Huib Ovaa
2002–2025 年に発表
- 120
- 論文数
- 19,557
- 被引用数
- 79
- h 指数
- 119
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology51.3%
- Medicine26%
- Immunology and Microbiology9.9%
- Chemistry5%
- Computer Science2.9%
- Neuroscience1.8%
- その他3.1%
トピック
- Ubiquitin and proteasome pathways11%
- Peptidase Inhibition and Analysis3%
- SARS-CoV-2 and COVID-19 Research2.9%
- Protein Degradation and Inhibitors2.7%
- Autophagy in Disease and Therapy2.6%
- interferon and immune responses2.5%
- その他75.3%
共著者
- Paul P. Geurink24
- Jacques Neefjes14
- Celia R. Berkers13
- Monique P. C. Mulder13
- David Komander12
- Gerbrand J. van der Heden van Noort12
- Hidde L. Ploegh11
- Ayşegül Sapmaz10
- Farid El Oualid10
- Benedikt M. Kessler8
- Reggy Ekkebus8
- Cami Talavera Ormeño7
- Titia K. Sixma7
- Alfred C.O. Vertegaal6
- Annemieke de Jong6
- Brenda A. Schulman6
- Harald M. H. G. Albers6
- Herman S. Overkleeft6
- Katharina F. Witting6
- Boris Rodenko5
- Ilana Berlin5
- Jin Gan5
- Klaus‐Peter Knobeloch5
- Martijn Verdoes5
全論文
- Proteome-wide identification of ubiquitin interactions using UbIA-MS
著者: Xiao-Fei Zhang, Arne H. Smits, Gabriëlle B. A. van Tilburg, Huib Ovaa, Wolfgang Huber, Michiel Vermeulen - Nature Protocols 2018 被引用: 911
- Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
著者: Dong Hyuk Shin, Rukmini Mukherjee, Diana Grewe, Denisa Bojková, Kheewoong Baek, Anshu Bhattacharya, Laura Schulz, Marek Widera, Ahmad Reza Mehdipour, Georg Tascher, Paul P. Geurink, Alexander Wilhelm, Gerbrand J. van der Heden van Noort, Huib Ovaa, Stefan Müller, Klaus‐Peter Knobeloch, Krishnaraj Rajalingam, Brenda A. Schulman, Jindřich Činátl, Gerhard Hummer, Sandra Ciesek, Ivan Đikić - Nature 2020 被引用: 1,247
- Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
著者: Theresa Klemm, Gregor Ebert, Dale J. Calleja, Cody C. Allison, Lachlan W. Richardson, Jonathan P. Bernardini, Bernadine G.C. Lu, Nathan W. Kuchel, Christoph Grohmann, Y. Shibata, Zhong Yan Gan, James P. Cooney, Marcel Doerflinger, Amanda E. Au, T. Blackmore, Gerbrand J. van der Heden van Noort, Paul P. Geurink, Huib Ovaa, Janet Newman, Alan Riboldi‐Tunnicliffe, Peter E. Czabotar, Jeffrey P. Mitchell, Rebecca Feltham, Bernhard C. Lechtenberg, Kym N. Lowes, Grant Dewson, Marc Pellegrini, Guillaume Lessène, David Komander - The EMBO Journal 2020 被引用: 494
- Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening
著者: Efrat Resnick, A.R. Bradley, Jinrui Gan, A. Douangamath, T. Krojer, Ritika Sethi, Paul P. Geurink, A. Aimon, Gabriel Amitai, Dom Bellini, James M. Bennett, M. Fairhead, Oleg Fedorov, Ronen Gabizon, Jin Gan, Jingxu Guo, A.N. Plotnikov, Nava Reznik, G.F. Ruda, L. Diaz Saez, Verena M. Straub, Tamás Szommer, Srikannathasan Velupillai, Daniel Zaidman, Yanling Zhang, Alun R. Coker, Christopher G. Dowson, Haim Barr, Chu Wang, K. Huber, Paul E. Brennan, Huib Ovaa, F. von Delft, Nir London - Journal of the American Chemical Society 2019 被引用: 342
- OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis
著者: Tycho E.T. Mevissen, Manuela K. Hospenthal, Paul P. Geurink, P.R. Elliott, Masato Akutsu, N. Arnaudo, Reggy Ekkebus, Yogesh Kulathu, Tobias Wauer, Farid El Oualid, Stefan M.V. Freund, Huib Ovaa, David Komander - Cell 2013 被引用: 642
- Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
著者: Rik van der Kant, Vanessa F. Langness, Cheryl Herrera, Daniel A. Williams, Lauren Fong, Yves Leestemaker, Evelyne Steenvoorden, Kevin D. Rynearson, Jos F. Brouwers, J. Bernd Helms, Huib Ovaa, Martin Giera, Steven L. Wagner, Anne G. Bang, Lawrence S.B. Goldstein - Cell stem cell 2019 被引用: 373
- Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly
著者: Daniel Horn‐Ghetko, David T. Krist, J. Rajan Prabu, Kheewoong Baek, Monique P. C. Mulder, Maren Klügel, Daniel C. Scott, Huib Ovaa, Gary Kleiger, Brenda A. Schulman - Nature 2021 被引用: 199
- USP8 promotes cancer progression and extracellular vesicle‐mediated CD8+ T cell exhaustion by deubiquitinating the TGF‐β receptor TβRII
著者: Feng Xie, Xiaoxue Zhou, Heyu Li, Peng Su, Sijia Liu, Ran Li, Jing Zou, Wei Xiang, Chen Pan, Zhengkui Zhang, Min Zheng, Zhuang Liu, Xuli Meng, Huib Ovaa, Peter ten Dijke, Fangfang Zhou, Long Zhang - The EMBO Journal 2022 被引用: 89
- Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin
著者: Baoxu Pang, Xiaohang Qiao, Lennert Janssen, Arno Velds, Tom A. Groothuis, Ron Kerkhoven, Marja Nieuwland, Huib Ovaa, Sven Rottenberg, Olaf van Tellingen, Jeroen J. W. M. Janssen, Peter C. Huijgens, Wilbert Zwart, Jacques Neefjes - Nature Communications 2013 被引用: 431
- Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity
著者: Jorg van Loosdregt, Veerle Fleskens, Juan Fu, Arjan B. Brenkman, Cornelis P. J. Bekker, Cornelieke Pals, Jenny Meerding, Celia R. Berkers, Joseph Barbi, Andrea Gröne, Alice J.A.M. Sijts, Madelon M. Maurice, Eric Kalkhoven, Berent J. Prakken, Huib Ovaa, Fan Pan, Dietmar M. Zaiss, Paul J. Coffer - Immunity 2013 被引用: 311
- Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase
著者: Alex C. Faesen, Annette M.G. Dirac, Anitha Shanmugham, Huib Ovaa, Anastassis Perrakis, Titia K. Sixma - Molecular Cell 2011 被引用: 252
- On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases
著者: Reggy Ekkebus, Sander I. van Kasteren, Yogesh Kulathu, Arjen Scholten, Ilana Berlin, Paul P. Geurink, Annemieke de Jong, Soenita S. Goerdayal, Jacques Neefjes, Albert J. R. Heck, David Komander, Huib Ovaa - Journal of the American Chemical Society 2013 被引用: 360
- An Interaction Landscape of Ubiquitin Signaling
著者: Xiaofei Zhang, Arne H. Smits, Gabriëlle B. A. van Tilburg, Pascal W.T.C. Jansen, Matthew Makowski, Huib Ovaa, Michiel Vermeulen - Molecular Cell 2017 被引用: 163
- Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
著者: Daniel C. Scott, David Y. Rhee, David M. Duda, Ian R. Kelsall, Jennifer L. Olszewski, João A. Paulo, Annemieke de Jong, Huib Ovaa, Arno F. Alpi, J. Wade Harper, Brenda A. Schulman - Cell 2016 被引用: 233
