John D. Isaacs
1992–2025 年に発表
- 155
- 論文数
- 19,724
- 被引用数
- 83
- h 指数
- 146
- i10 指数
被引用数
引用元
国・地域
機関
- Inserm0.9%
- University of Leeds0.7%
- Harvard University0.6%
- Newcastle University0.6%
- University of Manchester0.6%
- University of Oxford0.5%
- その他96.1%
分野
- Medicine63.9%
- Immunology and Microbiology17.9%
- Biochemistry, Genetics and Molecular Biology12.9%
- Neuroscience1.1%
- Pharmacology, Toxicology and Pharmaceutics1%
- Engineering0.5%
- その他2.7%
トピック
- Rheumatoid Arthritis Research and Therapies10.5%
- Systemic Lupus Erythematosus Research4.4%
- T-cell and B-cell Immunology4.3%
- Autoimmune and Inflammatory Disorders Research3.6%
- Spondyloarthritis Studies and Treatments3.5%
- Immune Cell Function and Interaction3.3%
- その他70.4%
共著者
- Arthur G. Pratt37
- Paul Emery24
- Ann W Morgan22
- Amy E. Anderson20
- Iain B. McInnes19
- Anne Barton18
- Catharien M. U. Hilkens18
- Anthony G. Wilson17
- Kimme L Hyrich17
- Darren Plant14
- Maya H Buch12
- Andrew Filer11
- Christopher D. Buckley9
- Dennis Lendrem9
- Faye A. H. Cooles8
- Gerd R Burmester8
- Herman Waldmann8
- Julie Diboll8
- Costantino Pitzalis7
- Dennis McGonagle7
- G Hale7
- Josef S Smolen7
- Kevin Winthrop7
- Nisha Nair7
全論文
- Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
著者: Felice Rivellese, Anna E. A. Surace, Katriona Goldmann, Elisabetta Sciacca, Cankut Çubuk, Giovanni Giorli, Christopher R. John, Alessandra Nerviani, Liliane Fossati‐Jimack, Georgina Thorborn, Manzoor Ahmed, Edoardo Prediletto, S. Church, Briana M. Hudson, Sarah Warren, Paul McKeigue, Frances Humby, Michele Bombardieri, Michael R. Barnes, Myles Lewis, Costantino Pitzalis, the R4RA collaborative group, Felice Rivellese, Giovanni Giorli, Alessandra Nerviani, Liliane Fossati‐Jimack, Georgina Thorborn, Frances Humby, Michele Bombardieri, Myles Lewis, Patrick Durez, Maya H Buch, Hasan Rizvi, Arti Mahto, Carlomaurizio Montecucco, Bernard Lauwerys, Nora Ng, Pauline Ho, Vasco C. Romão, João Eurico Fonseca, Patrick Verschueren, Stephen Kelly, Pier Paolo Sainaghi, Nagui Gendi, Bhaskar DasGupta, Alberto Cauli, Piero Reynolds, Juan D. Cañete, Julio Ramírez, Raquel Celis, Robert J. Moots, Peter C. Taylor, C J Edwards, John D. Isaacs, Peter Sasieni, Ernest Choy, Charlotte Thompson, Serena Bugatti, Mattia Bellan, Mattia Congia, Christopher Holroyd, Arthur G. Pratt, Laura White, Louise Warren, Joanna Peel, Rebecca Hands, Gaye Hadfield, Costantino Pitzalis - Nature Medicine 2022 被引用: 279
- Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial
著者: Frances Humby, Patrick Durez, Maya H Buch, Myles Lewis, Hasan Rizvi, Felice Rivellese, Alessandra Nerviani, Giovanni Giorli, Arti Mahto, Carlomaurizio Montecucco, Bernard Lauwerys, Nora Ng, Pauline Ho, Michele Bombardieri, Vasco C. Romão, Patrick Verschueren, Stephen Kelly, Pier Paolo Sainaghi, Nagui Gendi, Bhaskar Dasgupta, Alberto Cauli, Piero Reynolds, Juan D. Cañete, Robert J. Moots, Peter C. Taylor, Christopher J Edwards, John D. Isaacs, Peter Sasieni, Ernest Choy, Costantino Pitzalis, Charlotte Thompson, Serena Bugatti, Mattia Bellan, Mattia Congia, Christopher Holroyd, Arthur G. Pratt, João Eurico Fonseca, Laura White, Louise Warren, Joanna Peel, Rebecca Hands, Liliane Fossati‐Jimack, Gaye Hadfield, Georgina Thorborn, Julio Ramírez, Raquel Celis - The Lancet 2021 被引用: 315
- Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial
著者: Andrew P. Cope, Marianna Jasenecova, Joana C. Vasconcelos, Andrew Filer, Karim Raza, Sumera Qureshi, Maria Antonietta D’Agostino, Iain B. McInnes, John D. Isaacs, Arthur G. Pratt, Benjamin A. Fisher, Christopher D. Buckley, Paul Emery, Pauline Ho, Maya H Buch, Coziana Ciurtin, Dirkjan van Schaardenburg, Thomas Huizinga, René E. M. Toes, Evangelos Georgiou, Joanna Kelly, Caroline Murphy, A Toby Prevost, Sam Norton, Heidi Lempp, Maria Opena, Sujith Subesinghe, Toby Garrood, Bina Menon, Nora Ng, Karen M. Douglas, Christos Koutsianas, Faye A. H. Cooles, Marie Falahee, Irene Echavez-Naguicnic, Anurag Bharadwaj, Michael Villaruel, Ira Pande, David Collins, Suzannah Pegler, Sabrina Raizada, Stefan Siebert, G. Fragoulis, Jesusa Guinto, James Galloway, Andrew I Rutherford, Theresa Barnes, Helen Jeffrey, Yusuf Patel, Michael Batley, Brendan O'Reilly, Srivinisan Venkatachalam, Thomas Sheeran, Claire Gorman, Piero Reynolds, Asad Khan, Nicola Gullick, Siwalik Banerjee, Kulveer Mankia, Deepak Jordan, Jane Rowlands, Mirian Starmans‐Kool, James C. Taylor, Pradip Nandi, Ilfita Sahbudin, Mark Maybury, Samantha Hider, Ann Barcroft, Jeremy McNally, Jo Kitchen, Muhammad Nisar, Vanessa Quick - The Lancet 2024 被引用: 160
- Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement
著者: Peter Nash, Andreas Kerschbaumer, Thomas Dörner, Maxime Dougados, Roy Fleischmann, Klaus Geißler, Iain B. McInnes, Janet Pope, Désirée van der Heijde, Michaela Stoffer, Tsutomu Takeuchi, Michael Trauner, Kevin Winthrop, Maarten de Wit, Daniel Aletaha, Xenofon Baraliakos, Wolf‐Henning Boehncke, Paul Emery, John D. Isaacs, Joel M. Kremer, Eun Bong Lee, Walter P. Maksymowych, Marieke Voshaar, Lai‐Shan Tam, Yoshiya Tanaka, Filip Van den Bosch, René Westhovens, Ricardo Machado Xavier, Josef S Smolen - Annals of the Rheumatic Diseases 2020 被引用: 288
- Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis
著者: Joshua Bennett, Arthur G. Pratt, Richard Dodds, Avan Aihie Sayer, John D. Isaacs - Nature Reviews Rheumatology 2023 被引用: 139
- Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis
著者: Frank Penkava, Martin Del Castillo Velasco‐Herrera, Matthew D. Young, Nicole Yager, L.N. Nwosu, Arthur G. Pratt, Alicia Lledó Lara, Charlotte Guzzo, Ash Maroof, Lira Mamanova, Suzanne Cole, Mirjana Efremova, Davide Simone, Andrew Filer, Chrysothemis C. Brown, Andrew L. Croxford, John D. Isaacs, Sarah A. Teichmann, Paul Bowness, Sam Behjati, Hussein Al‐Mossawi - Nature Communications 2020 被引用: 180
- Cytokines in rheumatoid arthritis — shaping the immunological landscape
著者: Iain B. McInnes, Christopher D. Buckley, John D. Isaacs - Nature Reviews Rheumatology 2015 被引用: 504
- Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
著者: G. Bell, Amy E. Anderson, Julie Diboll, Richard J. Reece, Oliver Eltherington, Rachel A. Harry, Tony Fouweather, Christopher D. Macdonald, TJ Chadwick, Elaine McColl, Jeffrey Dunn, Anne M. Dickinson, Catharien M. U. Hilkens, John D. Isaacs - Annals of the Rheumatic Diseases 2016 被引用: 310
- Basic Mechanisms of JAK Inhibition
著者: Chung Mun Alice Lin, Faye A. H. Cooles, John D. Isaacs - Mediterranean Journal of Rheumatology 2020 被引用: 121
- Differential properties of Janus kinase inhibitors in the treatment of immune-mediated inflammatory diseases
著者: Peter C. Taylor, Ernest Choy, Xenofon Baraliakos, Zoltán Szekanecz, Ricardo Machado Xavier, John D. Isaacs, Sander Strengholt, Julie Parmentier, Ralph Lippe, Yoshiya Tanaka - Lara D. Veeken 2023 被引用: 93
- Integrated safety in tocilizumab clinical trials
著者: Michael Schiff, Joel M. Kremer, Angelika Jahreis, Emma Vernon, John D. Isaacs, Ronald van Vollenhoven - Arthritis Research & Therapy 2011 被引用: 373
- Synovial tissue research: a state-of-the-art review
著者: Carl Orr, Elsa Vieira‐Sousa, David L. Boyle, Maya H Buch, Christopher D. Buckley, Juan D. Cañete, Anca I. Catrina, Ernest Choy, Paul Emery, Ursula Fearon, Andrew Filer, Daniëlle M. Gerlag, Frances Humby, John D. Isaacs, Søren Andreas Just, Bernard Lauwerys, Benoît Le Goff, Antonio Manzo, Trudy McGarry, Iain B. McInnes, Aurélie Najm, Costantino Pitzalis, Arthur G. Pratt, Malcolm Smith, Paul P. Tak, Sander W. Tas, Rogier M. Thurlings, João Eurico Fonseca, Douglas J. Veale - Nature Reviews Rheumatology 2017 被引用: 257
- Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ Study
著者: Joanna Collerton, Carmen Martín-Ruiz, Karen Davies, Catharien M. U. Hilkens, John D. Isaacs, Claire Kolenda, Craig Parker, Michael Dunn, Michael Catt, Carol Jagger, Thomas von Zglinicki, Thomas B. L. Kirkwood - Mechanisms of Ageing and Development 2012 被引用: 424
- Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update
著者: Daniel Aletaha, Andreas Kerschbaumer, Kastriot Kastrati, Christian Dejaco, Maxime Dougados, Iain B. McInnes, Naveed Sattar, Tanja Stamm, Tsutomu Takeuchi, Michael Trauner, Désirée van der Heijde, Marieke Voshaar, Kevin Winthrop, Angelo Ravelli, Neil Betteridge, Gerd R Burmester, J. W. J. Bijlsma, Vivian P. Bykerk, Roberto Caporali, Ernest Choy, Cătălin Codreanu, Bernard Combe, Mary K. Crow, Maarten de Wit, Paul Emery, Roy Fleischmann, Cem Gabay, Merete Lund Hetland, Kimme L Hyrich, Annamaria Iagnocco, John D. Isaacs, Joel M. Kremer, Xavier Mariette, Peter A. Merkel, Eduardo Mysler, Peter Nash, Michael T. Nurmohamed, Karel Pavelká, Gyula Poór, Andrea Rubbert‐Roth, Hendrik Schulze‐Koops, Anja Strangfeld, Yoshiya Tanaka, Josef S Smolen - Annals of the Rheumatic Diseases 2022 被引用: 69
- Novel therapies for immune-mediated inflammatory diseases: What can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis, Crohn's disease and ulcerative colitis?
