Jeffrey A. Engelman
1997–2025 年に発表
- 181
- 論文数
- 84,399
- 被引用数
- 131
- h 指数
- 179
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine53.2%
- Biochemistry, Genetics and Molecular Biology37.4%
- Immunology and Microbiology2.9%
- Computer Science2%
- Engineering1.2%
- Chemistry0.7%
- その他2.6%
トピック
- Lung Cancer Treatments and Mutations7.5%
- Cancer Genomics and Diagnostics3.7%
- Cancer Immunotherapy and Biomarkers3.5%
- PI3K/AKT/mTOR signaling in cancer3.3%
- Lung Cancer Research Studies3.1%
- HER2/EGFR in Cancer Research2.1%
- その他76.8%
共著者
- Alice T. Shaw37
- Lecia V. Sequist35
- A. John Iafrate30
- Pasi A. Jänne30
- Mari Mino–Kenudson28
- Justin F. Gainor25
- Cyril H. Benes23
- Michael P. Lisanti21
- Aaron N. Hata17
- Anthony C. Faber16
- Youngchul Song16
- Dora Dias‐Santagata15
- Kwok‐Kin Wong15
- Ryan B. Corcoran15
- Ryohei Katayama15
- Elizabeth L. Lockerman14
- Hiromichi Ebi14
- Lewis C. Cantley14
- Matthew J. Niederst14
- Eugene Lifshits13
- Jeffrey Settleman13
- Carlotta Costa12
- Luc Friboulet12
- Rebecca S. Heist12
全論文
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
著者: Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv, Shubhroz Gill, Ossia M. Eichhoff, Brinton Seashore‐Ludlow, Samuel D. Kaffenberger, John K. Eaton, Kenichi Shimada, Andrew J. Aguirre, Srinivas R. Viswanathan, Shrikanta Chattopadhyay, Pablo Tamayo, Wan Seok Yang, Matthew G. Rees, Sixun Chen, Žarko Bošković, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen‐Yi Tseng, Elisabeth Roider, Dong Gao, James M. Cleary, Brian M. Wolpin, Jill P. Mesirov, Daniel A. Haber, Jeffrey A. Engelman, Jesse S. Boehm, Joanne Kotz, Cindy Hon, Yu Chen, William C. Hahn, Mitchell P. Levesque, John G. Doench, Michael E. Berens, Alykhan F. Shamji, Paul A. Clemons, Brent R. Stockwell, Stuart L. Schreiber - Nature 2017 被引用: 2,059
- Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
著者: Shohei Koyama, Esra A. Akbay, Yvonne Y. Li, Grit S. Herter-Sprie, Kevin A. Buczkowski, William G. Richards, Leena Gandhi, Amanda J. Redig, Scott J. Rodig, Hajime Asahina, Robert E. Jones, Meghana Kulkarni, Mari Kuraguchi, Sangeetha Palakurthi, Peter E. Fecci, Bruce E. Johnson, Pasi A. Jänne, Jeffrey A. Engelman, Sidharta P. Gangadharan, Daniel B. Costa, Gordon J. Freeman, Raphael Bueno, F. Stephen Hodi, Glenn Dranoff, Kwok‐Kin Wong, Peter S. Hammerman - Nature Communications 2016 被引用: 1,570
- Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
著者: Lecia V. Sequist, Belinda A. Waltman, Dora Dias‐Santagata, Subba R. Digumarthy, Alexa B. Turke, Panos Fidias, Kristin Bergethon, Alice T. Shaw, Scott Gettinger, Arjola K. Cosper, Sara Akhavanfard, Rebecca S. Heist, Jennifer S. Temel, James G. Christensen, John C. Wain, Thomas J. Lynch, Kathy Vernovsky, Eugene J. Mark, Michael Lanuti, A. John Iafrate, Mari Mino–Kenudson, Jeffrey A. Engelman - Science Translational Medicine 2011 被引用: 3,556
- The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
著者: Jeffrey A. Engelman, Ji Luo, Lewis C. Cantley - Nature Reviews Genetics 2006 被引用: 3,310
- MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
