litlas
ログインアカウント作成

Channing J. Der

1982–2025 年に発表

240
論文数
56,713
被引用数
127
h 指数
234
i10 指数

被引用数

Channing J. Der の年別被引用数1951 年: 被引用 2 件1979 年: 被引用 1 件1982 年: 被引用 13 件1983 年: 被引用 53 件1984 年: 被引用 60 件1985 年: 被引用 45 件1986 年: 被引用 53 件1987 年: 被引用 45 件1988 年: 被引用 35 件1989 年: 被引用 47 件1990 年: 被引用 111 件1991 年: 被引用 144 件1992 年: 被引用 155 件1993 年: 被引用 141 件1994 年: 被引用 231 件1995 年: 被引用 270 件1996 年: 被引用 263 件1997 年: 被引用 476 件1998 年: 被引用 485 件1999 年: 被引用 672 件2000 年: 被引用 770 件2001 年: 被引用 656 件2002 年: 被引用 658 件2003 年: 被引用 642 件2004 年: 被引用 602 件2005 年: 被引用 584 件2006 年: 被引用 508 件2007 年: 被引用 584 件2008 年: 被引用 471 件2009 年: 被引用 431 件2010 年: 被引用 440 件2011 年: 被引用 448 件2012 年: 被引用 385 件2013 年: 被引用 360 件2014 年: 被引用 405 件2015 年: 被引用 385 件2016 年: 被引用 410 件2017 年: 被引用 408 件2018 年: 被引用 359 件2019 年: 被引用 1,221 件2020 年: 被引用 1,464 件2021 年: 被引用 1,435 件2022 年: 被引用 1,135 件2023 年: 被引用 662 件2024 年: 被引用 1,132 件2025 年: 被引用 669 件2026 年: 被引用 30 件1952〜1978 年は被引用が無いため表示していません1980〜1981 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 7,874 件、この内訳の 40.1%中国: 引用元論文 1,764 件、この内訳の 9%イギリス: 引用元論文 1,134 件、この内訳の 5.8%ドイツ: 引用元論文 1,086 件、この内訳の 5.5%日本: 引用元論文 847 件、この内訳の 4.3%カナダ: 引用元論文 661 件、この内訳の 3.4%フランス: 引用元論文 609 件、この内訳の 3.1%イタリア: 引用元論文 589 件、この内訳の 3%スペイン: 引用元論文 423 件、この内訳の 2.2%オランダ: 引用元論文 382 件、この内訳の 1.9%オーストラリア: 引用元論文 356 件、この内訳の 1.8%韓国: 引用元論文 336 件、この内訳の 1.7%
0%40.1%その他 18.2%

機関

分野

  • Biochemistry, Genetics and Molecular Biology59.3%
  • Medicine29.5%
  • Immunology and Microbiology4.4%
  • Neuroscience2.5%
  • Computer Science0.9%
  • Chemistry0.7%
  • その他2.7%

トピック

  • Protein Kinase Regulation and GTPase Signaling6.7%
  • Melanoma and MAPK Pathways2.8%
  • PI3K/AKT/mTOR signaling in cancer2.5%
  • Cellular Mechanics and Interactions2.4%
  • Cellular transport and secretion2.2%
  • Cancer-related Molecular Pathways2.2%
  • その他81.2%

共著者

全論文

検索で開く
  1. Drugging the undruggable RAS: Mission Possible?

    著者: Adrienne D. Cox, Stephen W. Fesik, Alec C. Kimmelman, Ji Luo, Channing J. Der - Nature Reviews Drug Discovery 2014 被引用: 2,003

