Edward H. Koo
1988–2024 年に発表
- 103
- 論文数
- 29,177
- 被引用数
- 83
- h 指数
- 103
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine63.5%
- Biochemistry, Genetics and Molecular Biology20.3%
- Neuroscience11.8%
- Computer Science0.9%
- Immunology and Microbiology0.7%
- Nursing0.5%
- その他2.3%
トピック
- Alzheimer's disease research and treatments21.6%
- Cholinesterase and Neurodegenerative Diseases5.3%
- Computational Drug Discovery Methods4.4%
- Neuroinflammation and Neurodegeneration Mechanisms4%
- Dementia and Cognitive Impairment Research2.8%
- Prion Diseases and Protein Misfolding2.3%
- その他59.6%
共著者
- Dennis J. Selkoe17
- Todd E. Golde13
- David E. Kang10
- Sascha Weggen9
- Christian Haass8
- Jason L. Eriksen8
- Salvador Soriano8
- Sangram S. Sisodia8
- Sarah A. Sagi8
- Claus U. Pietrzik7
- David B. Teplow7
- Donald L. Price7
- Christopher Chen6
- Dale E. Bredesen6
- Hui Zheng6
- Weiming Xia6
- Daniel C. Lu5
- Eliezer Masliah5
- Jimin Zhang5
- Sheue-Houy Tyan5
- Simone Eggert5
- Thomas Kukar5
- Barbara A. Cottrell4
- Beth L. Ostaszewski4
全論文
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
著者: Adam C. Naj, Gyungah Jun, Gary W. Beecham, Li‐San Wang, Badri N. Vardarajan, Jacqueline L. Buros, Paul J. Gallins, Joseph D. Buxbaum, Gail P. Jarvik, Paul K. Crane, Eric B. Larson, Thomas D. Bird, Bradley F. Boeve, Neill R. Graff‐Radford, Philip L. De Jager, Denis A. Evans, Julie A. Schneider, Minerva M. Carrasquillo, Nilüfer Ertekin‐Taner, Steven G. Younkin, Carlos Cruchaga, John Kauwe, Petra Nowotny, Patricia Kramer, John Hardy, Matthew J. Huentelman, Amanda Myers, M. Michael Barmada, F. Yesim Demirci, Clinton T. Baldwin, Robert C. Green, Ekaterina Rogaeva, Peter St George‐Hyslop, Steven E. Arnold, Robert C. Barber, Thomas G. Beach, Eileen H. Bigio, James D. Bowen, Adam Boxer, James R. Burke, Nigel J. Cairns, Chris Carlson, Regina M. Carney, Steven L. Carroll, Helena C. Chui, David G. Clark, Jason J. Corneveaux, Carl W. Cotman, Jeffrey L. Cummings, Charles DeCarli, Steven T. DeKosky, Ramon Diaz‐Arrastia, Malcolm Dick, Dennis W. Dickson, William G. Ellis, Kelley M. Faber, Kenneth B. Fallon, Martin R. Farlow, Steven H. Ferris, Matthew P. Frosch, Douglas Galasko, Mary Ganguli, Marla Gearing, Daniel H. Geschwind, Bernardino Ghetti, John R. Gilbert, Sid Gilman, Bruno Giordani, Jonathan D. Glass, John H. Growdon, Ronald L. Hamilton, Lindy E. Harrell, Elizabeth Head, Lawrence S. Honig, Christine M. Hulette, Bradley T. Hyman, Gregory A. Jicha, Lee‐Way Jin, Nancy Johnson, Jason Karlawish, Anna Karydas, Jeffrey Kaye, Ronald Kim, Edward H. Koo, Neil W. Kowall, James J. Lah, Allan I. Levey, Andrew P. Lieberman, Oscar L. López, Wendy J. Mack, Daniel Marson, Frank Martiniuk, Deborah C. Mash, Eliezer Masliah, Wayne C. McCormick, Susan M. McCurry, Andrew McDavid, Ann C. McKee, Marsel Mesulam, Bruce L. Miller ほか 55 名 - Nature Genetics 2011 被引用: 2,014
- World‐Wide FINGERS Network: A global approach to risk reduction and prevention of dementia
