David B. Ascher
1992–2026 年に発表
- 139
- 論文数
- 19,118
- 被引用数
- 58
- h 指数
- 119
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology38.5%
- Medicine27.9%
- Computer Science17.1%
- Chemistry4.8%
- Neuroscience2.4%
- Agricultural and Biological Sciences2.3%
- その他7%
トピック
- Computational Drug Discovery Methods9.6%
- Protein Structure and Dynamics4.9%
- Synthesis and biological activity3.1%
- RNA and protein synthesis mechanisms2.6%
- Machine Learning in Bioinformatics2%
- Tuberculosis Research and Epidemiology1.8%
- その他76%
共著者
- Douglas E. V. Pires68
- Carlos H. M. Rodrigues32
- Tom L. Blundell22
- Stephanie Portelli18
- Yoochan Myung18
- Alex G. C. de Sá16
- Michael Silk9
- Raghad Al-Jarf7
- Michael W. Parker6
- Thanh Nguyen6
- Yunzhuo Zhou6
- Joicymara S. Xavier5
- Malancha Karmakar5
- Thanh-Binh Nguyen5
- João P. L. Velloso4
- Kathryn E. Holt4
- Pâmela M. Rezende4
- A. Pacitto3
- Angelique R. Ormsby3
- Annalisa Santucci3
- Arun Prasad Pandurangan3
- Azadeh Alavi3
- Bernardo Ochoa‐Montaño3
- Bruna Moreira da Silva3
全論文
- pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
著者: Douglas E. V. Pires, Tom L. Blundell, David B. Ascher - Journal of Medicinal Chemistry 2015 被引用: 5,389
- A structural biology community assessment of AlphaFold2 applications
著者: Mehmet Akdel, Douglas E. V. Pires, Eduard Porta‐Pardo, Jürgen Jänes, Arthur O. Zalevsky, Bálint Mészáros, Patrick Bryant, Lydia L. Good, Roman A. Laskowski, Gabriele Pozzati, Aditi Shenoy, Wensi Zhu, Petras J. Kundrotas, Victoria Ruiz‐Serra, Carlos H. M. Rodrigues, Alistair S. Dunham, David F. Burke, Neera Borkakoti, Sameer Velankar, Adam Frost, J. Basquin, Kresten Lindorff‐Larsen, Alex Bateman, Andrey V. Kajava, Alfonso Valencia, Sergey Ovchinnikov, Janani Durairaj, David B. Ascher, Janet M. Thornton, Norman E. Davey, Amelie Stein, Arne Elofsson, Tristan I. Croll, Pedro Beltrão - Nature Structural & Molecular Biology 2022 被引用: 718
- DynaMut2: Assessing changes in stability and flexibility upon single and multiple point missense mutations
著者: Carlos H. M. Rodrigues, Douglas E. V. Pires, David B. Ascher - Protein Science 2020 被引用: 657
- mCSM: predicting the effects of mutations in proteins using graph-based signatures
著者: Douglas E. V. Pires, David B. Ascher, Tom L. Blundell - Bioinformatics, Bioinform. 2013 被引用: 1,108
- DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach
著者: Douglas E. V. Pires, David B. Ascher, Tom L. Blundell - Nucleic Acids Research, Nucleic Acids Res. 2014 被引用: 962
- DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
著者: Carlos H. M. Rodrigues, Douglas E. V. Pires, David B. Ascher - Nucleic Acids Research, Nucleic Acids Res. 2018 被引用: 1,139
- Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction
著者: Yoochan Myung, Alex G. C. de Sá, David B. Ascher - Nucleic Acids Research 2024 被引用: 263
- DDMut: predicting effects of mutations on protein stability using deep learning
著者: Yunzhuo Zhou, Qisheng Pan, Douglas E. V. Pires, Carlos H. M. Rodrigues, David B. Ascher - Nucleic Acids Research, Nucleic Acids Res. 2023 被引用: 257
- Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures
著者: Harry Jubb, Alícia P. Higueruelo, Bernardo Ochoa‐Montaño, William R. Pitt, David B. Ascher, Tom L. Blundell - Journal of Molecular Biology 2016 被引用: 521
- mCSM-PPI2: predicting the effects of mutations on protein-protein interactions
著者: Carlos H. M. Rodrigues, Yoochan Myung, Douglas E. V. Pires, David B. Ascher - Nucleic Acids Research, Nucleic Acids Res. 2019 被引用: 385
- Sequence grammar underlying the unfolding and phase separation of globular proteins
著者: Kiersten M. Ruff, Yoon Hee Choi, Dezerae Cox, Angelique R. Ormsby, Yoochan Myung, David B. Ascher, Sheena E. Radford, Rohit V. Pappu, Danny M. Hatters - Molecular Cell 2022 被引用: 109
- CSM-Toxin: A Web-Server for Predicting Protein Toxicity
著者: Vladimir Morozov, Carlos H. M. Rodrigues, David B. Ascher - Pharmaceutics 2023 被引用: 106
- ThermoMutDB: a thermodynamic database for missense mutations
著者: Joicymara S. Xavier, Thanh-Binh Nguyen, Malancha Karmarkar, Stephanie Portelli, Pâmela M. Rezende, João P. L. Velloso, David B. Ascher, Douglas E. V. Pires - Nucleic Acids Research, Nucleic Acids Res. 2020 被引用: 104
