Simon A. Hawley
1994–2024 年に発表
- 46
- 論文数
- 24,430
- 被引用数
- 43
- h 指数
- 46
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology51.7%
- Medicine35.8%
- Neuroscience4.2%
- Immunology and Microbiology2.7%
- Agricultural and Biological Sciences2.7%
- Nursing0.7%
- その他2.2%
トピック
- Metabolism, Diabetes, and Cancer12.8%
- Pancreatic function and diabetes6.6%
- Adipose Tissue and Metabolism5%
- Autophagy in Disease and Therapy4.1%
- Cancer, Hypoxia, and Metabolism3.3%
- Mitochondrial Function and Pathology2.5%
- その他65.7%
共著者
- D. Grahame Hardie44
- Fiona A. Ross12
- Kirsty J. Mustard6
- Kevin A. Green5
- Benoı̂t Viollet4
- David Carling4
- Gregory R. Steinberg4
- Ian P. Salt4
- Kei Sakamoto4
- Angela Woods3
- Chen‐Song Zhang3
- David Pan3
- Douglas J. Lamont3
- Fiona M. Russell3
- Graeme J. Gowans3
- Hai‐long Piao3
- Jin-Wei Feng3
- John W. Scott3
- Mengqi Li3
- Sarah Fogarty3
- Sheng‐Cai Lin3
- Stephen Davies3
- Zhichao Wang3
- Abdelmadjid Atrih2
全論文
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
著者: D. Grahame Hardie, Fiona A. Ross, Simon A. Hawley - Nature Reviews Molecular Cell Biology 2012 被引用: 4,473
- Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
著者: Chen‐Song Zhang, Simon A. Hawley, Yue Zong, Mengqi Li, Zhichao Wang, Alexander Gray, Teng Ma, Jiwen Cui, Jin-Wei Feng, Mingjiang Zhu, Yuqing Wu, Terytty Yang Li, Zhiyun Ye, Shu‐Yong Lin, Huiyong Yin, Hai‐long Piao, D. Grahame Hardie, Sheng‐Cai Lin, Sheng‐Cai Lin, Sheng‐Cai Lin - Nature 2017 被引用: 736
- Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy
著者: Joshua C. Drake, Rebecca J. Wilson, Rhianna C. Laker, Yuntian Guan, Hannah R. Spaulding, Anna S. Nichenko, Wenqing Shen, Huayu Shang, Maya V. Dorn, Kian A Huang, Mei Zhang, Aloka B. Bandara, Matthew H. Brisendine, Jennifer A. Kashatus, Poonam Sharma, A. P. Young, Jitendra Gautam, Ruofan Cao, Horst Wallrabe, Paul Chang, Michael Wong, Eric M. Desjardins, Simon A. Hawley, George J. Christ, David F. Kashatus, Clint L. Miller, Matthew J. Wolf, Ammasi Periasamy, Gregory R. Steinberg, D. Grahame Hardie, Zhen Yan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 被引用: 196
- Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
著者: Simon A. Hawley, David Pan, Kirsty J. Mustard, Louise C. Ross, Jenny Bain, Arthur Edelman, Bruno G. Frenguelli, D. Grahame Hardie - Cell Metabolism 2005 被引用: 1,567
- The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels
著者: Simon A. Hawley, Rebecca J. Ford, Brennan K. Smith, Graeme J. Gowans, Sarah J. Mancini, Ryan D. Pitt, Emily A. Day, Ian P. Salt, Gregory R. Steinberg, D. Grahame Hardie - Diabetes 2016 被引用: 386
- LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
著者: José M. Lizcano, Olga Göransson, Rachel Toth, Mária Deák, Nick Morrice, Jérôme Boudeau, Simon A. Hawley, Lina Udd, Tomi P. Mäkelä, D. Grahame Hardie, Dario R. Alessi - The EMBO Journal 2004 被引用: 1,372
- Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
著者: Simon A. Hawley, Fiona A. Ross, Cyrille Chevtzoff, Kevin A. Green, A. Mark Evans, Sarah Fogarty, Mhairi C. Towler, Laura A. Brown, Oluseye A. Ogunbayo, A. Mark Evans, D. Grahame Hardie - Cell Metabolism 2010 被引用: 763
- Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase
著者: Simon A. Hawley, Matt Davison, Angela Woods, Stephen Davies, Raj K. Beri, David Carling, D. Grahame Hardie - Journal of Biological Chemistry 1996 被引用: 1,262
- Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade
著者: Simon A. Hawley, Jérôme Boudeau, Jennifer L. Reid, Kirsty J. Mustard, Lina Udd, Tomi P. Mäkelä, Dario R. Alessi, D. Grahame Hardie - Journal of Biology 2003 被引用: 1,640
- The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
