Peter E. Czabotar
2003–2025 年に発表
- 85
- 論文数
- 25,339
- 被引用数
- 58
- h 指数
- 84
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology44.5%
- Medicine36.8%
- Immunology and Microbiology8.6%
- Computer Science1.7%
- Neuroscience1.5%
- Agricultural and Biological Sciences1.4%
- その他5.5%
トピック
- Cell death mechanisms and regulation7.5%
- Inflammasome and immune disorders3.7%
- Autophagy in Disease and Therapy3.5%
- Ferroptosis and cancer prognosis3.4%
- interferon and immune responses2.1%
- Mitochondrial Function and Pathology2.1%
- その他77.7%
共著者
- James M. Murphy22
- Guillaume Lessène20
- Richard W. Birkinshaw20
- David C.S. Huang18
- Peter M. Colman18
- Brian J. Smith14
- Grant Dewson14
- Samuel N. Young14
- Jarrod J. Sandow13
- Ahmad Z. Wardak12
- Joanne M. Hildebrand11
- W. Douglas Fairlie11
- Andrew I. Webb10
- Erinna F. Lee10
- Emma J. Petrie9
- Mark F. van Delft9
- Katherine A. Davies8
- Kym N. Lowes8
- Ruth M. Kluck8
- Sarah E. Garnish8
- Cheree Fitzgibbon7
- Isabelle S. Lucet7
- Jerry M. Adams7
- John Silke7
全論文
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
著者: Lorenzo Galluzzi, Ilio Vitale, Stuart A. Aaronson, John Abrams, Dieter Adam, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Margherita Annicchiarico‐Petruzzelli, Alexey V. Antonov, Eli Arama, Eric H. Baehrecke, Nickolai A. Barlev, Nicolás G. Bazán, Francesca Bernassola, Mathieu J.M. Bertrand, Katiuscia Bianchi, Mikhail V. Blagosklonny, Klas Blomgren, Christoph Borner, Patricia Boya, Catherine Brenner, Michelangelo Campanella, Eleonora Candi, Didac Carmona‐Gutiérrez, Francesco Cecconi, Francis Ka-Ming Chan, Navdeep S. Chandel, Emily H. Cheng, Jerry E. Chipuk, John A. Cidlowski, Aaron Ciechanover, Gerald M. Cohen, Marcus Conrad, Juan R. Cubillos‐Ruiz, Peter E. Czabotar, Vincenzo D’Angiolella, Ted M. Dawson, Valina L. Dawson, Vincenzo De Laurenzi, Ruggero De Maria, Klaus‐Michael Debatin, Ralph J. DeBerardinis, Mohanish Deshmukh, Nicola Di Daniele, Francesco Di Virgilio, Vishva M. Dixit, Scott J. Dixon, Colin S. Duckett, Brian David Dynlacht, Wafik S. El‐Deiry, John W. Elrod, Gian María Fimia, Simone Fulda, Ana J. García‐Sáez, Abhishek D. Garg, Carmen Garrido, Evripidis Gavathiotis, Pierre Golstein, Eyal Gottlieb, Douglas R. Green, Lloyd A. Greene, Hinrich Gronemeyer, Atan Gross, György Hajnóczky, J. Marie Hardwick, Isaac S. Harris, Michael O. Hengartner, Claudio Hetz, Hidenori Ichijo, Marja Jäättelä, Bertrand Joseph, Philipp J. Jost, Philippe Juin, William J. Kaiser, Michael Karin, Thomas Kaufmann, Oliver Kepp, Adi Kimchi, Richard N. Kitsis, Daniel J. Klionsky, Richard A. Knight, Sharad Kumar, Sam W. Lee, John J. Lemasters, Beth Levine, Andreas Linkermann, Stuart A. Lipton, Richard A. Lockshin, Carlos López-Otı́n, Scott W. Lowe, Tom Luedde, Enrico Lugli, Marion MacFarlane, Frank Madeo, Michal Malewicz, Walter Malorni, Gwenola Manic ほか 69 名 - Cell Death and Differentiation 2018 被引用: 6,498
- Mechanisms of BCL-2 family proteins in mitochondrial apoptosis
著者: Peter E. Czabotar, Ana J. García‐Sáez - Nature Reviews Molecular Cell Biology 2023 被引用: 601
