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Taku Okazaki

1995–2022 年に発表

50
論文数
27,568
被引用数
45
h 指数
50
i10 指数

被引用数

Taku Okazaki の年別被引用数1994 年: 被引用 2 件1995 年: 被引用 7 件1996 年: 被引用 26 件1997 年: 被引用 71 件1998 年: 被引用 56 件1999 年: 被引用 38 件2000 年: 被引用 41 件2001 年: 被引用 67 件2002 年: 被引用 111 件2003 年: 被引用 190 件2004 年: 被引用 175 件2005 年: 被引用 173 件2006 年: 被引用 191 件2007 年: 被引用 206 件2008 年: 被引用 212 件2009 年: 被引用 209 件2010 年: 被引用 213 件2011 年: 被引用 180 件2012 年: 被引用 234 件2013 年: 被引用 268 件2014 年: 被引用 279 件2015 年: 被引用 451 件2016 年: 被引用 559 件2017 年: 被引用 574 件2018 年: 被引用 469 件2019 年: 被引用 1,299 件2020 年: 被引用 1,320 件2021 年: 被引用 1,274 件2022 年: 被引用 959 件2023 年: 被引用 678 件2024 年: 被引用 1,079 件2025 年: 被引用 462 件2026 年: 被引用 14 件

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 3,257 件、この内訳の 29.1%中国: 引用元論文 1,799 件、この内訳の 16.1%日本: 引用元論文 766 件、この内訳の 6.8%ドイツ: 引用元論文 560 件、この内訳の 5%イギリス: 引用元論文 487 件、この内訳の 4.4%イタリア: 引用元論文 421 件、この内訳の 3.8%フランス: 引用元論文 388 件、この内訳の 3.5%カナダ: 引用元論文 297 件、この内訳の 2.7%オーストラリア: 引用元論文 262 件、この内訳の 2.3%オランダ: 引用元論文 230 件、この内訳の 2.1%スイス: 引用元論文 217 件、この内訳の 1.9%スペイン: 引用元論文 211 件、この内訳の 1.9%
0%29.1%その他 20.4%

機関

分野

  • Medicine60.7%
  • Immunology and Microbiology21.9%
  • Biochemistry, Genetics and Molecular Biology11.2%
  • Neuroscience4.1%
  • Engineering1.1%
  • Materials Science0.2%
  • その他0.8%

トピック

  • Cancer Immunotherapy and Biomarkers17.8%
  • Immune Cell Function and Interaction9.9%
  • Immunotherapy and Immune Responses9%
  • CAR-T cell therapy research6.3%
  • T-cell and B-cell Immunology3.7%
  • Immune cells in cancer3.1%
  • その他50.2%

共著者

全論文

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  1. Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

    著者: Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai, Karen Bourque, Tatyana Chernova, Hiroyuki Nishimura, Lori Fitz, Nelly Malenkovich, Taku Okazaki, Michael C. Byrne, Heidi F. Horton, Lynette A. Fouser, Laura Carter, Vincent Ling, Michael Bowman, Beatriz M. Carreno, Mary Collins, Clive R. Wood, Tasuku Honjo - The Journal of Experimental Medicine 2000 被引用: 5,235

  2. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

    著者: Yoshiko Iwai, Masayoshi Ishida, Yoshimasa Tanaka, Taku Okazaki, Tasuku Honjo, Nagahiro Minato - National Academy of Sciences, Proceedings of the National Academy of Sciences 2002 被引用: 3,191

  3. PD-L2 is a second ligand for PD-1 and inhibits T cell activation

    著者: Yvette Latchman, Clive R. Wood, Tatyana Chernova, Divya Chaudhary, Madhuri Borde, Irene Chernova, Yoshiko Iwai, Andrew J. Long, Julia A. Brown, Raquel Nunes, Edward Greenfield, Karen Bourque, Vassiliki A. Boussiotis, Laura Carter, Beatriz M. Carreno, Nelly Malenkovich, Hiroyuki Nishimura, Taku Okazaki, Tasuku Honjo, Arlene H. Sharpe, Gordon J. Freeman - Nature Immunology 2001 被引用: 2,948

  4. LAG-3: from molecular functions to clinical applications

    著者: Takumi Maruhashi, Daisuke Sugiura, Il‐mi Okazaki, Taku Okazaki - Journal for ImmunoTherapy of Cancer 2020 被引用: 462

  5. Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice

    著者: Hiroyuki Nishimura, Taku Okazaki, Yoshimasa Tanaka, Kazuki Nakatani, Masatake Hara, Akira Matsumori, Shigetake Sasayama, Akira Mizoguchi, Hiroshi Hiai, Nagahiro Minato, Tasuku Honjo - Science 2001 被引用: 1,864

  6. PD-1 and PD-1 ligands: from discovery to clinical application

    著者: Taku Okazaki, T Honjo - International Immunology 2007 被引用: 1,289

  7. Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity

    著者: Takumi Maruhashi, Daisuke Sugiura, Il‐mi Okazaki, Kenji Shimizu, Takeo K. Maeda, Jun Ikubo, Harunori Yoshikawa, Katsumi Maenaka, Naozumi Ishimaru, Hidetaka Kosako, Tatsuya Takemoto, Taku Okazaki - Immunity 2022 被引用: 200