著者: Simon A. Hawley, Morgan D. Fullerton, Fiona A. Ross, Jonathan D. Schertzer, Cyrille Chevtzoff, Katherine J. Walker, Mark Peggie, Darya Zibrova, Kevin A. Green, Kirsty J. Mustard, Bruce E. Kemp, Kei Sakamoto, Gregory R. Steinberg, D. Grahame Hardie - Science 2012 被引用: 739
- Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis
著者: Richard M. Reznick, Haihong Zong, Ji Li, Katsutaro Morino, Irene K. Moore, Hannah J. Yu, Zhen-Xiang Liu, Jianying Dong, Kirsty J. Mustard, Simon A. Hawley, Douglas E. Befroy, Marc Pypaert, D. Grahame Hardie, Lawrence H. Young, Gerald I. Shulman - Cell Metabolism 2007 被引用: 541
- Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress
著者: Yue Zong, Chen‐Song Zhang, Mengqi Li, Wen Wang, Zhichao Wang, Simon A. Hawley, Teng Ma, Jin-Wei Feng, Xiao Tian, Qi Qu, Yuqing Wu, Cixiong Zhang, Zhiyun Ye, Shu‐Yong Lin, Hai‐long Piao, D. Grahame Hardie, Sheng‐Cai Lin, Sheng‐Cai Lin, Sheng‐Cai Lin - Cell Research 2019 被引用: 172
- 5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?
著者: Julia M. Corton, John G. Gillespie, Simon A. Hawley, D. Grahame Hardie - European Journal of Biochemistry 1995 被引用: 1,189
- AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
著者: Graeme J. Gowans, Simon A. Hawley, Fiona A. Ross, D. Grahame Hardie - Cell Metabolism 2013 被引用: 523
- Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
著者: Mengqi Li, Chen‐Song Zhang, Jin-Wei Feng, Xiaoyan Wei, Cixiong Zhang, Changchuan Xie, Yaying Wu, Simon A. Hawley, Abdelmadjid Atrih, Douglas J. Lamont, Zhichao Wang, Hai-long Piao, D. Grahame Hardie, Sheng‐Cai Lin - Cell Research 2020 被引用: 80
- Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase
著者: Olga Göransson, Andrew McBride, Simon A. Hawley, Fiona A. Ross, Natalia Shpiro, Marc Foretz, Benoı̂t Viollet, D. Grahame Hardie, Kei Sakamoto - Journal of Biological Chemistry 2007 被引用: 438
- AMP‐activated protein kinase – development of the energy sensor concept
著者: D. Grahame Hardie, Simon A. Hawley, John W. Scott - The Journal of Physiology 2006 被引用: 807
- AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern
著者: D. Grahame Hardie, Fiona A. Ross, Simon A. Hawley - Chemistry & Biology 2012 被引用: 371
- CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations
著者: John W. Scott, Simon A. Hawley, Kevin A. Green, Miliea Anis, G. A. Stewart, Gillian A. Scullion, D. Norman, D. Grahame Hardie - Journal of Clinical Investigation 2004 被引用: 725
- The Antidiabetic Drug Metformin Activates the AMP-Activated Protein Kinase Cascade via an Adenine Nucleotide-Independent Mechanism
著者: Simon A. Hawley, Anne E. Gadalla, Grith Skytte Olsen, D. Grahame Hardie - Diabetes 2002 被引用: 688
- Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes
著者: Péter Tamás, Simon A. Hawley, Rosemary G. Clarke, Kirsty J. Mustard, Kevin Green, D. Grahame Hardie, Doreen A. Cantrell - The Journal of Experimental Medicine 2006 被引用: 325
- Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells
著者: Simon A. Hawley, Fiona A. Ross, Graeme J. Gowans, Priyanka Tibarewal, Nicholas R. Leslie, D. Grahame Hardie - Biochemical Journal 2014 被引用: 206
- Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK
著者: Roger W. Hunter, Marc Foretz, Laurent Bultot, Morgan D. Fullerton, Mária Deák, Fiona A. Ross, Simon A. Hawley, Natalia Shpiro, Benoı̂t Viollet, Denís Barron, Bruce E. Kemp, Gregory R. Steinberg, D. Grahame Hardie, Kei Sakamoto - Chemistry & Biology 2014 被引用: 125
- Mechanism of Activation of AMPK by Cordycepin
著者: Simon A. Hawley, Fiona A. Ross, Fiona M. Russell, Abdelmadjid Atrih, Douglas J. Lamont, D. Grahame Hardie - Cell chemical biology 2020 被引用: 63