  2. Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

    著者: Matthew Holderfield, Bianca J. Lee, Jingjing Jiang, Aidan C.A. Tomlinson, Kyle J. Seamon, Alessia Mira, Enrico Patrucco, Grace Goodhart, Julien Dilly, Yevgeniy Gindin, Nuntana Dinglasan, Yingyun Wang, Lo Lai, Shurui Cai, Lingyan Jiang, Nicole Nasholm, Nataliya Tovbis Shifrin, Cristina Blaj, Harshit Shah, James Evans, Nilufar Montazer, Oliver Lai, Jade Shi, Ethan Ahler, Elsa Quintana, Stephanie Chang, Anthony Salvador, Abby Marquez, Jim Cregg, Yang Liu, Anthony N. Milin, Anqi Chen, Tamar Bar Ziv, Dylan Parsons, John E. Knox, Jennifer E. Klomp, Jennifer A. Roth, Matthew G. Rees, Melissa M. Ronan, Antonio Cuevas-Navarro, Feng Hu, Piro Lito, David Santamarı́a, Andrew J. Aguirre, Andrew M. Waters, Channing J. Der, Chiara Ambrogio, Zhengping Wang, Adrian L. Gill, Elena S. Koltun, Jacqueline A.M. Smith, David Wildes, Mallika Singh - Nature 2024 被引用: 318

  3. KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer

    著者: Andrew M. Waters, Channing J. Der - Cold Spring Harbor Perspectives in Medicine 2017 被引用: 866

  4. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

    著者: Patrick J. Roberts, Channing J. Der - Oncogene 2007 被引用: 2,796

  5. Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

    著者: Yingxue Wang, Daniel Zeitouni, Clint A. Stalnecker, Haoqiang Ying, Erik S. Knudsen, Guofang Zhang, Pankaj K. Singh, Agnieszka K. Witkiewicz, Venugopal Gunda, Andrey P. Tikunov, Adrienne D. Cox, Garima Tomar, Sen Peng, Jennifer E. Klomp, Andrew M. Waters, Mariaelena Pierobon, J. Nathaniel Diehl, Tikvah K. Hayes, Yan Liang, G. Aaron Hobbs, Emanuel F. Petricoin, Channing J. Der, Jeffrey M. Macdonald, Costas A. Lyssiotis, Alec C. Kimmelman, Gennifer D. Goode, Samuel D. George, Nhan L. Tran, Kirsten L. Bryant, Bjoern Papke, Nina V. Chaika - Nature Medicine 2019 被引用: 715

  6. RAS isoforms and mutations in cancer at a glance

    著者: G. Aaron Hobbs, Channing J. Der, Kent L. Rossman - Journal of Cell Science 2016 被引用: 991

  7. Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

    著者: Urszula N. Wasko, Jingjing Jiang, Tanner C. Dalton, Álvaro Curiel‐García, A. Cole Edwards, Yingyun Wang, Bianca J. Lee, Margo Orlen, Sha Tian, Clint A. Stalnecker, Kristina Drizyte‐Miller, Marie Ménard, Julien Dilly, Stephen A. Sastra, Carmine F. Palermo, Marie C. Hasselluhn, Amanda R. Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu Chi Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B. Kemp, Cynthia Clendenin, Rina Sor, William P. Vostrejs, Priya S. Hibshman, Amber M. Amparo, Connor J. Hennessey, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D. Socci, Laura E. Herring, Natalie K. Barker, Junning Wang, James M. Cleary, Brian M. Wolpin, John A. Chabot, Michael D. Kluger, Gulam A. Manji, Kenneth Y. Tsai, Miroslav Sekulic, Stephen M. Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A.M. Smith, Matthew Holderfield, David Wildes, Scott W. Lowe, Michael A. Badgley, Andrew J. Aguirre, Robert H. Vonderheide, Ben Z. Stanger, Timour Baslan, Channing J. Der, Mallika Singh, Kenneth P. Olive - Nature 2024 被引用: 175

  8. KRAS: feeding pancreatic cancer proliferation

    著者: Kirsten L. Bryant, Joseph D. Mancias, Alec C. Kimmelman, Channing J. Der - Trends in Biochemical Sciences 2014 被引用: 684

