Reuben J. Shaw
1994–2025 年に発表
- 75
- 論文数
- 45,390
- 被引用数
- 62
- h 指数
- 74
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology44%
- Medicine43.6%
- Neuroscience4.8%
- Immunology and Microbiology3.1%
- Agricultural and Biological Sciences1.5%
- Nursing0.6%
- その他2.4%
トピック
- Autophagy in Disease and Therapy6.4%
- Metabolism, Diabetes, and Cancer5.9%
- Adipose Tissue and Metabolism3.8%
- Cancer, Hypoxia, and Metabolism3.3%
- Sirtuins and Resveratrol in Medicine3.1%
- Mitochondrial Function and Pathology3.1%
- その他74.4%
共著者
- Debbie S. Vasquez8
- Kristina Hellberg8
- Lewis C. Cantley8
- Lillian J. Eichner8
- Maria M. Mihaylova8
- Sonja N. Brun8
- David B. Shackelford7
- Robert Svensson7
- Debbie S. Ross6
- John M. Asara6
- Marc Montminy6
- Christian M. Metallo5
- Elijah Trefts5
- Maxim N. Shokhirev5
- Nabeel Bardeesy5
- Sébastien Herzig5
- Andrew Dillin4
- Brendan D. Manning4
- Daniel F. Egan4
- Daniel Garcia4
- Jeanine L. Van Nostrand4
- Mathias Leblanc4
- Pablo E. Hollstein4
- Stephanie D. Curtis4
全論文
- AMPK: guardian of metabolism and mitochondrial homeostasis
著者: Sébastien Herzig, Reuben J. Shaw - Nature Reviews Molecular Cell Biology 2017 被引用: 3,997
- AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance
著者: Daniel Garcia, Reuben J. Shaw - Molecular Cell 2017 被引用: 1,963
- The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
著者: Maria M. Mihaylova, Reuben J. Shaw - Nature Cell Biology 2011 被引用: 2,928
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
著者: Dana M. Gwinn, David B. Shackelford, Daniel F. Egan, Maria M. Mihaylova, Annabelle Méry, Debbie S. Vasquez, Benjamin E. Turk, Reuben J. Shaw - Molecular Cell 2008 被引用: 3,785
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
著者: Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova, Sara Gelino, Rebecca A. Kohnz, William B. Mair, Debbie S. Vasquez, Aashish Joshi, Dana M. Gwinn, Rebecca C. Taylor, John M. Asara, James A. J. Fitzpatrick, Andrew Dillin, Benoı̂t Viollet, Mondira Kundu, Malene Hansen, Reuben J. Shaw - Science 2010 被引用: 2,599
- AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
著者: Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L. Lewis, Oliver C. Losón, Kristina Hellberg, Nathan P. Young, Hsiuchen Chen, Franck Polleux, David C. Chan, Reuben J. Shaw - Science 2016 被引用: 1,083
- AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
著者: Li Yu, Shanqin Xu, Maria M. Mihaylova, Bin Zheng, Xiuyun Hou, Bingbing Jiang, Ogyi Park, Zhijun Luo, Étienne Lefai, John Y.-J. Shyy, Bin Gao, Michel Wierzbicki, Tony J. Verbeuren, Reuben J. Shaw, Richard A. Cohen, Mengwei Zang - Cell Metabolism 2011 被引用: 1,740
- AMPK: restoring metabolic homeostasis over space and time
著者: Elijah Trefts, Reuben J. Shaw - Molecular Cell 2021 被引用: 444
- Resveratrol improves health and survival of mice on a high-calorie diet
著者: Joseph A. Baur, Kevin Pearson, Nathan L. Price, Hamish A. Jamieson, Carles Lerín, Avash Kalra, Vinayakumar Prabhu, Joanne Allard, Guillermo López‐Lluch, Kaitlyn N. Lewis, Paul J. Pistell, Suresh Poosala, Kevin G. Becker, Olivier Boss, Dana M. Gwinn, Mingyi Wang, Sharan Ramaswamy, Kenneth W. Fishbein, Richard G. Spencer, Edward G. Lakatta, David G. Le Couteur, Reuben J. Shaw, Plácido Navas, Pere Puigserver, Donald K. Ingram, Rafael de Cabo, David Sinclair - Nature 2006 被引用: 4,256
- The LKB1–AMPK pathway: metabolism and growth control in tumour suppression
著者: David B. Shackelford, Reuben J. Shaw - Nature reviews. Cancer 2009 被引用: 1,927
- Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1
著者: Nazma Malik, Bibiana I. Ferreira, Pablo E. Hollstein, Stephanie D. Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca C. Gilson, Kristina Hellberg, Linjing Fang, Arlo Sheridan, Nasun Hah, Gerald S. Shadel, Uri Manor, Reuben J. Shaw - Science 2023 被引用: 202
- Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates
著者: Daniel F. Egan, Matthew G. H. Chun, Mitchell Vamos, Haixia Zou, Juan Rong, Chad J. Miller, Hua Jane Lou, Raveendra-Panickar Dhanya, Chih-Cheng Yang, Douglas J. Sheffler, Peter Teriete, John M. Asara, Benjamin E. Turk, Nicholas D. P. Cosford, Reuben J. Shaw - Molecular Cell 2015 被引用: 723
- Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
著者: Robert Svensson, Seth J. Parker, Lillian J. Eichner, Matthew J. Kolar, Martina Wallace, Sonja N. Brun, Portia S. Lombardo, Jeanine L. Van Nostrand, Amanda Hutchins, Lilliana Vera, Laurie Gerken, Jeremy R. Greenwood, Sathesh Bhat, Geraldine Harriman, William Westlin, H. James Harwood, Alan Saghatelian, Rosana Kapeller, Christian M. Metallo, Reuben J. Shaw - Nature Medicine 2016 被引用: 520
- The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
著者: Reuben J. Shaw, Katja Lamia, Debbie S. Vasquez, Seung‐Hoi Koo, Nabeel Bardeesy, Ronald A. DePinho, Marc Montminy, Lewis C. Cantley - Science 2005 被引用: 1,948
- The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
著者: Reuben J. Shaw, Monica Kosmatka, Nabeel Bardeesy, Rebecca L. Hurley, Lee A. Witters, Ronald A. DePinho, Lewis C. Cantley - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 被引用: 1,774
- Autophagic cell death restricts chromosomal instability during replicative crisis
著者: Joe Nassour, Robert J. Radford, Adriana Correia, Javier Miralles Fusté, Brigitte Schoell, Anna Jauch, Reuben J. Shaw, Jan Karlseder - Nature 2019 被引用: 425
- Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
著者: Jessica J. Howell, Kristina Hellberg, Marc Turner, George Talbott, Matthew J. Kolar, Debbie S. Ross, Gerta Hoxhaj, Alan Saghatelian, Reuben J. Shaw, Brendan D. Manning - Cell Metabolism 2017 被引用: 405
- Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1
著者: Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C. Erickson, Alissandra L. Hillis, Christian C. Dibble, John M. Asara, Gyongy Szabo, Piotr Siciński, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J. Shaw, Junying Yuan, Wenyi Wei - Science 2023 被引用: 118
- AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy
著者: Chien‐Min Hung, Portia S. Lombardo, Nazma Malik, Sonja N. Brun, Kristina Hellberg, Jeanine L. Van Nostrand, Daniel Garcia, Joshua T. Baumgart, Ken Diffenderfer, John M. Asara, Reuben J. Shaw - Science Advances 2021 被引用: 159
- AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation
著者: Katja Lamia, Uma M. Sachdeva, Luciano DiTacchio, Elliot Williams, Jacqueline G. Alvarez, Daniel F. Egan, Debbie S. Vasquez, Henry Juguilon, Satchidananda Panda, Reuben J. Shaw, Craig B. Thompson, Ronald M. Evans - Science 2009 被引用: 949
- MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size
著者: Tommy L. Lewis, Seok‐Kyu Kwon, Annie Lee, Reuben J. Shaw, Franck Polleux - Nature Communications 2018 被引用: 282
- The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
著者: Dan Egan, Joungmok Kim, Reuben J. Shaw, Kun‐Liang Guan - Autophagy 2011 被引用: 633
- Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD
著者: Daniel Garcia, Kristina Hellberg, Amandine Chaix, Martina Wallace, Sébastien Herzig, Mehmet G. Badur, Terry Lin, Maxim N. Shokhirev, Antônio F. M. Pinto, Debbie S. Ross, Alan Saghatelian, Satchidananda Panda, Lukas E. Dow, Christian M. Metallo, Reuben J. Shaw - Cell Reports 2019 被引用: 302
- Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy
著者: Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis, So Yeon Koo, Archana Ashok, Georges Mairet‐Coello, Sébastien Herzig, Marc Foretz, Benoı̂t Viollet, Reuben J. Shaw, Andrew A. Sproul, Franck Polleux - Nature Communications 2022 被引用: 110
