Christopher M. Dobson
1973–2024 年に発表
- 別表記
- Christopher M Dobson
- 469
- 論文数
- 113,744
- 被引用数
- 169
- h 指数
- 469
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology43.1%
- Medicine33.6%
- Materials Science6.1%
- Chemistry3.9%
- Neuroscience2.9%
- Computer Science2.3%
- その他8.1%
トピック
- Protein Structure and Dynamics9.7%
- Alzheimer's disease research and treatments9.7%
- Enzyme Structure and Function4.5%
- Parkinson's Disease Mechanisms and Treatments3.5%
- Computational Drug Discovery Methods2.9%
- Prion Diseases and Protein Misfolding2.4%
- その他67.3%
共著者
- Michele Vendruscolo144
- Tuomas P. J. Knowles109
- Fabrizio Chiti51
- Sara Linse34
- Janet R. Kumita31
- Carol V. Robinson30
- Georg Meisl29
- Alexander K. Buell28
- David Klenerman28
- Samuel I. A. Cohen27
- Nunilo Cremades25
- John Christodoulou24
- Michele Perni22
- Christina Redfield21
- Sheena E. Radford21
- Thomas C. T. Michaels21
- Jesús Zurdo20
- Mark R. Wilson20
- Paolo Arosio20
- Patrick Flagmeier20
- Cait E. MacPhee19
- Francesco A. Aprile18
- Mark E. Welland18
- Serene W. Chen18
全論文
- Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
著者: Fabrizio Chiti, Christopher M. Dobson - Annual Review of Biochemistry 2017 被引用: 2,684
- Protein Misfolding, Functional Amyloid, and Human Disease
著者: Fabrizio Chiti, Christopher M. Dobson - Annual Review of Biochemistry 2006 被引用: 6,418
- The amyloid state and its association with protein misfolding diseases
著者: Tuomas P. J. Knowles, Michele Vendruscolo, Christopher M. Dobson - Nature Reviews Molecular Cell Biology 2014 被引用: 2,412
- Protein folding and misfolding
著者: Christopher M. Dobson - Nature 2003 被引用: 4,779
- Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism
著者: Samuel I. A. Cohen, Sara Linse, Leila M. Luheshi, Erik Hellstrand, Duncan A. White, Luke Rajah, Daniel E. Otzen, Michele Vendruscolo, Christopher M. Dobson, Tuomas P. J. Knowles - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 被引用: 1,447
- Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
著者: Giuliana Fusco, Serene W. Chen, Philip T. F. Williamson, Roberta Cascella, Michele Perni, James A. Jarvis, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti, Nunilo Cremades, Liming Ying, Christopher M. Dobson, Alfonso De Simone - Science 2017 被引用: 703
- Molecular mechanisms of protein aggregation from global fitting of kinetic models
著者: Georg Meisl, Julius B. Kirkegaard, Paolo Arosio, Thomas C. T. Michaels, Michele Vendruscolo, Christopher M. Dobson, Sara Linse, Tuomas P. J. Knowles - Nature Protocols 2016 被引用: 789
- Half a century of amyloids: past, present and future
著者: Pu Chun Ke, Ruhong Zhou, Louise C. Serpell, Roland Riek, Tuomas P. J. Knowles, Hilal A. Lashuel, Ehud Gazit, Ian W. Hamley, Thomas P. Davis, Marcus Fändrich, Daniel E. Otzen, Matthew R. Chapman, Christopher M. Dobson, David Eisenberg, Raffaele Mezzenga - Chemical Society Reviews 2020 被引用: 577
- Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
著者: Céline Galvagnion, Alexander K. Buell, Georg Meisl, Thomas C. T. Michaels, Michele Vendruscolo, Tuomas P. J. Knowles, Christopher M. Dobson - Nature Chemical Biology 2015 被引用: 685
- Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
著者: Alexander K. Buell, Céline Galvagnion, Ricardo Gaspar, Emma Sparr, Michele Vendruscolo, Tuomas P. J. Knowles, Sara Linse, Christopher M. Dobson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 被引用: 687
- Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
著者: Nunilo Cremades, Samuel I. A. Cohen, Emma Deas, Andrey Y. Abramov, Allen Y. Chen, Ángel Orte, Massimo Sandal, Richard W. Clarke, Paul Dunne, Francesco A. Aprile, Carlos W. Bertoncini, Nicholas Wood, Tuomas P. J. Knowles, Christopher M. Dobson, David Klenerman - Cell 2012 被引用: 918
- Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
