David W. Speicher
1980–2025 年に発表
- 122
- 論文数
- 23,906
- 被引用数
- 86
- h 指数
- 120
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology54.4%
- Medicine28.4%
- Immunology and Microbiology6%
- Chemistry3.8%
- Neuroscience1.8%
- Engineering1.8%
- その他3.8%
トピック
- Cellular Mechanics and Interactions3.6%
- Epigenetics and DNA Methylation2.6%
- RNA Research and Splicing2.2%
- Genomics and Chromatin Dynamics2%
- Cancer Cells and Metastasis1.9%
- Immune cells in cancer1.9%
- その他85.8%
共著者
- Hsin‐Yao Tang36
- Andrew V. Kossenkov32
- Qin Liu20
- Meenhard Herlyn15
- Rugang Zhang14
- Xiaowei Xu12
- Aaron R. Goldman10
- Dario C. Altieri10
- Lucia R. Languino10
- Ronen Marmorstein9
- Kaye D. Speicher8
- Ravi K. Amaravadi8
- Vito W. Rebecca8
- Dmitry I. Gabrilovich7
- Ekta Agarwal7
- Jae Ho Seo7
- Jagadish C. Ghosh7
- Sandra L. Harper7
- Shuai Wu7
- Ashani T. Weeraratna6
- Benjamin G. Bitler6
- Dennis E. Discher6
- Gretchen M. Alicea6
- José R. Conejo-García6
全論文
- Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
著者: Joe Swift, Irena L. Ivanovska, Amnon Buxboim, Takamasa Harada, P.C. Dave P. Dingal, Joel Pinter, J. David Pajerowski, Kyle Spinler, Jae‐Won Shin, Manorama Tewari, Florian Rehfeldt, David W. Speicher, Dennis E. Discher - Science 2013 被引用: 2,059
- Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
著者: Vinit Kumar, Laxminarasimha Donthireddy, Douglas Marvel, Thomas Condamine, Fang Wang, Sergio Lavilla-Alonso, Ayumi Hashimoto, Prashanthi Vonteddu, Reeti Behera, Marlee A. Goins, Charles Mulligan, Brian Nam, Neil Hockstein, Fred Denstman, Shanti Shakamuri, David W. Speicher, Ashani T. Weeraratna, Timothy Chao, Robert H. Vonderheide, Lucia R. Languino, Peter Ordentlich, Qin Liu, Xiaowei Xu, Albert Lo, Ellen Puré, Chunsheng Zhang, Andrey Loboda, Manuel A. Sepúlveda, Linda A. Snyder, Dmitry I. Gabrilovich - Cancer Cell 2017 被引用: 647
- NAD+ metabolism governs the proinflammatory senescence-associated secretome
著者: Timothy Nacarelli, Lena Lau, Takeshi Fukumoto, Joseph A. Zundell, Nail Fatkhutdinov, Shuai Wu, Katherine M. Aird, Osamu Iwasaki, Andrew V. Kossenkov, D. Schultz, Ken-ichi Noma, Joseph A. Baur, Zachary T. Schug, Hsin‐Yao Tang, David W. Speicher, Gregory David, Rugang Zhang - Nature Cell Biology 2019 被引用: 396
- Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility
著者: Amanpreet Kaur, Brett L. Ecker, Stephen M. Douglass, Curtis H. Kugel, Marie R. Webster, Filipe V. Almeida, Rajasekharan Somasundaram, James E. Hayden, Ehsan Ban, Hossein Ahmadzadeh, Janusz Franco‐Barraza, Neelima Shah, Ian A. Mellis, Frederick Keeney, Andrew V. Kossenkov, Hsin‐Yao Tang, Xiangfan Yin, Qin Liu, Xiaowei Xu, Mitchell E. Fane, Patricia Brafford, Meenhard Herlyn, David W. Speicher, Jennifer A. Wargo, Michael T. Tetzlaff, Lauren E. Haydu, Arjun Raj, Vivek B. Shenoy, Edna Cukierman, Ashani T. Weeraratna - Cancer Discovery 2018 被引用: 415
