James L. Riley
1994–2025 年に発表
- 95
- 論文数
- 24,879
- 被引用数
- 77
- h 指数
- 90
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine51.7%
- Immunology and Microbiology31.2%
- Biochemistry, Genetics and Molecular Biology15%
- Neuroscience0.9%
- Engineering0.4%
- Agricultural and Biological Sciences0.2%
- その他0.6%
トピック
- Immune Cell Function and Interaction13.3%
- CAR-T cell therapy research11.7%
- Immunotherapy and Immune Responses8%
- T-cell and B-cell Immunology7.7%
- Cancer Immunotherapy and Biomarkers7.6%
- Virus-based gene therapy research3.2%
- その他48.5%
共著者
- Carl H. June47
- Bruce L. Levine17
- Richard G. Carroll16
- Bruce R. Blazar11
- Colby R. Maldini8
- Tatiana N. Golovina8
- Angel Varela‐Rohena7
- Carmine Carpenito7
- Michael C. Milone7
- Gabriela Plesa6
- Hong Kong6
- Jeffrey S. Miller6
- Keli L. Hippen6
- Megan M. Suhoski6
- Gavin I. Ellis5
- Jens M. Chemnitz5
- Max W. Richardson5
- Michael C. Holmes5
- Richard V. Parry5
- Frederic D. Bushman4
- Gary Lee4
- Gloria B. Kim4
- Jeremy M. Boss4
- Jianbin Wang4
全論文
- PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial
著者: Vivek Narayan, Julie S. Barber-Rotenberg, In-Young Jung, Simon F. Lacey, Andrew J. Rech, Megan M. Davis, Wei‐Ting Hwang, Priti Lal, Erica L. Carpenter, Shannon L. Maude, Gabriela Plesa, Neha Vapiwala, Anne Chew, Michael Moniak, Ronnie Sebro, Michael D. Farwell, Amy Marshall, Joan Gilmore, Lester Lledo, Karen Dengel, S. Church, Tyler Hether, Jun Xu, Mercy Gohil, Thomas H. Buckingham, Stephanie S. Yee, Vanessa Gonzalez, Irina Kulikovskaya, Fang Chen, Lifeng Tian, Kyle Tien, Whitney L. Gladney, Christopher L. Nobles, Hayley E. Raymond, Prostate Cancer Cellular Therapy Program Investigators, Diane Frazee, Mary Truran, Elizabeth Veloso, Holly McConville, Jonathan Aguedelo, Samantha Hower, Sophia Ngo, Julie K. Jadlowsky, J. Joseph Melenhorst, Aoife M. Roche, J.K. Everett, Minnal Gupta, Farzana Nazimuddin, Chelsie Bartoszek, Natalka Koterba, Rachael Reynolds, Farris Ellington, Christopher C. Kloss, Ji‐Hyun Lee, Yangbing Zhao, John Scholler, James L. Riley, Christina Bailey, Andrew J. P. White, Briana M. Hudson, Pearl Chang, Marcela V. Maus, Bruce L. Levine, Elizabeth O. Hexner, Donald L. Siegel, Frederic D. Bushman, Carl H. June, Joseph A. Fraietta, Naomi B. Haas - Nature Medicine 2022 被引用: 500
- CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms
著者: Richard V. Parry, Jens M. Chemnitz, Kenneth A. Frauwirth, Anthony R. Lanfranco, Inbal Braunstein, Sumire Kobayashi, Peter S. Linsley, Craig B. Thompson, James L. Riley - Molecular and Cellular Biology 2005 被引用: 1,902
- The CD28 Signaling Pathway Regulates Glucose Metabolism
著者: Kenneth A. Frauwirth, James L. Riley, Marian H. Harris, Richard V. Parry, Jeffrey C. Rathmell, David R. Plas, Rebecca Elstrom, Carl H. June, Craig B. Thompson - Immunity 2002 被引用: 1,441
- Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo
著者: Michael C. Milone, Jonathan D. Fish, Carmine Carpenito, Richard G. Carroll, Gwendolyn K. Binder, David T. Teachey, Minu Samanta, Mehdi Lakhal, Brian Gloss, Gwenn Danet-Desnoyers, Dario Campana, James L. Riley, Stephan A. Grupp, Carl H. June - Molecular Therapy 2009 被引用: 1,189
- SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation
著者: Jens M. Chemnitz, Richard V. Parry, Kim E. Nichols, Carl H. June, James L. Riley - The Journal of Immunology 2004 被引用: 1,231
- Role of PD-1 during effector CD8 T cell differentiation
著者: Eunseon Ahn, Koichi Araki, Masao Hashimoto, Weiyan Li, James L. Riley, Jeanne Cheung, Arlene H. Sharpe, Gordon J. Freeman, Bryan Irving, Rafi Ahmed - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 被引用: 482
- Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells
著者: Brian Cameron, Andrew B. Gerry, Joseph Dukes, Jane Harper, Vivekanandan Kannan, Frayne Bianchi, Francis Grand, Joanna E. Brewer, Minnal Gupta, Gabriela Plesa, Giovanna Bossi, Annelise Vuidepot, Alex S. Powlesland, Alison Legg, Katherine J. Adams, Alan Bennett, Nicholas J. Pumphrey, Daniel Williams, Gwendolyn Binder-Scholl, Irina Kulikovskaya, Bruce L. Levine, James L. Riley, Angel Varela‐Rohena, Edward A. Stadtmauer, Aaron P. Rapoport, Gerald P. Linette, Carl H. June, Namir J. Hassan, Michael Kalos, Bent K. Jakobsen - Science Translational Medicine 2013 被引用: 677
- PD‐1 signaling in primary T cells
著者: James L. Riley - Immunological Reviews 2009 被引用: 769
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
著者: Carmine Carpenito, Michael C. Milone, Raffit Hassan, Jacqueline C. Simonet, Mehdi Lakhal, Megan M. Suhoski, Angel Varela‐Rohena, Kathleen M. Haines, Daniel F. Heitjan, Steven Μ. Albelda, Richard G. Carroll, James L. Riley, Ira Pastan, Carl H. June - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 被引用: 889
- Genetic engineering of T cells for immunotherapy
著者: Gavin I. Ellis, Neil C. Sheppard, James L. Riley - Nature Reviews Genetics 2021 被引用: 159
- Chronic Virus Infection Enforces Demethylation of the Locus that Encodes PD-1 in Antigen-Specific CD8+ T Cells
著者: Ben Youngblood, Kenneth J. Oestreich, Sang‐Jun Ha, Jaikumar Duraiswamy, Rama Akondy, Erin E. West, Zhengyu Wei, Peiyuan Lu, James W. Austin, James L. Riley, Jeremy M. Boss, Rafi Ahmed - Immunity 2011 被引用: 408
- Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo
著者: Colby R. Maldini, Daniel T. Claiborne, Ken Okawa, Tao Chen, Derrick L. Dopkin, Xiaochuan Shan, Karen A. Power, Radiana Trifonova, Katharine L. Krupp, Meredith Phelps, Vladimir Vrbanac, Serah Tanno, Timothy Bateson, George J. Leslie, James A. Hoxie, Christian L. Boutwell, James L. Riley, Todd M. Allen - Nature Medicine 2020 被引用: 126
- The PDL1-PD1 Axis Converts Human T H 1 Cells into Regulatory T Cells
著者: Shoba Amarnath, Courtney W. Mangus, James C.M. Wang, Fang Wei, Alice He, Veena Kapoor, Jason Foley, Paul R. Massey, Tania C. Felizardo, James L. Riley, Bruce L. Levine, Carl H. June, Jeffrey A. Medin, Daniel H. Fowler - Science Translational Medicine 2011 被引用: 440
- Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells
著者: John Scholler, Troy Brady, Gwendolyn Binder-Scholl, Wei‐Ting Hwang, Gabriela Plesa, Kristen Hege, Ashley N. Vogel, Michael Kalos, James L. Riley, Steven G. Deeks, Ronald T. Mitsuyasu, Wendy B. Bernstein, Naomi Aronson, Bruce L. Levine, Frederic D. Bushman, Carl H. June - Science Translational Medicine 2012 被引用: 647
- Expression of a Functional CCR2 Receptor Enhances Tumor Localization and Tumor Eradication by Retargeted Human T cells Expressing a Mesothelin-Specific Chimeric Antibody Receptor
著者: Edmund K. Moon, Carmine Carpenito, Jing Sun, Liang‐Chuan S. Wang, Veena Kapoor, Jarrod D. Predina, Daniel J. Powell, James L. Riley, Carl H. June, Steven Μ. Albelda - Clinical Cancer Research 2011 被引用: 521
- CAR T cells for infection, autoimmunity and allotransplantation
著者: Colby R. Maldini, Gavin I. Ellis, James L. Riley - Nature reviews. Immunology 2018 被引用: 231
- Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors
著者: Edmund K. Moon, Liang-Chuan Wang, Douglas V. Dolfi, Caleph B. Wilson, Raghuveer Ranganathan, Jing Sun, Veena Kapoor, John Scholler, Ellen Puré, Michael C. Milone, Carl H. June, James L. Riley, E. John Wherry, Steven Μ. Albelda - Clinical Cancer Research 2014 被引用: 410
- Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect
著者: Claudio G. Brunstein, Jeffrey S. Miller, David H. McKenna, Keli L. Hippen, Todd E. DeFor, Darin Sumstad, Julie Curtsinger, Michael R. Verneris, Margaret L. MacMillan, Bruce L. Levine, James L. Riley, Carl H. June, Chap T. Le, Daniel J. Weisdorf, Philip B. McGlave, Bruce R. Blazar, John E. Wagner - Blood 2015 被引用: 401
- CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication
著者: Pablo Tebas, Julie K. Jadlowsky, Pamela A. Shaw, Lifeng Tian, Erin Esparza, Andrea Brennan, Su Kyung Kim, Soe Yu Naing, Max W. Richardson, Ashley N. Vogel, Colby R. Maldini, Hong Kong, Xiaojun Liu, Simon F. Lacey, Anya M. Bauer, Felicity Mampe, Lee P. Richman, Gary Lee, Dale Ando, Bruce L. Levine, David L. Porter, Yangbing Zhao, Don L. Siegel, Katharine J. Bar, Carl H. June, James L. Riley - Journal of Clinical Investigation 2021 被引用: 98
- CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients
著者: Andrew J. Rech, Rosemarie Mick, Sunil Martin, Adri Recio, Nicole A. Aqui, Daniel J. Powell, Theresa A. Colligon, Jennifer A. Trosko, Leah I. Leinbach, Charles H. Pletcher, Carol Tweed, Angela DeMichele, Kevin R. Fox, Susan M. Domchek, James L. Riley, Robert H. Vonderheide - Science Translational Medicine 2012 被引用: 328
- Lack of immunoediting in murine pancreatic cancer reversed with neoantigen
著者: Rebecca A. Evans, Mark S. Diamond, Andrew J. Rech, Timothy Chao, Max W. Richardson, Jeffrey Lin, David L. Bajor, Katelyn T. Byrne, Ben Z. Stanger, James L. Riley, Nune Markosyan, Rafael Winograd, Robert H. Vonderheide - JCI Insight 2016 被引用: 181
- Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
著者: Elena Pérez, Jianbin Wang, Jeffrey C. Miller, Yann Jouvenot, Kenneth A Kim, Olga Liu, Nathaniel Wang, Gary Lee, Victor V. Bartsevich, Ya-Li Lee, Dmitry Guschin, Igor Rupniewski, Adam James Waite, Carmine Carpenito, Richard G. Carroll, Jordan S. Orange, Fyodor D. Urnov, Edward J. Rebar, Dale Ando, Philip D. Gregory, James L. Riley, Michael C. Holmes, Carl H. June - Nature Biotechnology 2008 被引用: 999
- Strength of PD-1 signaling differentially affects T-cell effector functions
著者: Fang Wei, Zhong Shi, Zhengyu Ma, Hong Kong, Andrew Medvec, Rafi Ahmed, Gordon J. Freeman, Michelle Krogsgaard, James L. Riley - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 被引用: 300
- Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies
著者: Julie K. Jadlowsky, Elizabeth O. Hexner, Amy Marshall, Stephan A. Grupp, Noelle V. Frey, James L. Riley, Elizabeth Veloso, Holly McConville, Walter Rogal, Cory Czuczman, Wei‐Ting Hwang, Yimei Li, Rachel Leskowitz, Olivia Farrelly, Jayashree Karar, Shannon Christensen, Julie S. Barber-Rotenberg, Avery L. Gaymon, Naomi Aronson, Wendy Bernstein, J. Joseph Melenhorst, Aoife M. Roche, J.K. Everett, Sonja A. Zolnoski, Alexander McFarland, Shantan Reddy, Angelina Petrichenko, Emma J. Cook, Carole Lee, Vanessa Gonzalez, Kathleen A. Alexander, Irina Kulikovskaya, Ángel Ramírez-Fernández, Janna Minehart, Marco Ruella, Saar Gill, Stephen J. Schuster, Adam D. Cohen, Alfred L. Garfall, Payal D. Shah, David L. Porter, Shannon L. Maude, Bruce L. Levine, Don L. Siegel, Anne Chew, S.J. McKenna, Lester Lledo, Megan M. Davis, Gabriela Plesa, Friederike Herbst, Edward A. Stadtmauer, Pablo Tebas, Amanda M. DiNofia, A. Haas, Naomi B. Haas, Regina M. Myers, Donald M. O’Rourke, Jakub Svoboda, János L. Tanyi, Richard Aplenc, Jeffrey M. Jacobson, Andrew H. Ko, Roger B. Cohen, Carl H. June, Frederic D. Bushman, Joseph A. Fraietta - Nature Medicine 2025 被引用: 71