著者: Miia Kivipelto, Francesca Mangialasche, Heather M. Snyder, Ricardo Allegri, Sandrine Andrieu, Hidenori Arai, Laura D. Baker, Sylvie Belleville, Henry Brodaty, Sônia Maria Dozzi Brucki, Ismael Luis Calandri, Paulo Caramelli, Christopher Chen, Howard Chertkow, Effie Chew, Seong Hye Choi, Neerja Chowdhary, Lucía Crivelli, Rafael de la Torre, Yifeng Du, Tarun Dua, Mark A. Espeland, Howard Feldman, Maris Hartmanis, Tobias Hartmann, Megan Heffernan, Christiani Jeyakumar Henry, Chang Hyung Hong, Krister Håkansson, Takeshi Iwatsubo, Jee Hyang Jeong, Gustavo Jimenez‐Maggiora, Edward H. Koo, Lenore J. Launer, Jenni Lehtisalo, Francisco Lopera, Pablo Martínez‐Lage, Ralph N. Martins, Lefkos Middleton, José Luís Molinuevo, Manuel Montero‐Odasso, So Young Moon, Kristal Morales‐Pérez, Ricardo Nitríni, Haakon B. Nygaard, Yoo K. Park, Markku Peltonen, Chengxuan Qiu, Yakeel T. Quiroz, Rema Raman, Naren P. Rao, Vijayalakshmi Ravindranath, Anna Rosenberg, Takashi Sakurai, Rosa María Salinas, Philip Scheltens, Gustavo Sevlever, Hilkka Soininen, Ana Luisa Sosa, Cláudia Kimie Suemoto, Mikel Tainta, Lina Velilla, Yongxiang Wang, Rachel A. Whitmer, Xin Xu, Lisa J. Bain, Alina Solomon, Tiia Ngandu, María C. Carrillo - Alzheimer s & Dementia 2020 被引用: 521
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
著者: Mason A. Israel, Shauna H. Yuan, Cédric Bardy, Sol M. Reyna, Yangling Mu, Cheryl Herrera, Michael P. Hefferan, Sebastiaan van Gorp, Kristopher L. Nazor, Francesca S. Boscolo, Christian T. Carson, Louise C. Laurent, Martin Maršala, Fred H. Gage, Anne M. Remes, Edward H. Koo, Lawrence S.B. Goldstein - Nature 2012 被引用: 1,275
- Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
著者: Alan H. Nagahara, David A. Merrill, Giovanni Coppola, Shingo Tsukada, Brock E. Schroeder, Gideon M. Shaked, Ling Wang, Armin Blesch, Albert Kim, J. M. Conner, Edward Rockenstein, Moses V. Chao, Edward H. Koo, Daniel H. Geschwind, Eliezer Masliah, Andrea A. Chiba, Mark H. Tuszynski - Nature Medicine 2009 被引用: 1,037
- Amyloid Precursor Protein Trafficking, Processing, and Function
著者: Gopal Thinakaran, Edward H. Koo - Journal of Biological Chemistry 2008 被引用: 1,113
- Biology and pathophysiology of the amyloid precursor protein
著者: Hui Zheng, Edward H. Koo - Molecular Neurodegeneration 2011 被引用: 346
- Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke
著者: Luting Poh, Sung-Wook Kang, Sang‐Ha Baik, Gavin Ng, David T. She, Priyanka Balaganapathy, S. Thameem Dheen, Tim Magnus, Mathias Gelderblom, Christopher G. Sobey, Edward H. Koo, David Y. Fann, Thiruma V. Arumugam - Brain Behavior and Immunity 2018 被引用: 199
- Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer’s Disease
著者: Goonho Park, Hoang S. Nhan, Sheue-Houy Tyan, Yusuke Kawakatsu, Carolyn Zhang, Mario Navarro, Edward H. Koo - Cell Reports 2020 被引用: 92
- Amyloid β-peptide is produced by cultured cells during normal metabolism
著者: Christian Haass, Michael G. Schlossmacher, Albert Y. Hung, Carmen Vigo‐Pelfrey, Angela Mellon, Beth L. Ostaszewski, Ivan Lieberburg, Edward H. Koo, Dale Schenk, David B. Teplow, Dennis J. Selkoe - Nature 1992 被引用: 1,907
- The amyloid precursor protein: beyond amyloid.