- mmCSM-PPI: predicting the effects of multiple point mutations on protein-protein interactions
著者: Carlos H. M. Rodrigues, Douglas E. V. Pires, David B. Ascher - Nucleic Acids Research, Nucleic Acids Res. 2021 被引用: 88
- epitope3D: a machine learning method for conformational B-cell epitope prediction
著者: Bruna Moreira da Silva, Yoochan Myung, David B. Ascher, Douglas E. V. Pires - Briefings in Bioinformatics, Briefings Bioinform. 2021 被引用: 87
- CSM-AB: graph-based antibody-antigen binding affinity prediction and docking scoring function
著者: Yoochan Myung, Douglas E. V. Pires, David B. Ascher - Bioinformatics, Bioinform. 2021 被引用: 75
- SDM: a server for predicting effects of mutations on protein stability
著者: Arun Prasad Pandurangan, Bernardo Ochoa-Montaño, David B. Ascher, Tom L. Blundell - Nucleic Acids Research, Nucleic Acids Res. 2017 被引用: 535
- Prediction and Optimization of Pharmacokinetic and Toxicity Properties of the Ligand
著者: Douglas E. V. Pires, Lisa M. Kaminskas, David B. Ascher - Methods in molecular biology 2018 被引用: 128
- toxCSM: comprehensive prediction of small molecule toxicity profiles
著者: Alex G. C. de Sá, Yangyang Long, Stephanie Portelli, Douglas E. V. Pires, David B. Ascher - Briefings in Bioinformatics, Briefings Bioinform. 2022 被引用: 53
- Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD
著者: Katrina Andrews, David B. Ascher, Douglas E. V. Pires, Daniel R. Barnes, Lindsey Vialard, Ruth Casey, Nicola Bradshaw, Julian Adlard, Simon Aylwin, Paul Brennan, Carole Brewer, Trevor Cole, Jackie Cook, Rosemarie Davidson, Alan Donaldson, Alan Fryer, Lynn Greenhalgh, Shirley V. Hodgson, Richard Irving, Fiona Lalloo, Michelle McConachie, Vivienne McConnell, Patrick J. Morrison, Victoria Murday, Soo‐Mi Park, Helen Simpson, Katie Snape, Susan E. Stewart, Susan Tomkins, Yvonne Wallis, Louise Izatt, David Goudie, Robert S. Lindsay, Colin Perry, Emma R. Woodward, Antonis C. Antoniou, Eamonn R. Maher - Journal of Medical Genetics 2018 被引用: 251
- Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation
著者: Joshua L. Traynelis, Michael Silk, Quanli Wang, Samuel F. Berkovic, Liping Liu, David B. Ascher, David J. Balding, Slavé Petrovski - Genome Research 2017 被引用: 186
- DDMut-PPI: predicting effects of mutations on protein–protein interactions using graph-based deep learning
著者: Yunzhuo Zhou, Yoochan Myung, Carlos H. M. Rodrigues, David B. Ascher - Nucleic Acids Research 2024 被引用: 53
- cardioToxCSM: A Web Server for Predicting Cardiotoxicity of Small Molecules
著者: Saba Iftkhar, Alex G. C. de Sá, João P. L. Velloso, Raghad Al-Jarf, Douglas E. V. Pires, David B. Ascher - Journal of Chemical Information and Modeling, J. Chem. Inf. Model. 2022 被引用: 53
- A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
著者: Joanne M. Hildebrand, Maria Kauppi, Ian J. Majewski, Zikou Liu, Allison Cox, Sanae Miyake, Emma J. Petrie, Michael Silk, Zhixiu Li, Maria C. Tanzer, Gabriela Brumatti, Samuel N. Young, Cathrine Hall, Sarah E. Garnish, Jason Corbin, Michael D. Stutz, Ladina Di Rago, Pradnya Gangatirkar, Emma C. Josefsson, Kristin A. Rigbye, Holly Anderton, James Rickard, Anne Tripaydonis, Julie M. Sheridan, Thomas Scerri, Victoria E. Jackson, Peter E. Czabotar, Jian‐Guo Zhang, Leila N. Varghese, Cody C. Allison, Marc Pellegrini, Gillian M. Tannahill, Esme C. Hatchell, Tracy A. Willson, Dina Stockwell, Carolyn A. de Graaf, Janelle E. Collinge, Adrienne A. Hilton, Natasha Silke, Sukhdeep K. Spall, Diep Chau, Vicki Athanasopoulos, Donald Metcalf, Ronald M. Laxer, Alexander G. Bassuk, Benjamin W. Darbro, Maria A. Fiatarone Singh, Nicole Vlahovich, David Hughes, Maria Kozlovskaia, David B. Ascher, Klaus Warnatz, Nils Venhoff, Jens Thiel, Christine Biben, Stefan Blum, John D. Reveille, Michael S. Hildebrand, Carola G. Vinuesa, Pamela McCombe, Matthew A. Brown, Benjamin T. Kile, Catriona McLean, Melanie Bahlo, Seth L. Masters, Hiroyasu Nakano, Polly J. Ferguson, James M. Murphy, Warren S. Alexander, John Silke - Nature Communications 2020 被引用: 95
