David Carling
1987–2025 年に発表
- 127
- 論文数
- 50,876
- 被引用数
- 94
- h 指数
- 124
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology44.8%
- Medicine40.5%
- Neuroscience6.9%
- Agricultural and Biological Sciences2.3%
- Immunology and Microbiology2%
- Nursing1.2%
- その他2.3%
トピック
- Metabolism, Diabetes, and Cancer8.7%
- Adipose Tissue and Metabolism7%
- Pancreatic function and diabetes4.3%
- Adipokines, Inflammation, and Metabolic Diseases4.2%
- Regulation of Appetite and Obesity2.6%
- Diet and metabolism studies2.5%
- その他70.7%
共著者
- Angela Woods30
- D. Grahame Hardie25
- Lee G.D. Fryer11
- Matthew J. Sanders9
- Benoı̂t Viollet7
- Richard Heath7
- S.J. Gamblin7
- Alice Pollard6
- Fabienne Foufelle6
- Phillip Muckett6
- Raj K. Beri6
- Stephen Davies6
- Bing Xiao5
- Gregory R. Steinberg5
- Lucy Penfold5
- Marc Foretz5
- Marian Carlson5
- Stephen R. Bloom5
- Stephen R. Martin5
- Anissa A. Widjaja4
- Barbara B. Kahn4
- Ben Jones4
- Chad Whilding4
- Claire Thornton4
全論文
- The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism
著者: Gary Frost, Michelle Sleeth, Meliz Sahuri-Arisoylu, Blanca Lizarbe, Sebastián Cerdán, Leigh Brody, Jelena Anastasovska, Samar Ghourab, Mohammed K. Hankir, Shuai Zhang, David Carling, Jonathan R. Swann, Glenn R. Gibson, Alexander Viardot, Douglas J. Morrison, E. Louise Thomas, Jimmy D. Bell - Nature Communications 2014 被引用: 1,739
- AMP-activated protein kinase: the current landscape for drug development
著者: Gregory R. Steinberg, David Carling - Nature Reviews Drug Discovery 2019 被引用: 749
- AMPK signalling in health and disease
著者: David Carling - Current Opinion in Cell Biology 2017 被引用: 802
- Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
著者: Toshimasa Yamauchi, Junji Kamon, Yasuhiko Minokoshi, Yusuke Ito, Hironori Waki, Shoko Uchida, Satoshi Yamashita, Mitsuhiko Noda, Shunbun Kita, Kohjiro Ueki, Kazuhiro Eto, Y Akanuma, Philippe Froguel, Fabienne Foufelle, Pascal Ferré, David Carling, Satoshi Kimura, R Nagai, Barbara B. Kahn, Takashi Kadowaki - Nature Medicine 2002 被引用: 4,221
- Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
著者: Anissa A. Widjaja, Wei‐Wen Lim, Siva Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schäfer, Benjamin L. George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A. Sims, Norbert Hübner, Enrico Petretto, Dominic J. Withers, Lena Ho, Jesús Gil, David Carling, Stuart A. Cook - Nature 2024 被引用: 209
- Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
著者: Angela Woods, Kristina Dickerson, Richard Heath, Seung Pyo Hong, Milica Momcilovic, Stephen R. Johnstone, Marian Carlson, David Carling - Cell Metabolism 2005 被引用: 1,387
- AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
著者: Barbara B. Kahn, Thierry Alquier, David Carling, D. Grahame Hardie - Cell Metabolism 2005 被引用: 2,793
- Adenosine 5′-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype
著者: Duygu Sağ, David Carling, Robert D. Stout, Jill Suttles - The Journal of Immunology 2008 被引用: 796
- AMPK, insulin resistance, and the metabolic syndrome
著者: Neil B. Ruderman, David Carling, Marc Prentki, José M. Cacicedo - Journal of Clinical Investigation 2013 被引用: 867
- LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
著者: Angela Woods, Stephen R. Johnstone, Kristina Dickerson, Fiona C. Leiper, Lee G.D. Fryer, Dietbert Neumann, Uwe Schlattner, Theo Wallimann, Marian Carlson, David Carling - Current Biology 2003 被引用: 1,646
- Structure of mammalian AMPK and its regulation by ADP
著者: Bing Xiao, Matthew J. Sanders, E. Underwood, Richard Heath, Faith V. Mayer, David Carmena, Chun Jing, P.A. Walker, John F. Eccleston, L.F. Haire, Peter Saiu, Steven Howell, Rein Aasland, Stephen R. Martin, David Carling, S.J. Gamblin - Nature 2011 被引用: 927
- Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly
