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Christian Klein

1995–2026 年に発表

250
論文数
30,876
被引用数
87
h 指数
209
i10 指数

被引用数

Christian Klein の年別被引用数1995 年: 被引用 1 件1996 年: 被引用 2 件1997 年: 被引用 3 件1999 年: 被引用 5 件2000 年: 被引用 6 件2001 年: 被引用 14 件2002 年: 被引用 13 件2003 年: 被引用 40 件2004 年: 被引用 90 件2005 年: 被引用 145 件2006 年: 被引用 189 件2007 年: 被引用 163 件2008 年: 被引用 187 件2009 年: 被引用 200 件2010 年: 被引用 224 件2011 年: 被引用 233 件2012 年: 被引用 194 件2013 年: 被引用 235 件2014 年: 被引用 269 件2015 年: 被引用 255 件2016 年: 被引用 240 件2017 年: 被引用 275 件2018 年: 被引用 312 件2019 年: 被引用 877 件2020 年: 被引用 1,063 件2021 年: 被引用 1,366 件2022 年: 被引用 1,125 件2023 年: 被引用 977 件2024 年: 被引用 1,699 件2025 年: 被引用 988 件2026 年: 被引用 38 件1998 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 3,594 件、この内訳の 23.9%中国: 引用元論文 1,869 件、この内訳の 12.5%ドイツ: 引用元論文 1,282 件、この内訳の 8.5%イギリス: 引用元論文 967 件、この内訳の 6.4%フランス: 引用元論文 667 件、この内訳の 4.4%スイス: 引用元論文 654 件、この内訳の 4.4%イタリア: 引用元論文 625 件、この内訳の 4.2%オランダ: 引用元論文 437 件、この内訳の 2.9%オーストラリア: 引用元論文 390 件、この内訳の 2.6%スペイン: 引用元論文 390 件、この内訳の 2.6%日本: 引用元論文 370 件、この内訳の 2.5%カナダ: 引用元論文 351 件、この内訳の 2.3%
0%23.9%その他 22.8%

機関

分野

  • Medicine57.6%
  • Biochemistry, Genetics and Molecular Biology18.7%
  • Immunology and Microbiology9.6%
  • Computer Science5.1%
  • Engineering1.9%
  • Neuroscience1.3%
  • その他5.8%

トピック

  • CAR-T cell therapy research5.1%
  • Cancer Immunotherapy and Biomarkers4.9%
  • Monoclonal and Polyclonal Antibodies Research3.8%
  • Immune Cell Function and Interaction3.6%
  • Immunotherapy and Immune Responses3.6%
  • Cancer-related Molecular Pathways3.5%
  • その他75.5%

共著者

全論文

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  1. A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

    著者: Daniela S. Thommen, Viktor H. Koelzer, Petra Herzig, Andreas Roller, Marcel P. Trefny, Sarah Dimeloe, Anna Kiialainen, Jonathan Hanhart, Catherine Schill, Christoph Hess, Spasenija Savic Prince, Mark Wiese, Didier Lardinois, Ping‐Chih Ho, Christian Klein, Vaios Karanikas, Kirsten D. Mertz, Ton N. Schumacher, Alfred Zippelius - Nature Medicine 2018 被引用: 1,187

  2. In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

    著者: Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves, Daisy Carvajal, Frank Podlaski, Zoran Filipovic, Norman Kong, U. Kammlott, Christine Lukacs, Christian Klein, Nader Fotouhi, Emily A. Liu - Science 2004 被引用: 4,710

  3. The present and future of bispecific antibodies for cancer therapy

    著者: Christian Klein, Ulrich Brinkmann, Janice M. Reichert, Roland E. Kontermann - Nature Reviews Drug Discovery 2024 被引用: 421

  4. PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

    著者: Masao Hashimoto, Koichi Araki, Maria A. Cardenas, Peng Li, Rohit R. Jadhav, Haydn Kissick, William Henry Hudson, Donald J. McGuire, Rebecca C. Obeng, Andreas Wieland, Judong Lee, Daniel T. McManus, James Ross, Se Jin Im, Junghwa Lee, Jian‐Xin Lin, Bin Hu, Erin E. West, Christopher D. Scharer, Gordon J. Freeman, Arlene H. Sharpe, Suresh S. Ramalingam, Alex Pellerin, Volker Teichgräber, William J. Greenleaf, Christian Klein, Jörg J. Goronzy, Pablo Umaña, Warren J. Leonard, Kendall A. Smith, Rafi Ahmed - Nature 2022 被引用: 321

