litlas
ログインアカウント作成

Fabrizio Chiti

1998–2025 年に発表

96
論文数
26,179
被引用数
65
h 指数
93
i10 指数

被引用数

Fabrizio Chiti の年別被引用数1962 年: 被引用 1 件1974 年: 被引用 1 件1981 年: 被引用 1 件1998 年: 被引用 1 件1999 年: 被引用 22 件2000 年: 被引用 43 件2001 年: 被引用 56 件2002 年: 被引用 107 件2003 年: 被引用 146 件2004 年: 被引用 229 件2005 年: 被引用 233 件2006 年: 被引用 213 件2007 年: 被引用 296 件2008 年: 被引用 300 件2009 年: 被引用 369 件2010 年: 被引用 308 件2011 年: 被引用 348 件2012 年: 被引用 300 件2013 年: 被引用 279 件2014 年: 被引用 301 件2015 年: 被引用 244 件2016 年: 被引用 222 件2017 年: 被引用 245 件2018 年: 被引用 247 件2019 年: 被引用 900 件2020 年: 被引用 906 件2021 年: 被引用 808 件2022 年: 被引用 600 件2023 年: 被引用 438 件2024 年: 被引用 666 件2025 年: 被引用 288 件2026 年: 被引用 8 件1963〜1973 年は被引用が無いため表示していません1975〜1980 年は被引用が無いため表示していません1982〜1997 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 2,077 件、この内訳の 22.9%イギリス: 引用元論文 955 件、この内訳の 10.5%中国: 引用元論文 597 件、この内訳の 6.6%ドイツ: 引用元論文 563 件、この内訳の 6.2%イタリア: 引用元論文 545 件、この内訳の 6%インド: 引用元論文 421 件、この内訳の 4.7%スウェーデン: 引用元論文 294 件、この内訳の 3.2%スペイン: 引用元論文 279 件、この内訳の 3.1%日本: 引用元論文 252 件、この内訳の 2.8%フランス: 引用元論文 245 件、この内訳の 2.7%カナダ: 引用元論文 229 件、この内訳の 2.5%スイス: 引用元論文 222 件、この内訳の 2.5%
0%22.9%その他 26.3%

機関

分野

  • Medicine46.7%
  • Biochemistry, Genetics and Molecular Biology37.8%
  • Materials Science4.9%
  • Neuroscience3.1%
  • Agricultural and Biological Sciences1.7%
  • Chemistry1.7%
  • その他4.1%

トピック

  • Alzheimer's disease research and treatments15.8%
  • Protein Structure and Dynamics9.3%
  • Prion Diseases and Protein Misfolding4.6%
  • Parkinson's Disease Mechanisms and Treatments4.1%
  • Enzyme Structure and Function3.1%
  • Computational Drug Discovery Methods3.1%
  • その他60%

共著者

全論文

検索で開く
  1. Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade

    著者: Fabrizio Chiti, Christopher M. Dobson - Annual Review of Biochemistry 2017 被引用: 2,684

  2. Protein Misfolding, Functional Amyloid, and Human Disease

    著者: Fabrizio Chiti, Christopher M. Dobson - Annual Review of Biochemistry 2006 被引用: 6,418

  3. Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

    著者: Giuliana Fusco, Serene W. Chen, Philip T. F. Williamson, Roberta Cascella, Michele Perni, James A. Jarvis, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti, Nunilo Cremades, Liming Ying, Christopher M. Dobson, Alfonso De Simone - Science 2017 被引用: 703

  4. The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

    著者: Roberta Cascella, Serene W. Chen, Alessandra Bigi, José D. Camino, Catherine K. Xu, Christopher M. Dobson, Fabrizio Chiti, Nunilo Cremades, Cristina Cecchi - Nature Communications 2021 被引用: 240

  5. Misfolded protein oligomers: mechanisms of formation, cytotoxic effects, and pharmacological approaches against protein misfolding diseases

    著者: Dillon J. Rinauro, Fabrizio Chiti, Michele Vendruscolo, Ryan Limbocker - Molecular Neurodegeneration 2024 被引用: 110

  6. A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

    著者: Michele Perni, Céline Galvagnion, Alexander S. Maltsev, Georg Meisl, Martin Müller, Pavan K. Challa, Julius B. Kirkegaard, Patrick Flagmeier, Samuel I. A. Cohen, Roberta Cascella, Serene W. Chen, Ryan Limbocker, Pietro Sormanni, Gabriella T. Heller, Francesco A. Aprile, Nunilo Cremades, Cristina Cecchi, Fabrizio Chiti, Ellen A. A. Nollen, Tuomas P. J. Knowles, Michele Vendruscolo, Ad Bax, Michael Zasloff, Christopher M. Dobson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 被引用: 299

  7. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

    著者: Monica Bucciantini, Elisa Giannoni, Fabrizio Chiti, Fabiana Baroni, Lucia Formigli, Jesús Zurdo, Niccolò Taddei, Giampietro Ramponi, Christopher M. Dobson, Massimo Stefani - Nature 2002 被引用: 2,455

  8. Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors

    著者: Giulia Fani, Benedetta Mannini, Giulia Vecchi, Roberta Cascella, Cristina Cecchi, Christopher M. Dobson, Michele Vendruscolo, Fabrizio Chiti - ACS Chemical Neuroscience 2021 被引用: 89

  9. Rationalization of the effects of mutations on peptide andprotein aggregation rates

    著者: Fabrizio Chiti, Massimo Stefani, Niccolò Taddei, Giampietro Ramponi, Christopher M. Dobson - Nature 2003 被引用: 1,078