著者: Elizabeth C. Hinchy, Anja V. Gruszczyk, Robin Willows, Naveenan Navaratnam, Andrew Hall, Georgina Bates, Thomas P. Bright, Thomas Krieg, David Carling, Michael P. Murphy - Journal of Biological Chemistry 2018 被引用: 303
- Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
著者: Yasuhiko Minokoshi, Young‐Bum Kim, Odile D. Peroni, Lee G.D. Fryer, Corinna Müller, David Carling, Barbara B. Kahn - Nature 2002 被引用: 2,054
- Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase
著者: Simon A. Hawley, Matt Davison, Angela Woods, Stephen Davies, Raj K. Beri, David Carling, D. Grahame Hardie - Journal of Biological Chemistry 1996 被引用: 1,262
- Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
著者: Colin Selman, Jennifer M. A. Tullet, Daniela Wieser, Elaine E. Irvine, Steven J. Lingard, Agharul I. Choudhury, Marc Claret, Hind Al‐Qassab, Danielle Carmignac, Faruk Ramadani, Angela Woods, Iain C. A. F. Robinson, Eugene F. Schuster, Rachel L. Batterham, Sara C. Kozma, George Thomas, David Carling, Klaus Okkenhaug, Janet M. Thornton, Linda Partridge, David Gems, Dominic J. Withers - Science 2009 被引用: 1,131
- Structural basis of AMPK regulation by small molecule activators
著者: Bing Xiao, Matthew J. Sanders, David Carmena, Nicola J. Bright, L.F. Haire, E. Underwood, Bhakti Patel, Richard Heath, P.A. Walker, Stefan Hallén, Fabrizio Giordanetto, Stephen R. Martin, David Carling, S.J. Gamblin - Nature Communications 2013 被引用: 543
- Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
著者: A-S. Marsin, Luc Bertrand, Mark H. Rider, Johan Deprez, Christophe Beauloye, M. F. Vincent, Greet Van den Berghe, David Carling, Louis Hue - Current Biology 2000 被引用: 824
- A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis
著者: David Carling, Victor A. Zammit, D. Grahame Hardie - FEBS Letters 1987 被引用: 594
- Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
著者: Miguel López, Luis Varela, María J. Vázquez, Sergio Rodríguez‐Cuenca, C. Ruth González, Vidya Velagapudi, Donald A. Morgan, Erik Schoenmakers, Khristofor Agassandian, Ricardo Lage, Pablo B. Martínez de Morentin, Sulay Tovar, Rubén Nogueiras, David Carling, Christopher J. Lelliott, Rosalı́a Gallego, Matej Orešič, Krishna Chatterjee, Asish K. Saha, Kamal Rahmouni, Carlos Diéguez, Antonio Vidal‐Puig - Nature Medicine 2010 被引用: 676
- Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells
著者: Robin Willows, Matthew J. Sanders, Bing Xiao, Bhakti Patel, Stephen R. Martin, Jon Read, J. Wilson, Julia Hubbard, S.J. Gamblin, David Carling - Biochemical Journal 2017 被引用: 181
- Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet
著者: Angela Woods, Jennet Williams, Phillip Muckett, Faith V. Mayer, Maria Liljevald, Mohammad Bohlooly‐Y, David Carling - Cell Reports 2017 被引用: 207
- Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis
著者: Pascale Gluais Dagorn, Marc Foretz, Gregory R. Steinberg, Battsetseg Batchuluun, Anna Zawistowska‐Deniziak, Joost M. Lambooij, Bruno Guigas, David Carling, Pierre‐Axel Monternier, David E. Moller, Sébastien Bolze, Sophie Hallakou‐Bozec - Hepatology Communications 2021 被引用: 77
- Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma
著者: Anke Nijhuis, Arti Sikka, Orli Yogev, Lili Herendi, Cristina Balcells, Yurui Ma, Evon Poon, Clare Eckold, Gabriel N. Valbuena, Yuewei Xu, Yusong Liu, Barbara Martins Da Costa, Michael Gruet, Chiharu Wickremesinghe, Adrián Benito, Holger Kramer, Alex Montoya, David Carling, Elizabeth J. Want, Yann Jamin, Louis Chesler, Hector C. Keun - Nature Communications 2022 被引用: 117
- AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue
著者: Alice Pollard, Luís Martins, Phillip Muckett, Sanjay Khadayate, Aurélie Bornot, Maryam Clausen, Therése Admyre, Mikael Bjursell, Rebeca Fiadeiro, Laura Wilson, Chad Whilding, Vassilios N. Kotiadis, Michael R. Duchen, Daniel Sutton, Lucy Penfold, Alessandro Sardini, Mohammad Bohlooly‐Y, David M. Smith, Jon Read, Michael Snowden, Angela Woods, David Carling - Nature Metabolism 2019 被引用: 110