- Two Novel Ubiquitin-fold Modifier 1 (Ufm1)-specific Proteases, UfSP1 and UfSP2
著者: Sung Hwan Kang, Gi Ryang Kim, Minu Seong, Sung Hee Baek, Jae Hong Seol, Ok Sun Bang, Huib Ovaa, K. Tatsumi, Masaaki Komatsu, Keiji Tanaka, Chin Ha Chung - Journal of Biological Chemistry 2006 被引用: 193
- BAP1/ASXL1 recruitment and activation for H2A deubiquitination
著者: Danny D. Sahtoe, Willem J. van Dijk, Reggy Ekkebus, Huib Ovaa, Titia K. Sixma - Nature Communications 2016 被引用: 247
- Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis
著者: Sijia Liu, Román González‐Prieto, Mengdi Zhang, Paul P. Geurink, Raymond Kooij, Prasanna Vasudevan Iyengar, Maarten van Dinther, Erik Bos, Xiaobing Zhang, Sylvia E. Le Dévédec, Bob van de Water, Roman I. Koning, Hong‐Jian Zhu, Wilma E. Mesker, Alfred C.O. Vertegaal, Huib Ovaa, Long Zhang, John W.M. Martens, Peter ten Dijke - Clinical Cancer Research 2019 被引用: 173
- Global non-covalent SUMO interaction networks reveal SUMO-dependent stabilization of the non-homologous end joining complex
著者: Román González‐Prieto, Karolin Eifler-Olivi, Laura A. Claessens, Edwin Willemstein, Zhenyu Xiao, Cami Talavera Ormeño, Huib Ovaa, Helle D. Ulrich, Alfred C.O. Vertegaal - Cell Reports 2021 被引用: 75
- Structural basis of the specificity of USP18 toward ISG15
著者: Anja Basters, Paul P. Geurink, Annika Röcker, Katharina F. Witting, Roya Tadayon, Sandra Hess, Marta S. Semrau, Paola Storici, Huib Ovaa, Klaus‐Peter Knobeloch, G. Fritz - Nature Structural & Molecular Biology 2017 被引用: 142
- Reactive glia show increased immunoproteasome activity in Alzheimer’s disease
著者: Marie Orre, Willem Kamphuis, Stephanie Dooves, Lieneke Kooijman, Elena T. Chan, Christopher J. Kirk, Vanessa D. Smith, Sanne Koot, Carlyn Mamber, Anne H. P. Jansen, Huib Ovaa, Elly M. Hol - Brain 2013 被引用: 174
- Generation of peptide–MHC class I complexes through UV-mediated ligand exchange
著者: Boris Rodenko, Mireille Toebes, Sine Reker Hadrup, Wim J.E. van Esch, Annemieke M Molenaar, Ton N. Schumacher, Huib Ovaa - Nature Protocols 2006 被引用: 327
- The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
著者: Elma Mons, Ineke D.C. Jansen, Jure Loboda, Bjorn R. van Doodewaerd, J. P. G. Hermans, Martijn Verdoes, C. A. A. VAN BOECKEL, Peter A. van Veelen, Boris Turk, Dusan Turk, Huib Ovaa - Journal of the American Chemical Society 2019 被引用: 115
- Chemistry-Based Functional Proteomics Reveals Novel Members of the Deubiquitinating Enzyme Family
著者: Anna Borodovsky, Huib Ovaa, Nagamalleswari Kolli, Tudeviin Gan‐Erdene, Keith D. Wilkinson, Hidde L. Ploegh, Benedikt M. Kessler - Chemistry & Biology 2002 被引用: 596
- Chemical Synthesis of Ubiquitin, Ubiquitin‐Based Probes, and Diubiquitin
著者: Farid El Oualid, Remco Merkx, Reggy Ekkebus, Dharjath S. Hameed, Judith J. Smit, Annemieke de Jong, Henk Hilkmann, Titia K. Sixma, Huib Ovaa - Angewandte Chemie International Edition 2010 被引用: 322
