Charles A. Gersbach
2004–2025 年に発表
- 87
- 論文数
- 21,962
- 被引用数
- 65
- h 指数
- 81
- i10 指数
被引用数
引用元
国・地域
機関
- Harvard University1.4%
- Howard Hughes Medical Institute0.9%
- Chinese Academy of Sciences0.9%
- Duke University0.8%
- Stanford University0.8%
- Broad Institute0.7%
- その他94.5%
分野
- Biochemistry, Genetics and Molecular Biology79.1%
- Medicine11.1%
- Neuroscience2.5%
- Agricultural and Biological Sciences2.4%
- Engineering1.5%
- Immunology and Microbiology1.4%
- その他2%
トピック
- CRISPR and Genetic Engineering19.3%
- RNA Interference and Gene Delivery4.1%
- Advanced biosensing and bioanalysis techniques3.8%
- Virus-based gene therapy research3.8%
- RNA and protein synthesis mechanisms3.7%
- Pluripotent Stem Cells Research2.9%
- その他62.4%
共著者
- Timothy E. Reddy16
- Gregory E. Crawford14
- Alejandro Barrera13
- Aravind Asokan10
- David G. Ousterout10
- Pratiksha I. Thakore10
- Farshid Guilak9
- Ami M. Kabadi8
- Christopher E. Nelson8
- Pablo Pérez‐Piñera8
- Alexias Safi7
- Lingyun Song7
- Christopher M. Vockley6
- D. Dewran Koçak6
- Isaac B. Hilton6
- Jonathan M. Brunger6
- Joshua B. Black6
- Nahid Iglesias6
- William H. Majoros6
- Adrian Pickar‐Oliver5
- Andrés J. Garcı́a5
- Anthony D’Ippolito5
- Lexi R. Bounds5
- Luke C. Bartelt5
全論文
- The next generation of CRISPR–Cas technologies and applications
著者: Adrian Pickar‐Oliver, Charles A. Gersbach - Nature Reviews Molecular Cell Biology 2019 被引用: 1,493
- ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
著者: Thomas Gaj, Charles A. Gersbach, Carlos F. Barbas - Trends in biotechnology 2013 被引用: 3,774
- Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
著者: Isaac B. Hilton, Anthony D’Ippolito, Christopher M. Vockley, Pratiksha I. Thakore, Gregory E. Crawford, Timothy E. Reddy, Charles A. Gersbach - Nature Biotechnology 2015 被引用: 1,876
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
著者: Pablo Pérez‐Piñera, D. Dewran Koçak, Christopher M. Vockley, Andrew F. Adler, Ami M. Kabadi, Lauren R. Polstein, Pratiksha I. Thakore, Katherine A. Glass, David G. Ousterout, Kam W. Leong, Farshid Guilak, Gregory E. Crawford, Timothy E. Reddy, Charles A. Gersbach - Nature Methods 2013 被引用: 1,349
- Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
著者: Pratiksha I. Thakore, Anthony D’Ippolito, Lingyun Song, Alexias Safi, Nishkala K. Shivakumar, Ami M. Kabadi, Timothy E. Reddy, Gregory E. Crawford, Charles A. Gersbach - Nature Methods 2015 被引用: 1,045
- The once and future gene therapy
著者: Karen Bulaklak, Charles A. Gersbach - Nature Communications 2020 被引用: 322
- In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
著者: Christopher E. Nelson, Chady H. Hakim, David G. Ousterout, Pratiksha I. Thakore, Eirik A. Moreb, Ruth M. Castellanos Rivera, Sarina Madhavan, Xiufang Pan, F. Ann Ran, Winston X. Yan, Aravind Asokan, Feng Zhang, Dongsheng Duan, Charles A. Gersbach - Science 2015 被引用: 1,152
- Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
著者: Christopher E. Nelson, Yaoying Wu, Matthew Gemberling, Matthew L. Oliver, Matthew A. Waller, Joel D. Bohning, Jacqueline N. Robinson-Hamm, Karen Bulaklak, Ruth M. Castellanos Rivera, Joel H. Collier, Aravind Asokan, Charles A. Gersbach - Nature Medicine 2019 被引用: 429
- Increasing the specificity of CRISPR systems with engineered RNA secondary structures
著者: D. Dewran Koçak, Eric A. Josephs, Vidit Bhandarkar, Shaunak Adkar, Jennifer B. Kwon, Charles A. Gersbach - Nature Biotechnology 2019 被引用: 361
- Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models
著者: Chady H. Hakim, Sandeep Kumar, Dennis O. Pérez‐López, Nalinda B. Wasala, Dong Zhang, Yongping Yue, James Teixeira, Xiufang Pan, Keqing Zhang, Emily D. Million, Christopher E. Nelson, Samantha Metzger, Jin-Young Han, Jacqueline A. Louderman, Florian Schmidt, Feng Feng, Dirk Grimm, B. F. Smith, Gang Yao, N. Nora Yang, Charles A. Gersbach, Shi‐Jie Chen, Roland W. Herzog, Dongsheng Duan - Nature Communications 2021 被引用: 170
- Editing the epigenome: technologies for programmable transcription and epigenetic modulation
