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Gordon J. Freeman

1985–2025 年に発表

別表記
GORDON J. FREEMAN
325
論文数
136,930
被引用数
178
h 指数
322
i10 指数

被引用数

Gordon J. Freeman の年別被引用数1945 年: 被引用 1 件1986 年: 被引用 1 件1987 年: 被引用 5 件1988 年: 被引用 6 件1989 年: 被引用 25 件1990 年: 被引用 36 件1991 年: 被引用 38 件1992 年: 被引用 90 件1993 年: 被引用 169 件1994 年: 被引用 307 件1995 年: 被引用 357 件1996 年: 被引用 311 件1997 年: 被引用 237 件1998 年: 被引用 224 件1999 年: 被引用 271 件2000 年: 被引用 229 件2001 年: 被引用 279 件2002 年: 被引用 340 件2003 年: 被引用 460 件2004 年: 被引用 510 件2005 年: 被引用 583 件2006 年: 被引用 556 件2007 年: 被引用 767 件2008 年: 被引用 853 件2009 年: 被引用 926 件2010 年: 被引用 961 件2011 年: 被引用 896 件2012 年: 被引用 927 件2013 年: 被引用 946 件2014 年: 被引用 935 件2015 年: 被引用 1,547 件2016 年: 被引用 1,947 件2017 年: 被引用 2,203 件2018 年: 被引用 2,349 件2019 年: 被引用 5,920 件2020 年: 被引用 6,638 件2021 年: 被引用 6,855 件2022 年: 被引用 5,389 件2023 年: 被引用 4,212 件2024 年: 被引用 6,050 件2025 年: 被引用 3,001 件2026 年: 被引用 125 件1946〜1985 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 15,255 件、この内訳の 29.2%中国: 引用元論文 9,798 件、この内訳の 18.8%ドイツ: 引用元論文 2,609 件、この内訳の 5%イギリス: 引用元論文 2,528 件、この内訳の 4.9%日本: 引用元論文 2,001 件、この内訳の 3.8%フランス: 引用元論文 1,896 件、この内訳の 3.6%イタリア: 引用元論文 1,836 件、この内訳の 3.5%カナダ: 引用元論文 1,444 件、この内訳の 2.8%オーストラリア: 引用元論文 1,217 件、この内訳の 2.3%オランダ: 引用元論文 1,127 件、この内訳の 2.2%スイス: 引用元論文 1,063 件、この内訳の 2%スペイン: 引用元論文 1,021 件、この内訳の 2%
0%29.2%その他 19.9%

機関

分野

  • Medicine51.3%
  • Immunology and Microbiology26.7%
  • Biochemistry, Genetics and Molecular Biology18%
  • Engineering1.6%
  • Neuroscience1%
  • Materials Science0.3%
  • その他1.1%

トピック

  • Cancer Immunotherapy and Biomarkers11.7%
  • Immune Cell Function and Interaction8.7%
  • Immunotherapy and Immune Responses7.5%
  • CAR-T cell therapy research4.8%
  • T-cell and B-cell Immunology4.7%
  • Immune cells in cancer3.4%
  • その他59.2%

共著者

全論文

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  1. Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

    著者: Peng Jiang, Shengqing Gu, Deng Pan, Jingxin Fu, Avinash Sahu, Xihao Hu, Ziyi Li, Nicole Traugh, Xia Bu, Bo Li, Jun Liu, Gordon J. Freeman, Myles Brown, Kai W. Wucherpfennig, X. Shirley Liu - Nature Medicine 2018 被引用: 5,555

  2. PD-1 and Its Ligands in Tolerance and Immunity

    著者: Mary Keir, Manish J. Butte, Gordon J. Freeman, Arlene H. Sharpe - Annual Review of Immunology 2008 被引用: 5,342

  3. Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

    著者: Se Jin Im, Masao Hashimoto, Michael Y. Gerner, Junghwa Lee, Haydn Kissick, Matheus Carvalho Bürger, Qiang Shan, J. Scott Hale, Judong Lee, Tahseen H. Nasti, Arlene H. Sharpe, Gordon J. Freeman, Ronald N. Germain, Helder I. Nakaya, Hai‐Hui Xue, Rafi Ahmed - Nature 2016 被引用: 2,144

  4. Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

    著者: Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai, Karen Bourque, Tatyana Chernova, Hiroyuki Nishimura, Lori Fitz, Nelly Malenkovich, Taku Okazaki, Michael C. Byrne, Heidi F. Horton, Lynette A. Fouser, Laura Carter, Vincent Ling, Michael Bowman, Beatriz M. Carreno, Mary Collins, Clive R. Wood, Tasuku Honjo - The Journal of Experimental Medicine 2000 被引用: 5,235

  5. PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

    著者: Nikolaos Patsoukis, Kankana Bardhan, Pranam Chatterjee, Duygu Sari, Bianling Liu, Lauren N. Bell, Edward D. Karoly, Gordon J. Freeman, Victoria Petkova, Pankaj Seth, Lequn Li, Vassiliki A. Boussiotis - Nature Communications 2015 被引用: 1,162