著者: Thomas C. T. Michaels, Anđela Šarić, Samo Curk, Katja Bernfur, Paolo Arosio, Georg Meisl, Alexander J. Dear, Samuel I. A. Cohen, Christopher M. Dobson, Michele Vendruscolo, Sara Linse, Tuomas P. J. Knowles - Nature Chemistry 2020 被引用: 343
- An Analytical Solution to the Kinetics of Breakable Filament Assembly
著者: Tuomas P. J. Knowles, Christopher A. Waudby, Glyn L. Devlin, Samuel I. A. Cohen, Adriano Aguzzi, Michele Vendruscolo, Eugene M. Terentjev, Mark E. Welland, Christopher M. Dobson - Science 2009 被引用: 1,158
- Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies
著者: Sara Linse, Tom Scheidt, Katja Bernfur, Michele Vendruscolo, Christopher M. Dobson, Samuel I. A. Cohen, Eimantas Šileikis, Martin Lundqvist, Fang Qian, Tiernan T. O’Malley, Thierry Bussière, Paul H. Weinreb, Catherine K. Xu, Georg Meisl, Sean R. A. Devenish, Tuomas P. J. Knowles, Oskar Hansson - Nature Structural & Molecular Biology 2020 被引用: 197
- Widespread Proteome Remodeling and Aggregation in Aging C. elegans
著者: Dirk Walther, Prasad Kasturi, Min Zheng, Stefan Pinkert, Giulia Vecchi, Prajwal Ciryam, Richard I. Morimoto, Christopher M. Dobson, Michele Vendruscolo, Matthias Mann, F. Ulrich Hartl - Cell 2015 被引用: 606
- Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides
著者: Georg Meisl, Xiaoting Yang, Erik Hellstrand, Birgitta Frohm, Julius B. Kirkegaard, Samuel I. A. Cohen, Christopher M. Dobson, Sara Linse, Tuomas P. J. Knowles - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 被引用: 513
- Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
著者: Giuliana Fusco, Alfonso De Simone, Tata Gopinath, Vitaly V. Vostrikov, Michele Vendruscolo, Christopher M. Dobson, Gianluigi Veglia - Nature Communications 2014 被引用: 478
- Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
著者: Gabriella T. Heller, Francesco A. Aprile, Thomas C. T. Michaels, Ryan Limbocker, Michele Perni, Francesco Simone Ruggeri, Benedetta Mannini, Thomas Löhr, Massimiliano Bonomi, Carlo Camilloni, Alfonso De Simone, Isabella C. Felli, Roberta Pierattelli, Tuomas P. J. Knowles, Christopher M. Dobson, Michele Vendruscolo - Science Advances 2020 被引用: 181
- The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells
著者: Roberta Cascella, Serene W. Chen, Alessandra Bigi, José D. Camino, Catherine K. Xu, Christopher M. Dobson, Fabrizio Chiti, Nunilo Cremades, Cristina Cecchi - Nature Communications 2021 被引用: 240
- Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation
著者: Patrick Flagmeier, Georg Meisl, Michele Vendruscolo, Tuomas P. J. Knowles, Christopher M. Dobson, Alexander K. Buell, Céline Galvagnion - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 349
- Chemical space and biology
著者: Christopher M. Dobson - Nature 2004 被引用: 1,035
- Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease
著者: Emma Deas, Nunilo Cremades, Plamena R. Angelova, Marthe H. R. Ludtmann, Zhi Yao, Serene W. Chen, Mathew H. Horrocks, Blerida Banushi, Daniel Little, Michael J. Devine, Paul Gissen, David Klenerman, Christopher M. Dobson, Nicholas Wood, Sonia Gandhi, Andrey Y. Abramov - Antioxidants and Redox Signaling 2015 被引用: 362
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
著者: Samuel I. A. Cohen, Paolo Arosio, Jenny Presto, Firoz Roshan Kurudenkandy, Henrik Biverstål, Lisa Dolfe, Christopher J.R. Dunning, Xiaoting Yang, Birgitta Frohm, Michele Vendruscolo, Jan Johansson, Christopher M. Dobson, André Fisahn, Tuomas P. J. Knowles, Sara Linse - Nature Structural & Molecular Biology 2015 被引用: 424
- Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
著者: Céline Galvagnion, James W. Brown, Myriam Ouberaï, Patrick Flagmeier, Michele Vendruscolo, Alexander K. Buell, Emma Sparr, Christopher M. Dobson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 320