  5. PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells

    著者: Laura Codarri Deak, Valeria Nicolini, Masao Hashimoto, Maria Karagianni, Petra Schwalie, Laura Lauener, Eleni Maria Varypataki, Marine Richard, Esther Bommer, Johannes Sam, Stefanie Joller, Mario Perro, Floriana Cremasco, Leo Kunz, Emilio Yángüez, Tamara Hüsser, Ramona Schlenker, Marisa Mariani, Vinko Toševski, Sylvia Herter, Marina Bacac, Inja Waldhauer, Sara Colombetti, Xavier Guéripel, Stephan Wullschleger, Mélanie Tichet, Douglas Hanahan, Haydn Kissick, Stéphane Leclair, Anne Freimoser–Grundschober, Stefan Seeber, Volker Teichgräber, Rafi Ahmed, Christian Klein, Pablo Umaña - Nature 2022 被引用: 268

  6. Ångström-resolution fluorescence microscopy

    著者: S. Reinhardt, Luciano A. Masullo, Isabelle Pachmayr, Philipp R. Steen, Rafal Kowalewski, Alexandra S. Eklund, Sebastian Strauss, Eduard M. Unterauer, Thomas Schlichthaerle, Maximilian T. Strauss, Christian Klein, Ralf Jungmann - Nature 2023 被引用: 298

  7. Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy

    著者: Maud Mayoux, Andreas Roller, Vesna Pulko, Stefano Sammicheli, Stanford Chen, Eva Sum, Christian Jöst, Marieke F. Fransen, Regula B. Buser, Marcin Kowanetz, Karolin Rommel, Ines Matos, Sara Colombetti, Anton Belousov, Vaios Karanikas, Ferry Ossendorp, Priti S. Hegde, Daniel S. Chen, Pablo Umaña, Mario Perro, Christian Klein, Wei Xu - Science Translational Medicine 2020 被引用: 380

  8. Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases

    著者: Jörg T. Regula, Peter Lundh von Leithner, Richard Foxton, Veluchamy A. Barathi, Chui Ming Gemmy Cheung, Sai Bo Bo Tun, Yeo Sia Wey, Daiju Iwata, Miroslav Dostálek, Jörg Moelleken, Kay Stubenrauch, Everson Nogoceke, Gabriella Widmer, Pamela Strassburger, Michael Koss, Christian Klein, David T. Shima, Guido Hartmann - EMBO Molecular Medicine 2016 被引用: 359

  9. Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

    著者: Ekkehard Mössner, Peter Brünker, Samuel Moser, Ursula Püntener, Carla Schmidt, Sylvia Herter, Roger Grau, Christian Gerdes, Adam Nopora, Erwin van Puijenbroek, Claudia Ferrara, Peter Sondermann, Christiane Jäger, Pamela Strein, Georg Fertig, Thomas Friess, Christine Schüll, Sabine Bauer, Joseph Dal Porto, Christopher Del Nagro, Karim Dabbagh, Martin J.S. Dyer, Sibrand Poppema, Christian Klein, Pablo Umaña - Blood 2010 被引用: 957

  10. CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies

    著者: Marina Bacac, Sara Colombetti, Sylvia Herter, Johannes Sam, Mario Perro, Stanford Chen, Roberta Bianchi, Marine Richard, Anne Schoenle, Valeria Nicolini, Sarah Diggelmann, Florian Limani, Ramona Schlenker, Tamara Hüsser, W. Richter, Katharine Bray‐French, Heather Hinton, Anna Maria Giusti, Anne Freimoser–Grundschober, Laurent Larivière, Christiane Neumann, Christian Klein, Pablo Umaña - Clinical Cancer Research 2018 被引用: 238

  11. Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

    著者: Tilman Schlothauer, Sylvia Herter, Claudia Ferrara, Sandra Grau-Richards, Virginie Steinhart, Christian Spick, Manfred Kubbies, Christian Klein, Pablo Umaña, Ekkehard Mössner - Protein Engineering Design and Selection 2016 被引用: 419

