Ira Pastan
1960–2024 年に発表
- 453
- 論文数
- 87,307
- 被引用数
- 167
- h 指数
- 451
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine50.3%
- Biochemistry, Genetics and Molecular Biology32.7%
- Immunology and Microbiology8.2%
- Neuroscience3%
- Materials Science1.4%
- Agricultural and Biological Sciences1.1%
- その他3.3%
トピック
- Drug Transport and Resistance Mechanisms5.5%
- Monoclonal and Polyclonal Antibodies Research3.1%
- CAR-T cell therapy research3%
- Virus-based gene therapy research2%
- Glycosylation and Glycoproteins Research1.8%
- Pharmacological Effects and Toxicity Studies1.7%
- その他82.9%
共著者
- Michael M. Gottesman71
- Mark C. Willingham69
- Robert J. Kreitman46
- Raffit Hassan35
- David Fitzgerald24
- David J. FitzGerald23
- Glenn Merlino22
- Tapan K. Bera22
- Masanori Onda20
- Ulrich Brinkmann19
- Byungkook Lee17
- George S. Johnson17
- Benoît De Crombrugghe16
- Vijay K. Chaudhary16
- M M Gottesman14
- Mitchell Ho13
- Richard Beers13
- Robert L. Perlman13
- Antonio Tito Fojo11
- Kazumitsu Ueda11
- Kenneth M. Yamada11
- Maria Gallo11
- Nancy Richert11
- Shigetada Nakanishi11
全論文
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
著者: Carmine Carpenito, Michael C. Milone, Raffit Hassan, Jacqueline C. Simonet, Mehdi Lakhal, Megan M. Suhoski, Angel Varela‐Rohena, Kathleen M. Haines, Daniel F. Heitjan, Steven Μ. Albelda, Richard G. Carroll, James L. Riley, Ira Pastan, Carl H. June - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 被引用: 889
- Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma
著者: Nadja Müller, Susanne Michen, Stefanie Tietze, Katrin Töpfer, Alexander Schulte, Katrin Lamszus, Marc Schmitz, Gabriele Schackert, Ira Pastan, Achim Temme - Journal of Immunotherapy 2015 被引用: 248
- Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia
著者: Waleed Haso, Daniel W. Lee, Nirali N. Shah, Maryalice Stetler‐Stevenson, Constance M. Yuan, Ira Pastan, Dimiter S. Dimitrov, Richard A. Morgan, David J. FitzGerald, David M. Barrett, Alan S. Wayne, Crystal L. Mackall, Rimas J. Orentas - Blood 2012 被引用: 583
- Mesothelin Immunotherapy for Cancer: Ready for Prime Time?
著者: Raffit Hassan, Anish Thomas, Christine Alewine, Dung T. Le, Elizabeth M. Jaffee, Ira Pastan - Journal of Clinical Oncology 2016 被引用: 321
- Discovery of Mesothelin and Exploiting It as a Target for Immunotherapy
著者: Ira Pastan, Raffit Hassan - Cancer Research 2014 被引用: 250
- Moxetumomab pasudotox in relapsed/refractory hairy cell leukemia
著者: Robert J. Kreitman, Claire Dearden, Pier Luigi Zinzani, Julio Delgado, Lionel Karlin, Tadeusz Robak, Douglas E. Gladstone, Philipp le Coutre, Sascha Dietrich, Mirjana Gotić, Loree Larratt, Fritz Offner, Gary J. Schiller, Ronan Swords, Larry Bacon, Monica Bocchia, Krimo Bouabdallah, Dimitri Breems, Agostino Cortelezzi, Shira Dinner, Michael Doubek, Bjørn Tore Gjertsen, Marco Gobbi, Andrzej Hellmann, Stéphane Leprêtre, Frédéric Maloisel, Farhad Ravandi, Philippe Rousselot, Mathias Rummel, Tanya Siddiqi, Tamar Tadmor, Xavier Troussard, Cecilia Arana Yi, Giuseppe Saglio, Gail J. Roboz, Kemal Balic, Nathan Standifer, Peng He, Shannon Marshall, Wyndham H. Wilson, Ira Pastan, Nai-Shun Yao, Francis J. Giles - Leukemia 2018 被引用: 247
- Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors
著者: Jennifer A. A. Gubbels, Jennifer A. Belisle, Masanori Onda, Claudine Rancourt, Martine Migneault, Mitchell Ho, Tapan K. Bera, Joseph P. Connor, Bangalore K. Sathyanarayana, Byungkook Lee, Ira Pastan, Manish S. Patankar - Molecular Cancer 2006 被引用: 443
- BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER
著者: Suresh V. Ambudkar, Saibal Dey, Christine A. Hrycyna, Murali Ramachandra, Ira Pastan, Michael M. Gottesman - The Annual Review of Pharmacology and Toxicology 1999 被引用: 2,062
- Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.