著者: Jeffrey A. Engelman, Kreshnik Zejnullahu, Tetsuya Mitsudomi, Youngchul Song, Courtney Hyland, Joon Oh Park, Neal I. Lindeman, Christopher-Michael Gale, Xiao‐Jun Zhao, James G. Christensen, Takayuki Kosaka, Alison J. Holmes, Andrew M. Rogers, Federico Cappuzzo, Tony Mok, Charles Lee, Bruce E. Johnson, Lewis C. Cantley, Pasi A. Jänne - Science 2007 被引用: 4,485
- Systematic identification of genomic markers of drug sensitivity in cancer cells
著者: Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn, Chris Greenman, Anahita Dastur, King Wai Lau, Patricia Greninger, I. Richard Thompson, Xi Luo, Jorge Soares, Qingsong Liu, Francesco Iorio, Didier Surdez, Li Chen, Randy Milano, Graham R. Bignell, Ah Ting Tam, Helen Davies, Jesse A. Stevenson, Syd Barthorpe, Stephen Lutz, Fiona Kogera, Karl Lawrence, Anne McLaren-Douglas, Xeni Mitropoulos, Tatiana Mironenko, Helen Thi, Laura Richardson, Wenjun Zhou, Frances Jewitt, Tinghu Zhang, Patrick O’Brien, Jessica L. Boisvert, Stacey Price, Wooyoung Hur, Wanjuan Yang, Xianming Deng, Adam P. Butler, Hwan Geun Choi, Jae Won Chang, José Baselga, Ivan Stamenkovic, Jeffrey A. Engelman, Sreenath V. Sharma, Olivier Delattre, Julio Sáez-Rodríguez, Nathanael S. Gray, Jeffrey Settleman, P. Andrew Futreal, Daniel A. Haber, Michael R. Stratton, Sridhar Ramaswamy, Ultan McDermott, Cyril H. Benes - Nature 2012 被引用: 2,601
- Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition
著者: Aaron N. Hata, Matthew J. Niederst, Hannah L. Archibald, María Gomez‐Caraballo, Faria M. Siddiqui, Hillary E. Mulvey, Yosef E. Maruvka, Fei Ji, Hyo-Eun Carrie Bhang, Viveksagar Krishnamurthy Radhakrishna, Giulia Siravegna, Haichuan Hu, Sana Raoof, Elizabeth L. Lockerman, Anuj Kalsy, Dana Lee, Celina L Keating, David A. Ruddy, Leah J. Damon, Adam Crystal, Carlotta Costa, Zofia Piotrowska, Alberto Bardelli, A. John Iafrate, Ruslan I. Sadreyev, Frank Stegmeier, Gad Getz, Lecia V. Sequist, Anthony C. Faber, Jeffrey A. Engelman - Nature Medicine 2016 被引用: 999
- Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms
著者: Haichuan Hu, Zofia Piotrowska, Patricia J. Hare, Huidong Chen, Hillary E. Mulvey, Aislinn Mayfield, Sundus Noeen, Krystina E. Kattermann, Max Greenberg, August Williams, Amanda K. Riley, Jarad Wilson, Yingqing Mao, Ruo‐Pan Huang, Mandeep K. Banwait, Jeffrey Ho, Giovanna Stein Crowther, Lida P. Hariri, Rebecca S. Heist, David P. Kodack, Luca Pinello, Alice T. Shaw, Mari Mino–Kenudson, Aaron N. Hata, Lecia V. Sequist, Cyril H. Benes, Matthew J. Niederst, Jeffrey A. Engelman - Cancer Cell 2021 被引用: 261
- Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin
著者: Matthew G. Oser, Matthew J. Niederst, Lecia V. Sequist, Jeffrey A. Engelman - The Lancet Oncology 2015 被引用: 949
- EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non–Small Cell Lung Cancer: A Retrospective Analysis
著者: Justin F. Gainor, Alice T. Shaw, Lecia V. Sequist, Xiujun Fu, Christopher G. Azzoli, Zofia Piotrowska, Tiffany G. Huynh, Ling Zhao, Linnea Fulton, Katherine R. Schultz, Emily Howe, Anna F. Farago, Ryan J. Sullivan, James R. Stone, Subba R. Digumarthy, Teresa Morán, Aaron N. Hata, Yukako Yagi, Beow Y. Yeap, Jeffrey A. Engelman, Mari Mino–Kenudson - Clinical Cancer Research 2016 被引用: 1,241
- Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia
