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René E. M. Toes

1996–2025 年に発表

217
論文数
40,331
被引用数
110
h 指数
205
i10 指数

被引用数

René E. M. Toes の年別被引用数1932 年: 被引用 1 件1979 年: 被引用 1 件1993 年: 被引用 1 件1996 年: 被引用 6 件1997 年: 被引用 10 件1998 年: 被引用 51 件1999 年: 被引用 116 件2000 年: 被引用 199 件2001 年: 被引用 195 件2002 年: 被引用 280 件2003 年: 被引用 212 件2004 年: 被引用 235 件2005 年: 被引用 263 件2006 年: 被引用 266 件2007 年: 被引用 340 件2008 年: 被引用 336 件2009 年: 被引用 363 件2010 年: 被引用 426 件2011 年: 被引用 402 件2012 年: 被引用 415 件2013 年: 被引用 396 件2014 年: 被引用 442 件2015 年: 被引用 486 件2016 年: 被引用 402 件2017 年: 被引用 440 件2018 年: 被引用 404 件2019 年: 被引用 1,246 件2020 年: 被引用 1,223 件2021 年: 被引用 1,206 件2022 年: 被引用 985 件2023 年: 被引用 737 件2024 年: 被引用 1,122 件2025 年: 被引用 604 件2026 年: 被引用 11 件1933〜1978 年は被引用が無いため表示していません1980〜1992 年は被引用が無いため表示していません1994〜1995 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 3,753 件、この内訳の 24.4%中国: 引用元論文 1,358 件、この内訳の 8.8%イギリス: 引用元論文 1,315 件、この内訳の 8.5%オランダ: 引用元論文 1,005 件、この内訳の 6.5%ドイツ: 引用元論文 985 件、この内訳の 6.4%フランス: 引用元論文 600 件、この内訳の 3.9%イタリア: 引用元論文 598 件、この内訳の 3.9%スウェーデン: 引用元論文 523 件、この内訳の 3.4%日本: 引用元論文 504 件、この内訳の 3.3%オーストラリア: 引用元論文 481 件、この内訳の 3.1%カナダ: 引用元論文 417 件、この内訳の 2.7%スペイン: 引用元論文 328 件、この内訳の 2.1%
0%24.4%その他 23%

機関

分野

  • Medicine44.2%
  • Immunology and Microbiology32.1%
  • Biochemistry, Genetics and Molecular Biology20.3%
  • Neuroscience0.7%
  • Nursing0.6%
  • Dentistry0.4%
  • その他1.7%

トピック

  • Immunotherapy and Immune Responses7.6%
  • T-cell and B-cell Immunology7.5%
  • Immune Cell Function and Interaction6.9%
  • Rheumatoid Arthritis Research and Therapies6.6%
  • Systemic Lupus Erythematosus Research3.6%
  • Monoclonal and Polyclonal Antibodies Research2.9%
  • その他64.9%

共著者

全論文

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  1. Genetics of rheumatoid arthritis contributes to biology and drug discovery