  8. Restriction of PD-1 function by cis -PD-L1/CD80 interactions is required for optimal T cell responses

    著者: Daisuke Sugiura, Takumi Maruhashi, Il‐mi Okazaki, Kenji Shimizu, Takeo K. Maeda, Tatsuya Takemoto, Taku Okazaki - Science 2019 被引用: 377

  9. LAG-3 inhibits the activation of CD4+ T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII

    著者: Takumi Maruhashi, Il‐mi Okazaki, Daisuke Sugiura, Suzuka Takahashi, Takeo K. Maeda, Kenji Shimizu, Taku Okazaki - Nature Immunology 2018 被引用: 276

  10. A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

    著者: Taku Okazaki, Shunsuke Chikuma, Yoshiko Iwai, Sidonia Fagarasan, Tasuku Honjo - Nature Immunology 2013 被引用: 915

  11. Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice

    著者: Taku Okazaki, Yoshimasa Tanaka, Ryosuke Nishio, Tamotsu Mitsuiye, Akira Mizoguchi, Jian Wang, Masayoshi Ishida, Hiroshi Hiai, Akira Matsumori, Nagahiro Minato, Tasuku Honjo - Nature Medicine 2003 被引用: 683

  12. The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors

    著者: David Yin-wei Lin, Yoshimasa Tanaka, Masashi Iwasaki, Apostolos G. Gittis, Hua-Poo Su, Bunzo Mikami, Taku Okazaki, Tasuku Honjo, Nagahiro Minato, David N. Garboczi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 被引用: 457

  13. PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

    著者: Taku Okazaki, Akito Maeda, Hiroyuki Nishimura, Tomohiro Kurosaki, Tasuku Honjo - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 被引用: 840

  14. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer

    著者: Junzo Hamanishi, Masaki Mandai, Masashi Iwasaki, Taku Okazaki, Yoshimasa Tanaka, Ken Yamaguchi, Toshihiro Higuchi, Haruhiko Yagi, Kenji Takakura, Nagahiro Minato, Tasuku Honjo, Shingo Fujii - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 被引用: 1,372

  15. PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

    著者: Taku Okazaki, Il‐mi Okazaki, Jian Wang, Daisuke Sugiura, Fumio Nakaki, Taku Yoshida, Yu Kato, Sidonia Fagarasan, Masamichi Muramatsu, Tomoo Eto, Kyoji Hioki, Tasuku Honjo - The Journal of Experimental Medicine 2011 被引用: 332

  16. PD-1 deficiency results in the development of fatal myocarditis in MRL mice

    著者: Jian Wang, Il‐mi Okazaki, Taku Yoshida, Shunsuke Chikuma, Yu Kato, Fumio Nakaki, Hiroshi Hiai, Tasuku Honjo, Taku Okazaki - International Immunology 2010 被引用: 271

  17. IFN-α Directly Promotes Programmed Cell Death-1 Transcription and Limits the Duration of T Cell-Mediated Immunity

    著者: Seigo Terawaki, Shunsuke Chikuma, Shiro Shibayama, Tamon Hayashi, Takao Yoshida, Taku Okazaki, Tasuku Honjo - The Journal of Immunology 2011 被引用: 337

  18. PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity

    著者: Daisuke Sugiura, Il‐mi Okazaki, Takeo K. Maeda, Takumi Maruhashi, Kenji Shimizu, Rieko Arakaki, Tatsuya Takemoto, Naozumi Ishimaru, Taku Okazaki - Nature Immunology 2022 被引用: 108

  19. Atypical motifs in the cytoplasmic region of the inhibitory immune co-receptor LAG-3 inhibit T cell activation

    著者: Takeo K. Maeda, Daisuke Sugiura, Il‐mi Okazaki, Takumi Maruhashi, Taku Okazaki - Journal of Biological Chemistry 2019 被引用: 106

  20. The PD-1–PD-L pathway in immunological tolerance

    著者: Taku Okazaki, Tasuku Honjo - Trends in Immunology 2006 被引用: 716

  21. PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation

    著者: Reina Mizuno, Daisuke Sugiura, Kenji Shimizu, Takumi Maruhashi, Mizuki Watada, Il‐mi Okazaki, Taku Okazaki - Frontiers in Immunology 2019 被引用: 173

  22. PD-1-Mediated Suppression of IL-2 Production Induces CD8+ T Cell Anergy In Vivo

    著者: Shunsuke Chikuma, Seigo Terawaki, Tamon Hayashi, Ryusuke Nabeshima, Takao Yoshida, Shiro Shibayama, Taku Okazaki, Tasuku Honjo - The Journal of Immunology 2009 被引用: 242

  23. Establishment of NOD- Pdcd1 -/- mice as an efficient animal model of type I diabetes

    著者: Jian Wang, Taku Yoshida, Fumio Nakaki, Hiroshi Hiai, Taku Okazaki, Tasuku Honjo - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 被引用: 429

  24. PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation

    著者: Kenji Shimizu, Daisuke Sugiura, Il‐mi Okazaki, Takumi Maruhashi, Yujiro Takegami, Chaoyang Cheng, Soichi Ozaki, Taku Okazaki - Molecular Cell 2020 被引用: 63