- Stromal changes in the aged lung induce an emergence from melanoma dormancy
著者: Mitchell E. Fane, Yash Chhabra, Gretchen M. Alicea, Devon A. Maranto, Stephen M. Douglass, Marie R. Webster, Vito W. Rebecca, Gloria E. Marino, Filipe V. Almeida, Brett L. Ecker, Daniel J. Zabransky, Laura Hüser, Thomas Beer, Hsin‐Yao Tang, Andrew V. Kossenkov, Meenhard Herlyn, David W. Speicher, Wei Xu, Xiaowei Xu, Elizabeth M. Jaffee, Julio A. Aguirre‐Ghiso, Ashani T. Weeraratna - Nature 2022 被引用: 178
- RETRACTED ARTICLE: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
著者: Amanpreet Kaur, Marie R. Webster, Katie Marchbank, Reeti Behera, Abibatou Ndoye, Curtis H. Kugel, Vanessa Dang, Jessica Appleton, Michael P. O’Connell, Phil F. Cheng, Alexander A. Valiga, Rachel Morissette, Nazli B. McDonnell, Luigi Ferrucci, Andrew V. Kossenkov, Katrina Meeth, Hsin‐Yao Tang, Xiangfan Yin, William H. Wood, Elin Lehrmann, Kevin G. Becker, Keith T. Flaherty, Dennie T. Frederick, Jennifer A. Wargo, Zachary A. Cooper, Michael T. Tetzlaff, Courtney W. Hudgens, Katherine M. Aird, Rugang Zhang, Xiaowei Xu, Qin Liu, Edmund K. Bartlett, Giorgos C. Karakousis, Zeynep Eroglu, Roger S. Lo, Matthew Chan, Alexander M. Menzies, Georgina V. Long, Douglas B. Johnson, Jeffrey A. Sosman, Bastian Schilling, Dirk Schadendorf, David W. Speicher, Marcus Bosenberg, Antoni Ribas, Ashani T. Weeraratna - Nature 2016 被引用: 390
- Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
著者: Benjamin G. Bitler, Katherine M. Aird, Azat Garipov, Hua Li, Michael Amatangelo, Andrew V. Kossenkov, D. Schultz, Qin Liu, Ie‐Ming Shih, José R. Conejo-García, David W. Speicher, Rugang Zhang - Nature Medicine 2015 被引用: 680
- Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells
著者: Alexander Roesch, Adina Vultur, Ivan Bogeski, Huan Wang, Katharina Zimmermann, David W. Speicher, Christina Körbel, Matthias W. Laschke, Phyllis A. Gimotty, Stephan Philipp, Elmar Krause, Sylvie Pätzold, Jessie Villanueva, Clemens Krepler, Mizuho Fukunaga‐Kalabis, Markus Hoth, Boris C. Bastian, Thomas Vogt, Meenhard Herlyn - Cancer Cell 2013 被引用: 673
- HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors
著者: Lei Guan, Bin Wu, Ting Li, Lynn A. Beer, Gaurav Sharma, Mingyue Li, Chin Nien Lee, Shujing Liu, Changsong Yang, Lili Huang, Dennie T. Frederick, Genevieve M. Boland, Guang-Can Shao, Tatyana Svitkina, Kathy Q. Cai, Fangping Chen, Meng‐Qiu Dong, Gordon B. Mills, Lynn M. Schuchter, Giorgos C. Karakousis, Tara C. Mitchell, Keith T. Flaherty, David W. Speicher, Youhai H. Chen, Meenhard Herlyn, Ravi K. Amaravadi, Xiaowei Xu, Wei Guo - Nature Communications 2022 被引用: 84
- Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma
著者: Shuai Wu, Takeshi Fukumoto, Jianhuang Lin, Timothy Nacarelli, Yemin Wang, Dionzie Ong, Heng Liu, Nail Fatkhutdinov, Joseph A. Zundell, Sergey Karakashev, Wei Zhou, Lauren E. Schwartz, Hsin‐Yao Tang, Ronny Drapkin, Qin Liu, David G. Huntsman, Andrew V. Kossenkov, David W. Speicher, Zachary T. Schug, Chi V. Dang, Rugang Zhang - Nature Cancer 2021 被引用: 125
- PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer
著者: Vito W. Rebecca, Michael C. Nicastri, Colin Fennelly, Cynthia I. Chude, Julie S. Barber-Rotenberg, Amruta Ronghe, Quentin McAfee, Noel P. McLaughlin, Gao Zhang, Aaron R. Goldman, Rani Ojha, Shengfu Piao, Estela Noguera-Ortega, Alessandra Martorella, Gretchen M. Alicea, Jennifer J. Lee, Lynn M. Schuchter, Xiaowei Xu, Meenhard Herlyn, Ronen Marmorstein, Phyllis A. Gimotty, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi - Cancer Discovery 2018 被引用: 246
- Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2
著者: Gretchen M. Alicea, Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera, Marie R. Webster, Curtis H. Kugel, Brett L. Ecker, M. Cecilia Caino, Andrew V. Kossenkov, Hsin‐Yao Tang, Dennie T. Frederick, Keith T. Flaherty, Xiaowei Xu, Qin Liu, Dmitry I. Gabrilovich, Meenhard Herlyn, Ian A. Blair, Zachary T. Schug, David W. Speicher, Ashani T. Weeraratna - Cancer Discovery 2020 被引用: 153
- The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
著者: Jae Ho Seo, Dayana B. Rivadeneira, M. Cecilia Caino, Young Chan Chae, David W. Speicher, Hsin‐Yao Tang, Valentina Vaira, Silvano Bòsari, A. Palleschi, Paolo Rampini, Andrew V. Kossenkov, Lucia R. Languino, Dario C. Altieri - PLoS Biology 2016 被引用: 181
- Lysosomal lipid peroxidation regulates tumor immunity
著者: Monika Bhardwaj, Jennifer J. Lee, Amanda M. Versace, Sandra L. Harper, Aaron R. Goldman, Mary Ann S. Crissey, Vaibhav Jain, Mahendra Pal Singh, Mégane Vernon, Andrew E. Aplin, Seokwoo Lee, Masao Morita, Jeffrey D. Winkler, Qin Liu, David W. Speicher, Ravi K. Amaravadi - Journal of Clinical Investigation 2023 被引用: 55
- Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A
著者: Robert E. Handschumacher, Matthew W. Harding, Jeffrey S. Rice, Rhett J Drugge, David W. Speicher - Science 1984 被引用: 1,683
- Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
著者: Adam J. Engler, Christine C. Krieger, Colin P. Johnson, Matthew Raab, Hsin‐Yao Tang, David W. Speicher, Joseph W. Sanger, Jean M. Sanger, Dennis E. Discher - Journal of Cell Science 2008 被引用: 869
- Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming
著者: Young Chan Chae, Valentina Vaira, M. Cecilia Caino, Hsin‐Yao Tang, Jae Ho Seo, Andrew V. Kossenkov, Luisa Ottobrini, Cristina Martelli, Giovanni Lucignani, Irene Bertolini, Marco Locatelli, Kelly G. Bryant, Jagadish C. Ghosh, Sofia Lisanti, Bonsu Ku, Silvano Bòsari, Lucia R. Languino, David W. Speicher, Dario C. Altieri - Cancer Cell 2016 被引用: 214
- PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma
著者: Gaurav Sharma, Rani Ojha, Estela Noguera-Ortega, Vito W. Rebecca, John Attanasio, Shujing Liu, Shengfu Piao, Jennifer J. Lee, Michael C. Nicastri, Sandra L. Harper, Amruta Ronghe, Vaibhav Jain, Jeffrey D. Winkler, David W. Speicher, Jérôme Mastio, Phyllis A. Gimotty, Xiaowei Xu, E. John Wherry, Dmitry I. Gabrilovich, Ravi K. Amaravadi - JCI Insight 2020 被引用: 78
- A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles
著者: Vito W. Rebecca, Michael C. Nicastri, Noel P. McLaughlin, Colin Fennelly, Quentin McAfee, Amruta Ronghe, Michel Nofal, Chun-Yan Lim, Eric S. Witze, Cynthia I. Chude, Gao Zhang, Gretchen M. Alicea, Shengfu Piao, Sengottuvelan Murugan, Rani Ojha, Samuel M. Levi, Zhi Wei, Julie S. Barber-Rotenberg, Maureen E. Murphy, Gordon B. Mills, Yiling Lu, Joshua D. Rabinowitz, Ronen Marmorstein, Qin Liu, Shujing Liu, Xiaowei Xu, Meenhard Herlyn, Roberto Zoncu, Donita C. Brady, David W. Speicher, Jeffrey D. Winkler, Ravi K. Amaravadi - Cancer Discovery 2017 被引用: 206
- Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy
著者: Evgenii N. Tcyganov, Emilio Sanseviero, Douglas Marvel, Thomas Beer, Hsin‐Yao Tang, Peter Hembach, David W. Speicher, Qianfei Zhang, Laxminarasimha Donthireddy, Mostafa Ali, Sabina Tsyganova, В. М. Писарев, Terri M. Laufer, Dmitriy Ignatov, Soldano Ferrone, Christiane Meyer, Hélène Maby–El Hajjami, Daniel E. Speiser, Sooner Altiok, Scott Antonia, Xiaowei Xu, Wei Xu, Cathy Zheng, Lynn M. Schuchter, Ravi K. Amaravadi, Tara C. Mitchell, Giorgos C. Karakousis, Zhe Yuan, Luis J. Montaner, Esteban Celis, Dmitry I. Gabrilovich - Cancer Cell 2022 被引用: 50
- ARID1A-mutated ovarian cancers depend on HDAC6 activity
著者: Benjamin G. Bitler, Shuai Wu, Pyoung Hwa Park, Yang Hai, Katherine M. Aird, Yemin Wang, Yali Zhai, Andrew V. Kossenkov, Ana Vara-Ailor, Frank J. Rauscher, Weiping Zou, David W. Speicher, David G. Huntsman, José R. Conejo-García, Kathleen R. Cho, David W. Christianson, Rugang Zhang - Nature Cell Biology 2017 被引用: 231
- ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay
著者: Masayuki Sakurai, Yusuke Shiromoto, Hiromitsu Ota, Chunzi Song, Andrew V. Kossenkov, Jayamanna Wickramasinghe, Louise C. Showe, Emmanuel Skordalakes, Hsin‐Yao Tang, David W. Speicher, Kazuko Nishikura - Nature Structural & Molecular Biology 2017 被引用: 148
- Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice
著者: Ming-Hui Fan, Qiang Zhu, Huihua Li, Hyun-Jeong Ra, Sonali Majumdar, Dexter L. Gulick, Jacob A. Jerome, Daniel H. Madsen, Melpo Christofidou‐Solomidou, David W. Speicher, William W. Bachovchin, Carol Feghali‐Bostwick, Ellen Puré - Journal of Biological Chemistry 2015 被引用: 125
- Uncovering Thousands of New Peptides with Sequence-Mask-Search Hybrid De Novo Peptide Sequencing Framework
著者: Korrawe Karunratanakul, Hsin‐Yao Tang, David W. Speicher, Ekapol Chuangsuwanich, Sira Sriswasdi - Molecular & Cellular Proteomics 2019 被引用: 78