    著者: Yukinori Okada, Di Wu, Gosia Trynka, Towfique Raj, Chikashi Terao, Katsunori Ikari, Yuta Kochi, Koichiro Ohmura, Akari Suzuki, Shinji Yoshida, Robert Graham, Arun Manoharan, Ward Ortmann, Tushar Bhangale, Joshua C. Denny, Robert J. Carroll, Anne E. Eyler, Jeffrey D. Greenberg, Joel M. Kremer, Dimitrios A. Pappas, Lei Jiang, Jian Yin, Lingying Ye, Ding‐Feng Su, Jian Yang, Gang Xie, Ed Keystone, Harm-Jan Westra, Tõnu Esko, Andres Metspalu, Xuezhong Zhou, Namrata Gupta, Daniel B. Mirel, Eli A. Stahl, Dorothée Diogo, Jing Cui, Katherine P. Liao, Michael H. Guo, Keiko Myouzen, Takahisa Kawaguchi, Marieke J. H. Coenen, Piet L. C. M. van Riel, Mart A F J van de Laar, Henk‐Jan Guchelaar, T. Huizinga, Philippe Dieudé, Xavier Mariette, S. Louis Bridges, Alexandra Zhernakova, René E. M. Toes, Paul P. Tak, Corinne Miceli‐Richard, So‐Young Bang, Hye‐Soon Lee, Javier Martı́n, Miguel Á. González‐Gay, Luis Rodríguez‐Rodríguez, Solbritt Rantapää‐Dahlqvist, Lisbeth Ärlestig, Hyon K. Choi, Yoichiro Kamatani, Pilar Galán, Mark Lathrop, Steve Eyre, John Bowes, Anne Barton, Niek de Vries, Larry W. Moreland, Lindsey A. Criswell, Elizabeth W. Karlson, Atsuo Taniguchi, Ryo Yamada, Michiaki Kubo, Jun S. Liu, Sang‐Cheol Bae, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Soumya Raychaudhuri, Barbara E. Stranger, Philip L. De Jager, Lude Franke, Peter M. Visscher, Matthew A. Brown, Hisashi Yamanaka, Tsuneyo Mimori, Atsushi Takahashi, Huji Xu, Timothy W. Behrens, Katherine Siminovitch, Shigeki Momohara, Fumihiko Matsuda, Kazuhiko Yamamoto, Robert M. Plenge - Nature 2013 被引用: 2,499

  2. Neutrophil Extracellular Traps (NETs) Take the Central Stage in Driving Autoimmune Responses

    著者: Esther Fousert, René E. M. Toes, Jyaysi Desai - Cells 2020 被引用: 270

  3. Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

    著者: B.J.E. de Lange-Brokaar, Andreea Ioan‐Facsinay, Gerjo J. V. M. van Osch, A.-M. Zuurmond, Jan W. Schoones, René E. M. Toes, T. Huizinga, M. Kloppenburg - Osteoarthritis and Cartilage 2012 被引用: 672

  4. Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial

    著者: Andrew P. Cope, Marianna Jasenecova, Joana C. Vasconcelos, Andrew Filer, Karim Raza, Sumera Qureshi, Maria Antonietta D’Agostino, Iain B. McInnes, John D. Isaacs, Arthur G. Pratt, Benjamin A. Fisher, Christopher D. Buckley, Paul Emery, Pauline Ho, Maya H Buch, Coziana Ciurtin, Dirkjan van Schaardenburg, Thomas Huizinga, René E. M. Toes, Evangelos Georgiou, Joanna Kelly, Caroline Murphy, A Toby Prevost, Sam Norton, Heidi Lempp, Maria Opena, Sujith Subesinghe, Toby Garrood, Bina Menon, Nora Ng, Karen M. Douglas, Christos Koutsianas, Faye A. H. Cooles, Marie Falahee, Irene Echavez-Naguicnic, Anurag Bharadwaj, Michael Villaruel, Ira Pande, David Collins, Suzannah Pegler, Sabrina Raizada, Stefan Siebert, G. Fragoulis, Jesusa Guinto, James Galloway, Andrew I Rutherford, Theresa Barnes, Helen Jeffrey, Yusuf Patel, Michael Batley, Brendan O'Reilly, Srivinisan Venkatachalam, Thomas Sheeran, Claire Gorman, Piero Reynolds, Asad Khan, Nicola Gullick, Siwalik Banerjee, Kulveer Mankia, Deepak Jordan, Jane Rowlands, Mirian Starmans‐Kool, James C. Taylor, Pradip Nandi, Ilfita Sahbudin, Mark Maybury, Samantha Hider, Ann Barcroft, Jeremy McNally, Jo Kitchen, Muhammad Nisar, Vanessa Quick - The Lancet 2024 被引用: 160