  6. Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis

    著者: Kosuke Mima, Reiko Nishihara, Zhi Rong Qian, Yin Cao, Yasutaka Sukawa, Jonathan A. Nowak, Juhong Yang, Ruoxu Dou, Yohei Masugi, Mingyang Song, Aleksandar D. Kostic, Marios Giannakis, Susan Bullman, Danny A. Milner, Hideo Baba, Edward L. Giovannucci, Levi A. Garraway, Gordon J. Freeman, Glenn Dranoff, Wendy S. Garrett, Curtis Huttenhower, Matthew Meyerson, Jeffrey A. Meyerhardt, Andrew T. Chan, Charles S. Fuchs, Shuji Ogino - Gut 2015 被引用: 1,074

  7. Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

    著者: Shohei Koyama, Esra A. Akbay, Yvonne Y. Li, Grit S. Herter-Sprie, Kevin A. Buczkowski, William G. Richards, Leena Gandhi, Amanda J. Redig, Scott J. Rodig, Hajime Asahina, Robert E. Jones, Meghana Kulkarni, Mari Kuraguchi, Sangeetha Palakurthi, Peter E. Fecci, Bruce E. Johnson, Pasi A. Jänne, Jeffrey A. Engelman, Sidharta P. Gangadharan, Daniel B. Costa, Gordon J. Freeman, Raphael Bueno, F. Stephen Hodi, Glenn Dranoff, Kwok‐Kin Wong, Peter S. Hammerman - Nature Communications 2016 被引用: 1,570

  8. Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

    著者: David A. Braun, Yue Hou, Ziad Bakouny, Miriam Ficial, Miriam Sant’ Angelo, Juliet Forman, Petra Ross‐Macdonald, Ashton C. Berger, Opeyemi A. Jegede, Liudmilla Elagina, John A. Steinharter, Maxine Sun, Megan Wind‐Rotolo, Jean‐Christophe Pignon, Andrew D. Cherniack, Lee Lichtenstein, Donna Neuberg, Paul Catalano, Gordon J. Freeman, Arlene H. Sharpe, David F. McDermott, Eliezer M. Van Allen, Sabina Signoretti, Catherine J. Wu, Sachet A. Shukla, Toni K. Choueiri - Nature Medicine 2020 被引用: 1,023

  9. Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

    著者: Jinfang Zhang, Xia Bu, Haizhen Wang, Yasheng Zhu, Yan Geng, Naoe Taira Nihira, Yuyong Tan, Yanpeng Ci, Fei Wu, Xiangpeng Dai, Jianping Guo, Yuhan Huang, Caoqi Fan, Shancheng Ren, Yinghao Sun, Gordon J. Freeman, Piotr Siciński, Wenyi Wei - Nature 2017 被引用: 1,049

  10. Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

    著者: William Henry Hudson, Julia Gensheimer, Masao Hashimoto, Andreas Wieland, Rajesh M. Valanparambil, Peng Li, Jian‐Xin Lin, Bogumila T. Konieczny, Se Jin Im, Gordon J. Freeman, Warren J. Leonard, Haydn Kissick, Rafi Ahmed - Immunity 2019 被引用: 676

  11. Restoring function in exhausted CD8 T cells during chronic viral infection

    著者: Daniel L. Barber, E. John Wherry, David Masopust, Baogong Zhu, James P. Allison, Arlene H. Sharpe, Gordon J. Freeman, Rafi Ahmed - Nature 2005 被引用: 3,998

  12. Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12

    著者: Christopher Garris, Sean P. Arlauckas, Rainer H. Köhler, Marcel P. Trefny, Seth B. Garren, Cécile Piot, Camilla Engblom, Christina Pfirschke, Marie Siwicki, Jeremy Gungabeesoon, Gordon J. Freeman, Sarah Warren, SuFey Ong, Erica Browning, Chris Twitty, Robert H. Pierce, Mai H. Le, Alain P. Algazi, Adil Daud, Sara I. Pai, Alfred Zippelius, Ralph Weissleder, Mikaël J. Pittet - Immunity 2018 被引用: 937

  13. Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy

    著者: Melvyn T. Chow, Aleksandra J. Ozga, Rachel L. Servis, Dennie T. Frederick, Jennifer A. Lo, David E. Fisher, Gordon J. Freeman, Genevieve M. Boland, Andrew D. Luster - Immunity 2019 被引用: 710

  14. Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

    著者: Ilaria Elia, Jared H. Rowe, Sheila Johnson, Shakchhi Joshi, Giulia Notarangelo, Kiran Kurmi, Sarah A. Weiss, Gordon J. Freeman, Arlene H. Sharpe, Marcia C. Haigis - Cell Metabolism 2022 被引用: 341

