Darrell J. Irvine
2000–2026 年に発表
- 203
- 論文数
- 34,141
- 被引用数
- 101
- h 指数
- 189
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Immunology and Microbiology27.2%
- Biochemistry, Genetics and Molecular Biology26.4%
- Medicine22.8%
- Engineering8.8%
- Materials Science6.9%
- Pharmacology, Toxicology and Pharmaceutics4.8%
- その他3.1%
トピック
- Immunotherapy and Immune Responses8.8%
- RNA Interference and Gene Delivery6%
- Nanoplatforms for cancer theranostics4.5%
- Immune Cell Function and Interaction4%
- CAR-T cell therapy research3.5%
- Nanoparticle-Based Drug Delivery3.2%
- その他70%
共著者
- Mariane B. Melo31
- William R. Schief22
- Heikyung Suh20
- Paula T. Hammond19
- Murillo Silva18
- Wuhbet Abraham18
- Kelly D. Moynihan17
- Laura Maiorino17
- Na Li16
- Christopher A. Cottrell14
- K. Dane Wittrup14
- Dennis R. Burton12
- Diane G. Carnathan12
- Sergey Menis12
- Shane Crotty12
- Erik Georgeson11
- Ivan S. Pires11
- Kristen A. Rodrigues11
- Andrew B. Ward10
- Guido Silvestri10
- J. Christopher Love10
- Sudha Kumari10
- Talar Tokatlian10
- Aereas Aung9
全論文
- Enhancing cancer immunotherapy with nanomedicine
著者: Darrell J. Irvine, Eric L. Dane - Nature reviews. Immunology 2020 被引用: 851
- STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity
著者: Eric L. Dane, Alexis Belessiotis‐Richards, Coralie M. Backlund, Jianing Wang, Kousuke Hidaka, Lauren E. Milling, Sachin Bhagchandani, Mariane B. Melo, Shengwei Wu, Na Li, Nathan D. Donahue, Kaiyuan Ni, Leyuan Ma, Masanori Okaniwa, Molly M. Stevens, Alfredo Alexander‐Katz, Darrell J. Irvine - Nature Materials 2022 被引用: 320
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
著者: Christian M. Metallo, Paulo A. Gameiro, Eric L. Bell, Katherine Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M. Jewell, Zachary Johnson, Darrell J. Irvine, Leonard Guarente, Joanne K. Kelleher, Matthew G. Vander Heiden, Othon Iliopoulos, Gregory Stephanopoulos - Nature 2011 被引用: 1,803
- Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery
著者: Li Tang, Yiran Zheng, Mariane B. Melo, Llian Mabardi, Ana P. Castaño, Yuqing Xie, Na Li, Sagar B. Kudchodkar, Hing C. Wong, Emily K. Jeng, Marcela V. Maus, Darrell J. Irvine - Nature Biotechnology 2018 被引用: 646
- Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
著者: Leyuan Ma, Alexander Hostetler, Duncan M. Morgan, Laura Maiorino, Ina Sulkaj, Charles A. Whittaker, Alexandra Neeser, Ivan S. Pires, Parisa Yousefpour, Justin M. Gregory, Kashif Qureshi, Jonathan Dye, Wuhbet Abraham, Heikyung Suh, Na Li, J. Christopher Love, Darrell J. Irvine - Cell 2023 被引用: 212
- Structure-based programming of lymph-node targeting in molecular vaccines
著者: Haipeng Liu, Kelly D. Moynihan, Yiran Zheng, Gregory L. Szeto, Adrienne V. Li, Bonnie Huang, Debra Van Egeren, Clara Park, Darrell J. Irvine - Nature 2014 被引用: 951
- Human STING is a proton channel
著者: Bingxu Liu, Rebecca J. Carlson, Ivan S. Pires, Matteo Gentili, Ellie Feng, Quentin Hellier, Marc A. Schwartz, Paul C. Blainey, Darrell J. Irvine, Nir Hacohen - Science 2023 被引用: 197
- Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor
著者: Leyuan Ma, Tanmay Dichwalkar, Jason Y.H. Chang, Benjamin Cossette, Daniel Garafola, Angela Q. Zhang, Michael Fichter, Chensu Wang, Simon Liang, Murillo Silva, Sudha Kumari, Naveen K. Mehta, Wuhbet Abraham, Nikki Thai, Na Li, K. Dane Wittrup, Darrell J. Irvine - Science 2019 被引用: 431
- Role of nanoscale antigen organization on B-cell activation probed using DNA origami
著者: Rémi Veneziano, Tyson J. Moyer, Matthew B. Stone, Eike‐Christian Wamhoff, Benjamin J. Read, Sayak Mukherjee, Tyson R. Shepherd, Jayajit Das, William R. Schief, Darrell J. Irvine, Mark Bathe - Nature Nanotechnology 2020 被引用: 442
- Multifunctional oncolytic nanoparticles deliver self-replicating IL-12 RNA to eliminate established tumors and prime systemic immunity
著者: Yingzhong Li, Zhijun Su, Weiyu Zhao, Xinfu Zhang, Noor Momin, Chengxiang Zhang, K. Dane Wittrup, Yizhou Dong, Darrell J. Irvine, Ron Weiss - Nature Cancer 2020 被引用: 235
- Long-primed germinal centres with enduring affinity maturation and clonal migration
著者: Jeong Hyun Lee, Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T. Richey, Jonathan L. Torres, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M. Cirelli, Amitinder Kaur, Carolina Allers, Marissa Fahlberg, Brooke Grasperge, Jason Dufour, Faith Schiro, Pyone P. Aye, Oleksandr Kalyuzhniy, Alessia Liguori, Diane G. Carnathan, Guido Silvestri, Xiaoying Shen, David C. Montefiori, Ronald S. Veazey, Andrew B. Ward, Lars Hangartner, Dennis R. Burton, Darrell J. Irvine, William R. Schief, Shane Crotty - Nature 2022 被引用: 192
- Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance
著者: Kimberly M. Cirelli, Diane G. Carnathan, Bartek Nogal, Jacob T. Martin, Oscar L. Rodriguez, Amit A. Upadhyay, Chiamaka A. Enemuo, Etse H. Gebru, Yury Choe, Federico Viviano, Catherine Nakao, Matthias Pauthner, Samantha Reiss, Christopher A. Cottrell, Melissa Smith, Raiza Bastidas, William Gibson, Amber Wolabaugh, Mariane B. Melo, Benjamin Cossette, Venkatesh Kumar, Nirav Patel, Talar Tokatlian, Sergey Menis, Daniel W. Kulp, Dennis R. Burton, Ben Murrell, William R. Schief, Steven E. Bosinger, Andrew B. Ward, Corey T. Watson, Guido Silvestri, Darrell J. Irvine, Shane Crotty - Cell 2019 被引用: 470
- The future of engineered immune cell therapies
著者: Darrell J. Irvine, Marcela V. Maus, David Mooney, Wilson W. Wong - Science 2022 被引用: 190
- Synthetic Nanoparticles for Vaccines and Immunotherapy
著者: Darrell J. Irvine, Melissa C. Hanson, Kavya Rakhra, Talar Tokatlian - Chemical Reviews 2015 被引用: 743
- Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
著者: Kelly D. Moynihan, Cary F. Opel, Gregory L. Szeto, Alice Tzeng, Eric Zhu, J Engreitz, Christina Williamson, Kavya Rakhra, Michael H. Zhang, Adrienne M. Rothschilds, Sudha Kumari, Ryan L. Kelly, Byron H. Kwan, Wuhbet Abraham, Kevin Hu, Naveen K. Mehta, Monique J. Kauke, Heikyung Suh, Jennifer R. Cochran, Douglas A. Lauffenburger, K. Dane Wittrup, Darrell J. Irvine - Nature Medicine 2016 被引用: 538
- Bio-inspired, bioengineered and biomimetic drug delivery carriers
著者: Jin‐Wook Yoo, Darrell J. Irvine, Dennis E. Discher, Samir Mitragotri - Nature Reviews Drug Discovery 2011 被引用: 1,221
- Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer
著者: Peter M.K. Westcott, Nathan Sacks, Jason M. Schenkel, Zackery A. Ely, Olivia Smith, Haley Hauck, Alex M. Jaeger, Daniel Zhang, Coralie M. Backlund, Mary C. Beytagh, J. J. Patten, Ryan Elbashir, George Eng, Darrell J. Irvine, Omer H. Yilmaz, Tyler Jacks - Nature Cancer 2021 被引用: 166
- Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo
著者: Yu Kato, Robert Abbott, Brian L. Freeman, Sonya Haupt, Bettina Gröschel, Murillo Silva, Sergey Menis, Darrell J. Irvine, William R. Schief, Shane Crotty - Immunity 2020 被引用: 281
- Controlling timing and location in vaccines
著者: Darrell J. Irvine, Aereas Aung, Murillo Silva - Advanced Drug Delivery Reviews 2020 被引用: 262
- Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants
著者: Sachin Bhagchandani, Jeremiah A. Johnson, Darrell J. Irvine - Advanced Drug Delivery Reviews 2021 被引用: 185
- Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
著者: Matthias T. Stephan, James J. Moon, Soong Ho Um, Anna Bershteyn, Darrell J. Irvine - Nature Medicine 2010 被引用: 738
- T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
著者: Daniela Schmid, Chun Gwon Park, Christina Hartl, Nikita Subedi, Adam N.R. Cartwright, Regina Bou-Puerto, Yiran Zheng, James Maiarana, Gordon J. Freeman, Kai W. Wucherpfennig, Darrell J. Irvine, Michael S. Goldberg - Nature Communications 2017 被引用: 441
- Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination
著者: Hok Hei Tam, Mariane B. Melo, Myungsun Kang, Jeisa M. Pelet, Vera M. Ruda, Maria Hottelet Foley, Joyce Hu, Sudha Kumari, Jordan Crampton, Alexis D. Baldeon, Rogier W. Sanders, John P. Moore, Shane Crotty, Róbert Langer, Daniel G. Anderson, Arup K. Chakraborty, Darrell J. Irvine - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 被引用: 434
- A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity
著者: Murillo Silva, Yu Kato, Mariane B. Melo, Ivy Phung, Brian L. Freeman, Zhong‐Ming Li, Kangsan Roh, Jan Willem van Wijnbergen, Hannah C. Watkins, Chiamaka A. Enemuo, Brittany L. Hartwell, Jason Y.H. Chang, Shuhao Xiao, Kristen A. Rodrigues, Kimberly M. Cirelli, Na Li, Sonya Haupt, Aereas Aung, Benjamin Cossette, Wuhbet Abraham, Swati Kataria, Raiza Bastidas, Jinal N. Bhiman, Caitlyn Linde, Nathaniel I. Bloom, Bettina Gröschel, Erik Georgeson, Nicole Phelps, Ayush Thomas, Julia Bals, Diane G. Carnathan, Daniel Lingwood, Dennis R. Burton, Galit Alter, Timothy P. Padera, Angela M. Belcher, William R. Schief, Guido Silvestri, Ruth M. Ruprecht, Shane Crotty, Darrell J. Irvine - Science Immunology 2021 被引用: 174