  5. T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

    著者: Stephen P. Schoenberger, René E. M. Toes, Ellen I. H. van der Voort, Rienk Offringa, Cornelis J.M. Melief - Nature 1998 被引用: 2,624

  6. Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

    著者: Ulrike Harre, Dan Georgess, Holger Bang, Aline Bözec, Roland Axmann, Elena Ossipova, Per‐Johan Jakobsson, Wolfgang Baum, Falk Nimmerjahn, Eszter Szarka, Gabriella Sármay, Grit Krumbholz, Elena Neumann, René E. M. Toes, Hans Ulrich Scherer, Anca I. Catrina, Lars Klareskog, Pierre Jurdic, Georg Schett - Journal of Clinical Investigation 2012 被引用: 708

  7. Glycobiology of rheumatic diseases

    著者: Theresa Kissel, René E. M. Toes, Thomas W. J. Huizinga, Manfred Wuhrer - Nature Reviews Rheumatology 2022 被引用: 94

  8. Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis

    著者: Hendy Kristyanto, N. Blomberg, Linda M. Slot, Ellen I. H. van der Voort, Priscilla F. Kerkman, Aleida M. Bakker, L.E. Burgers, Robin M. ten Brinck, Annette H M van der Helm–van Mil, Hergen Spits, Dominique Baeten, T. Huizinga, René E. M. Toes, Hans Ulrich Scherer - Science Translational Medicine 2020 被引用: 114

  9. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

    著者: Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Steve Eyre, John Bowes, Dorothée Diogo, Annette Lee, Anne Barton, Paul Martin, Alexandra Zhernakova, Eli A. Stahl, Sébastien Viatte, Kate McAllister, Christopher I. Amos, Leonid Padyukov, René E. M. Toes, T. Huizinga, Cisca Wijmenga, Gosia Trynka, Lude Franke, Harm-Jan Westra, Lars Alfredsson, Xinli Hu, Cynthia Sandor, Paul I. W. de Bakker, Sonia Dávila, Chiea Chuen Khor, Khai Koon Heng, Robert Andrews, Sarah Edkins, Sarah Hunt, Cordelia Langford, Deborah Symmons, Patrick Concannon, Suna Önengüt-Gümüşcü, Stephen S. Rich, Panos Deloukas, Miguel Á. González‐Gay, Luis Rodríguez‐Rodríguez, Lisbeth Ärlsetig, Javier Martı́n, Solbritt Rantapää‐Dahlqvist, Robert M. Plenge, Soumya Raychaudhuri, Lars Klareskog, Peter K. Gregersen, Jane Worthington - Nature Genetics 2012 被引用: 677

  10. Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors

    著者: Emma C. de Moel, Elisa A. Rozeman, Ellen Kapiteijn, Els M.E. Verdegaal, Annette Grummels, Jaap Bakker, T. Huizinga, John B.A.G. Haanen, René E. M. Toes, Diane van der Woude - Cancer Immunology Research 2018 被引用: 195

  11. Determining in which pre-arthritis stage HLA-shared epitope alleles and smoking exert their effect on the development of rheumatoid arthritis

    著者: Fenne Wouters, M. Maurits, Laurette van Boheemen, Marloes Verstappen, Kulveer Mankia, X. Matthijssen, Annemarie L Dorjée, Paul Emery, Rachel Knevel, Dirkjan van Schaardenburg, René E. M. Toes, Annette H M van der Helm–van Mil - Annals of the Rheumatic Diseases 2021 被引用: 83

  12. Inflammatory Cells in Patients with Endstage Knee Osteoarthritis: A Comparison between the Synovium and the Infrapatellar Fat Pad

    著者: Inge R. Klein‐Wieringa, B.J.E. de Lange-Brokaar, Erlangga Yusuf, Stefan N. Andersen, Joanneke C. Kwekkeboom, Herman M. Kroon, Gerjo J. V. M. van Osch, Anne‐Marie Zuurmond, V. Stojanovic‐Susulic, Rob G. H. H. Nelissen, René E. M. Toes, M. Kloppenburg, Andreea Ioan‐Facsinay - The Journal of Rheumatology 2016 被引用: 170