著者: Elena J. Orlando, Xia Han, Catherine Tribouley, Patricia A. Wood, Rebecca Leary, Markus Riester, John E. Levine, Muna Qayed, Stephan A. Grupp, Michael Boyer, Barbara De Moerloose, Eneida R. Nemecek, Henrique Bittencourt, Hidefumi Hiramatsu, Jochen Buechner, Stella M. Davies, Michael R. Verneris, Kevin T. Nguyen, Jennifer L. Brogdon, Hans Bitter, Michael Morrissey, Piotr Pierog, Serafino Pantano, Jeffrey A. Engelman, Wendy Winckler - Nature Medicine 2018 被引用: 567
- Prospects for combining targeted and conventional cancer therapy with immunotherapy
著者: Philip J. Gotwals, Scott B. Cameron, Daniela Cipolletta, Viviana Cremasco, Adam Crystal, Becker Hewes, Britta Mueller, Sonia Quaratino, Catherine Sabatos-Peyton, Lilli Petruzzelli, Jeffrey A. Engelman, Glenn Dranoff - Nature reviews. Cancer 2017 被引用: 965
- Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy
著者: Simone Bonazzi, Eva d’Hennezel, Rohan E. J. Beckwith, Lei Xu, Aleem Fazal, Anna Magracheva, Radha Ramesh, Artiom Cernijenko, Brandon Antonakos, Hyo‐eun C. Bhang, Roxana García Caro, Jennifer Cobb, Elizabeth Ornelas, Xiaolei Ma, Charles Wartchow, Matthew C. Clifton, Ry R. Forseth, Bethany Hughes Fortnam, Hongbo Lu, Alfredo Csibi, Jennifer Tullai, Seth Carbonneau, Noel M. Thomsen, Jay F. Larrow, B. Chie-Leon, Dominik Hainzl, Yi Gu, Darlene Lu, Matthew J. Meyer, Dylan C. Alexander, Jacqueline Kinyamu-Akunda, Catherine Sabatos-Peyton, Natalie A. Dales, Frédéric J. Zécri, Rishi K. Jain, Janine Shulok, Yinchuan Wang, Karin Briner, Jeffery A. Porter, John A. Tallarico, Jeffrey A. Engelman, Glenn Dranoff, James E. Bradner, Michael Visser, Jonathan M. Solomon - Cell chemical biology 2023 被引用: 156
- Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK -Rearranged Lung Cancer
著者: Justin F. Gainor, Leila Dardaei, Satoshi Yoda, Luc Friboulet, Ignaty Leshchiner, Ryohei Katayama, Ibiayi Dagogo‐Jack, Shirish M. Gadgeel, Katherine R. Schultz, Manrose Singh, Emily Chin, Melissa Parks, Dana Lee, Richard H. DiCecca, Elizabeth L. Lockerman, Tiffany G. Huynh, Jennifer Logan, Lauren L. Ritterhouse, Long P. Le, Ashok Muniappan, Subba R. Digumarthy, Colleen L. Channick, Colleen Keyes, Gad Getz, Dora Dias‐Santagata, Rebecca S. Heist, Jochen K. Lennerz, Lecia V. Sequist, Cyril H. Benes, A. John Iafrate, Mari Mino–Kenudson, Jeffrey A. Engelman, Alice T. Shaw - Cancer Discovery 2016 被引用: 1,144
- EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF -Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib
著者: Ryan B. Corcoran, Hiromichi Ebi, Alexa B. Turke, Erin M. Coffee, Michiya Nishino, Alexandria P. Cogdill, Ronald D. Brown, Patricia Della Pelle, Dora Dias‐Santagata, Kenneth E. Hung, Keith T. Flaherty, Adriano Piris, Jennifer A. Wargo, Jeffrey Settleman, Mari Mino–Kenudson, Jeffrey A. Engelman - Cancer Discovery 2012 被引用: 1,027
- Targeting PI3K signalling in cancer: opportunities, challenges and limitations
著者: Jeffrey A. Engelman - Nature reviews. Cancer 2009 被引用: 2,455
- ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics
著者: Carlos L. Arteaga, Jeffrey A. Engelman - Cancer Cell 2014 被引用: 1,070
- Anchored multiplex PCR for targeted next-generation sequencing
