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Rienk Offringa

1989–2025 年に発表

99
論文数
19,622
被引用数
78
h 指数
99
i10 指数

被引用数

Rienk Offringa の年別被引用数1979 年: 被引用 1 件1990 年: 被引用 5 件1991 年: 被引用 22 件1992 年: 被引用 19 件1993 年: 被引用 17 件1994 年: 被引用 14 件1995 年: 被引用 24 件1996 年: 被引用 24 件1997 年: 被引用 18 件1998 年: 被引用 67 件1999 年: 被引用 134 件2000 年: 被引用 233 件2001 年: 被引用 213 件2002 年: 被引用 294 件2003 年: 被引用 280 件2004 年: 被引用 280 件2005 年: 被引用 262 件2006 年: 被引用 218 件2007 年: 被引用 238 件2008 年: 被引用 245 件2009 年: 被引用 217 件2010 年: 被引用 198 件2011 年: 被引用 175 件2012 年: 被引用 204 件2013 年: 被引用 160 件2014 年: 被引用 175 件2015 年: 被引用 165 件2016 年: 被引用 166 件2017 年: 被引用 121 件2018 年: 被引用 100 件2019 年: 被引用 330 件2020 年: 被引用 376 件2021 年: 被引用 413 件2022 年: 被引用 349 件2023 年: 被引用 245 件2024 年: 被引用 368 件2025 年: 被引用 246 件2026 年: 被引用 8 件1980〜1989 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 2,261 件、この内訳の 31.7%中国: 引用元論文 601 件、この内訳の 8.4%ドイツ: 引用元論文 562 件、この内訳の 7.9%オランダ: 引用元論文 497 件、この内訳の 7%イギリス: 引用元論文 426 件、この内訳の 6%フランス: 引用元論文 318 件、この内訳の 4.5%イタリア: 引用元論文 224 件、この内訳の 3.1%オーストラリア: 引用元論文 199 件、この内訳の 2.8%日本: 引用元論文 191 件、この内訳の 2.7%スイス: 引用元論文 188 件、この内訳の 2.6%カナダ: 引用元論文 172 件、この内訳の 2.4%スウェーデン: 引用元論文 120 件、この内訳の 1.7%
0%31.7%その他 19.2%

機関

分野

  • Immunology and Microbiology46.9%
  • Medicine33.3%
  • Biochemistry, Genetics and Molecular Biology17.1%
  • Engineering0.8%
  • Neuroscience0.8%
  • Agricultural and Biological Sciences0.3%
  • その他0.8%

トピック

  • Immunotherapy and Immune Responses18.3%
  • Immune Cell Function and Interaction9.8%
  • T-cell and B-cell Immunology8.6%
  • Cancer Immunotherapy and Biomarkers7.5%
  • CAR-T cell therapy research5.3%
  • vaccines and immunoinformatics approaches3.4%
  • その他47.1%

共著者

全論文

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  1. The expanding role for small molecules in immuno-oncology

    著者: Rienk Offringa, Lisa Kötzner, Bayard R. Huck, Klaus Urbahns - Nature Reviews Drug Discovery 2022 被引用: 121

  2. T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

    著者: Stephen P. Schoenberger, René E. M. Toes, Ellen I. H. van der Voort, Rienk Offringa, Cornelis J.M. Melief - Nature 1998 被引用: 2,624

  3. Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

    著者: Gemma G. Kenter, Marij J.P. Welters, A. Rob P.M. Valentijn, Margriet J. Löwik, Dorien M. A. Berends-van der Meer, Annelies P.G. Vloon, Farah Essahsah, Lorraine M. Fathers, Rienk Offringa, Jan W. Drijfhout, Amon R. Wafelman, Jaap Oostendorp, Gert Jan Fleuren, Sjoerd H. van der Burg, Cornelis J.M. Melief - New England Journal of Medicine 2009 被引用: 1,085

  4. Prevailing Role of Contact Guidance in Intrastromal T-cell Trapping in Human Pancreatic Cancer

    著者: Natalie Hartmann, Nathalia A. Giese, Thomas Giese, Isabel Poschke, Rienk Offringa, Jens Werner, Eduard Ryschich - Clinical Cancer Research 2014 被引用: 244

