David C. Chan
1991–2025 年に発表
- 98
- 論文数
- 40,267
- 被引用数
- 78
- h 指数
- 96
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology53.9%
- Medicine31.5%
- Immunology and Microbiology6.4%
- Neuroscience3.9%
- Agricultural and Biological Sciences0.8%
- Environmental Science0.7%
- その他2.8%
トピック
- Mitochondrial Function and Pathology15.6%
- Autophagy in Disease and Therapy5.8%
- ATP Synthase and ATPases Research5.5%
- Metabolism and Genetic Disorders3.3%
- Adipose Tissue and Metabolism2.9%
- Endoplasmic Reticulum Stress and Disease1.6%
- その他65.3%
共著者
- Hsiuchen Chen19
- Prashant Mishra9
- J. Michael McCaffery8
- Grigor Varuzhanyan6
- Shuxia Meng6
- Zhiyin Song6
- Philip Leder5
- Scott A. Detmer5
- Valério Carelli5
- Anh H. Pham4
- Michael J. Sweredoski4
- Peter S. Kim4
- Raymond Liu4
- Anne Chomyn3
- Chun-Shik Shin3
- Hiromi Sesaki3
- Jens T. Kaiser3
- Mark S. Ladinsky3
- Oliver C. Losón3
- Rebecca Rojansky3
- Shun‐ichi Yamashita3
- Tomotake Kanki3
- Alessandra Maresca2
- Annie Moradian2
全論文
- Mitochondrial Dynamics and Its Involvement in Disease
著者: David C. Chan - Annual Review of Pathology Mechanisms of Disease 2019 被引用: 1,400
- Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
著者: Hsiuchen Chen, Scott A. Detmer, Andrew J. Ewald, Erik E. Griffin, Scott E. Fraser, David C. Chan - The Journal of Cell Biology 2003 被引用: 2,557
- AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
著者: Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L. Lewis, Oliver C. Losón, Kristina Hellberg, Nathan P. Young, Hsiuchen Chen, Franck Polleux, David C. Chan, Reuben J. Shaw - Science 2016 被引用: 1,083
- Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission
著者: Oliver C. Losón, Zhiyin Song, Hsiuchen Chen, David C. Chan - Molecular Biology of the Cell 2013 被引用: 1,209
- Metabolic regulation of mitochondrial dynamics
著者: Prashant Mishra, David C. Chan - The Journal of Cell Biology 2016 被引用: 1,108
- Solving neurodegeneration: common mechanisms and strategies for new treatments
著者: Lauren K. Wareham, Shane A. Liddelow, Sally Temple, Larry I. Benowitz, Adriana Di Polo, Cheryl L. Wellington, Jeffrey L. Goldberg, Zhigang He, Xin Duan, Guojun Bu, Albert A. Davis, Karthik Shekhar, Anna La Torre, David C. Chan, Marta Soler, John G. Flanagan, Preeti Subramanian, Sharyn L. Rossi, Thomas M. Brunner, Diane E. Bovenkamp, David J. Calkins - Molecular Neurodegeneration 2022 被引用: 307
- Mitochondrial dynamics and inheritance during cell division, development and disease
著者: Prashant Mishra, David C. Chan - Nature Reviews Molecular Cell Biology 2014 被引用: 1,033
- Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations
著者: Hsiuchen Chen, Marc Vermulst, Yun E. Wang, Anne Chomyn, Tomas A. Prolla, J. Michael McCaffery, David C. Chan - Cell 2010 被引用: 1,223
- Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health
著者: David C. Chan - Annual Review of Genetics 2011 被引用: 1,179
- Mitochondria: Dynamic Organelles in Disease, Aging, and Development
著者: David C. Chan - Cell 2006 被引用: 1,995
- Disruption of Fusion Results in Mitochondrial Heterogeneity and Dysfunction
著者: Hsiuchen Chen, Anne Chomyn, David C. Chan - Journal of Biological Chemistry 2005 被引用: 1,336
- Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
著者: Hui Chen, David C. Chan - Human Molecular Genetics 2009 被引用: 1,455
- Mitofusins and OPA1 Mediate Sequential Steps in Mitochondrial Membrane Fusion
著者: Zhiyin Song, Mariam Ghochani, J. Michael McCaffery, Terrence Frey, David C. Chan - Molecular Biology of the Cell 2009 被引用: 594
- Functions and dysfunctions of mitochondrial dynamics
著者: Scott A. Detmer, David C. Chan - Nature Reviews Molecular Cell Biology 2007 被引用: 1,358
- SLP‐2 is required for stress‐induced mitochondrial hyperfusion
著者: Daniel Tondera, Stéphanie Grandemange, Alexis A. Jourdain, Mariusz Karbowski, Yves Mattenberger, Sébastien Herzig, Sandrine Da Cruz, Pascaline Clerc, Ines Raschke, Carsten Merkwirth, Sarah Ehses, Frank Krause, David C. Chan, Christiane Alexander, Christoph Bauer, Richard J. Youle, Thomas Langer, Jean‐Claude Martinou - The EMBO Journal 2009 被引用: 766
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
著者: Nickie C. Chan, Anna M. Salazar, Anh H. Pham, Michael J. Sweredoski, Natalie J. Kolawa, R. L. Graham, Sonja Hess, David C. Chan - Human Molecular Genetics 2011 被引用: 972
- Proteolytic Cleavage of Opa1 Stimulates Mitochondrial Inner Membrane Fusion and Couples Fusion to Oxidative Phosphorylation
著者: Prashant Mishra, Valério Carelli, Giovanni Manfredi, David C. Chan - Cell Metabolism 2014 被引用: 474
- Mitochondrial Dynamics in Regulating the Unique Phenotypes of Cancer and Stem Cells
著者: Hsiuchen Chen, David C. Chan - Cell Metabolism 2017 被引用: 462
- Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
著者: Kook Hwan Kim, Yeon Taek Jeong, Hyunhee Oh, Seong‐Hun Kim, Jae Min Cho, Yona Kim, Su Sung Kim, Do‐Hoon Kim, Kyu Yeon Hur, Hyoung Kyu Kim, Tae-Hee Ko, Jin Han, Hong Lim Kim, Jin Kim, Sung Hoon Back, Masaaki Komatsu, Hsiuchen Chen, David C. Chan, Morichika Konishi, Nobuyuki Itoh, Cheol Soo Choi, Myung‐Shik Lee - Nature Medicine 2012 被引用: 768
- The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility
著者: Chun-Shik Shin, Prashant Mishra, Jeramie D. Watrous, Valério Carelli, Marilena D’Aurelio, Mohit Jain, David C. Chan - Nature Communications 2017 被引用: 301
- SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress
著者: Sadhana Samant, Hannah J. Zhang, Zhigang Hong, Vinodkumar B. Pillai, Nagalingam R. Sundaresan, Donald J. Wolfgeher, Stephen L. Archer, David C. Chan, Mahesh P. Gupta - Molecular and Cellular Biology 2013 被引用: 428
- Structural Basis of Mitochondrial Tethering by Mitofusin Complexes
著者: Takumi Koshiba, Scott A. Detmer, Jens T. Kaiser, Hsiuchen Chen, J. Michael McCaffery, David C. Chan - Science 2004 被引用: 893
- OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L
著者: Zhiyin Song, Hsiuchen Chen, Maja Fiket, Christiane Alexander, David C. Chan - The Journal of Cell Biology 2007 被引用: 810
- Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
著者: Rebecca Rojansky, Moon-Yong Cha, David C. Chan - eLife 2016 被引用: 333