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
著者: Peter E. Czabotar, Guillaume Lessène, Andreas Strasser, Jerry M. Adams - Nature Reviews Molecular Cell Biology 2013 被引用: 3,192
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
著者: James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand, Isabelle S. Lucet, Jian‐Guo Zhang, Silvia Álvarez-Díaz, Rowena S. Lewis, Najoua Lalaoui, Donald Metcalf, Andrew I. Webb, Samuel N. Young, Leila N. Varghese, Gillian M. Tannahill, Esme C. Hatchell, Ian J. Majewski, Toru Okamoto, Renwick C. J. Dobson, Douglas J. Hilton, Jeffrey J. Babon, Nicos A. Nicola, Andreas Strasser, John Silke, Warren S. Alexander - Immunity 2013 被引用: 1,214
- Apoptotic cell death in disease—Current understanding of the NCCD 2023
著者: Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A. Aaronson, John Abrams, Dieter Adam, Massimiliano Agostini, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Rami I. Aqeilan, Eli Arama, Eric H. Baehrecke, Siddharth Balachandran, Daniele Bano, Nickolai A. Barlev, Jiří Bártek, Nicolás G. Bazán, Christoph Becker, Francesca Bernassola, Mathieu J.M. Bertrand, Marco E. Bianchi, Mikhail V. Blagosklonny, J. Magarian Blander, Giovanni Blandino, Klas Blomgren, Christoph Borner, Carl D. Bortner, Pierluigi Bove, Patricia Boya, Catherine Brenner, Petr Brož, Thomas Brunner, Rune Busk Damgaard, George A. Calin, Michelangelo Campanella, Eleonora Candi, Michele Carbone, Didac Carmona‐Gutiérrez, Francesco Cecconi, Francis Ka-Ming Chan, Guoqiang Chen, Quan Chen, Youhai H. Chen, Emily H. Cheng, Jerry E. Chipuk, John A. Cidlowski, Aaron Ciechanover, Gennaro Ciliberto, Marcus Conrad, Juan R. Cubillos‐Ruiz, Peter E. Czabotar, Vincenzo D’Angiolella, Mads Daugaard, Ted M. Dawson, Valina L. Dawson, Ruggero De Maria, Bart De Strooper, Klaus‐Michael Debatin, Ralph J. DeBerardinis, Alexei Degterev, Giannino Del Sal, Mohanish Deshmukh, Francesco Di Virgilio, Marc Diederich, Scott J. Dixon, Brian David Dynlacht, Wafik S. El‐Deiry, John W. Elrod, Kurt Engeland, Gian María Fimia, Claudia Galassi, Carlo Ganini, Ana J. García‐Sáez, Abhishek D. Garg, Carmen Garrido, Evripidis Gavathiotis, Motti Gerlic, Sourav Ghosh, Douglas R. Green, Lloyd A. Greene, Hinrich Gronemeyer, Georg Häcker, György Hajnóczky, J. Marie Hardwick, Ygal Haupt, Sudan He, David M. Heery, Michael O. Hengartner, Claudio Hetz, David A. Hildeman, Hidenori Ichijo, Satoshi Inoue, Marja Jäättelä, Ana Janic, Bertrand Joseph, Philipp J. Jost, Thirumala‐Devi Kanneganti ほか 128 名 - Cell Death and Differentiation 2023 被引用: 351
- The manipulation of apoptosis for cancer therapy using BH3-mimetic drugs
著者: Sarah T. Diepstraten, Mary Ann Anderson, Peter E. Czabotar, Guillaume Lessène, Andreas Strasser, Gemma L. Kelly - Nature reviews. Cancer 2021 被引用: 354
- Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
著者: Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet, Samuel N. Young, Sukhdeep K. Spall, Pooja Sharma, Catia L. Pierotti, Jean‐Marc Garnier, Renwick C. J. Dobson, Andrew I. Webb, Anne Tripaydonis, Jeffrey J. Babon, Mark D. Mulcair, M.J. Scanlon, Warren S. Alexander, Andrew F. Wilks, Peter E. Czabotar, Guillaume Lessène, James M. Murphy, John Silke - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 被引用: 596
- Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
著者: Theresa Klemm, Gregor Ebert, Dale J. Calleja, Cody C. Allison, Lachlan W. Richardson, Jonathan P. Bernardini, Bernadine G.C. Lu, Nathan W. Kuchel, Christoph Grohmann, Y. Shibata, Zhong Yan Gan, James P. Cooney, Marcel Doerflinger, Amanda E. Au, T. Blackmore, Gerbrand J. van der Heden van Noort, Paul P. Geurink, Huib Ovaa, Janet Newman, Alan Riboldi‐Tunnicliffe, Peter E. Czabotar, Jeffrey P. Mitchell, Rebecca Feltham, Bernhard C. Lechtenberg, Kym N. Lowes, Grant Dewson, Marc Pellegrini, Guillaume Lessène, David Komander - The EMBO Journal 2020 被引用: 494
- Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia
著者: Piers Blombery, Mary Ann Anderson, Jianan Gong, Rachel Thijssen, Richard W. Birkinshaw, Ella R. Thompson, Charis E. Teh, Tamia Nguyen, Zhen Xu, Christoffer Flensburg, Thomas E. Lew, Ian J. Majewski, Daniel H.D. Gray, David Westerman, Constantine S. Tam, John F. Seymour, Peter E. Czabotar, David C.S. Huang, Andrew W. Roberts - Cancer Discovery 2018 被引用: 426
- BAX, BAK, and BOK: A Coming of Age for the BCL-2 Family Effector Proteins
著者: Tudor Moldoveanu, Peter E. Czabotar - Cold Spring Harbor Perspectives in Biology 2019 被引用: 183
- Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
著者: Richard W. Birkinshaw, Jianan Gong, Cindy S. Luo, Daisy Lio, Christine White, Mary Ann Anderson, Piers Blombery, Guillaume Lessène, Ian J. Majewski, Rachel Thijssen, Andrew W. Roberts, David C.S. Huang, Peter M. Colman, Peter E. Czabotar - Nature Communications 2019 被引用: 244
- Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
著者: Yanxiang Meng, Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Christopher R. Horne, Cindy S. Luo, Jean‐Marc Garnier, Lung‐Yu Liang, Angus D. Cowan, André L. Samson, Guillaume Lessène, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy - Nature Communications 2021 被引用: 103
- Multiple BCL2 mutations cooccurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax
著者: Piers Blombery, Ella R. Thompson, Tamia Nguyen, Richard W. Birkinshaw, Jianan Gong, Xiangting Chen, Michelle McBean, Rachel Thijssen, Thomas Conway, Mary Ann Anderson, John F. Seymour, David Westerman, Peter E. Czabotar, David C.S. Huang, Andrew W. Roberts - Blood 2020 被引用: 158
- Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
著者: Peter E. Czabotar, Dana Westphal, Grant Dewson, Stephen Ma, Colin Hockings, W. Douglas Fairlie, Erinna F. Lee, Shenggen Yao, A.Y. Robin, Brian J. Smith, David C.S. Huang, Ruth M. Kluck, Jerry M. Adams, Peter M. Colman - Cell 2013 被引用: 580
- Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
著者: Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Z. Wardak, Lung‐Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessène, John Silke, Peter E. Czabotar, Andrew I. Webb, James M. Murphy - Nature Communications 2018 被引用: 193
- The regulation of necroptosis by post-translational modifications