  12. Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

    著者: Mélanie Tichet, Stephan Wullschleger, Agnieszka Chryplewicz, Nadine Fournier, Rachel Marcone, Annamaria Kauzlaric, Krisztián Homicskó, Laura Codarri Deak, Pablo Umaña, Christian Klein, Douglas Hanahan - Immunity 2023 被引用: 128

  13. Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker

    著者: Flavio Solca, G. Dahl, Andreas Zoephel, Gerd Bader, Michael P. Sanderson, Christian Klein, Oliver Kraemer, Frank Himmelsbach, Eric Haaksma, Guenther R. Adolf - Journal of Pharmacology and Experimental Therapeutics 2012 被引用: 867

  14. Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies

    著者: Wolfgang Schäfer, Jörg T. Regula, Monika Bähner, Jürgen Schanzer, Rebecca Croasdale, Harald Dürr, Christian Gassner, Guy Georges, Hubert Kettenberger, Sabine Imhof-Jung, Manfred Schwaiger, Kay Stubenrauch, Claudio Sustmann, Markus Thomas, Werner Scheuer, Christian Klein - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 被引用: 479

  15. A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors

    著者: Marina Bacac, Tanja Fauti, Johannes Sam, Sara Colombetti, Tina Weinzierl, Djamila Ouaret, Walter F. Bodmer, Steffi Lehmann, Thomas Höfer, Ralf J. Hosse, Ekkehard Moessner, Oliver Ast, Peter Bruenker, Sandra Grau-Richards, Teilo Schaller, Annette Seidl, Christian Gerdes, Mario Perro, Valeria Nicolini, Nathalie Steinhoff, Sherri Dudal, Sebastian Neumann, Thomas von Hirschheydt, Christiane Jaeger, Jose Saro, Vaios Karanikas, Christian Klein, Pablo Umaña - Clinical Cancer Research 2016 被引用: 355

  16. Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines

    著者: Christian Klein, Inja Waldhauer, Valeria Nicolini, Anne Freimoser–Grundschober, Tapan K. Nayak, Daniëlle J. Vugts, Claire Dunn, Marije Bolijn, Jörg Benz, M. Stihle, Sabine M. Lang, Michaele Roemmele, Thomas Höfer, Erwin van Puijenbroek, David Wittig, Samuel Moser, Oliver Ast, Peter Brünker, Ingo H. Gorr, Sebastian Neumann, Maria Cristina De Vera Mudry, Heather Hinton, Flavio Crameri, Jose Saro, Stefan Evers, Christian Gerdes, Marina Bacac, Guus A.M.S. van Dongen, Ekkehard Moessner, Pablo Umaña - OncoImmunology 2017 被引用: 283

  17. The Influence of Firm Size on the ESG Score: Corporate Sustainability Ratings Under Review

    著者: Samuel Drempetic, Christian Klein, Bernhard Zwergel - Journal of Business Ethics 2019 被引用: 1,446

  18. Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy

    著者: Christina Claus, Claudia Ferrara, Wei Xu, Johannes Sam, Sabine M. Lang, Franziska Uhlenbrock, R. Albrecht, Sylvia Herter, Ramona Schlenker, Tamara Hüsser, Sarah Diggelmann, John Challier, Ekkehard Mössner, Ralf J. Hosse, Thomas Höfer, Peter Brünker, Catherine Joseph, Jörg Benz, Philippe Ringler, Henning Stahlberg, Matthias E. Lauer, Mario Perro, Stanford Chen, Christine Küttel, Preethi Latha Bhavani Mohan, Valeria Nicolini, Martina Birk, Amandine Ongaro, Christophe Prince, Reto Gianotti, Gregory O. Dugan, Christopher T. Whitlow, Kiran Kumar Solingapuram Sai, David L. Caudell, Armando G. Burgos-Rodríguez, J. Mark Cline, Michael Hettich, Maurizio Ceppi, Anna Maria Giusti, Flavio Crameri, Wouter H. P. Driessen, Peter N. Morcos, Anne Freimoser–Grundschober, Victor Levitsky, Maria Amann, Sandra Grau-Richards, Thomas von Hirschheydt, Stella Tournaviti, Michael Mølhøj, Tanja Fauti, Viola Heinzelmann‐Schwarz, Volker Teichgräber, Sara Colombetti, Marina Bacac, Alfred Zippelius, Christian Klein, Pablo Umaña - Science Translational Medicine 2019 被引用: 266