  5. Superior induction of anti‐tumor CTL immunity by extended peptide vaccines involves prolonged, DC‐focused antigen presentation

    著者: Martijn S. Bijker, Susan J. F. van den Eeden, Kees L. M. C. Franken, Cornelis J.M. Melief, Sjoerd H. van der Burg, Rienk Offringa - European Journal of Immunology 2008 被引用: 231

  6. Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy

    著者: Christina Kober, Julian Roewe, Norbert Schmees, Lars Roese, Ulrike Roehn, Benjamin Bader, Detlef Stoeckigt, Florian Prinz, Mátyás Gorjánácz, Helge G. Roider, Catherine Olesch, Gabriele Leder, Horst Irlbacher, Ralf Lesche, Julien Lefranc, Mine Oezcan-Wahlbrink, Ankita Sati Batra, Nirmeen Elmadany, Rafael Carretero, Katharina Sahm, Iris Oezen, Frederik Cichon, Daniel Baumann, Ahmed Sadik, Christiane A. Opitz, Hilmar Weinmann, Ingo V. Hartung, Bertolt Kreft, Rienk Offringa, Michael Platten, Ilona Gutcher - Journal for ImmunoTherapy of Cancer 2023 被引用: 82

  7. Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy

    著者: Chin Leng Tan, Katharina A.M. Lindner, Tamara Boschert, Zibo Meng, Aaron Rodriguez Ehrenfried, Alice De Roia, Gordon Haltenhof, A. Faenza, Francesco Imperatore, Lukas Bunse, John M. Lindner, Richard P. Harbottle, Miriam Ratliff, Rienk Offringa, Isabel Poschke, Michael Platten, Edward W. Green - Nature Biotechnology 2024 被引用: 71

  8. Characterization of single neurons reprogrammed by pancreatic cancer

    著者: Vera Thiel, Simon Renders, Jasper Panten, Nicolas Dross, Katharina Bauer, Daniel Azorín, Vanessa Henriques, Vanessa Vogel, Corinna Klein, Aino‐Maija Leppä, Isabel Barriuso-Ortega, Jonas Schwickert, Iordanis Ourailidis, Julian Mochayedi, Jan‐Philipp Mallm, Carsten Müller‐Tidow, Hannah Monyer, John P. Neoptolemos, Thilo Hackert, Oliver Stegle, Duncan T. Odom, Rienk Offringa, Albrecht Stenzinger, Frank Winkler, Martin R. Sprick, Andreas Trumpp - Nature 2025 被引用: 101

  9. CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund’s Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity

    著者: Martijn S. Bijker, Susan J. F. van den Eeden, Kees L. M. C. Franken, Cornelis J.M. Melief, Rienk Offringa, Sjoerd H. van der Burg - The Journal of Immunology 2007 被引用: 282

  10. ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation

    著者: Rui Sun, Zibo Meng, Hye-Yoon Lee, Rienk Offringa, Christof Niehrs - Cell chemical biology 2023 被引用: 40

  11. The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones

    著者: Isabel Poschke, Jessica C. Hassel, Aaron Rodriguez-Ehrenfried, Katharina A.M. Lindner, Ignacio Heras‐Murillo, Lena M. Appel, Johanna Lehmann, Tanja Lövgren, Stina L. Wickström, Claudia Lauenstein, Jasmin Roth, Anna‐Katharina König, John B.A.G. Haanen, Joost van den Berg, Rolf Kiessling, Frank Bergmann, Michael Floßdorf, Oliver Strobel, Rienk Offringa - Clinical Cancer Research 2020 被引用: 90

  12. Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma

    著者: Isabel Poschke, Marta Faryna, Frank Bergmann, Michael Floßdorf, Claudia Lauenstein, Jennifer Hermes, Ulf Hinz, Thomas Hank, Roland Ehrenberg, Michael Volkmar, Martin Löewer, Hanno Glimm, Thilo Hackert, Martin R. Sprick, Thomas Höfer, Andreas Trumpp, Niels Halama, Jessica C. Hassel, Oliver Strobel, Markus W. Büchler, Uğur Şahin, Rienk Offringa - OncoImmunology 2016 被引用: 96

