey7
- Abraham S. Weintraub6
- Alessandra Dall’Agnese6
- Yang Guo6
- Alicia V. Zamudio5
- Charles H. Li5
- Isaac A. Klein5
- James E. Bradner5
- Jurian Schuijers5
- Lena K. Afeyan5
- Rudolf Jaenisch5
- Ann Boija4
- Benjamin R. Sabari4
- Daniel S. Day4
全論文
- Coactivator condensation at super-enhancers links phase separation and gene control
著者: Benjamin R. Sabari, Alessandra Dall’Agnese, Ann Boija, Isaac A. Klein, Eliot L. Coffey, Krishna Shrinivas, Brian J. Abraham, Nancy M. Hannett, Alicia V. Zamudio, John C. Manteiga, Charles H. Li, Yang Guo, Daniel S. Day, Jurian Schuijers, Eliza Vasile, Sohail Malik, Denes Hnisz, Tong Ihn Lee, Ibrahim I. Cissé, Robert G. Roeder, Phillip A. Sharp, Arup K. Chakraborty, Richard A. Young - Science 2018 被引用: 2,769
- Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
著者: Warren A. Whyte, David A. Orlando, Denes Hnisz, Brian J. Abraham, Charles Y. Lin, Michael H. Kagey, Peter B. Rahl, Tong Ihn Lee, Richard A. Young - Cell 2013 被引用: 4,411
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
著者: Ann Boija, Isaac A. Klein, Benjamin R. Sabari, Alessandra Dall’Agnese, Eliot L. Coffey, Alicia V. Zamudio, Charles H. Li, Krishna Shrinivas, John C. Manteiga, Nancy M. Hannett, Brian J. Abraham, Lena K. Afeyan, Yang Guo, Jenna K. Rimel, Charli B. Fant, Jurian Schuijers, Tong Ihn Lee, Dylan J. Taatjes, Richard A. Young - Cell 2018 被引用: 1,973
- Super-Enhancers in the Control of Cell Identity and Disease
著者: Denes Hnisz, Brian J. Abraham, Tong Ihn Lee, Ashley Lau, Violaine Saint‐André, Alla A. Sigova, Heather A. Hoke, Richard A. Young - Cell 2013 被引用: 3,930
- YY1 Is a Structural Regulator of Enhancer-Promoter Loops
著者: Abraham S. Weintraub, Charles H. Li, Alicia V. Zamudio, Alla A. Sigova, Nancy M. Hannett, Daniel S. Day, Brian J. Abraham, Malkiel A. Cohen, Behnam Nabet, Dennis L. Buckley, Yang Guo, Denes Hnisz, Rudolf Jaenisch, James E. Bradner, Nathanael S. Gray, Richard A. Young - Cell 2017 被引用: 1,099
- Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
著者: Yang Guo, John C. Manteiga, Jonathan E. Henninger, Benjamin R. Sabari, Alessandra Dall’Agnese, Nancy M. Hannett, Jan-Hendrik Spille, Lena K. Afeyan, Alicia V. Zamudio, Krishna Shrinivas, Brian J. Abraham, Ann Boija, Tim-Michael Decker, Jenna K. Rimel, Charli B. Fant, Tong Ihn Lee, Ibrahim I. Cissé, Phillip A. Sharp, Dylan J. Taatjes, Richard A. Young - Nature 2019 被引用: 729
- Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
著者: Nicholas Kwiatkowski, Tinghu Zhang, Peter B. Rahl, Brian J. Abraham, Jessica Reddy, Scott B. Ficarro, Anahita Dastur, Arnaud Amzallag, Sridhar Ramaswamy, Bethany Tesar, Catherine E. Jenkins, Nancy M. Hannett, Douglas W. McMillin, Takaomi Sanda, Taebo Sim, Nam Doo Kim, Thomas Look, Constantine S. Mitsiades, Andrew P. Weng, Jennifer R. Brown, Cyril H. Benes, Jarrod A. Marto, Richard A. Young, Nathanael S. Gray - Nature 2014 被引用: 908
- An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
著者: Marc R. Mansour, Brian J. Abraham, Lars Anders, Alla Berezovskaya, Alejandro Gutiérrez, Adam D. Durbin, Julia Etchin, Lee N. Lawton, Stephen E. Sallan, Lewis B. Silverman, Mignon L. Loh, Stephen P. Hunger, Takaomi Sanda, Richard A. Young, A. Thomas Look - Science 2014 被引用: 829