  10. Amyloid formation by globular proteins under native conditions

    著者: Fabrizio Chiti, Christopher M. Dobson - Nature Chemical Biology 2008 被引用: 817

  11. A causative link between the structure of aberrant protein oligomers and their toxicity

    著者: Silvia Campioni, Benedetta Mannini, Mariagioia Zampagni, Anna Pensalfini, Claudia Parrini, Elisa Evangelisti, Annalisa Relini, Massimo Stefani, Christopher M. Dobson, Cristina Cecchi, Fabrizio Chiti - Nature Chemical Biology 2010 被引用: 550

  12. Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes

    著者: Ryan Limbocker, Sean Chia, Francesco Simone Ruggeri, Michele Perni, Roberta Cascella, Gabriella T. Heller, Georg Meisl, Benedetta Mannini, Johnny Habchi, Thomas C. T. Michaels, Pavan K. Challa, Minkoo Ahn, Samuel Casford, Nilumi Fernando, Catherine K. Xu, Nina Kloss, Samuel I. A. Cohen, Janet R. Kumita, Cristina Cecchi, Michael Zasloff, Sara Linse, Tuomas P. J. Knowles, Fabrizio Chiti, Michele Vendruscolo, Christopher M. Dobson - Nature Communications 2019 被引用: 151

  13. Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

    著者: Michele Perni, Patrick Flagmeier, Ryan Limbocker, Roberta Cascella, Francesco A. Aprile, Céline Galvagnion, Gabriella T. Heller, Georg Meisl, Serene W. Chen, Janet R. Kumita, Pavan K. Challa, Julius B. Kirkegaard, Samuel I. A. Cohen, Benedetta Mannini, Denise Barbut, Ellen A. A. Nollen, Cristina Cecchi, Nunilo Cremades, Tuomas P. J. Knowles, Fabrizio Chiti, Michael Zasloff, Michele Vendruscolo, Christopher M. Dobson - ACS Chemical Biology 2018 被引用: 118

  14. Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases

    著者: Ryan Limbocker, Nunilo Cremades, Roberta Cascella, Peter M. Tessier, Michele Vendruscolo, Fabrizio Chiti - Accounts of Chemical Research 2023 被引用: 45

  15. Structure–Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates

    著者: Serene W. Chen, Joseph D. Barritt, Roberta Cascella, Alessandra Bigi, Cristina Cecchi, Martina Banchelli, Angelo Gallo, James A. Jarvis, Fabrizio Chiti, Christopher M. Dobson, Giuliana Fusco, Alfonso De Simone - Journal of the American Chemical Society 2024 被引用: 43

  16. Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity

    著者: Benedetta Mannini, Estefania Mulvihill, Caterina Sgromo, Roberta Cascella, Reza Khodarahmi‬, Matteo Ramazzotti, Christopher M. Dobson, Cristina Cecchi, Fabrizio Chiti - ACS Chemical Biology 2014 被引用: 207

  17. Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies

    著者: Roberta Cascella, Claudia Capitini, Giulia Fani, Christopher M. Dobson, Cristina Cecchi, Fabrizio Chiti - Journal of Biological Chemistry 2016 被引用: 112

  18. Small molecule protein binding to correct cellular folding or stabilize the native state against misfolding and aggregation

    著者: Fabrizio Chiti, Jeffery W. Kelly - Current Opinion in Structural Biology 2022 被引用: 48

  19. Prediction of “Aggregation-prone” and “Aggregation-susceptible” Regions in Proteins Associated with Neurodegenerative Diseases

    著者: Amol Pawar, Kateri F. DuBay, Jesús Zurdo, Fabrizio Chiti, Michele Vendruscolo, Christopher M. Dobson - Journal of Molecular Biology 2005 被引用: 585

  20. Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers

    著者: Ryan Limbocker, Roxine Staats, Sean Chia, Francesco Simone Ruggeri, Benedetta Mannini, Catherine K. Xu, Michele Perni, Roberta Cascella, Alessandra Bigi, Liam R. Sasser, Natalie R. Block, Aidan K. Wright, Ryan P. Kreiser, Edward T. Custy, Georg Meisl, Silvia Errico, Johnny Habchi, Patrick Flagmeier, Tadas Kartanas, Jared E. Hollows, Lam Tung Nguyen, Kathleen LeForte, Denise Barbut, Janet R. Kumita, Cristina Cecchi, Michael Zasloff, Tuomas P. J. Knowles, Christopher M. Dobson, Fabrizio Chiti, Michele Vendruscolo - Frontiers in Neuroscience 2021 被引用: 58

  21. Protein Misfolded Oligomers: Experimental Approaches, Mechanism of Formation, and Structure-Toxicity Relationships

    著者: Francesco Bemporad, Fabrizio Chiti - Chemistry & Biology 2012 被引用: 275

  22. Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility

    著者: Alfonso De Simone, Anne Dhulesia, Gemma Soldi, Michele Vendruscolo, Shang‐Te Danny Hsu, Fabrizio Chiti, Christopher M. Dobson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 被引用: 81

  23. Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic

    著者: Ryan Limbocker, Silvia Errico, Denise Barbut, Tuomas P. J. Knowles, Michele Vendruscolo, Fabrizio Chiti, Michael Zasloff - Natural Product Reports 2021 被引用: 52

  24. Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species

    著者: Giulia Fani, Chiara Ester La Torre, Roberta Cascella, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti - Cellular and Molecular Life Sciences 2022 被引用: 44