  15. PD-L2 is a second ligand for PD-1 and inhibits T cell activation

    著者: Yvette Latchman, Clive R. Wood, Tatyana Chernova, Divya Chaudhary, Madhuri Borde, Irene Chernova, Yoshiko Iwai, Andrew J. Long, Julia A. Brown, Raquel Nunes, Edward Greenfield, Karen Bourque, Vassiliki A. Boussiotis, Laura Carter, Beatriz M. Carreno, Nelly Malenkovich, Hiroyuki Nishimura, Taku Okazaki, Tasuku Honjo, Arlene H. Sharpe, Gordon J. Freeman - Nature Immunology 2001 被引用: 2,948

  16. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

    著者: Ying Zhang, Raj K. Kurupati, Ling Liu, Xiang Zhou, Gao Zhang, Abeer Hudaihed, Flavia Filisio, Wynetta Giles‐Davis, Xiaowei Xu, Giorgos C. Karakousis, Lynn M. Schuchter, Wei Xu, Ravi K. Amaravadi, Min Xiao, Norah Sadek, Clemens Krepler, Meenhard Herlyn, Gordon J. Freeman, Joshua D. Rabinowitz, Hildegund C.J. Ertl - Cancer Cell 2017 被引用: 605

  17. PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

    著者: Stephen M. Ansell, Alexander M. Lesokhin, Ivan Borrello, Ahmad Halwani, Emma C. Scott, Martin Gutierrez, Stephen J. Schuster, Michael Millenson, Deepika Cattry, Gordon J. Freeman, Scott J. Rodig, Bjoern Chapuy, Azra H. Ligon, Lili Zhu, Joseph F. Grosso, Su Young Kim, John M. Timmerman, Margaret A. Shipp, Philippe Armand - New England Journal of Medicine 2014 被引用: 3,547

  18. The importance of exosomal PDL1 in tumour immune evasion

    著者: Dhouha Daassi, Kathleen M. Mahoney, Gordon J. Freeman - Nature reviews. Immunology 2020 被引用: 629

  19. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

    著者: Matthew M. Gubin, Xiuli Zhang, Heiko Schuster, Étienne Caron, Jeffrey P. Ward, Takuro Noguchi, Yulia Ivanova, Jasreet Hundal, Cora D. Arthur, Willem-Jan Krebber, Gwenn E. Mulder, Mireille Toebes, Matthew D. Vesely, Samuel S.K. Lam, Alan J. Korman, James P. Allison, Gordon J. Freeman, Arlene H. Sharpe, Erika L. Pearce, Ton N. Schumacher, Ruedi Aebersold, Hans-Georg Rammensee, Cornelis J.M. Melief, Elaine R. Mardis, William E. Gillanders, Maxim N. Artyomov, Robert D. Schreiber - Nature 2014 被引用: 2,006

  20. Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

    著者: Alice O. Kamphorst, Andreas Wieland, Tahseen H. Nasti, Shu Yang, Ruan Zhang, Daniel L. Barber, Bogumila T. Konieczny, Candace Daugherty, Lydia Koenig, Yu Ke, Gabriel Sica, Arlene H. Sharpe, Gordon J. Freeman, Bruce R. Blazar, Laurence A. Turka, Taofeek K. Owonikoko, Rathi N. Pillai, Suresh S. Ramalingam, Koichi Araki, Rafi Ahmed - Science 2017 被引用: 1,026

  21. PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

    著者: Masao Hashimoto, Koichi Araki, Maria A. Cardenas, Peng Li, Rohit R. Jadhav, Haydn Kissick, William Henry Hudson, Donald J. McGuire, Rebecca C. Obeng, Andreas Wieland, Judong Lee, Daniel T. McManus, James Ross, Se Jin Im, Junghwa Lee, Jian‐Xin Lin, Bin Hu, Erin E. West, Christopher D. Scharer, Gordon J. Freeman, Arlene H. Sharpe, Suresh S. Ramalingam, Alex Pellerin, Volker Teichgräber, William J. Greenleaf, Christian Klein, Jörg J. Goronzy, Pablo Umaña, Warren J. Leonard, Kendall A. Smith, Rafi Ahmed - Nature 2022 被引用: 321

  22. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

    著者: Loise M. Francisco, Victor H. Salinas, Keturah Brown, Vijay K. Vanguri, Gordon J. Freeman, Vijay K. Kuchroo, Arlene H. Sharpe - The Journal of Experimental Medicine 2009 被引用: 2,040

  23. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

    著者: Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia, Akemi Ryu, Hanspeter Waldner, Tatyana Chernova, Stephen Manning, Edward Greenfield, Anthony J. Coyle, Raymond A. Sobel, Gordon J. Freeman, Vijay K. Kuchroo - Nature 2002 被引用: 1,635

  24. LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

    著者: Wanqiang Sheng, Martin W. LaFleur, Thao H. Nguyen, Sujun Chen, Ankur Chakravarthy, Jake R. Conway, Ying Li, Hao Chen, Henry Yang, Pang‐Hung Hsu, Eliezer M. Van Allen, Gordon J. Freeman, Daniel D. De Carvalho, Housheng Hansen He, Arlene H. Sharpe, Yang Shi - Cell 2018 被引用: 692