  13. Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation

    著者: Theresa Kissel, Changrong Ge, Lise Hafkenscheid, Joanneke C. Kwekkeboom, Linda M. Slot, Marco Cavallari, Yibo He, Karin A. van Schie, Rochelle D. Vergroesen, Arieke S. B. Kampstra, Sanne Reijm, Gerrie Stoeken‐Rijsbergen, Carolien A. M. Koeleman, Lenard M. Voortman, Laura H. Heitman, Bingze Xu, Ger J.M. Pruijn, Manfred Wuhrer, Theo Rispens, T. Huizinga, Hans Ulrich Scherer, Michael Reth, Rikard Holmdahl, René E. M. Toes - Science Advances 2022 被引用: 74

  14. Transient expression of FOXP3 in human activated nonregulatory CD4 + T cells

    著者: Jun Wang, Andreea Ioan‐Facsinay, Ellen I. H. van der Voort, T. Huizinga, René E. M. Toes - European Journal of Immunology 2006 被引用: 996

  15. Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease

    著者: René Pfeifle, Tobias Rothe, Natacha Ipseiz, Hans Ulrich Scherer, Stephan Culemann, Ulrike Harre, Jochen A. Ackermann, Martina Seefried, Arnd Kleyer, Stefan Uderhardt, Haugg Benjamin, Axel J. Hueber, Patrick Daum, Gordon F. Heidkamp, Changrong Ge, Sybille Böhm, Anja Lux, Wolfgang Schuh, Iryna Magorivska, Kutty Selva Nandakumar, Erik Lönnblom, Christoph Becker, Diana Dudziak, Manfred Wuhrer, Yoann Rombouts, Carolien A. M. Koeleman, René E. M. Toes, Thomas Winkler, Rikard Holmdahl, Martin Herrmann, Stephan Blüml, Falk Nimmerjahn, Georg Schett, Gerhard Krönke - Nature Immunology 2016 被引用: 311

  16. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

    著者: Eli A. Stahl, Soumya Raychaudhuri, Elaine F. Remmers, Gang Xie, Stephen Eyre, Brian Thomson, Yonghong Li, Fina Kurreeman, Alexandra Zhernakova, Anne Hinks, Candace Guiducci, Robert Chen, Lars Alfredsson, Christopher I. Amos, Kristin Ardlie, Anne Barton, John Bowes, Elisabeth Brouwer, Noël P. Burtt, Joseph J. Catanese, Jonathan Coblyn, Marieke J. H. Coenen, Karen H. Costenbader, Lindsey A. Criswell, J. Bart A. Crusius, Jing Cui, Paul I. W. de Bakker, Philip L. De Jager, Bo Ding, Paul Emery, Edward Flynn, Pille Harrison, Lynne J. Hocking, T. Huizinga, Daniel L. Kastner, Xiayi Ke, Annette T. Lee, Xiangdong Liu, Paul Martin, Ann W Morgan, Leonid Padyukov, Marcel D. Posthumus, Timothy R. D. J. Radstake, David M. Reid, Mark Seielstad, Michael F. Seldin, Nancy A. Shadick, Sophia Steer, Paul P. Tak, Wendy Thomson, Annette H M van der Helm–van Mil, Irene E. van der Horst‐Bruinsma, C. Ellen van der Schoot, Piet L. C. M. van Riel, Michael E. Weinblatt, Anthony G. Wilson, Gertjan Wolbink, B P Wordsworth, Cisca Wijmenga, Elizabeth W. Karlson, René E. M. Toes, Niek de Vries, Ann B. Begovich, Jane Worthington, Katherine Siminovitch, Peter K. Gregersen, Lars Klareskog, Robert M. Plenge - Nature Genetics 2010 被引用: 1,279

