Dale Schenk
1986–2019 年に発表
- 60
- 論文数
- 28,629
- 被引用数
- 55
- h 指数
- 60
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine78.6%
- Biochemistry, Genetics and Molecular Biology10%
- Neuroscience7.4%
- Computer Science1.5%
- Nursing0.4%
- Immunology and Microbiology0.4%
- その他1.7%
トピック
- Alzheimer's disease research and treatments25.1%
- Computational Drug Discovery Methods6.5%
- Cholinesterase and Neurodegenerative Diseases6.3%
- Parkinson's Disease Mechanisms and Treatments4.6%
- Neuroinflammation and Neurodegeneration Mechanisms4.6%
- Dementia and Cognitive Impairment Research3.6%
- その他49.3%
共著者
- Peter Seubert36
- Dora Games26
- Robin Barbour19
- Ivan Lieberburg13
- Eliezer Masliah10
- Karen Khan9
- Kelly Johnson‐Wood9
- Ruth Motter8
- Frédérique Bard7
- Lisa McConlogue7
- Carmen Vigo‐Pelfrey6
- Dora Kholodenko6
- Ted Yednock6
- Anthony Adame5
- Bradley T. Hyman5
- Dennis J. Selkoe5
- Edward Rockenstein5
- Gergely Tóth5
- Kang Hu5
- Manuel Buttini5
- Michael Lee5
- Brian Spencer4
- Christopher M. Dobson4
- Ferdie Soriano4
全論文
- Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease
著者: John P. Anderson, Donald E. Walker, Jason Goldstein, Rian de Laat, Kelly Banducci, Russell Caccavello, Robin Barbour, Jiping Huang, Kristin Kling, Michael Lee, Linnea Diep, Pamela S. Keim, Xiaofeng Shen, Tim Chataway, Michael G. Schlossmacher, Peter Seubert, Dale Schenk, Sukanto Sinha, Wei Gai, Tamie J. Chilcote - Journal of Biological Chemistry 2006 被引用: 1,447
- Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
著者: Dale Schenk, Robin Barbour, Whitney Dunn, Grace Gordon, Henry Grajeda, Teresa Guido, Kang Hu, Jiping Huang, Kelly Johnson‐Wood, Karen Khan, Dora Kholodenko, Mike Lee, Zhenmei Liao, Ivan Lieberburg, Ruth Motter, Linda Mutter, Ferdie Soriano, George M. Shopp, Nicki Vasquez, Christopher Vandevert, Shannan Walker, Mark Wogulis, Ted Yednock, Dora Games, Peter Seubert - Nature 1999 被引用: 3,158
- Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
著者: Dora Games, David S. Adams, Ree Alessandrini, Robin Barbour, Patricia Borthelette, Catherine Blackwell, Tony Carr, James A. Clemens, Thomas Donaldson, Frances P. Gillespie, Terry Guido, S. Hagopian, Kelly Johnson‐Wood, Karen Khan, Mike Lee, Paul J. Leibowitz, Ivan Lieberburg, Sheila P. Little, Eliezer Masliah, Lisa McConlogue, Martin Montoya‐Zavala, Lennart Mucke, Lisa Paganini, Elizabeth Penniman, Mike Power, Dale Schenk, Peter Seubert, Ben Snyder, Ferdie Soriano, Hua Tan, James Vitale, Sam Wadsworth, Ben Wolozin, Jun Zhao - Nature 1995 被引用: 2,509
- Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
著者: Frédérique Bard, Catherine Cannon, Robin Barbour, Rae-Lyn Burke, Dora Games, Henry Grajeda, Teresa Guido, Kang Hu, Jiping Huang, Kelly Johnson‐Wood, Karen Khan, Dora Kholodenko, Mike Lee, Ivan Lieberburg, Ruth Motter, Minh Dang Nguyen, Ferdie Soriano, Nicki Vasquez, Kim Altman Weiss, Brent Welch, Peter Seubert, Dale Schenk, Ted Yednock - Nature Medicine 2000 被引用: 2,006
- A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
著者: Stephen Salloway, Reisa A. Sperling, S. Gilman, Nick C. Fox, Kaj Blennow, Murray A. Raskind, Marwan N. Sabbagh, Lawrence S. Honig, Rachelle S. Doody, Christopher H. van Dyck, Ruth A. Mulnard, Jerome Barakos, K. M. Gregg, E. Liu, Ivan Lieberburg, Dale Schenk, Ronald S. Black, Michael Grundman - Neurology 2009 被引用: 739
- Reducing C-Terminal-Truncated Alpha-Synuclein by Immunotherapy Attenuates Neurodegeneration and Propagation in Parkinson's Disease-Like Models