  19. Sirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma

    著者: Edward K. Geissler, Andreas A. Schnitzbauer, C. Zülke, P. Lamby, Andrea Proneth, Christophe Duvoux, Patrizia Burra, Karl‐Walter Jauch, Markus Rentsch, Tom M. Ganten, Jan Schmidt, Utz Settmacher, Michael Heise, G. Rossi, Umberto Cillo, Norman M. Kneteman, René Adam, Bart van Hoek, Philippe Bachellier, Philippe Wolf, Lionel Rostaing, Wolf O. Bechstein, Magnus Rizell, James J. Powell, Ernest Hidalgo, Jean Gugenheim, Heiner Wolters, Jens Brockmann, André Roy, Ingrid Mutzbauer, Angela Schlitt, Susanne Beckebaum, Christian Graeb, Silvio Nadalin, Umberto Valente, Víctor Sánchez Turrión, Neville V. Jamieson, Tim Scholz, M. Colledan, Fred Fändrich, Thomas Becker, Gunnar Söderdahl, Olivier Chazouillères, Heikki Mäkisalo, Georges‐Philippe Pageaux, Rudolf Steininger, Thomas Soliman, Koert P. de Jong, Jacques Pirenne, Raimund Margreiter, Johann Pratschke, Antonio D. Pinna, Johann Hauss, Stefan Schreiber, Simone I. Strasser, Jürgen Klempnauer, Roberto Troisi, Sherrie Bhoori, Jan Lerut, Itxarone Bilbao, Christian Klein, Alfred Königsrainer, Darius F. Mirza, Gerd Otto, Vincenzo Mazzaferro, P. Neuhaus, Hans J. Schlitt - Transplantation 2015 被引用: 417

  20. Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors

    著者: Daniela S. Thommen, Jens Schreiner, Philipp Müller, Petra Herzig, Andreas Roller, Anton Belousov, Pablo Umaña, Pavel Pisa, Christian Klein, Marina Bacac, Ozana S. Fischer, Wolfgang Moersig, Spasenija Savic Prince, Victor Levitsky, Vaios Karanikas, Didier Lardinois, Alfred Zippelius - Cancer Immunology Research 2015 被引用: 381

  21. Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy

    著者: Inja Waldhauer, Valeria Gonzalez‐Nicolini, Anne Freimoser–Grundschober, Tapan K. Nayak, Linda Fahrni, Ralf J. Hosse, Danny Gerrits, E.J. Geven, Johannes Sam, Sabine M. Lang, Esther Bommer, Virginie Steinhart, Elisabeth Husar, Sara Colombetti, Erwin van Puijenbroek, Markus Neubauer, J. Mark Cline, Pradeep Garg, Gregory O. Dugan, Federica Cavallo, Gonzalo Acuña, Jehad Charo, Volker Teichgräber, Stefan Evers, Otto C. Boerman, Marina Bacac, Ekkehard Moessner, Pablo Umaña, Christian Klein - mAbs 2021 被引用: 118

  22. The emerging landscape of novel 4-1BB (CD137) agonistic drugs for cancer immunotherapy

    著者: Christina Claus, Claudia Ferrara, Christian Klein - mAbs 2023 被引用: 101

  23. Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment

    著者: Anja Seckinger, Jose Antonio Delgado, Samuel Moser, Laura Moreno, Brigitte Neuber, Anna Luise Grab, Susanne Lipp, Juana Merino, Felipe Prósper, Martina Emde, Camille Delon, Melanie Latzko, Reto Gianotti, Remo Lüoend, Ramona Murr, Ralf J. Hosse, Lydia Jasmin Harnisch, Marina Bacac, Tanja Fauti, Christian Klein, Aintzane Zabaleta, Jens Hillengaß, Elisabetta Ada Cavalcanti‐Adam, Anthony D. Ho, Michael Hundemer, Jesús F. San Miguel, K. Strein, Pablo Umaña, Dirk Hose, Bruno Paiva, Minh Diem Vu - Cancer Cell 2017 被引用: 312

  24. Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties

    著者: Christian Klein, Alfred Lammens, Wolfgang Schäfer, Guy Georges, Manfred Schwaiger, Ekkehard Mössner, Karl‐Peter Hopfner, Pablo Umaña, Gerhard Niederfellner - mAbs 2013 被引用: 386