  17. Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

    著者: Jing Shi, Rachel Knevel, Parawee Suwannalai, Michael P. van der Linden, George M. C. Janssen, Peter A. van Veelen, Nivine Levarht, Annette H M van der Helm–van Mil, Anthony Cerami, T. Huizinga, René E. M. Toes, Leendert A. Trouw - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 被引用: 573

  18. A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

    著者: S.W. Scally, Jan Petersen, Soi Cheng Law, Nadine L. Dudek, Hendrik J. Nel, Khai Lee Loh, Lakshmi C. Wijeyewickrema, Sidonia B. G. Eckle, Jurgen van Heemst, Robert N. Pike, James McCluskey, René E. M. Toes, Nicole L. La Gruta, Anthony W. Purcell, Hugh H. Reid, Ranjeny Thomas, Jamie Rossjohn - The Journal of Experimental Medicine 2013 被引用: 412

  19. A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis

    著者: Yibo He, Changrong Ge, Àlex Moreno‐Giró, Bingze Xu, Christian M. Beusch, Katalin Sándor, Jie Su, Lei Cheng, Erik Lönnblom, Christina Lundqvist, Linda M. Slot, Dongmei Tong, Vilma Urbonaviciute, Bibo Liang, Taotao Li, Gonzalo Fernandez Lahore, Mike Aoun, Vivianne Malmström, Theo Rispens, Patrik Ernfors, Camilla I. Svensson, Hans Ulrich Scherer, René E. M. Toes, Inger Gjertsson, Olov Ekwall, Roman A. Zubarev, Rikard Holmdahl - Nature Communications 2023 被引用: 62

  20. Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis

    著者: Amee Sonigra, Hendrik J. Nel, Pascale Wehr, Nishta Ramnoruth, Swati Patel, Karin A. van Schie, Maxwell W. Bladen, Ahmed M. Mehdi, Joanne Tesiram, Meghna Talekar, Jamie Rossjohn, Hugh H. Reid, Frederik E. Stuurman, Helen Roberts, Phillip Vecchio, Ian Gourley, Mark Rigby, Stéphane Bécart, René E. M. Toes, Hans Ulrich Scherer, Kim‐Anh Lê Cao, Kim Campbell, Ranjeny Thomas - JCI Insight 2022 被引用: 51

  21. The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype

    著者: Inge R. Klein‐Wieringa, M. Kloppenburg, Y.M. Bastiaansen-Jenniskens, Erlangga Yusuf, Joanneke C. Kwekkeboom, H. El-Bannoudi, Rob G. H. H. Nelissen, A.-M. Zuurmond, V. Stojanovic‐Susulic, Gerjo J.V.M. van Osch, René E. M. Toes, Andreea Ioan‐Facsinay - Annals of the Rheumatic Diseases 2011 被引用: 275

  22. From risk to chronicity: evolution of autoreactive B cell and antibody responses in rheumatoid arthritis

    著者: Hans Ulrich Scherer, Diane van der Woude, René E. M. Toes - Nature Reviews Rheumatology 2022 被引用: 84

  23. Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications

    著者: Theresa Kissel, Sanne Reijm, LM Slot, Marco Cavallari, CM Wortel, RD Vergroesen, Gerrie Stoeken‐Rijsbergen, JC Kwekkeboom, ASB Kampstra, EWN Levarht, Jan W. Drijfhout, Holger Bang, KM Bonger, GMC Janssen, Peter A. van Veelen, T. Huizinga, Hans Ulrich Scherer, Michael Reth, René E. M. Toes - Annals of the Rheumatic Diseases 2020 被引用: 119

  24. Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

    著者: Yoann Rombouts, Ewoud Ewing, Lotte A van de Stadt, Maurice H. J. Selman, Leendert A. Trouw, André M. Deelder, T. Huizinga, Manfred Wuhrer, Dirkjan van Schaardenburg, René E. M. Toes, Hans Ulrich Scherer - Annals of the Rheumatic Diseases 2013 被引用: 280