著者: Dora Games, Elvira Valera, Brian Spencer, Edward Rockenstein, Michael Mante, Anthony Adame, Christina Patrick, Kiren Ubhi, Silke Nuber, Patricia Sacayon, Wagner Zago, Peter Seubert, Robin Barbour, Dale Schenk, Eliezer Masliah - Journal of Neuroscience 2014 被引用: 320
- Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease
著者: Eliezer Masliah, Edward Rockenstein, Michael Mante, Leslie Crews, Brian Spencer, Anthony Adame, Christina Patrick, Margarita Trejo, Kiren Ubhi, Troy T. Rohn, Sarah Mueller-Steiner, Peter Seubert, Robin Barbour, Lisa McConlogue, Manuel Buttini, Dora Games, Dale Schenk - PLoS ONE 2011 被引用: 422
- The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway
著者: Christian Haass, Cynthia A. Lemere, Anja Capell, Martin Citron, Peter Seubert, Dale Schenk, Lars Lannfelt, Dennis J. Selkoe - Nature Medicine 1995 被引用: 581
- Reduction of β‐amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease
著者: Ruth Motter, Carmen Vigo‐Pelfrey, Dora Kholodenko, Robin Barbour, Kelly Johnson‐Wood, Douglas Galasko, L. Chang, Bruce L. Miller, Christopher M. Clark, R. Green, Darin E. Olson, Paula C. Southwick, R. Wolfert, B.S. Alelia E. Munroe, Ivan Lieberburg, Peter Seubert, Dale Schenk - Annals of Neurology 1995 被引用: 694
- Amyloid β-peptide is produced by cultured cells during normal metabolism
著者: Christian Haass, Michael G. Schlossmacher, Albert Y. Hung, Carmen Vigo‐Pelfrey, Angela Mellon, Beth L. Ostaszewski, Ivan Lieberburg, Edward H. Koo, Dale Schenk, David B. Teplow, Dennis J. Selkoe - Nature 1992 被引用: 1,907
- Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
著者: Peter Seubert, Carmen Vigo‐Pelfrey, Fred Esch, Michael Lee, Harry F. Dovey, D. H. S. Davis, Sukanto Sinha, Michael Schiossmacher, Justine Whaley, Cathy Swindlehurst, Robert McCormack, Robert L. Wolfert, Dennis J. Selkoe, Ivan Lieberburg, Dale Schenk - Nature 1992 被引用: 1,740
- Purification and cloning of amyloid precursor protein β-secretase from human brain
著者: Sukanto Sinha, John P. Anderson, Robin Barbour, Guriqbal S. Basi, Russell Caccavello, David L. Davis, Minhtam Doan, Harry F. Dovey, Normand L. Frigon, Jin Hong, Kirsten Jacobson-Croak, Nancy Jewett, Pamela S. Keim, Jeroen Knops, Ivan Lieberburg, Michael D. Power, Hua Tan, Gwen Tatsuno, Jay S. Tung, Dale Schenk, Peter Seubert, Susanna Suomensaari, Shuwen Wang, Donald E. Walker, Jun Zhao, Lisa McConlogue, Varghese John - Nature 1999 被引用: 1,598
- Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
著者: Martin Citron, David Westaway, Weiming Xia, George A. Carlson, Thekla S. Diehl, Georges Lévesque, Kelly Johnson‐Wood, Michael Lee, Peter Seubert, Angela Davis, Dora Kholodenko, Ruth Motter, Robin Sherrington, Billie J. Perry, Hong Yao, Robert Strome, Ivan Lieberburg, Johanna M. Rommens, Soyeon Kim, Dale Schenk, Paul Fraser, Peter St George‐Hyslop, Dennis J. Selkoe - Nature Medicine 1997 被引用: 1,267
- 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study
著者: Juha O. Rinne, David J. Brooks, Martin N. Rossor, Nick C. Fox, Roger Bullock, William E. Klunk, Chester A. Mathis, Kaj Blennow, Jerome Barakos, Aren Okello, Sofia Rodriguez Martinez de Liano, Enchi Liu, Martin Koller, Keith M. Gregg, Dale Schenk, Ronald S. Black, Michael Grundman - The Lancet Neurology 2010 被引用: 695
- Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease
著者: Gergely Tóth, Shyra J. Gardai, Wagner Zago, Carlos W. Bertoncini, Nunilo Cremades, Susan L. Roy, Mitali A. Tambe, Jean‐Christophe Rochet, Céline Galvagnion, Gaia Skibinski, Steven Finkbeiner, Michael P. Bova, Karin Regnström, San-San Chiou, Jennifer Johnston, Kari Callaway, John P. Anderson, Michael F. Jobling, Alexander K. Buell, Ted Yednock, Tuomas P. J. Knowles, Michele Vendruscolo, John Christodoulou, Christopher M. Dobson, Dale Schenk, Lisa McConlogue - PLoS ONE 2014 被引用: 152
- Amyloid precursor protein processing and Aβ 42 deposition in a transgenic mouse model of Alzheimer disease
著者: Kelly Johnson‐Wood, M. Lee, Ruth Motter, Kang Hu, Grace Gordon, Robin Barbour, Karen Khan, Marcia N. Gordon, Hua Tan, Dora Games, Ivan Lieberburg, Dale Schenk, Peter Seubert, Lisa McConlogue - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 被引用: 658
- The Role of Biomarkers in Clinical Trials for Alzheimer Disease
著者: Leon J. Thal, Kejal Kantarci, Eric M. Reiman, William E. Klunk, Michael W. Weiner, Henrik Zetterberg, Douglas Galasko, Domenico Praticò, Sue Griffin, Dale Schenk, Eric Siemers - Alzheimer Disease & Associated Disorders 2006 被引用: 231
- Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model
著者: John F. Reilly, Dora Games, Russell E. Rydel, Stephen B. Freedman, Dale Schenk, Warren G. Young, John H. Morrison, Floyd E. Bloom - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 被引用: 175
- High Cerebrospinal Fluid Tau and Low Amyloid β42 Levels in the Clinical Diagnosis of Alzheimer Disease and Relation to Apolipoprotein E Genotype
著者: Douglas Galasko, L. Chang, Ruth Motter, Christopher M. Clark, Jeffrey Kaye, David S. Knopman, Ronald G. Thomas, Dora Kholodenko, Dale Schenk, Ivan Lieberburg, Bruce L. Miller, R. Green, R. Basherad, L. Kertiles, Michael A. Boss, Peter Seubert - Archives of Neurology 1998 被引用: 446
- Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology
著者: Frédérique Bard, Robin Barbour, Catherine Cannon, Robert Carretto, Michael Fox, Dora Games, Teresa Guido, Kathleen Hoenow, Kang Hu, Kelly Johnson‐Wood, Karen Khan, Dora Kholodenko, Celeste Lee, Mike Lee, Ruth Motter, Minh Dang Nguyen, Amanda Reed, Dale Schenk, Pearl Tang, Nicki Vasquez, Peter Seubert, Ted Yednock - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 被引用: 407
- Aβ Species Removal After Aβ42Immunization
著者: James A. R. Nicoll, Edward Barton, Delphine Boche, J. W. Neal, Isidró Ferrer, Petrina Thompson, Christina Vlachouli, David G. Wilkinson, Antony Bayer, Dora Games, Peter Seubert, Dale Schenk, Clive Holmes - Journal of Neuropathology & Experimental Neurology 2006 被引用: 266
- Morphological Characterization of Thioflavin-S-Positive Amyloid Plaques in Transgenic Alzheimer Mice and Effect of Passive Aβ Immunotherapy on Their Clearance
著者: Thierry Bussière, Frédérique Bard, Robin Barbour, Henry Grajeda, Terry Guido, Karen Khan, Dale Schenk, Dora Games, Peter Seubert, Manuel Buttini - American Journal Of Pathology 2004 被引用: 173
- Immunotherapy Reduces Vascular Amyloid- in PDAPP Mice
著者: Sally Schroeter, Karen Khan, Robin Barbour, Minh L. Doan, M. Chen, Terry Guido, Deborah R. Gill, G.S. Basi, Dale Schenk, Peter Seubert, Dora Games - Journal of Neuroscience 2008 被引用: 145
- Aβ Immunotherapy: Intracerebral Sequestration of Aβ by an Anti-Aβ Monoclonal Antibody 266 with High Affinity to Soluble Aβ
著者: Kaoru Yamada, Chiori Yabuki, Peter Seubert, Dale Schenk, Yukiko Hori, Sumio Ohtsuki, Tetsuya Terasaki, Tadafumi Hashimoto, Takeshi Iwatsubo - Journal of Neuroscience 2009 被引用: 117