著者: King‐Jen Chang, Ira Pastan - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 被引用: 742
- Mesothelin
著者: Raffit Hassan, Tapan K. Bera, Ira Pastan - Clinical Cancer Research 2004 被引用: 439
- Depletion of regulatory T cells in tumors with an anti-CD25 immunotoxin induces CD8 T cell-mediated systemic antitumor immunity
著者: Masanori Onda, Kazuto Kobayashi, Ira Pastan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 被引用: 109
- Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin
著者: Xiufen Liu, Masanori Onda, Nathan Watson, Raffit Hassan, Mitchell Ho, Tapan K. Bera, Junxia Wei, Anirban Chakraborty, Richard Beers, Qi Zhou, Asif Shajahan, Parastoo Azadi, Jingyu Zhan, Di Xia, Ira Pastan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 被引用: 49
- Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors
著者: Sakshi Tomar, Jingli Zhang, Manakamana Khanal, Jessica Hong, Abhilash Venugopalan, Qun Jiang, Manjistha Sengupta, Markku Miettinen, Nan Li, Ira Pastan, Mitchell Ho, Raffit Hassan - Molecular Cancer Therapeutics 2022 被引用: 46
- α-Galactosidase A deficient mice: A model of Fabry disease
著者: Toshio Ohshima, Gary J. Murray, William D. Swaim, Glenn Longenecker, Jane M. Quirk, Carol Cardarelli, Yoshikazu Sugimoto, Ira Pastan, Michael M. Gottesman, Roscoe O. Brady, Ashok B. Kulkarni - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 被引用: 368
- The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) Gene
著者: Michael M. Gottesman, Ira Pastan - JNCI Journal of the National Cancer Institute 2015 被引用: 147
- Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial
著者: the Study 1053 investigators, Robert J. Kreitman, Claire Dearden, Pier Luigi Zinzani, Julio Delgado, Tadeusz Robak, Philipp D. le Coutre, Bjørn Tore Gjertsen, Xavier Troussard, Gail J. Roboz, Lionel Karlin, Douglas E. Gladstone, Nataliya Kuptsova‐Clarkson, Shiyao Liu, Priti Patel, Federico Rotolo, Emmanuel Mitry, Ira Pastan, Francis J. Giles - Journal of Hematology & Oncology 2021 被引用: 85
- Phase I Study of SS1P, a Recombinant Anti-Mesothelin Immunotoxin Given as a Bolus I.V. Infusion to Patients with Mesothelin-Expressing Mesothelioma, Ovarian, and Pancreatic Cancers
著者: Raffit Hassan, Susie Bullock, Ahalya Premkumar, Robert J. Kreitman, Hedy L. Kindler, Mark C. Willingham, Ira Pastan - Clinical Cancer Research 2007 被引用: 381
- Characterization of CD22 expression in acute lymphoblastic leukemia
著者: Nirali N. Shah, Maryalice Stetler Stevenson, Constance M. Yuan, Kelly Richards, Cindy Delbrook, Robert J. Kreitman, Ira Pastan, Alan S. Wayne - Pediatric Blood & Cancer 2015 被引用: 175
- 3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors
著者: Zhongwei Li, Toshikazu Araoka, Jun Wu, Hsin-Kai Liao, Mo Li, Marta Lazo-Rodríguez, Bing Zhou, Yinghui Sui, Min-Zu Wu, Isao Tamura, Yun Xia, Ergin Beyret, Taiji Matsusaka, Ira Pastan, Concepción Rodrı́guez Esteban, Isabel Guillén, Pedro Guillén, Josep M. Campistol, Juan Carlos Izpisúa Belmonte - Cell stem cell 2016 被引用: 182
- Antibody Fusion Proteins: Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox
著者: Robert J. Kreitman, Ira Pastan - Clinical Cancer Research 2011 被引用: 231
- Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models
著者: Scott Parker, Charlotte McDowall, Luis Sánchez-Pérez, Cristina Osorio, Patrick C. Duncker, Aaron Briley, Adam M. Swartz, James E. Herndon, Yen‐Rei Yu, Roger E. McLendon, Thomas F. Tedder, Annick Desjardins, David M. Ashley, Michael D. Gunn, David S. Enterline, David A. Knorr, Ira Pastan, Smita K. Nair, Darell D. Bigner, Vidya Chandramohan - Science Translational Medicine 2023 被引用: 30
- Anti-mesothelin immunotoxin induces mesothelioma eradication, anti-tumor immunity, and the development of tertiary lymphoid structures
著者: Wenlong Liu, Chin‐Hsien Tai, Xiufen Liu, Ira Pastan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 被引用: 21
- Mesothelin Is Not Required for Normal Mouse Development or Reproduction
著者: Tapan K. Bera, Ira Pastan - Molecular and Cellular Biology 2000 被引用: 254
- Distinct Roles of Segregated Transmission of the Septo-Habenular Pathway in Anxiety and Fear
著者: Takashi Yamaguchi, Teruko Danjo, Ira Pastan, Takatoshi Hikida, Shigetada Nakanishi - Neuron 2013 被引用: 194