著者: Yanxiang Meng, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy - Cell Death and Differentiation 2021 被引用: 120
- Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
著者: Sarah E. Garnish, Yanxiang Meng, Akiko Koide, Jarrod J. Sandow, Eric Denbaum, Annette V. Jacobsen, Wayland Yeung, André L. Samson, Christopher R. Horne, Cheree Fitzgibbon, Samuel N. Young, Phoebe P. C. Smith, Andrew I. Webb, Emma J. Petrie, Joanne M. Hildebrand, Natarajan Kannan, Peter E. Czabotar, Shohei Koide, James M. Murphy - Nature Communications 2021 被引用: 107
- The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments
著者: Jian‐Guo Zhang, Peter E. Czabotar, Antonia N. Policheni, Irina Caminschi, Soo San Wan, Susie Kitsoulis, Kirsteen M. Tullett, A.Y. Robin, Rajini Brammananth, Mark F. van Delft, Jinhua Lu, Lorraine A. O’Reilly, Emma C. Josefsson, Benjamin T. Kile, Wei Jin Chin, Justine D. Mintern, Maya A. Olshina, Wilson Wong, Jake Baum, Mark D. Wright, David C.S. Huang, Narla Mohandas, Ross L. Coppel, Peter M. Colman, Nicos A. Nicola, Ken Shortman, Mireille H. Lahoud - Immunity 2012 被引用: 332
- The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
著者: Mark F. van Delft, Andrew H. Wei, Kylie D. Mason, Cassandra J. Vandenberg, Lin Chen, Peter E. Czabotar, Simon N. Willis, Clare L. Scott, Catherine L. Day, Suzanne Cory, Jerry M. Adams, Andrew W. Roberts, David C.S. Huang - Cancer Cell 2006 被引用: 1,220
- Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK
著者: Francine Ke, Hannah Vanyai, Angus D. Cowan, Alex R. D. Delbridge, Lachlan Whitehead, Stephanie Grabow, Peter E. Czabotar, Anne K. Voss, Andreas Strasser - Cell 2018 被引用: 208
- Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy
著者: Jonathan P. Bernardini, Jason M. Brouwer, Iris K. L. Tan, Jarrod J. Sandow, Shuai Huang, Che A. Stafford, Aleksandra Bankovacki, Christopher D. Riffkin, Ahmad Z. Wardak, Peter E. Czabotar, Michael Lazarou, Grant Dewson - The EMBO Journal 2018 被引用: 114
- Discovery of a Potent and Selective BCL-X L Inhibitor with in Vivo Activity
著者: Zhi‐Fu Tao, Lisa Hasvold, Le Wang, Xilu Wang, Andrew M. Petros, Chang H. Park, Erwin R. Boghaert, Nathaniel D. Catron, Jun Chen, Peter M. Colman, Peter E. Czabotar, Kurt Deshayes, Wayne J. Fairbrother, John A. Flygare, S.G. Hymowitz, Sha Jin, Russell A. Judge, Michael F. T. Koehler, Peter Kovar, Guillaume Lessène, Michael J. Mitten, Chudi Ndubaku, Paul Nimmer, Hans E. Purkey, Anatol Oleksijew, Darren C. Phillips, Brad E. Sleebs, Brian J. Smith, Morey L. Smith, Stephen K. Tahir, Keith G. Watson, Xiao Yu, John Xue, Haichao Zhang, Kerry Zobel, Saul H. Rosenberg, Chris Tse, Joel D. Leverson, Steven W. Elmore, Andrew J. Souers - ACS Medicinal Chemistry Letters 2014 被引用: 331
- From (Tool)Bench to Bedside: The Potential of Necroptosis Inhibitors
著者: Christopher R. Gardner, Katherine A. Davies, Ying Zhang, Martin Brzozowski, Peter E. Czabotar, James M. Murphy, Guillaume Lessène - Journal of Medicinal Chemistry 2023 被引用: 53
- The BCL-2 family of proteins and mitochondrial outer membrane permeabilisation
著者: Richard W. Birkinshaw, Peter E. Czabotar - Seminars in Cell and Developmental Biology 2017 被引用: 224