- EP300 Selectively Controls the Enhancer Landscape of MYCN -Amplified Neuroblastoma
著者: Adam D. Durbin, Tingjian Wang, Virangika K. Wimalasena, Mark W. Zimmerman, Deyao Li, Neekesh V. Dharia, Luca Mariani, Noha A.M. Shendy, Stephanie Nance, Anand G. Patel, Ying Shao, Maya Mundada, Lily Maxham, Paul M.C. Park, Logan H. Sigua, Ken Morita, Amy Saur Conway, Amanda L. Robichaud, Antonio R. Pérez‐Atayde, Melissa J. Bikowitz, Taylor R. Quinn, Olaf Wiest, John Easton, E. Schönbrunn, Martha L. Bulyk, Brian J. Abraham, Kimberly Stegmaier, A. Thomas Look, Jun Qi - Cancer Discovery 2021 被引用: 163
- Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes
著者: Alicia V. Zamudio, Alessandra Dall’Agnese, Jonathan E. Henninger, John C. Manteiga, Lena K. Afeyan, Nancy M. Hannett, Eliot L. Coffey, Charles H. Li, Ozgur Oksuz, Benjamin R. Sabari, Ann Boija, Isaac A. Klein, Susana Wilson Hawken, Jan-Hendrik Spille, Tim-Michael Decker, Ibrahim I. Cissé, Brian J. Abraham, Tong I. Lee, Dylan J. Taatjes, Jurian Schuijers, Richard A. Young - Molecular Cell 2019 被引用: 302
- Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes
著者: Jill M. Dowen, Zi Peng Fan, Denes Hnisz, Gang Ren, Brian J. Abraham, Lyndon N. Zhang, Abraham S. Weintraub, Jurian Schuijers, Tong Ihn Lee, Keji Zhao, Richard A. Young - Cell 2014 被引用: 949
- CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer
著者: Edmond Chipumuro, Eugenio Marco, Camilla L. Christensen, Nicholas Kwiatkowski, Tinghu Zhang, Clark M. Hatheway, Brian J. Abraham, Bandana Sharma, Caleb M. Yeung, Abigail Altabef, Antonio R. Pérez‐Atayde, Kwok‐Kin Wong, Guo‐Cheng Yuan, Nathanael S. Gray, Richard A. Young, Rani E. George - Cell 2014 被引用: 663
- Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers
著者: Denes Hnisz, Jurian Schuijers, Charles Y. Lin, Brian J. Abraham, Tong Ihn Lee, James E. Bradner, Abraham S. Weintraub, Richard A. Young - Molecular Cell 2015 被引用: 506
- CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer
著者: Yubao Wang, Tinghu Zhang, Nicholas Kwiatkowski, Brian J. Abraham, Tong Ihn Lee, Shaozhen Xie, Haluk Yuzugullu, Thanh Von, Heyuan Li, Ziao Lin, Daniel G. Stover, Elgene Lim, Zhigang C. Wang, J. Dirk Iglehart, Richard A. Young, Nathanael S. Gray, Jean J. Zhao - Cell 2015 被引用: 493
- The long noncoding RNA Wisper controls cardiac fibrosis and remodeling
著者: Rudi Micheletti, Isabelle Plaisance, Brian J. Abraham, Alexandre Sarre, Ching-Chia Ting, Michael Alexanian, Daniel Maric, Damien Maison, Mohamed Nemir, Richard A. Young, Blanche Schroen, Arantxa González, Samir Ounzain, Thierry Pedrazzini - Science Translational Medicine 2017 被引用: 337
- Transcription factor trapping by RNA in gene regulatory elements
著者: Alla A. Sigova, Brian J. Abraham, Ji Xiong, Benoit Molinié, Nancy M. Hannett, Yang Guo, Mohini Jangi, Cosmas Giallourakis, Phillip A. Sharp, Richard A. Young - Science 2015 被引用: 527
- Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