著者: Zongli Zheng, Matthew Liebers, Boryana Zhelyazkova, Yi Cao, Divya Panditi, Kerry D. Lynch, Juxiang Chen, Hayley Robinson, Hyo Sup Shim, Juliann Chmielecki, William Pao, Jeffrey A. Engelman, A. John Iafrate, Long P. Le - Nature Medicine 2014 被引用: 917
- The present and future of PI3K inhibitors for cancer therapy
著者: Pau Castel, Eneda Toska, Jeffrey A. Engelman, Maurizio Scaltriti - Nature Cancer 2021 被引用: 223
- Therapy-induced APOBEC3A drives evolution of persistent cancer cells
著者: Hideko Isozaki, Ramin Sakhtemani, Ammal Abbasi, Naveed Nikpour, Marcello Stanzione, Sunwoo Oh, Adam Langenbucher, Susanna Monroe, Wenjia Su, Heidie Frisco Cabanos, Faria M. Siddiqui, Nicole Phan, Pégah Jalili, Daria Timonina, Samantha Bilton, María Gomez‐Caraballo, Hannah L. Archibald, Varuna Nangia, Kristin Dionne, Amanda K. Riley, Matthew A. Lawlor, Mandeep K. Banwait, Rosemary Cobb, Lee Zou, Nicholas J. Dyson, Christopher J. Ott, Cyril H. Benes, Gad Getz, Chang S. Chan, Alice T. Shaw, Justin F. Gainor, Jessica J. Lin, Lecia V. Sequist, Zofia Piotrowska, Beow Y. Yeap, Jeffrey A. Engelman, Jake June-Koo Lee, Yosef E. Maruvka, Rémi Buisson, Michael S. Lawrence, Aaron N. Hata - Nature 2023 被引用: 145
- The Allelic Context of the C797S Mutation Acquired upon Treatment with Third-Generation EGFR Inhibitors Impacts Sensitivity to Subsequent Treatment Strategies
著者: Matthew J. Niederst, Haichuan Hu, Hillary E. Mulvey, Elizabeth L. Lockerman, Angel R. Garcia, Zofia Piotrowska, Lecia V. Sequist, Jeffrey A. Engelman - Clinical Cancer Research 2015 被引用: 548
- Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors
著者: Diana Miao, Claire A. Margolis, Natalie I. Vokes, David Liu, Amaro Taylor‐Weiner, Stephanie A. Wankowicz, Dennis O. Adeegbe, Daniel Keliher, Bastian Schilling, Adam Tracy, Michael P. Manos, Nicole G. Chau, Glenn J. Hanna, Paz Polak, Scott J. Rodig, Sabina Signoretti, Lynette M. Sholl, Jeffrey A. Engelman, Gad Getz, Pasi A. Jänne, Robert I. Haddad, Toni K. Choueiri, David A. Barbie, Rizwan Haq, Mark M. Awad, Dirk Schadendorf, F. Stephen Hodi, Joaquim Bellmunt, Kwok‐Kin Wong, Peter S. Hammerman, Eliezer M. Van Allen - Nature Genetics 2018 被引用: 696
- ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers
著者: Kristin Bergethon, Alice T. Shaw, Sai‐Hong Ignatius Ou, Ryohei Katayama, Christine M. Lovly, Nerina T. McDonald, Pierre P. Massion, Christina T. Siwak-Tapp, Adriana González, Rong Fang, Eugene J. Mark, Julie M. Batten, Haiquan Chen, Keith D. Wilner, Eunice L. Kwak, Jeffrey W. Clark, David P. Carbone, Hongbin Ji, Jeffrey A. Engelman, Mari Mino–Kenudson, William Pao, A. John Iafrate - Journal of Clinical Oncology 2012 被引用: 1,557
- PTEN Loss Mediates Clinical Cross-Resistance to CDK4/6 and PI3Kα Inhibitors in Breast Cancer
著者: Carlotta Costa, Ye Wang, Amy Ly, Yasuyuki Hosono, Ellen Murchie, Charlotte S. Walmsley, Tiffany G. Huynh, Christopher Healy, Rachel Peterson, Shogo Yanase, Charles T. Jakubik, Laura E. Henderson, Leah J. Damon, Daria Timonina, Ioannis Sanidas, Christopher J. Pinto, Mari Mino–Kenudson, James R. Stone, Nicholas J. Dyson, Leif W. Ellisen, Aditya Bardia, Hiromichi Ebi, Cyril H. Benes, Jeffrey A. Engelman, Dejan Juric - Cancer Discovery 2019 被引用: 269