著者: Hui Zheng, Edward H. Koo - Molecular Neurodegeneration 2006 被引用: 393
- Modulation of amyloid β-protein clearance and Alzheimer’s disease susceptibility by the LDL receptor–related protein pathway
著者: David E. Kang, Claus U. Pietrzik, Larry Baum, Nathalie Chevallier, David E. Merriam, Maria Z. Kounnas, Steven L. Wagner, Juan C. Troncoso, Claudia H. Kawas, Robert Katzman, Edward H. Koo - Journal of Clinical Investigation 2000 被引用: 354
- A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
著者: Sascha Weggen, Jason L. Eriksen, Pritam Das, Sarah A. Sagi, Rong Wang, Claus U. Pietrzik, Kirk A. Findlay, Tawnya E. Smith, Michael P. Murphy, Thomas Bülter, David E. Kang, Numa R. Marquez-Sterling, Todd E. Golde, Edward H. Koo - Nature 2001 被引用: 1,388
- The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes
著者: Hoang S. Nhan, Karen Chiang, Edward H. Koo - Acta Neuropathologica 2014 被引用: 240
- Early BDNF Treatment Ameliorates Cell Loss in the Entorhinal Cortex of APP Transgenic Mice
著者: Alan H. Nagahara, Michael Mateling, Imre Kovács, Ling Wang, Simone Eggert, Edward Rockenstein, Edward H. Koo, Eliezer Masliah, Mark H. Tuszynski - Journal of Neuroscience 2013 被引用: 181
- Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments
著者: Christian Haass, Edward H. Koo, Angela Mellon, Albert Y. Hung, Dennis J. Selkoe - Nature 1992 被引用: 899
- Amyloid-β Peptides Interact with Plasma Proteins and Erythrocytes: Implications for Their Quantitation in Plasma
著者: Yu‐Min Kuo, Tyler A. Kokjohn, Walter M. Kalback, Dean C. Luehrs, Douglas Galasko, Nathalie Chevallier, Edward H. Koo, Mark R. Emmerling, Alex E. Roher - Biochemical and Biophysical Research Communications 2000 被引用: 226
- Short Aβ peptides attenuate Aβ42 toxicity in vivo
著者: Brenda D. Moore, Jason Martin, Lorena de Mena, Jonatan Sánchez, Pedro E. Cruz, Carolina Ceballos‐Diaz, Thomas B. Ladd, Yong Ran, Yona Levites, Thomas Kukar, Justin Kurian, Robert McKenna, Edward H. Koo, David Borchelt, Christopher Janus, Diego E. Rincón-Limas, Pedro Fernández-Fúnez, Todd E. Golde - The Journal of Experimental Medicine 2017 被引用: 87
- Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer’s Disease-like Pathology
著者: Jeffrey N. Savas, Yizhi Wang, Laura A. DeNardo, Salvador Martínez‐Bartolomé, Daniel B. McClatchy, Timothy J. Hark, Natalie F. Shanks, Kira Cozzolino, Mathieu Lavallée‐Adam, Samuel N. Smukowski, Sung Kyu Park, Jeffery W. Kelly, Edward H. Koo, Terunaga Nakagawa, Eliezer Masliah, Anirvan Ghosh, John R. Yates - Cell Reports 2017 被引用: 76
- Amyloid diseases: Abnormal protein aggregation in neurodegeneration
著者: Edward H. Koo, Peter T. Lansbury, Jeffery W. Kelly - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 被引用: 697
- Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway
著者: Utpal Das, Lina Wang, Archan Ganguly, Junmi M. Saikia, Steven L. Wagner, Edward H. Koo, Subhojit Roy - Nature Neuroscience 2015 被引用: 194
- γ-Secretase inhibitors and modulators
著者: Todd E. Golde, Edward H. Koo, Kevin M. Felsenstein, Barbara A. Osborne, Lucio Miele - Biochimica et Biophysica Acta (BBA) - Biomembranes 2013 被引用: 277
- Amyloid precursor protein (APP) regulates synaptic structure and function
著者: Sheue-Houy Tyan, Ann Shih, Jessica J. Walsh, Hiroko Maruyama, Floyd Sarsoza, Lawrence Ku, Simone Eggert, Patrick R. Hof, Edward H. Koo, Dara L. Dickstein - Molecular and Cellular Neuroscience 2012 被引用: 185
- SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
著者: Kimberly Ann Chew, Xinyi Xu, Paula Siongco, Steven G Villaraza, April Ka Sin Phua, Zi Xuen Wong, Chooi Yu Chung, Ning Tang, Effie Chew, Christiani Jeyakumar Henry, Edward H. Koo, Christopher Chen - Alzheimer s & Dementia Translational Research & Clinical Interventions 2021 被引用: 26
- Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production
著者: Thomas Kukar, M. Paul Murphy, Jason L. Eriksen, Sarah A. Sagi, Sascha Weggen, Tawnya E. Smith, Thomas B. Ladd, Murad Ali Khan, Rajashaker Kache, J. David Beard, Mark Dodson, Sami L. Merit, Victor Ozols, Panos Z. Anastasiadis, Pritam Das, Abdul H. Fauq, Edward H. Koo, Todd E. Golde - Nature Medicine 2005 被引用: 283