著者: Frank Soldner, Yonatan Stelzer, Chikdu Shivalila, Brian J. Abraham, Jeanne C. Latourelle, M. Inmaculada Barrasa, Johanna Goldmann, Richard H. Myers, Richard A. Young, Rudolf Jaenisch - Nature 2016 被引用: 527
- Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
著者: Adam D. Durbin, Mark W. Zimmerman, Neekesh V. Dharia, Brian J. Abraham, Amanda Balboni Iniguez, Nina Weichert‐Leahey, Shuning He, John M. Krill-Burger, David E. Root, Francisca Vázquez, Aviad Tsherniak, William C. Hahn, Todd R. Golub, Richard A. Young, A. Thomas Look, Kimberly Stegmaier - Nature Genetics 2018 被引用: 302
- Models of human core transcriptional regulatory circuitries
著者: Violaine Saint‐André, Alexander Federation, Charles Y. Lin, Brian J. Abraham, Jessica Reddy, Tong Ihn Lee, James E. Bradner, Richard A. Young - Genome Research 2016 被引用: 313
- A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer
著者: Paola Betancur, Brian J. Abraham, Ying Ying Yiu, Stephen B. Willingham, Farnaz Khameneh, Mark A. Zarnegar, Angera H. Kuo, Kelly M. McKenna, Yoko Kojima, Nicholas J. Leeper, Po Y. Ho, Phung Gip, Tomek Swigut, Richard I. Sherwood, Michael F. Clarke, George Somlo, Richard A. Young, Irving L. Weissman - Nature Communications 2017 被引用: 231
- Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
著者: Tinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, Sarah E. Dixon-Clarke, Brian J. Abraham, Ann Katrin Greifenberg, Scott B. Ficarro, Jonathan M. Elkins, Yanke Liang, Nancy M. Hannett, Theresa Manz, Mingfeng Hao, Bartlomiej Bartkowiak, Arno L. Greenleaf, Jarrod A. Marto, Matthias Geyer, Alex N. Bullock, Richard A. Young, Nathanael S. Gray - Nature Chemical Biology 2016 被引用: 372
- MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification
著者: Mark W. Zimmerman, Yu Liu, Shuning He, Adam D. Durbin, Brian J. Abraham, John Easton, Ying Shao, Beisi Xu, Shizhen Zhu, Xiaoling Zhang, Zhaodong Li, Nina Weichert‐Leahey, Richard A. Young, Jinghui Zhang, A. Thomas Look - Cancer Discovery 2017 被引用: 237
- Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas
著者: Victoria Clark, Akdes Serin Harmancı, Hanwen Bai, Mark W. Youngblood, Tong Ihn Lee, Jacob F. Baranoski, A. Gulhan Ercan‐Sencicek, Brian J. Abraham, Abraham S. Weintraub, Denes Hnisz, Matthias Simon, Boris Krischek, E. Zeynep Erson‐Omay, Octavian Henegariu, Geneive Carrión-Grant, Ketu Mishra-Gorur, Daniel Durán, Johanna Goldmann, Johannes Schramm, Roland Goldbrunner, Joseph M. Piepmeier, Alexander O. Vortmeyer, Jennifer Moliterno Günel, Kaya Bilgüvar, Katsuhito Yasuno, Richard A. Young, Murat Günel - Nature Genetics 2016 被引用: 357
- Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor
著者: Camilla L. Christensen, Nicholas Kwiatkowski, Brian J. Abraham, Julián Carretero, Fátima Al‐Shahrour, Tinghu Zhang, Edmond Chipumuro, Grit S. Herter-Sprie, Esra A. Akbay, Abigail Altabef, Jianming Zhang, Takeshi Shimamura, Marzia Capelletti, Jakob B. Reibel, Jillian D. Cavanaugh, Peng Gao, Yan Liu, Signe Regner Michaelsen, Hans Skovgaard Poulsen, Amir Reza Aref, David A. Barbie, James E. Bradner, Rani E. George, Nathanael S. Gray, Richard A. Young, Kwok‐Kin Wong - Cancer Cell 2014 被引用: 458