  9. Combination Therapies with CDK4/6 Inhibitors to Treat KRAS- Mutant Pancreatic Cancer

    著者: Craig M. Goodwin, Andrew M. Waters, Jennifer E. Klomp, Sehrish Javaid, Kirsten L. Bryant, Clint A. Stalnecker, Kristina Drizyte‐Miller, Bjoern Papke, Runying Yang, Amber M. Amparo, Irem Ozkan‐Dagliyan, Elisa Baldelli, Valerie Calvert, Mariaelena Pierobon, Jessica A. Sorrentino, Andrew P. Beelen, Natalie Bublitz, Mareen Lüthen, Kris C. Wood, Emanuel F. Petricoin, Christine Sers, Autumn J. McRee, Adrienne D. Cox, Channing J. Der - Cancer Research 2022 被引用: 160

  10. The Ras superfamily at a glance

    著者: Krister Wennerberg, Kent L. Rossman, Channing J. Der - Journal of Cell Science 2005 被引用: 1,531

  11. Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

    著者: G. Aaron Hobbs, Nicole M. Baker, Anne M. Miermont, Ryan D. Thurman, Mariaelena Pierobon, Timothy H. Tran, Andrew O. Anderson, Andrew M. Waters, J. Nathaniel Diehl, Bjoern Papke, Richard G. Hodge, Jennifer E. Klomp, Craig M. Goodwin, Jonathan M. DeLiberty, Junning Wang, Raymond W.S. Ng, Prson Gautam, Kirsten L. Bryant, Dominic Esposito, Sharon L. Campbell, Emanuel F. Petricoin, Dhirendra K. Simanshu, Andrew J. Aguirre, Brian M. Wolpin, Krister Wennerberg, Udo Rudloff, Adrienne D. Cox, Channing J. Der - Cancer Discovery 2019 被引用: 226

  12. Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

    著者: Dominico Vigil, Jacqueline Cherfils, Kent L. Rossman, Channing J. Der - Nature reviews. Cancer 2010 被引用: 816

  13. Ras history

    著者: Adrienne D. Cox, Channing J. Der - Small GTPases 2010 被引用: 713

  14. Drugging RAS: Know the enemy

    著者: Bjoern Papke, Channing J. Der - Science 2017 被引用: 395

  15. KRAS inhibitors: resistance drivers and combinatorial strategies

    著者: Tamara Isermann, Christine Sers, Channing J. Der, Bjoern Papke - Trends in cancer 2024 被引用: 157

  16. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

    著者: Angelina V. Vaseva, Devon R. Blake, Thomas S.K. Gilbert, Serina Ng, Galen Hostetter, Salma H. Azam, Irem Ozkan‐Dagliyan, Prson Gautam, Kirsten L. Bryant, Kenneth H. Pearce, Laura E. Herring, Haiyong Han, Lee M. Graves, Agnieszka K. Witkiewicz, Erik S. Knudsen, Chad V. Pecot, Naim U. Rashid, Peter J. Houghton, Krister Wennerberg, Adrienne D. Cox, Channing J. Der - Cancer Cell 2018 被引用: 192

  17. Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer

    著者: Luisa F. Escobar‐Hoyos, Alex Penson, Ram Kannan, Hana Cho, Chun‐Hao Pan, Rohit K. Singh, Lisa Helene Apken, G. Aaron Hobbs, Renhe Luo, Nicolas Lecomte, Sruthi Babu, Fong Cheng Pan, Direna Alonso‐Curbelo, John P. Morris, Gökçe Aşkan, Olivera Grbovic-Huezo, Paul Ogrodowski, Jonathan Bermeo, Joseph A. Saglimbeni, Cristian D. Cruz, Yu-Jui Ho, Sharon Lawrence, Jerry P. Melchor, Grant A. Goda, Karen Bai, Alessandro Pastore, Simon J. Hogg, Srivatsan Raghavan, Peter J. Bailey, David K. Chang, Andrew V. Biankin, Kenneth R. Shroyer, Brian M. Wolpin, Andrew J. Aguirre, Andrea Ventura, Barry S. Taylor, Channing J. Der, Daniel Domínguez, Daniel Kümmel, Andrea Oeckinghaus, Scott W. Lowe, Robert K. Bradley, Omar Abdel‐Wahab, Steven D. Leach - Cancer Cell 2020 被引用: 158