著者: Pratiksha I. Thakore, Joshua B. Black, Isaac B. Hilton, Charles A. Gersbach - Nature Methods 2016 被引用: 448
- Genome-editing Technologies for Gene and Cell Therapy
著者: Morgan L. Maeder, Charles A. Gersbach - Molecular Therapy 2016 被引用: 718
- A light-inducible CRISPR-Cas9 system for control of endogenous gene activation
著者: Lauren R. Polstein, Charles A. Gersbach - Nature Chemical Biology 2015 被引用: 651
- CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
著者: Tyler S. Klann, Joshua B. Black, Malathi Chellappan, Alexias Safi, Lingyun Song, Isaac B. Hilton, Gregory E. Crawford, Timothy E. Reddy, Charles A. Gersbach - Nature Biotechnology 2017 被引用: 470
- Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens
著者: Sean R. McCutcheon, Adam M. Swartz, Michael C. Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka, Lucas Humayun, Maria A. ter Weele, James Isaacs, Timothy E. Reddy, Andrew S. Allen, Smita K. Nair, Scott J. Antonia, Charles A. Gersbach - Nature Genetics 2023 被引用: 78
- Transgenic mice for in vivo epigenome editing with CRISPR-based systems
著者: Matthew Gemberling, Keith Siklenka, Erica Rodriguez, Katherine R. Tonn Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F. Hazlett, Courtney Williams, Luke C. Bartelt, Victoria J. Madigan, Josephine C. Bodle, Heather Daniels, Douglas Rouse, Isaac B. Hilton, Aravind Asokan, Maria Ciofani, Kenneth D. Poss, Timothy E. Reddy, Anne E. West, Charles A. Gersbach - Nature Methods 2021 被引用: 138
- Epigenome editing technologies for discovery and medicine
著者: Sean R. McCutcheon, Dahlia Rohm, Nahid Iglesias, Charles A. Gersbach - Nature Biotechnology 2024 被引用: 95
- Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing
著者: Trevor Gonzalez, Katherine E. Simon, Leo O. Blondel, Marco M. Fanous, Angela L. Roger, Maribel Santiago Maysonet, Garth Devlin, Timothy J. Smith, Daniel K. Oh, L. Patrick Havlik, Ruth M. Castellanos Rivera, Jorge A. Piedrahita, Mai K. ElMallah, Charles A. Gersbach, Aravind Asokan - Nature Communications 2022 被引用: 81
- Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector
著者: Ami M. Kabadi, David G. Ousterout, Isaac B. Hilton, Charles A. Gersbach - Nucleic Acids Research 2014 被引用: 388
- RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
著者: Pratiksha I. Thakore, Jennifer B. Kwon, Christopher E. Nelson, Douglas Rouse, Matthew Gemberling, Matthew L. Oliver, Charles A. Gersbach - Nature Communications 2018 被引用: 174
- Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes
著者: Liang-Fu Chen, Yen Ting Lin, David A. Gallegos, Mariah F. Hazlett, Mariana Gómez-Schiavon, Marty G. Yang, Breanna Kalmeta, Allen S. Zhou, Liad Holtzman, Charles A. Gersbach, Jörg Grandl, Nicolas E. Buchler, Anne E. West - Cell Reports 2019 被引用: 177
- Multicenter integrated analysis of noncoding CRISPRi screens
著者: David Yao, Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis, Ava Mackay-Smith, Benjamin R. Doughty, Idan Gabdank, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D. White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J. Greenleaf, Pardis C. Sabeti, Christina S. Leslie, Yuri Pritykin, Jill E. Moore, M Beer, Charles A. Gersbach, Timothy E. Reddy, Yin Shen, J Engreitz, Michael C. Bassik, Steven K. Reilly - Nature Methods 2024 被引用: 50
- Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy
著者: Adrian Pickar‐Oliver, Veronica Gough, Joel D. Bohning, Siyan Liu, Jacqueline N. Robinson-Hamm, Heather Daniels, William H. Majoros, Garth Devlin, Aravind Asokan, Charles A. Gersbach - Molecular Therapy 2021 被引用: 67
- Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart
著者: Jacquelyn M. Walejko, Bridgette A. Christopher, Scott B. Crown, Guofang Zhang, Adrian Pickar‐Oliver, Takeshi Yoneshiro, Matthew W. Foster, Stephani C. Page, Stephan van Vliet, Olga Ilkayeva, Michael J. Muehlbauer, Matthew W. Carson, Joseph T. Brozinick, Craig D. Hammond, Ruth E. Gimeno, M. Arthur Moseley, Shingo Kajimura, Charles A. Gersbach, Christopher B. Newgard, Phillip J. White, Robert W. McGarrah - Nature Communications 2021 被引用: 97