  13. High Number of Intraepithelial CD8+ Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer

    著者: Sytse J. Piersma, Ekaterina S. Jordanova, Mariëtte I.E. van Poelgeest, Kitty M.C. Kwappenberg, Jeanette M. van der Hulst, Jan W. Drijfhout, Cornelis J.M. Melief, Gemma G. Kenter, Gert Jan Fleuren, Rienk Offringa, Sjoerd H. van der Burg - Cancer Research 2007 被引用: 419

  14. Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

    著者: Daniel Baumann, Tanja Hägele, Julian Mochayedi, Jennifer Drebant, Caroline Vent, Sven Blobner, Julia Han Noll, Irena Nickel, Corinna Schumacher, Sophie Luise Boos, Aline Daniel, Susann Wendler, Michael Volkmar, Oliver Strobel, Rienk Offringa - Nature Communications 2020 被引用: 73

  15. Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer

    著者: Zibo Meng, Aaron Rodriguez Ehrenfried, Chin Leng Tan, Laura K. Steffens, Hannes Kehm, Stefan Zens, Claudia Lauenstein, A. Paul, Marius Schwab, Jonas D. Förster, Mogjiborahman Salek, Angelika B. Riemer, Heshui Wu, Christoph Eckert, Carl-Stephan Leonhardt, Oliver Strobel, Michael Volkmar, Isabel Poschke, Rienk Offringa - Science Translational Medicine 2023 被引用: 44

  16. Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

    著者: Jan Paul Medema, Joan de Jong, Lucy T.C. Peltenburg, Els M.E. Verdegaal, Arko Gorter, Sandra A. Bres, Kees L. M. C. Franken, Michael Hahne, Juan Pablo Albar, Cornelis J.M. Melief, Rienk Offringa - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 被引用: 350

  17. T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction

    著者: J. Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf‐Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin V. Luetke-Eversloh, Sven Golfier, Oliver von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse N. Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda - 2022 被引用: 35

  18. Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides

    著者: Sander Zwaveling, Sandra C. Ferreira Mota, Jan Nouta, Mark E. Johnson, Grayson B. Lipford, Rienk Offringa, Sjoerd H. van der Burg, Cornelis J.M. Melief - The Journal of Immunology 2002 被引用: 415

  19. p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition

    著者: Daniel Baumann, Jennifer Drebant, Tanja Hägele, Luisa Burger, Clara Serger, Claudia Lauenstein, Przemyslaw Dudys, Gerrit Erdmann, Rienk Offringa - Journal for ImmunoTherapy of Cancer 2021 被引用: 51

  20. T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction

    著者: Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin Luetke-Eversloh, Sven Golfier, Oliver Von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse Nur-Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda - OncoImmunology 2021 被引用: 37

  21. CD25+ cell depletion hastens the onset of severe disease in collagen‐induced arthritis

    著者: Mary E. Morgan, Roger P.M. Sutmuller, Hendrik J. Witteveen, Leonie M. van Duivenvoorde, Eric Zanelli, Cornelis J.M. Melief, A. J. Snijders, Rienk Offringa, René R. P. de Vries, René E. M. Toes - Arthritis & Rheumatism 2003 被引用: 303

  22. Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses

    著者: Roger P.M. Sutmuller, Leonie M. van Duivenvoorde, Andrea van Elsas, Ton N. Schumacher, Manon E. Wildenberg, James P. Allison, René E. M. Toes, Rienk Offringa, Cornelis J.M. Melief - The Journal of Experimental Medicine 2001 被引用: 1,013

  23. Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine

    著者: Marij J.P. Welters, Gemma G. Kenter, Sytse J. Piersma, Annelies P.G. Vloon, Margriet J.G. Löwik, Dorien M. A. Berends-van der Meer, Jan W. Drijfhout, A. Rob P.M. Valentijn, Amon R. Wafelman, Jaap Oostendorp, Gert Jan Fleuren, Rienk Offringa, Cornelis J.M. Melief, Sjoerd H. van der Burg - Clinical Cancer Research 2008 被引用: 368

  24. Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.

    著者: René E. M. Toes, Rienk Offringa, R. Blom, Cornelis J.M. Melief, W. Martin Kast - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 被引用: 293