  18. TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors

    著者: A. Cole Edwards, Clint A. Stalnecker, Alexis Jean Morales, Khalilah E. Taylor, Jennifer E. Klomp, Jeffrey A. Klomp, Andrew M. Waters, Niranjan Sudhakar, Jill Hallin, Tracy T. Tang, Peter Olson, Leonard Post, James G. Christensen, Adrienne D. Cox, Channing J. Der - Cancer Research 2023 被引用: 80

  19. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

    著者: Kent L. Rossman, Channing J. Der, John Sondek - Nature Reviews Molecular Cell Biology 2005 被引用: 1,722

  20. Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

    著者: Haisheng Zhang, Antje Schaefer, Yichen Wang, Richard G. Hodge, Devon R. Blake, J. Nathaniel Diehl, Alex G. Papageorge, Matthew D. Stachler, Jennifer Liao, Jin Zhou, Zhong Wu, Fahire G. Akarca, Leonie K. de Klerk, Sarah Derks, Mariaelena Pierobon, Katherine A. Hoadley, Timothy C. Wang, George M. Church, Kwok‐Kin Wong, Emanuel F. Petricoin, Adrienne D. Cox, Douglas R. Lowy, Channing J. Der, Adam J. Bass - Cancer Discovery 2019 被引用: 173

  21. Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers

    著者: Jeffrey A. Klomp, Jeffrey A. Klomp, Jennifer E. Klomp, Jennifer E. Klomp, Clint A. Stalnecker, Kirsten L. Bryant, A. Cole Edwards, Kristina Drizyte‐Miller, Priya S. Hibshman, J. Nathaniel Diehl, Ye S. Lee, Alexis Jean Morales, Khalilah E. Taylor, Sen Peng, Nhan L. Tran, Laura E. Herring, Alex W. Prevatte, Natalie K. Barker, Laura D. Hover, Jill Hallin, Saikat Chowdhury, Oluwadara Coker, Hey Min Lee, Craig M. Goodwin, Prson Gautam, Peter Olson, James G. Christensen, John Paul Shen, Scott Kopetz, Lee M. Graves, Kian‐Huat Lim, Andrea Wang‐Gillam, Krister Wennerberg, Adrienne D. Cox, Channing J. Der - Science 2024 被引用: 108

  22. Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

    著者: Tikvah K. Hayes, Nicole F. Neel, Chaoxin Hu, Prson Gautam, Mélissa Chénard, Brian J. Long, Meraj Aziz, Michelle Kassner, Kirsten L. Bryant, Mariaelena Pierobon, Raoud Marayati, Swapnil S. Kher, Samuel D. George, Ming Xu, Andrea Wang‐Gillam, Ahmed A. Samatar, Anirban Maitra, Krister Wennerberg, Emanuel F. Petricoin, Hongwei Yin, Barry D. Nelkin, Adrienne D. Cox, Jen Jen Yeh, Channing J. Der - Cancer Cell 2015 被引用: 275

  23. Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer

    著者: Jennifer E. Klomp, J. Nathaniel Diehl, Jeffrey A. Klomp, A. Cole Edwards, Runying Yang, Alexis Jean Morales, Khalilah E. Taylor, Kristina Drizyte‐Miller, Kirsten L. Bryant, Antje Schaefer, Jared L. Johnson, Emily M. Huntsman, Tomer M. Yaron, Mariaelena Pierobon, Elisa Baldelli, Alex W. Prevatte, Natalie K. Barker, Laura E. Herring, Emanuel F. Petricoin, Lee M. Graves, Lewis C. Cantley, Adrienne D. Cox, Channing J. Der, Clint A. Stalnecker - Science 2024 被引用: 81

  24. Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

    著者: Kaikobad Irani, Yong Xia, Jay L. Zweíer, Steven J. Sollott, Channing J. Der, Eric R. Fearon, Maitrayee Sundaresan, Toren Finkel, Pascal J. Goldschmidt‐Clermont - Science 1997 被引用: 1,593