著者: Kenneth F. Baker, John D. Isaacs - Annals of the Rheumatic Diseases 2017 被引用: 363
- Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials
著者: Felice Rivellese, Alessandra Nerviani, Giovanni Giorli, Louise Warren, Edyta Jaworska, Michele Bombardieri, Myles Lewis, Frances Humby, Arthur G. Pratt, Andrew Filer, Nagui Gendi, Alberto Cauli, Ernest Choy, Iain B. McInnes, Patrick Durez, Christopher J Edwards, Maya H Buch, Elisa Gremese, Peter C. Taylor, Nora Ng, Juan D. Cañete, Sabrina Raizada, Neil D McKay, Deepak R. Jadon, Pier Paolo Sainaghi, Richard Stratton, Michael R. Ehrenstein, Pauline Ho, Joaquim Polido‐Pereira, Bhaskar Dasgupta, Claire Gorman, James Galloway, Hector Chinoy, Désirée van der Heijde, Peter Sasieni, Anne Barton, Costantino Pitzalis, Ahmed S Zayat, Ana Rita Marinho Machado, Andrea Cuervo, Arti Mahto, Cankut Çubuk, Charlotte Rawlings, Chijioke H Mosanya, Christopher D. Buckley, Chris Holroyd, Debbie Maskall, Francesco Carlucci, Georgina Thorborn, Gina Tan, Gloria Lliso-Ribera, Hasan Rizvi, Joanna Peel, João Eurico Fonseca, John D. Isaacs, Julio Ramírez, Laurent Méric de Bellefon, Liliane Fossati-Jimak, Mary Ng’endo Githinji, Mattia Congia, Neal L. Millar, Nirupam Purkayastha, Raquel Celis, Rakhi Seth, Rebecca Hands-Greenwood, Robert Landewé, Simone Perniola, Stefano Alivernini, Stefano Marcia, Stefano Marini, Stephen Kelly, Vasco C. Romão - The Lancet Rheumatology 2023 被引用: 68
- Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers
著者: Philip M. Brown, Arthur G. Pratt, John D. Isaacs - Nature Reviews Rheumatology 2016 被引用: 377
- Tofacitinib in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis
著者: Joel M. Kremer, Zhanguo Li, Stephen Hall, Roy Fleischmann, Mark C. Genovese, E. Martín‐Mola, John D. Isaacs, David Gruben, Gene V. Wallenstein, Sriram Krishnaswami, Samuel H. Zwillich, Tamás Koncz, Richard J. Riese, John Bradley - Annals of Internal Medicine 2013 被引用: 447
- Defective removal of ribonucleotides from DNA promotes systemic autoimmunity
著者: Claudia Günther, Barbara Kind, Martin A.M. Reijns, Nicole Berndt, Manuel Martínez‐Bueno, Christine Wolf, Victoria Tüngler, Osvaldo Chara, Young Ae Lee, Norbert Hübner, Louise S. Bicknell, S. Blum, Claudia Krug, Franziska Schmidt, Stefanie Kretschmer, Sarah Koss, Katy R. Astell, Georgia Ramantani, Anja Bauerfeind, David Morris, Deborah S. Cunninghame Graham, Doryen Bubeck, Andrea Leitch, Stuart H. Ralston, Elizabeth A. Blackburn, Manfred Gahr, Torsten Witte, Timothy J. Vyse, Inga Melchers, Elisabeth Mangold, Markus M. Nöthen, Martin Aringer, Annegret Kuhn, Kirsten Lüthke, L. Unger, Annette Bley, Alice Lorenzi, John D. Isaacs, Dimitra Alexopoulou, Karsten Conrad, Andreas Dahl, Axel Roers, Marta E. Alarcón‐Riquelme, Andrew P. Jackson, Min Ae Lee-Kirsch - Journal of Clinical Investigation 2014 被引用: 222
- Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment
著者: Rebeccah J. Mathews, James Robinson, M. Battellino, Chi Huey Wong, John Taylor, Steve Eyre, Sarah M. Churchman, Anthony G. Wilson, John D. Isaacs, Kimme L Hyrich, Anne Barton, Darren Plant, Sinisa Savic, Graham P. Cook, Piercarlo Sarzi‐Puttini, Paul Emery, Jennifer H. Barrett, Ann W Morgan, Michael McDermott - Annals of the Rheumatic Diseases 2013 被引用: 197
- Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients
著者: Matthew J. Wood, Adam Leckenby, Gary Reynolds, Rachel Spiering, Arthur G. Pratt, Kenneth S. Rankin, John D. Isaacs, Muzlifah Haniffa, Simon Milling, Catharien M. U. Hilkens - JCI Insight 2019 被引用: 119
- Why remission is not enough: underlying disease mechanisms in RA that prevent cure
著者: Georg Schett, Yoshiya Tanaka, John D. Isaacs - Nature Reviews Rheumatology 2020 被引用: 86
- Symptom-based stratification of patients with primary Sjögren's syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised clinical trials
著者: Jessica Tarn, Nadia Howard-Tripp, Dennis Lendrem, Xavier Mariette, Alain Saraux, Valérie Devauchelle‐Pensec, Raphaèle Séror, Andrew Skelton, Katherine James, Peter McMeekin, Shereen Al-Ali, Katie L. Hackett, Clare Lendrem, Ben Hargreaves, John Casement, Sheryl Mitchell, Simon J Bowman, Elizabeth Price, Colin Pease, Paul Emery, Peter Lanyon, John Hunter, Monica Gupta, Michele Bombardieri, Nurhan Sutcliffe, Costantino Pitzalis, John McLaren, Annie Cooper, Marian Regan, Ian Giles, David Isenberg, V. Saravanan, David Coady, Bhaskar Dasgupta, Neil McHugh, Steven Young‐Min, Robert J. Moots, Nagui Gendi, Mohammed Akil, Bridget Griffiths, Svein Joar Auglænd Johnsen, Katrine Brække Norheim, Roald Omdal, Deborah Stocken, Colin Everett, Catherine Fernandez, John D. Isaacs, Jacques‐Eric Gottenberg, Valérie Devauchelle-Pensec, Philippe Dieudé, Jean Jacques Dubost, Anne-Laure Fauchais, Vincent Goëb, É. Hachulla, Claire Larroche, Véronique Le Guern, Jacques Morel, Aleth Perdriger, Xavier Puéchal, S. Rist, Damien Sen, Jean Sibilia, Olivier Vittecoq, Joëlle Bénessiano, Sarah Tubiana, Karine Inamo, Stanie Gaëte, Djilali Batouche, Domitille Molinari, Mickael Randrianandrasana, Isabelle Pane, Adeline Abbé, Gabriel Baron, Philippe Ravaud, Jacques-Eric Gottenberg, Philippe Ravaud, Xavier Puéchal, Véronique Le Guern, Jean Sibilia, Claire Larroche, Alain Saraux, Valérie Devauchelle-Pensec, Jacques Morel, Gilles Hayem, P.Y. Hatron, Aleth Perdriger, Damien Sene, Charles Zarnitsky, Djilali Batouche, Valérie Furlan, Joëlle Bénessiano, Élodie Perrodeau, Raphaèle Séror, Xavier Mariette, Samuel M. Brown, N. Navarro, C Pitzalis, Paul Emery, Sue Pavitt, Joanne Gray ほか 141 名 - The Lancet Rheumatology 2019 被引用: 137
- Immunogenicity of biologic agents in rheumatology
著者: Vibeke Strand, João Gonçalves, John D. Isaacs - Nature Reviews Rheumatology 2020 被引用: 99
